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RBM6 Gene

protein-coding   GIFtS: 51
GCID: GC03P049952

RNA Binding Motif Protein 6

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RNA Binding Motif Protein 61 2     HLC-112
DEF32 3 5     NY-LU-122
Lung Cancer Antigen NY-LU-122 3     g162
RNA-Binding Motif Protein 62 3     Lung Cancer Protooncogene 112
RNA-Binding Protein DEF-32 3     RNA-Binding Protein 62
3G22     Protein G163
DEF-32     

External Ids:    HGNC: 99031   Entrez Gene: 101802   Ensembl: ENSG000000045347   OMIM: 6068865   UniProtKB: P783323   

Export aliases for RBM6 gene to outside databases

Previous GC identifers: GC03M049873 GC03M050042 GC03P049831 GC03P049936


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RBM6 Gene:
RBM6 (RNA binding motif protein 6) is a protein-coding gene. Diseases associated with RBM6 include chronic cystitis, and lung cancer. GO annotations related to this gene include RNA binding and nucleotide binding. An important paralog of this gene is RBM10.

UniProtKB/Swiss-Prot: RBM6_HUMAN, P78332
Function: Specifically binds poly(G) RNA homopolymers in vitro

Gene Wiki entry for RBM6 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the RBM6 gene promoter:
         STAT1   STAT4   STAT1beta   Tal-1beta   STAT1alpha   E47   Gfi-1   AREB6   STAT2   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRBM6 promoter sequence
   Search Chromatin IP Primers for RBM6

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RBM6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p21.3   Ensembl cytogenetic band:  3p21.31   HGNC cytogenetic band: 3p21.3

RBM6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RBM6 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P049952:  view genomic region     (about GC identifiers)

Start:
49,977,440 bp from pter      End:
50,137,478 bp from pter
Size:
160,039 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RBM6_HUMAN, P78332 (See protein sequence)
Recommended Name: RNA-binding protein 6  
Size: 1123 amino acids; 128644 Da
Subunit: May interact with FAM168B
Secondary accessions: O60549 O75524 Q86SS3
Alternative splicing: 2 isoforms:  P78332-1   P78332-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RBM6: NX_P78332

Explore proteomics data for RBM6 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RBM6 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001161054.1  NP_005768.1  

    ENSEMBL proteins: 
     ENSP00000393530   ENSP00000266022   ENSP00000396466   ENSP00000396410   ENSP00000392939  
     ENSP00000406548   ENSP00000408665   ENSP00000399942   ENSP00000389763   ENSP00000394336  
     ENSP00000403865   ENSP00000392475   ENSP00000443165  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    GPATCH: G patch domain containing
    RBM: RNA binding motif (RRM) containing

    5 InterPro protein domains:
     IPR012677 Nucleotide-bd_a/b_plait
     IPR028806 RBM6
     IPR015880 Znf_C2H2-like
     IPR000467 G_patch_dom
     IPR000504 RRM_dom

    Graphical View of Domain Structure for InterPro Entry P78332

    ProtoNet protein and cluster: P78332

    2 Blocks protein domains:
    IPB000467 D111/G-patch domain
    IPB000504 RNA-binding region RNP-1 (RNA recognition motif)


    UniProtKB/Swiss-Prot: RBM6_HUMAN, P78332
    Similarity: Contains 1 G-patch domain
    Similarity: Contains 1 RRM (RNA recognition motif) domain


    RBM6 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RBM6_HUMAN, P78332
    Function: Specifically binds poly(G) RNA homopolymers in vitro

         Genatlas biochemistry entry for RBM6:
    RNA binding protein 6,including two alternatively spliced long and short (truncated) isoforms with some homology
    with DXS8237E,located in a region duplicated for the Xp11.3-p11.23 region containing UBE1 and DXS8237E

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding TAS10352938
    GO:0003723RNA binding TAS10352938
    GO:0044822poly(A) RNA binding IDA--
         
    RBM6 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RBM6
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    miRNA
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    miRTarBase miRNAs that target RBM6:
    hsa-mir-16-5p (MIRT031440), hsa-let-7a-5p (MIRT052467), hsa-mir-221-3p (MIRT046966)

    Block miRNA regulation of human, mouse, rat RBM6 using miScript Target Protectors
    6 qRT-PCR Assays for microRNAs that regulate RBM6:
    hsa-miR-424 hsa-miR-15a hsa-miR-497 hsa-miR-16 hsa-miR-195 hsa-miR-15b
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBM6


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RBM6_HUMAN, P78332: Nucleus (Probable)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4
    cytosol2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    RBM6 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RBM6
    Interactions:

        Search GeneGlobe Interaction Network for RBM6

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    Selected Interacting proteins for RBM6 (P783323 ENSP000002660224) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FOSP011003I2D: score=1 
    SUMO2ENSP000004059654STRING: ENSP00000405965
    SIRT7ENSP000003294664STRING: ENSP00000329466
    SF3B3ENSP000003057904STRING: ENSP00000305790
    TAF7ENSP000003127094STRING: ENSP00000312709
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006396RNA processing TAS10352938

    RBM6 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RBM6



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for RBM6 gene (2 alternative transcripts): 
    NM_001167582.1  NM_005777.2  

    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 21):
    ENST00000442092 ENST00000266022(uc011bdh.2 uc010hlc.2 uc003cyd.3 uc011bdi.2 uc003cyc.3 uc003cye.3)
    ENST00000443081 ENST00000419610 ENST00000441115 ENST00000493652 ENST00000422955
    ENST00000454079 ENST00000425608 ENST00000434592(uc010hlf.2 uc010hld.2 uc010hle.2)
    ENST00000433811 ENST00000491874 ENST00000488807 ENST00000464013 ENST00000483350
    ENST00000446471 ENST00000466247 ENST00000478026
    miRNA
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    6 qRT-PCR Assays for microRNAs that regulate RBM6:
    hsa-miR-424 hsa-miR-15a hsa-miR-497 hsa-miR-16 hsa-miR-195 hsa-miR-15b
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    GenScript: all cDNA clones in your preferred vector (see all 2): RBM6 (NM_005777)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RBM6
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    OriGene qSTAR qPCR primer pairs in human, mouse for RBM6
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RBM6
      QuantiTect SYBR Green Assays in human, mouse, rat RBM6
      QuantiFast Probe-based Assays in human, mouse, rat RBM6

    Selected AceView cDNA sequences (see all 320):

    AI141574 AW959421 AI125793 AK093836 BM663974 U50839 D45524 BM992099 
    AA344244 BM826657 AA708489 CD364941 BC030057 BU679057 BM710364 BM452238 
    CF137765 BX505805 AA909163 BI822681 BF061042 CD723654 BF872352 BM978955 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for RBM6 (see all 11)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b · 12c ^ 13a · 13b · 13c ^ 14 ^ 15 ^
    SP1:                          -           -     -                                         -           -                                         -               
    SP2:                          -           -     -     -     -                 -     -     -           -                                         -               
    SP3:                          -           -     -     -     -     -     -     -     -     -           -                                         -               
    SP4:                                                                                                  -                                                         
    SP5:                                                                                      -           -                                                         

    ExUns: 16 ^ 17 ^ 18a · 18b ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24
    SP1:              -                                             
    SP2:              -                                             
    SP3:              -                                             
    SP4:                                                            
    SP5:                                                            


    ECgene alternative splicing isoforms for RBM6

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RBM6 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGATACAACC
    RBM6 Expression
    About this image


    RBM6 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 15) fully expand
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Cerebral Cortex
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Ovarian Mesenchymal Stroma Cells Ovary Interstitium
             Oviduct
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
    RBM6 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RBM6 Protein Expression

    UniProtKB/Swiss-Prot: RBM6_HUMAN, P78332
    Tissue specificity: Ubiquitous in adults

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBM6

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for RBM6 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rbm61 , 5 RNA binding motif protein 61, 5 89.86(n)1
    89.45(a)1
      9 (59.07 cM)5
    196541  NM_011251.31  NP_035381.21 
     1077735595 
    chicken
    (Gallus gallus)
    Aves RBM61 RNA binding motif protein 6 68.47(n)
    64.96(a)
      415931  NM_001030588.2  NP_001025759.2 
    lizard
    (Anolis carolinensis)
    Reptilia RBM66
    RNA binding motif protein 6
    52(a)
    1 ↔ 1
    2(148014812-148078382)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia BX685282.12   -- 73.36(n)    BX685282.1 
    zebrafish
    (Danio rerio)
    Actinopterygii rbm66
    RNA binding motif protein 6
    15(a)
    1 ↔ 1
    6(42598104-42622146) ENSDARG00000077060
    fruit fly
    (Drosophila melanogaster)
    Insecta CG48966
    CG48876
    --
    18(a)
    17(a)
    many ↔ many
    many ↔ many
    2L(1177706-1182454)
    2L(1173009-1177589)
    worm
    (Caenorhabditis elegans)
    Secernentea T08B2.56
    Protein T08B2.5, isoform d (T08B2.5) mRNA, complet...
    16(a)
    1 → many
    I(6215669-6219911) WBGene00020346


    ENSEMBL Gene Tree for RBM6 (if available)
    TreeFam Gene Tree for RBM6 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RBM6 gene
    RBM102  RBM52  

    RBM6 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RBM6 (see all 2471)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs617313291,2,,4
    C,FA non-small cell lung cancer cell line4 --50005916(+) TGAGTC/TTCCAG 3 S F int1 mis14Minor allele frequency- T:0.01NS NA EU 6067
    rs1930991591,2
    C--49975492(+) TCTGTC/TGCCCA 2 -- us2k10--------
    rs76099711,2
    C,F,A--49975654(+) tttcaT/Ccgtgt 2 -- us2k16Minor allele frequency- C:0.42NA WA 12
    rs1849660901,2
    --49975734(+) CAAGCA/GTGAGC 2 -- us2k10--------
    rs1885991591,2
    --49975799(+) TGAGGC/TTGGAG 2 -- us2k10--------
    rs1915697421,2
    --49975808(+) AGTGCA/GGTGGC 2 -- us2k10--------
    rs1838622371,2
    --49976039(+) GGCACG/TGCGCC 2 -- us2k10--------
    rs1387094221,2
    --49976045(+) GCGCCC/TGGCCT 2 -- us2k10--------
    rs2005372861,2
    C--49976145(+) CTGCC-/CCCGGG 2 -- us2k10--------
    rs760087961,2
    C,F--49976238(+) TTTTGA/CGACAG 2 -- us2k11Minor allele frequency- C:0.00NA 2

    HapMap Linkage Disequilibrium report for RBM6 (49977440 - 50137478 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for RBM6 (see all 11):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2725257CNV Deletion23290073
    esv1004636CNV Deletion20482838
    esv2659342CNV Deletion23128226
    esv1163072CNV Insertion17803354
    nsv822078CNV Loss20364138
    nsv820223CNV Loss19587683
    nsv834688CNV Loss17160897
    nsv876767CNV Loss21882294
    nsv515986CNV Loss19592680
    nsv834690CNV Loss17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606886    OMIM disorders: --

    11 diseases for RBM6:    
    About MalaCards
    chronic cystitis    lung cancer    cystitis    megakaryocytic leukemia
    bladder carcinoma    tonsillitis    leukemia    thyroiditis
    cerebritis    endotheliitis    prostatitis


    RBM6 for disorders           About GeneDecksing

    Genetic Association Database (GAD): RBM6
    Human Genome Epidemiology (HuGE) Navigator: RBM6 (1 document)

    Export disorders for RBM6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RBM6 gene, integrated from 10 sources (see all 29):
    (articles sorted by number of sources associating them with RBM6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A comparison of genomic structures and expression patterns of two closely related flanking genes in a critical lung cancer region at 3p21.3. (PubMed id 10352938)1, 2, 3 Timmer T.... Buys C.H.C.M. (Eur. J. Hum. Genet. 1999)
    2. Human lung cancer antigens recognized by autologous antibodies: definition of a novel cDNA derived from the tumor suppressor gene locus on chromosome 3p21.3. (PubMed id 9500467)1, 2, 9 Gure A.O....Chen Y.-T. (Cancer Res. 1998)
    3. Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. (PubMed id 21102462)1, 4 Elks C.E....Murray A. (Nat. Genet. 2010)
    4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    5. The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. (PubMed id 11085536)1, 2 Lerman M.I. and Minna J.D. (Cancer Res. 2000)
    6. DEF-3(g16/NY-LU-12), an RNA binding protein from the 3p21.3 homozygous deletion region in SCLC. (PubMed id 10353602)1, 2 Drabkin H.A.... Sablitzky F. (Oncogene 1999)
    7. RBM6-RBM5 transcription-induced chimeras are differentially expressed in tumours. (PubMed id 17908320)1, 9 Wang K....Sutherland L.C. (BMC Genomics 2007)
    8. Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C.... Cristea I.M. (Mol. Cell. Proteomics 2012)
    9. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    10. The novel protein MANI modulates neurogenesis and neurite-cone growth. (PubMed id 20716133)2 Mishra M.... Heese K. (J. Cell. Mol. Med. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10180 HGNC: 9903 AceView: RBM6 Ensembl:ENSG00000004534 euGenes: HUgn10180
    ECgene: RBM6 H-InvDB: RBM6

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RBM6 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RBM6 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RBM6 gene:
    Search GeneIP for patents involving RBM6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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