RBM47 Gene
protein-coding GIFtS : 49
GCID: GC04 M040425
RNA binding motif protein 47
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Aliasesfor RBM47 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases RNA Binding Motif Protein 47 1 2 NET181 2 RNA-Binding Motif Protein 472 3 FLJ202731 RNA-Binding Protein 472
Export aliases for RBM47 gene to outside databases Previous GC identifers: GC04M040121 GC04M039747
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Summariesfor RBM47 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section --
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Genomic Viewsfor RBM47 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000004.11 NC_018915.1 NT_006238.11 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the RBM47 gene promoter: STAT5B HOXA3 GATA-3 IRF-1 NF-kappaB C/EBPalpha S8 Ik-2 NF-kappaB2 NF-kappaB1 Other transcription factors Search SABiosciences Chromatin IP Primers for RBM47 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat RBM47
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 4p14 Ensembl cytogenetic band: 4p14 HGNC cytogenetic band: 4p14 RBM47 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 4 GeneLoc Exon Structure
GeneLoc location for GC04M040425: view genomic region
(about GC identifiers )
Start:
40,425,272 bp from pter
End:
40,632,892 bp from pter
Size:
207,621 bases
Orientation:
minus strand
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Proteinsfor RBM47 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: RBM47_HUMAN, A0AV96 (See
protein sequence )Recommended Name: RNA-binding protein 47 Size : 593 amino acids; 64099 Da
Subcellular location : Nucleus (By similarity)
Sequence caution : Sequence=AAM21973.1; Type=Frameshift; Positions=561, 577;
1 PDB 3D structure from and Proteopedia for RBM47 :2DIS (3D)
 
Secondary accessions : A0PJK2 B5MED4 Q8NI52 Q8NI53 Q9NXG3Alternative splicing : 2 isoforms : A0AV96-1 A0AV96-2 Explore the universe of human proteins at neXtProt for RBM47: NX_A0AV96 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_A0AV96 RBM47 Protein expression data from MOPED and PaxDb : About this image REFSEQ proteins (2 alternative transcripts):
NP_001092104.1 NP_061900.2 ENSEMBL proteins: ENSP00000371212 ENSP00000371214 ENSP00000422945 ENSP00000295971 ENSP00000423243 ENSP00000422564 ENSP00000421589 ENSP00000423527 ENSP00000426542 ENSP00000423398 ENSP00000424019 ENSP00000425111 ENSP00000425507 ENSP00000320108 Human Recombinant Protein Products for RBM47: Gene Ontology (GO): 1 cellular component term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0005634 nucleus
IEA --
RBM47 for ontologies About GeneDecksing RBM47 Antibody Products: Assay Products for RBM47:
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Protein
Domains / Familiesfor RBM47 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
RBM47 for domains About GeneDecksing 3 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry A0AV96 ProtoNet protein and cluster: A0AV96
UniProtKB/Swiss-Prot: RBM47_HUMAN, A0AV96 Similarity : Belongs to the RRM RBM47 familySimilarity : Contains 3 RRM (RNA recognition motif) domains
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Functionfor RBM47 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view) : About this table
RBM47 for ontologies About GeneDecksing Phenotypes: 3 GenomeRNAi human phenotypes for RBM47 :Animal Models: Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for RBM47 (see all 6 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for RBM47 (see all 2 )OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 2 ): RBM47 (NM_019027 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RBM47 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat RBM47
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBM47
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Pathways & Interactionsfor RBM47 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RBM47 STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)2 Interacting proteins for RBM47 (A0AV96 3 ENSP00000295971 4 ) via UniProtKB, MINT, STRING , and/or I2D About this table
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Drugs & Compoundsfor RBM47 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for RBM47 Search CenterWatch for drugs/clinical trials and news about RBM47
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Transcriptsfor RBM47 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for RBM47 gene (2 alternative transcripts): NM_001098634.1 NM_019027.3 Unigene Cluster for RBM47:
RNA binding motif protein 47 Hs.518727 [show with all ESTs ] Unigene Representative Sequence: NM_001098634 16 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000381793 (uc011bys.1 uc003gvg.1 ) ENST00000381795 (uc003gvd.2 )ENST00000510871 (uc003gve.2 ) ENST00000295971 ENST00000514014 ENST00000515809 ENST00000515053 ENST00000513473 ENST00000505414 ENST00000514782 ENST00000507180 ENST00000511598 ENST00000511902 ENST00000505220 ENST00000513044 ENST00000319592 (uc003gvc.2 )Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for RBM47 (see all 6 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for RBM47 (see all 2 )OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 2 ): RBM47 (NM_019027 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RBM47 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat RBM47
Additional cDNA sequence: AF262323.1 AK000280.1 AK024997.1 AK025296.1 AK057152.1 AK304206.1 BC034402.1 BC071585.1 BC126261.1 BC143942.1 BX648404.1
24/27 DOTS entries (see all 27 ): DT.95179861 DT.97856620
DT.95218575 DT.91988839 DT.95218565 DT.95218570 DT.100824950 DT.92442257 DT.95218580 DT.91869700 DT.100824951 DT.114259 DT.91800752 DT.121243423 DT.95218547 DT.100700570 DT.100777775 DT.121243362 DT.92442251 DT.100032000 DT.100699418 DT.102838104 DT.92059811 DT.92442254 24/226 AceView cDNA sequences (see all 226 ):
AA443632 AI245339 AA314230 AA902893 AK024997 BM926694 BX479449 BM768524 AI283858 BM718305 BU741899 BQ924897 AA410964 BE326599 AI800233 AI367914 AI796563 BE536935 CB990408 AA886302 AI261199 AW070545 BF445303 BG697972 GeneLoc Exon Structure 5/6 Alternative Splicing Database (ASD) splice patterns (SP) for RBM47 (see all 6 ) About this scheme ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b ^ 9 SP1 :   -   -     -           -   -     SP2 :         -                 SP3 :     -     -                 SP4 :         -                 SP5 :                        
ECgene alternative splicing isoforms for RBM47
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Expression for RBM47 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section RBM47 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: TACACTACTGAbout this image RBM47 expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table
See RBM47 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for RBM47 SOURCE GeneReport for Unigene cluster: Hs.518727 SABiosciences Custom PCR Arrays for RBM47 Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for RBM47Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat RBM47 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat RBM47 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat RBM47 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBM47
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Orthologsfor RBM47 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of eukaryotes.
Orthologs for RBM47 gene from 6/22 species (see all 22 ) About this table
ENSEMBL Gene Tree for RBM47 (if available)TreeFam Gene Tree for RBM47 (if available)
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Paralogsfor RBM47 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for RBM47 gene SYNCRIP 2 DND1 2 RBM46 2 A1CF 2 HNRNPR 2 9 SIMAP similar genes for RBM47 using alignment to 11 protein entries: RBM47_HUMAN (see all proteins ):RBM46 A1CF SYNCRIP CELF3 DND1 HNRPR DKFZp686A13234 HNRNPR RBMY1A1
RBM47 for paralogs About GeneDecksing
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Genomic Variantsfor RBM47 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 4 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for RBM47 (40425272 - 40632892 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 3 variations for RBM47 3 CNVs : 32598 3492 32597
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing RBM47
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Disorders
/ Diseasesfor RBM47 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
RBM47 for disorders About GeneDecksing 2 diseases for RBM47 : About MalaCards intrahepatic cholangiocarcinoma cholangiocarcinoma Human Genome Epidemiology (HuGE) Navigator: RBM47 (2 documents) Export disorders for RBM47 gene to outside databases
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Publicationsfor RBM47 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for RBM47 gene, integrated from 9 sources (see all 12 ): (articles sorted by number of sources associating them with RBM47) Utopia : connect your pdf to the dynamic world of online information
A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473) 1 Wagner S.A....Choudhary C. (2011) Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614) 1 Rose J.E....Uhl G.R. (2010) Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201) 1 Abdelmohsen K....Gorospe M. (2009) Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. (PubMed id 16712791) 1 Wang A.G....Kim N.S. (2006) Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560) 1 Kimura K.... Sugano S. (2006) Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621) 2 Hillier L.W....Wilson R.K. (2005) Transcriptome analysis of human gastric cancer. (PubMed id 16341674) 1 Oh J.H....Kim N.S. (2005) Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556) 1 Suzuki Y.... Sugano S. (2004) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 2 Gerhard D.S....Malek J. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 2 Ota T.... Sugano S. (2004)
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External Searches for RBM47 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing RBM47 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing RBM47 gene
(According to HUGE )
About This Section --
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Specialized Databases showing RBM47 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for RBM47 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for RBM47 gene: Search GeneIP for patents involving RBM47 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor RBM47 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
Browse OriGene Antibodies OriGene shRNA RFP for RBM47 OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for RBM47 OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for RBM47 OriGene Protein Over-expression Lysate for RBM47 Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for RBM47 OriGene 3'-UTR Clone for RBM47 OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for RBM47 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for RBM47 Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs OriGene Purified Protein for RBM47 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RBM47 QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing RBM47 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat RBM47 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat RBM47 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat RBM47 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat RBM47
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RBM47 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBM47
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Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat RBM47
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