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Aliases for RBM46 Gene

Aliases for RBM46 Gene

  • RNA Binding Motif Protein 46 2 3
  • Cancer/Testis Antigen 68 2 3 4
  • RNA-Binding Motif Protein 46 3 4
  • CT68 3 4
  • Probable RNA-Binding Protein 46 3

External Ids for RBM46 Gene

Summaries for RBM46 Gene

GeneCards Summary for RBM46 Gene

RBM46 (RNA Binding Motif Protein 46) is a Protein Coding gene. GO annotations related to this gene include RNA binding and nucleotide binding. An important paralog of this gene is HNRNPR.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RBM46 Gene

Genomics for RBM46 Gene

Genomic Location for RBM46 Gene

Start:
154,781,213 bp from pter
End:
154,828,813 bp from pter
Size:
47,601 bases
Orientation:
Plus strand

Genomic View for RBM46 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RBM46 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RBM46 Gene

Regulatory Elements for RBM46 Gene

Proteins for RBM46 Gene

  • Protein details for RBM46 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TBY0-RBM46_HUMAN
    Recommended name:
    Probable RNA-binding protein 46
    Protein Accession:
    Q8TBY0
    Secondary Accessions:
    • B3KWU8
    • B4DZ27

    Protein attributes for RBM46 Gene

    Size:
    533 amino acids
    Molecular mass:
    60023 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for RBM46 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for RBM46 Gene

Proteomics data for RBM46 Gene at MOPED

Post-translational modifications for RBM46 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RBM46 Gene

No data available for DME Specific Peptides for RBM46 Gene

Domains for RBM46 Gene

Gene Families for RBM46 Gene

HGNC:
  • RBM :RNA binding motif (RRM) containing

UniProtKB/Swiss-Prot:

RBM46_HUMAN
Domain:
  • Contains 3 RRM (RNA recognition motif) domains.:
    • Q8TBY0
genes like me logo Genes that share domains with RBM46: view

Function for RBM46 Gene

Gene Ontology (GO) - Molecular Function for RBM46 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0003676 nucleic acid binding --
GO:0003723 RNA binding IEA --
genes like me logo Genes that share ontologies with RBM46: view

miRNA for RBM46 Gene

miRTarBase miRNAs that target RBM46

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for RBM46 Gene

Localization for RBM46 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RBM46 Gene COMPARTMENTS Subcellular localization image for RBM46 gene
Compartment Confidence
nucleus 3
cytosol 1
peroxisome 1

No data available for Gene Ontology (GO) - Cellular Components for RBM46 Gene

Pathways for RBM46 Gene

SuperPathways for RBM46 Gene

No Data Available

Interacting Proteins for RBM46 Gene

Gene Ontology (GO) - Biological Process for RBM46 Gene

None

No data available for Pathways by source for RBM46 Gene

Transcripts for RBM46 Gene

Unigene Clusters for RBM46 Gene

RNA binding motif protein 46:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RBM46 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9
SP1: - - - -
SP2: - -
SP3:
SP4:

Relevant External Links for RBM46 Gene

GeneLoc Exon Structure for
RBM46
ECgene alternative splicing isoforms for
RBM46

Expression for RBM46 Gene

mRNA expression in normal human tissues for RBM46 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for RBM46 Gene

This gene is overexpressed in Testis (43.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for RBM46 Gene

SOURCE GeneReport for Unigene cluster for RBM46 Gene Hs.133095

genes like me logo Genes that share expressions with RBM46: view

Orthologs for RBM46 Gene

This gene was present in the common ancestor of animals.

Orthologs for RBM46 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia RBM46 36
  • 99.5 (n)
  • 99.62 (a)
RBM46 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia RBM46 36
  • 94.5 (n)
  • 97 (a)
RBM46 37
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia RBM46 36
  • 95.62 (n)
  • 98.5 (a)
RBM46 37
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Rbm46 36
  • 90.46 (n)
  • 97.44 (a)
Rbm46 16
Rbm46 37
  • 96 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia RBM46 37
  • 89 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia RBM46 37
  • 88 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Rbm46 36
  • 91.62 (n)
  • 97.37 (a)
chicken
(Gallus gallus)
Aves RBM46 36
  • 79.13 (n)
  • 79.91 (a)
RBM46 37
  • 79 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia RBM46 37
  • 92 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100498620 36
  • 75.27 (n)
  • 75.14 (a)
Str.19533 36
zebrafish
(Danio rerio)
Actinopterygii rbm46 36
  • 64.06 (n)
  • 67.94 (a)
rbm46 37
  • 63 (a)
OneToOne
wufe11d09 36
fruit fly
(Drosophila melanogaster)
Insecta CG17838 37
  • 25 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea hrp-2 37
  • 26 (a)
OneToMany
Species with no ortholog for RBM46:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RBM46 Gene

ENSEMBL:
Gene Tree for RBM46 (if available)
TreeFam:
Gene Tree for RBM46 (if available)

Paralogs for RBM46 Gene

Paralogs for RBM46 Gene

Selected SIMAP similar genes for RBM46 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with RBM46: view

Variants for RBM46 Gene

Sequence variations from dbSNP and Humsavar for RBM46 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type MAF
rs156502 -- 154,799,122(-) TGACC(A/G)TTAAG synonymous-codon, reference
rs156503 -- 154,797,935(-) ATCAT(A/C)AGTCG synonymous-codon, reference
rs156513 -- 154,790,709(-) ATAAA(C/T)AGAAA intron-variant
rs156514 -- 154,789,903(-) accct(C/T)ccaag intron-variant
rs156515 -- 154,788,649(-) gacaa(A/T)cctaa intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RBM46 Gene

Variant ID Type Subtype PubMed ID
nsv820098 CNV Gain 19587683

Relevant External Links for RBM46 Gene

HapMap Linkage Disequilibrium report
RBM46

Disorders for RBM46 Gene

Relevant External Links for RBM46

Genetic Association Database (GAD)
RBM46
genes like me logo Genes that share disorders with RBM46: view

No data available for UniProtKB/Swiss-Prot for RBM46 Gene

Publications for RBM46 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study. (PMID: 17903292) Hwang S.J. … Fox C.S. (BMC Med. Genet. 2007) 49
  4. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PMID: 17903299) Kathiresan S. … Cupples L.A. (BMC Med. Genet. 2007) 49
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4

Products for RBM46 Gene

Sources for RBM46 Gene

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