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Aliases for RBM44 Gene

Aliases for RBM44 Gene

  • RNA Binding Motif Protein 44 2 3
  • RNA-Binding Motif Protein 44 4

External Ids for RBM44 Gene

Previous GeneCards Identifiers for RBM44 Gene

  • GC02P238373
  • GC02P238707
  • GC02P230499

Summaries for RBM44 Gene

GeneCards Summary for RBM44 Gene

RBM44 (RNA Binding Motif Protein 44) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and RNA binding.

UniProtKB/Swiss-Prot for RBM44 Gene

  • Component of intercellular bridges during meiosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells. Not required for fertility (By similarity).

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RBM44 Gene

Genomics for RBM44 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for RBM44 Gene

Chromosome:
2
Start:
237,798,050 bp from pter
End:
237,842,808 bp from pter
Size:
44,759 bases
Orientation:
Plus strand

Genomic View for RBM44 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RBM44 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RBM44 Gene

Proteins for RBM44 Gene

  • Protein details for RBM44 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZP01-RBM44_HUMAN
    Recommended name:
    RNA-binding protein 44
    Protein Accession:
    Q6ZP01
    Secondary Accessions:
    • A0AUW3

    Protein attributes for RBM44 Gene

    Size:
    1051 amino acids
    Molecular mass:
    117985 Da
    Quaternary structure:
    • Homodimer. Interacts with TEX14 (By similarity).
    SequenceCaution:
    • Sequence=AAI26112.1; Type=Miscellaneous discrepancy; Note=Unlikely splicing event.; Evidence={ECO:0000305}; Sequence=BAC85324.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for RBM44 Gene

Proteomics data for RBM44 Gene at MOPED

Post-translational modifications for RBM44 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RBM44 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RBM44 Gene

Domains & Families for RBM44 Gene

Gene Families for RBM44 Gene

Protein Domains for RBM44 Gene

Suggested Antigen Peptide Sequences for RBM44 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6ZP01

UniProtKB/Swiss-Prot:

RBM44_HUMAN :
  • Contains 1 RRM (RNA recognition motif) domain.
Domain:
  • Contains 1 RRM (RNA recognition motif) domain.
genes like me logo Genes that share domains with RBM44: view

Function for RBM44 Gene

Molecular function for RBM44 Gene

UniProtKB/Swiss-Prot Function:
Component of intercellular bridges during meiosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells. Not required for fertility (By similarity).

Gene Ontology (GO) - Molecular Function for RBM44 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0003676 nucleic acid binding --
GO:0003723 RNA binding IEA --
GO:0005515 protein binding --
GO:0042803 protein homodimerization activity ISS --
genes like me logo Genes that share ontologies with RBM44: view

Phenotypes for RBM44 Gene

genes like me logo Genes that share phenotypes with RBM44: view

Animal Models for RBM44 Gene

MGI Knock Outs for RBM44:

Animal Model Products

CRISPR Products

miRNA for RBM44 Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RBM44

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for RBM44 Gene

Localization for RBM44 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RBM44 Gene

Cytoplasm. Note=Detected in the intercellular bridges. {ECO:0000250}.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RBM44 Gene COMPARTMENTS Subcellular localization image for RBM44 gene
Compartment Confidence
extracellular 4

Gene Ontology (GO) - Cellular Components for RBM44 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm ISS --
GO:0045171 intercellular bridge ISS --
genes like me logo Genes that share ontologies with RBM44: view

Pathways & Interactions for RBM44 Gene

SuperPathways for RBM44 Gene

No Data Available

Interacting Proteins for RBM44 Gene

Gene Ontology (GO) - Biological Process for RBM44 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RBM44 Gene

Drugs & Compounds for RBM44 Gene

No Compound Related Data Available

Transcripts for RBM44 Gene

Unigene Clusters for RBM44 Gene

RNA binding motif protein 44:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RBM44

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RBM44 Gene

No ASD Table

Relevant External Links for RBM44 Gene

GeneLoc Exon Structure for
RBM44
ECgene alternative splicing isoforms for
RBM44

Expression for RBM44 Gene

mRNA expression in normal human tissues for RBM44 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for RBM44 Gene

This gene is overexpressed in Testis (x16.8).

Protein differential expression in normal tissues from HIPED for RBM44 Gene

This gene is overexpressed in Ovary (35.2) and Testis (32.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for RBM44 Gene



SOURCE GeneReport for Unigene cluster for RBM44 Gene Hs.720233

genes like me logo Genes that share expression patterns with RBM44: view

Protein tissue co-expression partners for RBM44 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for RBM44 Gene

Orthologs for RBM44 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RBM44 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia RBM44 35
  • 84.23 (n)
  • 72.61 (a)
RBM44 36
  • 72 (a)
OneToOne
dog
(Canis familiaris)
Mammalia RBM44 35
  • 84.23 (n)
  • 72.51 (a)
RBM44 36
  • 71 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Rbm44 35
  • 72.82 (n)
  • 57.84 (a)
Rbm44 16
Rbm44 36
  • 57 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia RBM44 35
  • 98.61 (n)
  • 97.34 (a)
RBM44 36
  • 97 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Rbm44 35
  • 71.32 (n)
  • 57.17 (a)
oppossum
(Monodelphis domestica)
Mammalia RBM44 36
  • 39 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia RBM44 36
  • 42 (a)
OneToOne
chicken
(Gallus gallus)
Aves RBM44 36
  • 37 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 35 (a)
OneToMany
-- 36
  • 39 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii RBM44 36
  • 19 (a)
OneToOne
Species with no ortholog for RBM44:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RBM44 Gene

ENSEMBL:
Gene Tree for RBM44 (if available)
TreeFam:
Gene Tree for RBM44 (if available)

Paralogs for RBM44 Gene

No data available for Paralogs for RBM44 Gene

Variants for RBM44 Gene

Sequence variations from dbSNP and Humsavar for RBM44 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs919973 -- 237,829,745(+) TGCCA(A/G)TCTTT intron-variant
rs919974 -- 237,829,845(+) AAACC(A/G)TAAAA intron-variant
rs919975 -- 237,829,996(+) ATTTT(A/T)AAAAA intron-variant
rs1000635 -- 237,826,472(+) TCTCC(C/T)CTTTT intron-variant
rs1000636 -- 237,826,693(+) ACAAA(G/T)Acaat intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RBM44 Gene

Variant ID Type Subtype PubMed ID
nsv519581 CNV Loss 19592680
nsv516443 CNV Gain+Loss 19592680
esv268050 CNV Insertion 20981092
esv2678433 CNV Deletion 23128226

Variation tolerance for RBM44 Gene

Residual Variation Intolerance Score: 61.16% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.67; 65.84% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RBM44 Gene

HapMap Linkage Disequilibrium report
RBM44

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RBM44 Gene

Disorders for RBM44 Gene

Relevant External Links for RBM44

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
RBM44
genes like me logo Genes that share disorders with RBM44: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RBM44 Gene

Publications for RBM44 Gene

  1. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 67
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 67
  3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 67
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67

Products for RBM44 Gene

Sources for RBM44 Gene

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