Free for academic non-profit institutions. Other users need a Commercial license

Aliases for RBM43 Gene

Aliases for RBM43 Gene

  • RNA Binding Motif Protein 43 2 3 5
  • RNA-Binding Motif Protein 43 3 4
  • C2orf38 3 4
  • Chromosome 2 Open Reading Frame 38 2

External Ids for RBM43 Gene

Previous HGNC Symbols for RBM43 Gene

  • C2orf38

Previous GeneCards Identifiers for RBM43 Gene

  • GC02M151815
  • GC02M152104
  • GC02M144001

Summaries for RBM43 Gene

GeneCards Summary for RBM43 Gene

RBM43 (RNA Binding Motif Protein 43) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and nucleotide binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RBM43 Gene

Genomics for RBM43 Gene

Regulatory Elements for RBM43 Gene

Enhancers for RBM43 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around RBM43 on UCSC Golden Path with GeneCards custom track

Promoters for RBM43 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around RBM43 on UCSC Golden Path with GeneCards custom track

Genomic Location for RBM43 Gene

Chromosome:
2
Start:
151,247,940 bp from pter
End:
151,261,901 bp from pter
Size:
13,962 bases
Orientation:
Minus strand

Genomic View for RBM43 Gene

Genes around RBM43 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RBM43 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RBM43 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RBM43 Gene

Proteins for RBM43 Gene

  • Protein details for RBM43 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZSC3-RBM43_HUMAN
    Recommended name:
    RNA-binding protein 43
    Protein Accession:
    Q6ZSC3
    Secondary Accessions:
    • B2RMT5

    Protein attributes for RBM43 Gene

    Size:
    357 amino acids
    Molecular mass:
    40666 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RBM43 Gene

Proteomics data for RBM43 Gene at MOPED

Post-translational modifications for RBM43 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RBM43 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RBM43 Gene

Domains & Families for RBM43 Gene

Gene Families for RBM43 Gene

Protein Domains for RBM43 Gene

Suggested Antigen Peptide Sequences for RBM43 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6ZSC3

UniProtKB/Swiss-Prot:

RBM43_HUMAN :
  • Contains 1 RRM (RNA recognition motif) domain.
Domain:
  • Contains 1 RRM (RNA recognition motif) domain.
genes like me logo Genes that share domains with RBM43: view

Function for RBM43 Gene

Gene Ontology (GO) - Molecular Function for RBM43 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0003723 RNA binding IEA --
genes like me logo Genes that share ontologies with RBM43: view
genes like me logo Genes that share phenotypes with RBM43: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RBM43 Gene

Localization for RBM43 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RBM43 Gene COMPARTMENTS Subcellular localization image for RBM43 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for RBM43 Gene

Pathways & Interactions for RBM43 Gene

SuperPathways for RBM43 Gene

No Data Available

Gene Ontology (GO) - Biological Process for RBM43 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RBM43 Gene

Drugs & Compounds for RBM43 Gene

No Compound Related Data Available

Transcripts for RBM43 Gene

mRNA/cDNA for RBM43 Gene

(2) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(15) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RBM43 Gene

RNA binding motif protein 43:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RBM43 Gene

No ASD Table

Relevant External Links for RBM43 Gene

GeneLoc Exon Structure for
RBM43
ECgene alternative splicing isoforms for
RBM43

Expression for RBM43 Gene

mRNA expression in normal human tissues for RBM43 Gene

Protein differential expression in normal tissues from HIPED for RBM43 Gene

This gene is overexpressed in Lung (47.4) and Esophagus (15.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for RBM43 Gene



SOURCE GeneReport for Unigene cluster for RBM43 Gene Hs.302442

genes like me logo Genes that share expression patterns with RBM43: view

Protein tissue co-expression partners for RBM43 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RBM43 Gene

Orthologs for RBM43 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RBM43 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia RBM43 35
  • 80.02 (n)
  • 66.37 (a)
RBM43 36
  • 66 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Rbm43 35
  • 72.11 (n)
  • 58.02 (a)
Rbm43 16
Rbm43 36
  • 58 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia RBM43 35
  • 99.34 (n)
  • 99.15 (a)
RBM43 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Rbm43 35
  • 71.82 (n)
  • 59.48 (a)
dog
(Canis familiaris)
Mammalia RBM43 36
  • 61 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia RBM43 36
  • 44 (a)
OneToOne
chicken
(Gallus gallus)
Aves RBM43 35
  • 55.39 (n)
  • 39.47 (a)
RBM43 36
  • 36 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia RBM43 36
  • 29 (a)
OneToOne
Species with no ortholog for RBM43:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RBM43 Gene

ENSEMBL:
Gene Tree for RBM43 (if available)
TreeFam:
Gene Tree for RBM43 (if available)

Paralogs for RBM43 Gene

Pseudogenes.org Pseudogenes for RBM43 Gene

genes like me logo Genes that share paralogs with RBM43: view

No data available for Paralogs for RBM43 Gene

Variants for RBM43 Gene

Sequence variations from dbSNP and Humsavar for RBM43 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs35749426 - 151,251,205(-) CCACA(A/G)TTTGT reference, missense
rs403411 -- 151,260,109(-) GGGGG(A/G)GCGGA intron-variant
rs414488 -- 151,260,608(-) AGTTC(A/T)TACCA intron-variant
rs2880488 -- 151,258,384(+) TACTT(C/T)AAAAA intron-variant
rs2880489 -- 151,258,908(+) gagga(G/T)gaggc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RBM43 Gene

Variant ID Type Subtype PubMed ID
esv34659 CNV Loss 17911159
nsv523849 CNV Gain 19592680
nsv834417 CNV Gain 17160897

Variation tolerance for RBM43 Gene

Residual Variation Intolerance Score: 86.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.82; 34.25% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RBM43 Gene

Human Gene Mutation Database (HGMD)
RBM43

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RBM43 Gene

Disorders for RBM43 Gene

Relevant External Links for RBM43

Genetic Association Database (GAD)
RBM43
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
RBM43

No disorders were found for RBM43 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RBM43 Gene

Publications for RBM43 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. Genome-wide association study link novel loci to endometriosis. (PMID: 23472165) Albertsen H.M. … Ward K. (PLoS ONE 2013) 3
  3. A genome-wide association search for type 2 diabetes genes in African Americans. (PMID: 22238593) Palmer N.D. … Sladek R. (PLoS ONE 2012) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for RBM43 Gene

Sources for RBM43 Gene

Content