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RBM41 Gene

protein-coding   GIFtS: 49
GCID: GC0XM106307

RNA Binding Motif Protein 41

  See RBM41-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RNA Binding Motif Protein 411 2
RNA-Binding Motif Protein 412 3
RNA-Binding Protein 412

External Ids:    HGNC: 256171   Entrez Gene: 552852   Ensembl: ENSG000000896827   UniProtKB: Q96IZ53   

Export aliases for RBM41 gene to outside databases

Previous GC identifers: GC0XM106194 GC0XM095932


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RBM41 Gene:
RBM41 (RNA binding motif protein 41) is a protein-coding gene. Diseases associated with RBM41 include ebstein anomaly. GO annotations related to this gene include RNA binding and nucleotide binding. An important paralog of this gene is RNPC3.

UniProtKB/Swiss-Prot: RBM41_HUMAN, Q96IZ5
Function: May bind RNA (Potential)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000023.10  NT_011651.18  NC_018934.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RBM41 gene promoter:
         FOXF2   AML1a   Nkx2-5   Evi-1   C/EBPalpha   Ik-2   FOXJ2 (long isoform)   FOXO1a   FOXJ2   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRBM41 promoter sequence
   Search Chromatin IP Primers for RBM41

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RBM41


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq22.3   Ensembl cytogenetic band:  Xq22.3   HGNC cytogenetic band: Xq22.3

RBM41 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RBM41 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM106307:  view genomic region     (about GC identifiers)

Start:
106,305,115 bp from pter      End:
106,362,057 bp from pter
Size:
56,943 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: RBM41_HUMAN, Q96IZ5 (See protein sequence)
Recommended Name: RNA-binding protein 41  
Size: 413 amino acids; 47100 Da
1 PDB 3D structure from and Proteopedia for RBM41:
2CPX (3D)    
Secondary accessions: Q5JSN7 Q5JSN8 Q9H8F7 Q9NV04
Alternative splicing: 3 isoforms:  Q96IZ5-1   Q96IZ5-2   Q96IZ5-3   

Explore the universe of human proteins at neXtProt for RBM41: NX_Q96IZ5

Explore proteomics data for RBM41 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RBM41 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001164551.1  NP_060771.3  

    ENSEMBL proteins: 
     ENSP00000361565   ENSP00000433251   ENSP00000361557   ENSP00000405522   ENSP00000203616  

    RBM41 Human Recombinant Protein Products:

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    Novus Biologicals RBM41 Lysates
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    Cloud-Clone Corp. Proteins for RBM41

     
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    antibodies-online proteins for RBM41 (4 products) 

     
    antibodies-online peptides for RBM41

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    ThermoFisher Antibodies for RBM41
    antibodies-online antibodies for RBM41 (15 products) 

    RBM41 Assay Products:

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    Cloud-Clone Corp. ELISAs for RBM41
    Cloud-Clone Corp. CLIAs for RBM41
    Search eBioscience for ELISAs for RBM41 
    antibodies-online kits for RBM41 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RBM: RNA binding motif (RRM) containing

    2 InterPro protein domains:
     IPR012677 Nucleotide-bd_a/b_plait
     IPR000504 RRM_dom

    Graphical View of Domain Structure for InterPro Entry Q96IZ5

    ProtoNet protein and cluster: Q96IZ5

    1 Blocks protein domain: IPB000504 RNA-binding region RNP-1 (RNA recognition motif)

    UniProtKB/Swiss-Prot: RBM41_HUMAN, Q96IZ5
    Similarity: Contains 1 RRM (RNA recognition motif) domain


    Find genes that share domains with RBM41           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RBM41_HUMAN, Q96IZ5
    Function: May bind RNA (Potential)

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding IEA--
         
    Find genes that share ontologies with RBM41           About GenesLikeMe


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Rbm41):
     normal 

    Find genes that share phenotypes with RBM41           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for RBM41

    miRNA
    Products:
        
    miRTarBase miRNAs that target RBM41:
    hsa-mir-26b-5p (MIRT029092)

    Block miRNA regulation of human, mouse, rat RBM41 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RBM41 (see all 31):
    hsa-miR-345 hsa-miR-495 hsa-miR-376b hsa-miR-4328 hsa-miR-137 hsa-miR-4251 hsa-miR-539 hsa-miR-767-5p
    SwitchGear 3'UTR luciferase reporter plasmidRBM41 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Predesigned siRNA for gene silencing in human, mouse, rat RBM41

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    Sino Biological Human cDNA Clone for RBM41
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RBM41

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    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBM41


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RBM41
    Interactions:

        Search GeneGlobe Interaction Network for RBM41

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RBM41 (Q96IZ52, 3 ENSP000003615574) via UniProtKB, MINT, STRING, and/or I2D (see all 50)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCDC85BQ158342, 3, ENSP000003116954MINT-67091 I2D: score=4 STRING: ENSP00000311695
    RALYLQ86SE52, 3MINT-68256 I2D: score=3 
    HNRNPCP079102, 3, ENSP000003196904MINT-66691 I2D: score=5 STRING: ENSP00000319690
    HNRNPKP619783, ENSP000003654394I2D: score=3 STRING: ENSP00000365439
    GABPB1Q065473I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RBM41



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RBM41 gene (2 alternative transcripts): 
    NM_001171080.1  NM_018301.3  

    Unigene Cluster for RBM41:

    RNA binding motif protein 41
    Hs.139053  [show with all ESTs]
    Unigene Representative Sequence: NM_001171080
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000372487(uc004emy.2) ENST00000495517(uc004emz.3) ENST00000474499
    ENST00000372479 ENST00000434854 ENST00000475556 ENST00000485676 ENST00000471079
    ENST00000203616
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat RBM41 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RBM41 (see all 31):
    hsa-miR-345 hsa-miR-495 hsa-miR-376b hsa-miR-4328 hsa-miR-137 hsa-miR-4251 hsa-miR-539 hsa-miR-767-5p
    SwitchGear 3'UTR luciferase reporter plasmidRBM41 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for RBM41
    Predesigned siRNA for gene silencing in human, mouse, rat RBM41
    Clone
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    OriGene ORF clones in mouse, rat for RBM41
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    GenScript: all cDNA clones in your preferred vector (see all 2): RBM41 (NM_018301)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RBM41
    Primer
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    OriGene qPCR primer pairs and template standards for RBM41
    OriGene qSTAR qPCR primer pairs in human, mouse for RBM41
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RBM41
      QuantiTect SYBR Green Assays in human, mouse, rat RBM41
      QuantiFast Probe-based Assays in human, mouse, rat RBM41

    Additional mRNA sequence: 

    AK001878.1 AL832966.1 BC006986.1 

    8 DOTS entries:

    DT.91707116  DT.91707114  DT.95218294  DT.97811715  DT.438162  DT.439117  DT.121316695  DT.95271071 

    Selected AceView cDNA sequences (see all 101):

    AK023732 BQ929508 AA579687 AL704471 CA414354 AI350695 AI393852 BU730024 
    BQ422014 BM704128 AL832966 BF589924 BP335213 CA412622 CF528890 AU136002 
    BE222249 BM697719 N35602 BQ773477 BP356239 CD244480 N29815 AA764918 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for RBM41    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9
    SP1:              -                                         -         
    SP2:              -                                                   
    SP3:                                                                  


    ECgene alternative splicing isoforms for RBM41

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RBM41 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGCTACAGGT
    RBM41 Expression
    About this image

    RBM41 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RBM41 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.139053
        Custom PCR Arrays for RBM41
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBM41

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for RBM41 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rbm411 , 5 RNA binding motif protein 411, 5 89.02(n)1
    87.41(a)1
      X (61.35 cM)5
    2370731  NM_153586.21  NP_705814.11 
     1399433735 
    chicken
    (Gallus gallus)
    Aves RBM411 RNA binding motif protein 41 62.85(n)
    56.49(a)
      428698  XM_004940608.1  XP_004940665.1 
    lizard
    (Anolis carolinensis)
    Reptilia RBM416
    RNA binding motif protein 41
    39(a)
    1 ↔ 1
    GL343376.1(1052652-1059869)
    zebrafish
    (Danio rerio)
    Actinopterygii rbm411 RNA binding motif protein 41 53.55(n)
    43.65(a)
      492764  NM_001007405.1  NP_001007406.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Snp6
    Snipper
    16(a)
    1 → many
    2R(17948458-17957262)


    ENSEMBL Gene Tree for RBM41 (if available)
    TreeFam Gene Tree for RBM41 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RBM41 gene
    RNPC32  

    Find genes that share paralogs with RBM41           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RBM41 (see all 784)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1888141761,2
    --106276438(+) TGTATA/GCTAAA 1 -- ds50010--------
    rs1818766071,2
    --106276653(+) GCCTCC/TGAAAG 1 -- ds50010--------
    rs1475354331,2
    C--106276685(+) CCACCA/GTGCCT 1 -- ds50010--------
    rs1138757421,2
    C--106276711(+) CTAAC-/TGATGATT 1 -- ds50011Minor allele frequency- TGA:0.00CSA 2
    rs793188861,2
    C--106276861(+) ATAACA/GTTTAT 1 -- ut310--------
    rs1876542681,2
    --106276934(+) AATGCA/GTATAC 1 -- ut310--------
    rs1506544191,2
    --106276978(+) AATTAC/TTAAGA 1 -- ut310--------
    rs1397965961,2
    --106277045(+) CATCCA/TCTGAA 1 -- ut310--------
    rs1497885881,2
    --106277370(+) AGCTTA/GGAAGT 1 -- ut310--------
    rs562873071,2
    C--106277402(+) AGAGGT/CTATAT 1 -- ut311Minor allele frequency- C:0.00WA 2

    HapMap Linkage Disequilibrium report for RBM41 (106305115 - 106362057 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for RBM41:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2675921CNV Deletion23128226
    esv2740376CNV Deletion23290073
    nsv7026CNV Loss18451855
    esv2752312CNV Gain17911159
    nsv519484CNV Gain19592680

    Locus Specific Mutation Databases (LSDB): RBM41

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RBM41
    DNA2.0 Custom Variant and Variant Library Synthesis for RBM41

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease for RBM41:    
    About MalaCards
    ebstein anomaly

    1 disease from the University of Copenhagen DISEASES database for RBM41:
    Ebstein anomaly

    Find genes that share disorders with RBM41           About GenesLikeMe


    Export disorders for RBM41 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RBM41 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with RBM41)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (Nature 2005)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    5. Tandem immunoprecipitation of phosphotyrosine-mass spectrometry (TIPY-MS) indicates C19ORF19 becomes tyrosine-phosphorylated and associated with activated epidermal growth factor receptor. (PubMed id 18271526)1 Tong J....Moran M.F. (J. Proteome Res. 2008)
    6. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008)
    7. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    8. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (Nature 2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55285 HGNC: 25617 AceView: FLJ11016 Ensembl:ENSG00000089682 euGenes: HUgn55285
    ECgene: RBM41 H-InvDB: RBM41

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RBM41 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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