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Aliases for RBM41 Gene

Aliases for RBM41 Gene

  • RNA Binding Motif Protein 41 2 3 5
  • RNA-Binding Motif Protein 41 4

External Ids for RBM41 Gene

Previous GeneCards Identifiers for RBM41 Gene

  • GC0XM106194
  • GC0XM106307
  • GC0XM095932

Summaries for RBM41 Gene

GeneCards Summary for RBM41 Gene

RBM41 (RNA Binding Motif Protein 41) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is RNPC3.

UniProtKB/Swiss-Prot for RBM41 Gene

  • May bind RNA.

Additional gene information for RBM41 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RBM41 Gene

Genomics for RBM41 Gene

GeneHancer (GH) Regulatory Elements for RBM41 Gene

Promoters and enhancers for RBM41 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XI107117 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 550.8 +0.3 348 2.2 PKNOX1 FOXA2 SIN3A ZNF2 YY1 ETS1 ZNF143 SP3 MAFF NR2C1 RBM41 FRMPD3 MYCLP1 RNF128 PIR50761 NUP62CL
GH0XI107450 Enhancer 1.1 Ensembl ENCODE 32.4 -332.3 -332259 1 GLI4 ZNF2 KLF7 ZNF548 SP3 YY2 TSHZ1 ZNF623 GLIS1 MYNN RBM41 RNF128 FRMPD3 KRT18P49
GH0XI107708 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 13.6 -595.5 -595485 10.9 HDGF PKNOX1 SMAD1 ARNT SIN3A YBX1 YY1 ZNF143 FOS JUNB TSC22D3 RBM41 MORC4 MID2 LOC101928335 ATG4A GC0XM107728 GC0XM107676
GH0XI107825 Promoter/Enhancer 2 EPDnew FANTOM5 Ensembl ENCODE 13 -707.6 -707638 2.7 PKNOX1 ARNT ZSCAN4 MZF1 SIN3A FEZF1 ZNF335 ZNF213 ZNF366 SP3 MID2 RBM41 NCBP2L LOC101928335 GC0XM107885
GH0XI107672 Enhancer 1.8 FANTOM5 Ensembl ENCODE dbSUPER 13.2 -557.6 -557572 7.7 PKNOX1 CLOCK ARNT SIN3A FEZF1 ZNF2 IRF4 POLR2B ZNF213 ZNF143 GC0XM107676 TSC22D3 RBM41 MORC4 RNF128 GC0XM107673
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around RBM41 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the RBM41 gene promoter:

Genomic Locations for RBM41 Gene

Genomic Locations for RBM41 Gene
chrX:107,061,885-107,118,827
(GRCh38/hg38)
Size:
56,943 bases
Orientation:
Minus strand
chrX:106,305,115-106,362,057
(GRCh37/hg19)

Genomic View for RBM41 Gene

Genes around RBM41 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RBM41 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RBM41 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RBM41 Gene

Proteins for RBM41 Gene

  • Protein details for RBM41 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96IZ5-RBM41_HUMAN
    Recommended name:
    RNA-binding protein 41
    Protein Accession:
    Q96IZ5
    Secondary Accessions:
    • Q5JSN7
    • Q5JSN8
    • Q9H8F7
    • Q9NV04

    Protein attributes for RBM41 Gene

    Size:
    413 amino acids
    Molecular mass:
    47100 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for RBM41 Gene

    Alternative splice isoforms for RBM41 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for RBM41 Gene

Post-translational modifications for RBM41 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RBM41 Gene

Domains & Families for RBM41 Gene

Gene Families for RBM41 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for RBM41 Gene

Suggested Antigen Peptide Sequences for RBM41 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RBM41: view

No data available for UniProtKB/Swiss-Prot for RBM41 Gene

Function for RBM41 Gene

Molecular function for RBM41 Gene

UniProtKB/Swiss-Prot Function:
May bind RNA.

Phenotypes From GWAS Catalog for RBM41 Gene

Gene Ontology (GO) - Molecular Function for RBM41 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003723 RNA binding IEA --
GO:0005515 protein binding IPI 16189514
GO:0030626 U12 snRNA binding IBA --
GO:0097157 pre-mRNA intronic binding IBA --
genes like me logo Genes that share ontologies with RBM41: view
genes like me logo Genes that share phenotypes with RBM41: view

Animal Model Products

miRNA for RBM41 Gene

miRTarBase miRNAs that target RBM41

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RBM41 Gene

Localization for RBM41 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for RBM41 gene
Compartment Confidence
nucleus 5
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nuclear speckles (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for RBM41 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005689 U12-type spliceosomal complex IBA --
genes like me logo Genes that share ontologies with RBM41: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for RBM41 Gene

Pathways & Interactions for RBM41 Gene

SuperPathways for RBM41 Gene

No Data Available

Gene Ontology (GO) - Biological Process for RBM41 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000398 mRNA splicing, via spliceosome IBA --
GO:0032502 developmental process IBA --
genes like me logo Genes that share ontologies with RBM41: view

No data available for Pathways by source and SIGNOR curated interactions for RBM41 Gene

Drugs & Compounds for RBM41 Gene

No Compound Related Data Available

Transcripts for RBM41 Gene

Unigene Clusters for RBM41 Gene

RNA binding motif protein 41:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for RBM41 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9
SP1: - -
SP2: -
SP3:

Relevant External Links for RBM41 Gene

GeneLoc Exon Structure for
RBM41
ECgene alternative splicing isoforms for
RBM41

Expression for RBM41 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RBM41 Gene

Protein differential expression in normal tissues from HIPED for RBM41 Gene

This gene is overexpressed in Spinal cord (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for RBM41 Gene



Protein tissue co-expression partners for RBM41 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of RBM41 Gene:

RBM41

SOURCE GeneReport for Unigene cluster for RBM41 Gene:

Hs.139053
genes like me logo Genes that share expression patterns with RBM41: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RBM41 Gene

Orthologs for RBM41 Gene

This gene was present in the common ancestor of animals.

Orthologs for RBM41 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia RBM41 33 34
  • 99.84 (n)
dog
(Canis familiaris)
Mammalia RBM41 33 34
  • 95.3 (n)
cow
(Bos Taurus)
Mammalia RBM41 34 33
  • 94.35 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia Rbm41 33
  • 90.07 (n)
mouse
(Mus musculus)
Mammalia Rbm41 16 34 33
  • 89.02 (n)
oppossum
(Monodelphis domestica)
Mammalia RBM41 34
  • 67 (a)
OneToOne
chicken
(Gallus gallus)
Aves RBM41 33 34
  • 62.85 (n)
lizard
(Anolis carolinensis)
Reptilia RBM41 34
  • 39 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii rbm41 33 34
  • 53.55 (n)
fruit fly
(Drosophila melanogaster)
Insecta Snp 34
  • 16 (a)
OneToMany
Species where no ortholog for RBM41 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RBM41 Gene

ENSEMBL:
Gene Tree for RBM41 (if available)
TreeFam:
Gene Tree for RBM41 (if available)

Paralogs for RBM41 Gene

Paralogs for RBM41 Gene

genes like me logo Genes that share paralogs with RBM41: view

Variants for RBM41 Gene

Sequence variations from dbSNP and Humsavar for RBM41 Gene

SNP ID Clin Chr 0X pos Variation AA Info Type
rs1000066288 -- 107,097,929(-) A/T intron_variant
rs1000100556 -- 107,109,798(-) T/C intron_variant
rs1000202901 -- 107,119,670(-) TAT/TATAT upstream_transcript_variant
rs1000224753 -- 107,119,643(-) C/T upstream_transcript_variant
rs1000239958 -- 107,108,881(-) G/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for RBM41 Gene

Variant ID Type Subtype PubMed ID
esv2675921 CNV deletion 23128226
esv2740376 CNV deletion 23290073
esv2752312 CNV gain 17911159
nsv519484 CNV gain 19592680
nsv7026 CNV deletion 18451855

Variation tolerance for RBM41 Gene

Residual Variation Intolerance Score: 31.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.94; 19.43% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for RBM41 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RBM41

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RBM41 Gene

Disorders for RBM41 Gene

Additional Disease Information for RBM41

No disorders were found for RBM41 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RBM41 Gene

Publications for RBM41 Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross MT … Bentley DR (Nature 2005) 3 4 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58

Products for RBM41 Gene

Sources for RBM41 Gene

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