Free for academic non-profit institutions. Other users need a Commercial license

Aliases for RBM34 Gene

Aliases for RBM34 Gene

  • RNA Binding Motif Protein 34 2 3 5
  • RNA-Binding Motif Protein 34 4
  • KIAA0117 4

External Ids for RBM34 Gene

Previous GeneCards Identifiers for RBM34 Gene

  • GC01M231489
  • GC01M233361
  • GC01M235294
  • GC01M205743

Summaries for RBM34 Gene

Entrez Gene Summary for RBM34 Gene

  • This gene encodes a member of the RNA-binding motif family of RNA recognition motif proteins. The encoded protein contains an RNA-binding domain made up of two RNA recognition motif subdomains referred to as RNA recognition motif-1 and RNA recognition motif-2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]

GeneCards Summary for RBM34 Gene

RBM34 (RNA Binding Motif Protein 34) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and nucleotide binding.

Gene Wiki entry for RBM34 Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RBM34 Gene

Genomics for RBM34 Gene

Regulatory Elements for RBM34 Gene

Enhancers for RBM34 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F235641 1.4 FANTOM5 Ensembl ENCODE 4.5 -481.0 -481049 2.1 KLF1 JUN KLF17 ZIC2 ZFHX2 POLR2A PATZ1 SCRT2 FOS CREM ENSG00000273058 ENSG00000230325 HEATR1 RPS21P1 GNG4 ARID4B LYST RBM34 LOC100131725
GH01F234837 1.9 FANTOM5 Ensembl ENCODE 3.3 +319.6 319616 8.4 MLX CREB3L1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 RPS21P1 IRF2BP2 ENSG00000228830 GGPS1 GNG4 LDHAP2 LINC01354 RBM34 RNY4P16 PIR44809
GH01F235289 1.7 FANTOM5 Ensembl ENCODE 3.2 -134.2 -134185 12.8 PKNOX1 ATF1 MLX ZFP64 ARID4B SIN3A ZNF121 GATA2 FOS ZNF202 ARID4B RPS21P1 GGPS1 LDHAP2 TOMM20 RBM34 RPL23AP23 GC01P235225
GH01F235304 1.4 FANTOM5 Ensembl ENCODE 3.1 -143.7 -143685 3.4 CTCF PKNOX1 FEZF1 ZNF121 ZNF316 GATA3 PRDM10 NR2F6 ZNF600 TCF7L2 ARID4B GGPS1 RBM34 GC01M235309 RPL23AP23
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around RBM34 on UCSC Golden Path with GeneCards custom track

Promoters for RBM34 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000168828 416 2001 HDGF ARNT CREB3L1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9

Genomic Location for RBM34 Gene

235,131,183 bp from pter
235,161,616 bp from pter
30,434 bases
Minus strand

Genomic View for RBM34 Gene

Genes around RBM34 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RBM34 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RBM34 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RBM34 Gene

Proteins for RBM34 Gene

  • Protein details for RBM34 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    RNA-binding protein 34
    Protein Accession:
    Secondary Accessions:
    • A8K8J7
    • Q8N2Z8
    • Q9H5A1

    Protein attributes for RBM34 Gene

    430 amino acids
    Molecular mass:
    48565 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH29451.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAA07503.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAF85051.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for RBM34 Gene


neXtProt entry for RBM34 Gene

Post-translational modifications for RBM34 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RBM34 Gene

No data available for DME Specific Peptides for RBM34 Gene

Domains & Families for RBM34 Gene

Gene Families for RBM34 Gene

Protein Domains for RBM34 Gene

Suggested Antigen Peptide Sequences for RBM34 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 2 RRM (RNA recognition motif) domains.
  • Belongs to the RRM RBM34 family.
  • Contains 2 RRM (RNA recognition motif) domains.
  • Belongs to the RRM RBM34 family.
genes like me logo Genes that share domains with RBM34: view

Function for RBM34 Gene

Gene Ontology (GO) - Molecular Function for RBM34 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0003676 nucleic acid binding IEA --
GO:0003723 RNA binding IEA --
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with RBM34: view

Phenotypes for RBM34 Gene

genes like me logo Genes that share phenotypes with RBM34: view

Animal Model Products

miRNA for RBM34 Gene

miRTarBase miRNAs that target RBM34

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RBM34 Gene

Localization for RBM34 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RBM34 Gene

Nucleus, nucleolus.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for RBM34 gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for RBM34 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
GO:0005730 nucleolus IDA --
genes like me logo Genes that share ontologies with RBM34: view

Pathways & Interactions for RBM34 Gene

SuperPathways for RBM34 Gene

No Data Available

Gene Ontology (GO) - Biological Process for RBM34 Gene


No data available for Pathways by source and SIGNOR curated interactions for RBM34 Gene

Transcripts for RBM34 Gene

Unigene Clusters for RBM34 Gene

RNA binding motif protein 34:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RBM34 Gene

No ASD Table

Relevant External Links for RBM34 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RBM34 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for RBM34 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for RBM34 Gene

This gene is overexpressed in Lung (52.7) and Peripheral blood mononuclear cells (6.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for RBM34 Gene

Protein tissue co-expression partners for RBM34 Gene

NURSA nuclear receptor signaling pathways regulating expression of RBM34 Gene:


SOURCE GeneReport for Unigene cluster for RBM34 Gene:

genes like me logo Genes that share expression patterns with RBM34: view

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RBM34 Gene

Orthologs for RBM34 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for RBM34 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia RBM34 34 35
  • 99.07 (n)
(Canis familiaris)
Mammalia RBM34 34 35
  • 84.48 (n)
(Bos Taurus)
Mammalia RBM34 35
  • 79 (a)
(Mus musculus)
Mammalia Rbm34 34 16 35
  • 77.28 (n)
(Rattus norvegicus)
Mammalia Rbm34 34
  • 76.91 (n)
(Monodelphis domestica)
Mammalia RBM34 35
  • 56 (a)
(Ornithorhynchus anatinus)
Mammalia RBM34 35
  • 56 (a)
(Gallus gallus)
Aves RBM34 34 35
  • 60.63 (n)
(Anolis carolinensis)
Reptilia RBM34 35
  • 49 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia rbm34 34
  • 57.39 (n)
(Danio rerio)
Actinopterygii rbm34 34 35
  • 56.4 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG12288 35
  • 23 (a)
(Caenorhabditis elegans)
Secernentea F11A10.7 35
  • 29 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes NOP12 35
  • 27 (a)
Species where no ortholog for RBM34 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RBM34 Gene

Gene Tree for RBM34 (if available)
Gene Tree for RBM34 (if available)

Paralogs for RBM34 Gene

No data available for Paralogs for RBM34 Gene

Variants for RBM34 Gene

Sequence variations from dbSNP and Humsavar for RBM34 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs111426285 -- 235,140,375(+) CACTC(A/G)GAGCA intron-variant
rs111447582 -- 235,144,583(+) AGCCA(A/G)GTCAA intron-variant
rs111494659 -- 235,154,432(+) GGTGG(C/T)GTGCG intron-variant
rs111517744 -- 235,153,856(+) GTTTT(C/G)CTTCA intron-variant
rs111556706 -- 235,156,157(+) GCCAC(C/T)GCGCC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RBM34 Gene

Variant ID Type Subtype PubMed ID
nsv508699 CNV deletion 20534489
esv3891237 CNV loss 25118596
esv3578486 CNV loss 25503493
esv3548744 CNV deletion 23714750
esv275126 CNV loss 21479260
esv2725296 CNV deletion 23290073
esv2670623 CNV deletion 23128226

Variation tolerance for RBM34 Gene

Residual Variation Intolerance Score: 87.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.40; 27.56% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RBM34 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RBM34 Gene

Disorders for RBM34 Gene

Relevant External Links for RBM34

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for RBM34 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RBM34 Gene

Publications for RBM34 Gene

  1. Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1. (PMID: 7788527) Nagase T. … Nomura N. (DNA Res. 1995) 2 3 4 64
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 64
  3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4 64
  4. Microarray analysis of differentially expressed genes in cells resistant to HIV-1. (PMID: 15134903) Kartvelishvili A. … Simm M. (Immunol. Lett. 2004) 2 3 64
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64

Products for RBM34 Gene

Sources for RBM34 Gene

Loading form....