RBM34 Gene
protein-coding GIFtS: 49
GCID: GC01M235294
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RNA binding motif protein 34
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Aliases for RBM34 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
| This gene clusters with an RNA gene Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| RNA Binding Motif Protein 341 2 | | KIAA01171 3 | | RNA-Binding Motif Protein 342 3 | | RNA-Binding Protein 342 |
| External Ids: | HGNC: 289651 | Entrez Gene: 230292 | Ensembl: ENSG000001887397 | UniProtKB: P426963 | | ORGUL members: | |
|---|
| NONCODE:n408007 | |
Export aliases for RBM34 gene to outside databasesPrevious GC identifers: GC01M231489 GC01M233361 GC01M205743
Summaries for RBM34 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Gene Wiki entry for RBM34
|
Genomic Views for RBM34 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_167186.1
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the RBM34 gene promoter: HOXA9 HOXA9B POU2F1 FOXJ2 (long isoform) POU2F1a FOXO1a STAT3 Meis-1a FOXO1 Meis-1 Other transcription factors
Search SABiosciences Chromatin IP Primers for RBM34
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RBM34 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q42.3 Ensembl cytogenetic band: 1q42.3 HGNC cytogenetic band: 1q42.3RBM34 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M235294: view genomic region
(about GC identifiers)
Start:
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235,294,498 bp from pter |
End:
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235,324,772 bp from pter |
Size:
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30,275 bases |
Orientation:
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minus strand |
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Proteins for RBM34 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: RBM34_HUMAN, P42696 (See
protein sequence)Recommended Name: RNA-binding protein 34 Size: 430 amino acids; 48565 Da
Subcellular location: Nucleus, nucleolus
Sequence caution: Sequence=AAH29451.1; Type=Erroneous initiation; Sequence=BAA07503.1; Type=Erroneous initiation;Sequence=BAF85051.1; Type=Erroneous initiation;
Secondary accessions: A8K8J7 Q8N2Z8 Q9H5A1Alternative splicing: 2 isoforms: P42696-1 P42696-2 (May be due to an intron retention)Explore the universe of human proteins at neXtProt for RBM34: NX_P42696
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P42696 RBM34 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001155005.1 NP_055829.2 ENSEMBL proteins: ENSP00000386226 ENSP00000400000 ENSP00000420236 ENSP00000413409 ENSP00000355565 Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
RBM34 for ontologies About GeneDecksing
RBM34 Antibody Products: Assay Products for RBM34: |
Protein
Domains / Families for RBM34 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RBM34 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P42696ProtoNet protein and cluster: P42696 1 Blocks protein family: IPB000504 RNA-binding region RNP-1 (RNA recognition motif)
UniProtKB/Swiss-Prot: RBM34_HUMAN, P42696Similarity: Belongs to the RRM RBM34 familySimilarity: Contains 2 RRM (RNA recognition motif) domains |
Function for RBM34 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RBM34 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RBM34 (see all 5) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): RBM34 (NM_001161533) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RBM34 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RBM34  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBM34 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
RBM34 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for RBM34:
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Pathways & Interactions for RBM34 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RBM34
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/43 Interacting proteins for RBM34 (P426963 ENSP000003555654) via UniProtKB, MINT, STRING, and/or I2D (see all 43)About this table
|
Drugs & Compounds for RBM34 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for RBM34 Search CenterWatch for drugs/clinical trials and news about RBM34 
|
Transcripts for RBM34 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for RBM34 gene (2 alternative transcripts): NM_001161533.1 NM_015014.2 Unigene Cluster for RBM34: RNA binding motif protein 34 Hs.535224 [show with all ESTs]Unigene Representative Sequence: NM_01501411 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000408888(uc001hwn.3 uc001hwo.3 uc010pxp.1) ENST00000495224 ENST00000447801 ENST00000474086 ENST00000476261 ENST00000468751 ENST00000429912 ENST00000475960 ENST00000486751 ENST00000485019 ENST00000366606
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RBM34 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RBM34 (see all 5) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): RBM34 (NM_001161533) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RBM34 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RBM34  |
Additional cDNA sequence: AK292362.1 BC029451.1 D38491.1 NR_027762.1 18 DOTS entries: DT.315604 DT.100823464 DT.92433236 DT.100696358 DT.95198870 DT.75186254 DT.95089620 DT.121438660 DT.91666783 DT.95089619 DT.100844666 DT.452426 DT.95089630 DT.92037159 DT.100823448 DT.75127825 DT.92433237 DT.95096479 24/198 AceView cDNA sequences (see all 198): AI383138 AI342592 BQ026989 AI858562 AA743611 AA447551 CR615831 BU632835 CB115829 CB150476 D38491 CB142607 BQ924877 BU076256 CB116435 AI476616 AU123670 AI343363 BQ446327 BF513421 NM_015014 BU609087 AI937399 CR609536 GeneLoc Exon Structure
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Expression for RBM34 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RBM34 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: CGTTCTGTTA
About this image See RBM34 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for RBM34
SOURCE GeneReport for Unigene cluster: Hs.535224 SABiosciences Custom PCR Arrays for RBM34
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RBM34 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RBM34 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RBM34 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RBM34 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBM34 |
Orthologs for RBM34 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for RBM34 gene from 10/27 species (see all 27) About this table
ENSEMBL Gene Tree for RBM34 (if available) TreeFam Gene Tree for RBM34 (if available)  |
Paralogs for RBM34 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for RBM34 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 1 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for RBM34 (235294498 - 235324772 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for RBM34: --  | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases for RBM34 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RBM34 for disorders About GeneDecksing
1 disease for RBM34: About MalaCardsmalaria Export disorders for RBM34 gene to outside databases
|
Publications for RBM34 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RBM34 gene, integrated from 9 sources (see all 21): (articles sorted by number of sources associating them with RBM34) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 7788527)1, 2, 3 Nagase T....Kotani H. (1995)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- Microarray analysis of differentially expressed genes in cells resistant to HIV-1. (PubMed id 15134903)1, 3 Kartvelishvili A....Simm M. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (2002)
- Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyc losome substrate. (PubMed id 21628590)1 Emanuele M.J....Elledge S.J. (2011)
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
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External Searches for RBM34 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing RBM34 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RBM34 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing RBM34 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for RBM34 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for RBM34 gene: Search GeneIP for patents involving RBM34
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for RBM34 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
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 | |
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| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for RBM34 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RBM34 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RBM34 | | OriGene Protein Over-expression Lysate for RBM34 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for RBM34 | | OriGene 3'-UTR Clone for RBM34 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RBM34 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RBM34 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for RBM34 | | OriGene Custom Protein Services for RBM34 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RBM34 | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RBM34 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RBM34 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RBM34 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RBM34 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RBM34 |
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 |  |  |  | |
| | | Search Tocris compounds for RBM34 |
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 | | RBM34 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBM34 |
|  |  |  | | | ThermoFisher Antibodies for RBM34 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RBM34 |
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Last full update: 19 Mar 2013 -
Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013
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