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Aliases for RBM27 Gene

Aliases for RBM27 Gene

  • RNA Binding Motif Protein 27 2 3 5
  • Acidic Rich RS Domain Containing 1 2 3
  • RNA-Binding Motif Protein 27 3 4
  • KIAA1311 4
  • ZC3H18 3
  • ZC3H20 3
  • ARRS1 3
  • Psc1 3

External Ids for RBM27 Gene

Previous GeneCards Identifiers for RBM27 Gene

  • GC05P145613
  • GC05P145563
  • GC05U900595
  • GC05P141098

Summaries for RBM27 Gene

GeneCards Summary for RBM27 Gene

RBM27 (RNA Binding Motif Protein 27) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is ENSG00000275740.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RBM27 Gene

Genomics for RBM27 Gene

Regulatory Elements for RBM27 Gene

Enhancers for RBM27 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around RBM27 on UCSC Golden Path with GeneCards custom track

Promoters for RBM27 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around RBM27 on UCSC Golden Path with GeneCards custom track

Genomic Location for RBM27 Gene

146,203,550 bp from pter
146,289,223 bp from pter
85,674 bases
Plus strand

Genomic View for RBM27 Gene

Genes around RBM27 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RBM27 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RBM27 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RBM27 Gene

Proteins for RBM27 Gene

  • Protein details for RBM27 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    RNA-binding protein 27
    Protein Accession:
    Secondary Accessions:
    • Q8IYW9

    Protein attributes for RBM27 Gene

    1060 amino acids
    Molecular mass:
    118718 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RBM27 Gene

Proteomics data for RBM27 Gene at MOPED

Post-translational modifications for RBM27 Gene

  • Ubiquitination at Lys 653
  • Modification sites at PhosphoSitePlus

Other Protein References for RBM27 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RBM27 Gene

Domains & Families for RBM27 Gene

Suggested Antigen Peptide Sequences for RBM27 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • The RRM domain mediates integration into cytospeckles.
  • Contains 1 C3H1-type zinc finger.
  • The RRM domain mediates integration into cytospeckles.
  • Contains 1 RRM (RNA recognition motif) domain.
  • Contains 1 C3H1-type zinc finger.
genes like me logo Genes that share domains with RBM27: view

Function for RBM27 Gene

Gene Ontology (GO) - Molecular Function for RBM27 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with RBM27: view
genes like me logo Genes that share phenotypes with RBM27: view

Animal Model Products

miRNA for RBM27 Gene

miRTarBase miRNAs that target RBM27

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RBM27 Gene

Localization for RBM27 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RBM27 Gene

Cytoplasm. Nucleus speckle. Note=Incorporated into the nuclear speckles and to speckles proximal to the nuclear periphery. Also localizes to punctate structures in the cytoplasm termed cytospeckles (By similarity). {ECO:0000250}.

Subcellular locations from

Jensen Localization Image for RBM27 Gene COMPARTMENTS Subcellular localization image for RBM27 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for RBM27 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with RBM27: view

Pathways & Interactions for RBM27 Gene

SuperPathways for RBM27 Gene

No Data Available

Gene Ontology (GO) - Biological Process for RBM27 Gene


No data available for Pathways by source and SIGNOR curated interactions for RBM27 Gene

Drugs & Compounds for RBM27 Gene

No Compound Related Data Available

Transcripts for RBM27 Gene

Unigene Clusters for RBM27 Gene

RNA binding motif protein 27:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RBM27 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20
SP1: - -

Relevant External Links for RBM27 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RBM27 Gene

mRNA expression in normal human tissues for RBM27 Gene

Protein differential expression in normal tissues from HIPED for RBM27 Gene

This gene is overexpressed in Breast (27.2) and Synovial fluid (7.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for RBM27 Gene

SOURCE GeneReport for Unigene cluster for RBM27 Gene Hs.61441

genes like me logo Genes that share expression patterns with RBM27: view

Protein tissue co-expression partners for RBM27 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RBM27 Gene

Orthologs for RBM27 Gene

This gene was present in the common ancestor of animals.

Orthologs for RBM27 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia RBM27 35
  • 92.91 (n)
  • 96.88 (a)
RBM27 36
  • 97 (a)
(Canis familiaris)
Mammalia RBM27 35
  • 93.93 (n)
  • 97.36 (a)
RBM27 36
  • 97 (a)
(Mus musculus)
Mammalia Rbm27 35
  • 89.64 (n)
  • 93.63 (a)
Rbm27 16
Rbm27 36
  • 95 (a)
(Pan troglodytes)
Mammalia RBM27 35
  • 99.72 (n)
  • 99.81 (a)
RBM27 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Rbm27 35
  • 90.9 (n)
  • 95.28 (a)
(Monodelphis domestica)
Mammalia RBM27 36
  • 89 (a)
(Ornithorhynchus anatinus)
Mammalia RBM27 36
  • 87 (a)
(Gallus gallus)
Aves RBM27 35
  • 75.66 (n)
  • 80.75 (a)
RBM27 36
  • 78 (a)
(Anolis carolinensis)
Reptilia RBM27 36
  • 75 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia rbm27 35
  • 68.6 (n)
  • 69.2 (a)
Str.19140 35
(Danio rerio)
Actinopterygii Dr.15505 35
rbm27 35
  • 59.02 (n)
  • 58.5 (a)
rbm27 36
  • 52 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.2616 35
fruit fly
(Drosophila melanogaster)
Insecta swm 36
  • 24 (a)
(Caenorhabditis elegans)
Secernentea B0336.3 36
  • 27 (a)
Species with no ortholog for RBM27:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RBM27 Gene

Gene Tree for RBM27 (if available)
Gene Tree for RBM27 (if available)

Paralogs for RBM27 Gene

Paralogs for RBM27 Gene

(7) SIMAP similar genes for RBM27 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with RBM27: view

Variants for RBM27 Gene

Sequence variations from dbSNP and Humsavar for RBM27 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs2895652 -- 146,228,005(+) ATAAC(C/T)GTTTT intron-variant
rs2895653 -- 146,271,449(+) AATAA(C/G/T)GTATG intron-variant, downstream-variant-500B
rs2915796 -- 146,259,134(-) CATTG(A/C)TAGTG intron-variant
rs2939523 -- 146,278,505(-) atata(C/G/T)aGAGA intron-variant
rs2939524 -- 146,270,609(-) TTATA(A/G)TACAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RBM27 Gene

Variant ID Type Subtype PubMed ID
nsv883006 CNV Loss 21882294
nsv428128 CNV Loss 18775914
dgv6355n71 CNV Loss 21882294
dgv6356n71 CNV Loss 21882294
dgv6357n71 CNV Loss 21882294
nsv523502 CNV Gain 19592680
dgv725n27 CNV Loss 19166990
nsv517251 CNV Loss 19592680
nsv462478 CNV Loss 19166990

Variation tolerance for RBM27 Gene

Residual Variation Intolerance Score: 4.36% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.55; 30.06% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for RBM27 Gene

Disorders for RBM27 Gene

Relevant External Links for RBM27

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for RBM27 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RBM27 Gene

Publications for RBM27 Gene

  1. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10718198) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4 67
  2. A family of RS domain proteins with novel subcellular localization and trafficking. (PMID: 15741184) Kavanagh S.J. … Rathjen P.D. (Nucleic Acids Res. 2005) 2 3
  3. Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes. (PMID: 25281560) Lambert J.P. … Gingras A.C. (J Proteomics 2015) 3
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  5. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3

Products for RBM27 Gene

Sources for RBM27 Gene