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Aliases for RBM26 Gene

Aliases for RBM26 Gene

  • RNA Binding Motif Protein 26 2 3 5
  • Protein Phosphatase 1, Regulatory 132 2 3
  • Acidic Rich RS Domain Containing 2 2 3
  • CTCL Tumor Antigen Se70-2 3 4
  • C13orf10 3 4
  • Cutaneous T-Cell Lymphoma Tumor Antigen Se70-2 3
  • Chromosome 13 Open Reading Frame 10 2
  • RNA-Binding Motif Protein 26 4
  • RNA-Binding Protein 26 3
  • PPP1R132 3
  • PRO1777 3
  • SE70-2 3
  • ZC3H17 3
  • ARRS2 3

External Ids for RBM26 Gene

Previous HGNC Symbols for RBM26 Gene

  • C13orf10

Previous GeneCards Identifiers for RBM26 Gene

  • GC13M078783
  • GC13M079888
  • GC13M060597

Summaries for RBM26 Gene

GeneCards Summary for RBM26 Gene

RBM26 (RNA Binding Motif Protein 26) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is RBM27.

Gene Wiki entry for RBM26 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RBM26 Gene

Genomics for RBM26 Gene

Regulatory Elements for RBM26 Gene

Enhancers for RBM26 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH13G079380 0.9 Ensembl ENCODE 22.2 +24.4 24429 2.5 PKNOX1 ZNF146 TBX21 ZNF664 ARID3A PBX2 ETV6 PRDM1 TRIM28 RBM26-AS1 RBM26 LINC01068 RNA5SP33 GC13M079201
GH13G079392 1.6 Ensembl ENCODE dbSUPER 11 +12.4 12441 2.7 PKNOX1 FOXA2 MLX WRNIP1 ARID4B FEZF1 DMAP1 ZNF766 CBX5 MXD4 LINC01068 RBM26 RNA5SP33 RBM26-AS1
GH13G079402 1.3 ENCODE dbSUPER 11.5 +1.5 1482 5.0 HDGF PKNOX1 FOXA2 CREB3L1 ARNT WRNIP1 ARID4B SIN3A DMAP1 ZNF2 RBM26-AS1 RBM26 RNA5SP33
GH13G079401 1.3 Ensembl ENCODE dbSUPER 11.2 +4.5 4538 1.0 PKNOX1 BACH1 FEZF1 ZNF384 ZBTB40 ZNF316 ZNF600 NFE2 MAFK NFE2L2 RBM26 RBM26-AS1 RNA5SP33
GH13G079280 1 ENCODE dbSUPER 12.4 +124.2 124186 2.8 TAF1 TEAD4 MAX CEBPG RAD21 YY1 HNF4G EZH2 GATAD2A HLF RBM26 GC13M079201 RNA5SP33
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around RBM26 on UCSC Golden Path with GeneCards custom track

Promoters for RBM26 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000064120 677 2801 HDGF PKNOX1 FOXA2 CREB3L1 ARNT WRNIP1 ARID4B SIN3A DMAP1 ZNF2

Genomic Location for RBM26 Gene

Chromosome:
13
Start:
79,311,824 bp from pter
End:
79,406,477 bp from pter
Size:
94,654 bases
Orientation:
Minus strand

Genomic View for RBM26 Gene

Genes around RBM26 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RBM26 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RBM26 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RBM26 Gene

Proteins for RBM26 Gene

  • Protein details for RBM26 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T8P6-RBM26_HUMAN
    Recommended name:
    RNA-binding protein 26
    Protein Accession:
    Q5T8P6
    Secondary Accessions:
    • B4DZE0
    • Q2NKM2
    • Q2NKQ2
    • Q5CZH8
    • Q5T8P5
    • Q5T8P8
    • Q5U5P5
    • Q5W0G7
    • Q8N3H5
    • Q96K92
    • Q96SZ3
    • Q9H2F8
    • Q9H7F9
    • Q9P1G7

    Protein attributes for RBM26 Gene

    Size:
    1007 amino acids
    Molecular mass:
    113597 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAG34912.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAB14933.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAB55125.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI12921.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI95136.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for RBM26 Gene

neXtProt entry for RBM26 Gene

Post-translational modifications for RBM26 Gene

  • Ubiquitination at Lys71 and Lys709
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for RBM26 Gene

Domains & Families for RBM26 Gene

Protein Domains for RBM26 Gene

Suggested Antigen Peptide Sequences for RBM26 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RBM26: view

No data available for UniProtKB/Swiss-Prot for RBM26 Gene

Function for RBM26 Gene

Gene Ontology (GO) - Molecular Function for RBM26 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003723 RNA binding IDA,IEA 22658674
GO:0005515 protein binding IPI 17577209
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with RBM26: view
genes like me logo Genes that share phenotypes with RBM26: view

Animal Model Products

CRISPR Products

miRNA for RBM26 Gene

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RBM26 Gene

Localization for RBM26 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for RBM26 gene
Compartment Confidence
nucleus 5
mitochondrion 2
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for RBM26 Gene

Pathways & Interactions for RBM26 Gene

SuperPathways for RBM26 Gene

No Data Available

Gene Ontology (GO) - Biological Process for RBM26 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006397 mRNA processing IEA --
GO:0010923 negative regulation of phosphatase activity IDA 19389623
genes like me logo Genes that share ontologies with RBM26: view

No data available for Pathways by source and SIGNOR curated interactions for RBM26 Gene

Drugs & Compounds for RBM26 Gene

No Compound Related Data Available

Transcripts for RBM26 Gene

Unigene Clusters for RBM26 Gene

RNA binding motif protein 26:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for RBM26 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b · 10c ^ 11a · 11b · 11c · 11d ^ 12a · 12b · 12c ^ 13 ^ 14a ·
SP1: - - -
SP2: - -
SP3:
SP4:
SP5: -
SP6:
SP7:
SP8:
SP9:
SP10:
SP11: -
SP12:
SP13:
SP14:
SP15:
SP16:

ExUns: 14b ^ 15a · 15b · 15c ^ 16 ^ 17a · 17b · 17c ^ 18a · 18b ^ 19 ^ 20a · 20b ^ 21a · 21b · 21c · 21d ^ 22 ^ 23a · 23b ^ 24a · 24b
SP1: - - - - - -
SP2: - - - - -
SP3: - -
SP4: -
SP5:
SP6: -
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15: - - -
SP16: -

Relevant External Links for RBM26 Gene

GeneLoc Exon Structure for
RBM26
ECgene alternative splicing isoforms for
RBM26

Expression for RBM26 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RBM26 Gene

Protein differential expression in normal tissues from HIPED for RBM26 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (10.5), Heart (8.1), and CD8 Tcells (7.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for RBM26 Gene



Protein tissue co-expression partners for RBM26 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of RBM26 Gene:

RBM26

SOURCE GeneReport for Unigene cluster for RBM26 Gene:

Hs.558528

Evidence on tissue expression from TISSUES for RBM26 Gene

  • Nervous system(4.5)
  • Liver(4.3)
genes like me logo Genes that share expression patterns with RBM26: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for RBM26 Gene

Orthologs for RBM26 Gene

This gene was present in the common ancestor of animals.

Orthologs for RBM26 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia RBM26 34 35
  • 99.66 (n)
dog
(Canis familiaris)
Mammalia RBM26 34 35
  • 95.44 (n)
cow
(Bos Taurus)
Mammalia RBM26 34 35
  • 95.34 (n)
mouse
(Mus musculus)
Mammalia Rbm26 34 16 35
  • 91.63 (n)
rat
(Rattus norvegicus)
Mammalia Rbm26 34
  • 90.71 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia RBM26 35
  • 88 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia RBM26 35
  • 82 (a)
OneToOne
chicken
(Gallus gallus)
Aves RBM26 34 35
  • 81.53 (n)
lizard
(Anolis carolinensis)
Reptilia RBM26 35
  • 86 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.2802 34
African clawed frog
(Xenopus laevis)
Amphibia MGC52868 34
zebrafish
(Danio rerio)
Actinopterygii RBM26 35
  • 68 (a)
OneToOne
rbm26 34
  • 65.46 (n)
fruit fly
(Drosophila melanogaster)
Insecta swm 35
  • 25 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea B0336.3 35
  • 29 (a)
OneToMany
Species where no ortholog for RBM26 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RBM26 Gene

ENSEMBL:
Gene Tree for RBM26 (if available)
TreeFam:
Gene Tree for RBM26 (if available)

Paralogs for RBM26 Gene

Paralogs for RBM26 Gene

(2) SIMAP similar genes for RBM26 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with RBM26: view

Variants for RBM26 Gene

Sequence variations from dbSNP and Humsavar for RBM26 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type
rs1000013073 -- 79,407,750(+) TGGCT(C/T)TCCAC intron-variant, upstream-variant-2KB
rs1000017803 -- 79,386,183(+) AAATA(C/T)CTTTG intron-variant
rs1000024243 -- 79,347,565(+) GAGAC(A/G)GTGAC intron-variant
rs1000110420 -- 79,337,144(+) GTAAA(C/T)GCAGA reference, synonymous-codon
rs1000113467 -- 79,380,825(+) ACTTA(C/T)ATGAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RBM26 Gene

Variant ID Type Subtype PubMed ID
esv1133660 CNV deletion 17803354
esv2747705 CNV deletion 23290073
esv3580777 CNV loss 25503493
esv3632814 CNV gain 21293372
esv3632816 CNV gain 21293372
esv3632819 CNV gain 21293372
nsv523979 CNV loss 19592680
nsv64406 CNV deletion 16902084
nsv64617 CNV deletion 16902084
nsv64677 CNV deletion 16902084
nsv832657 CNV gain 17160897
nsv957439 CNV deletion 24416366

Variation tolerance for RBM26 Gene

Residual Variation Intolerance Score: 8.49% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.80; 66.86% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RBM26 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RBM26

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RBM26 Gene

Disorders for RBM26 Gene

Relevant External Links for RBM26

Genetic Association Database (GAD)
RBM26
Human Genome Epidemiology (HuGE) Navigator
RBM26
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
RBM26

No disorders were found for RBM26 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RBM26 Gene

Publications for RBM26 Gene

  1. Serological detection of cutaneous T-cell lymphoma-associated antigens. (PMID: 11149944) Eichmueller S. … Schadendorf D. (Proc. Natl. Acad. Sci. U.S.A. 2001) 2 3 4 64
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
  3. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PMID: 16964243) Beausoleil S.A. … Gygi S.P. (Nat. Biotechnol. 2006) 3 4 64
  4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4 64
  5. A family of RS domain proteins with novel subcellular localization and trafficking. (PMID: 15741184) Kavanagh S.J. … Rathjen P.D. (Nucleic Acids Res. 2005) 2 3 64

Products for RBM26 Gene

Sources for RBM26 Gene

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