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Aliases for RBM23 Gene

Aliases for RBM23 Gene

  • RNA Binding Motif Protein 23 2 3
  • Coactivator Of Activating Protein-1 And Estrogen Recep- Tors Beta 2 3
  • RNA-Binding Region (RNP1, RRM) Containing 4 2 3
  • RNA-Binding Region-Containing Protein 4 3 4
  • RNA-Binding Motif Protein 23 3 4
  • Splicing Factor SF2 3 4
  • RNPC4 3 4
  • Probable RNA-Binding Protein 23 3
  • CAPERbeta 3
  • PP239 3

External Ids for RBM23 Gene

Previous HGNC Symbols for RBM23 Gene

  • RNPC4

Previous GeneCards Identifiers for RBM23 Gene

  • GC14M021361
  • GC14M022439
  • GC14M023369
  • GC14M003486

Summaries for RBM23 Gene

Entrez Gene Summary for RBM23 Gene

  • This gene encodes a member of the U2AF-like family of RNA binding proteins. This protein interacts with some steroid nuclear receptors, localizes to the promoter of a steroid- responsive gene, and increases transcription of steroid-responsive transcriptional reporters in a hormone-dependent manner. It is also implicated in the steroid receptor-dependent regulation of alternative splicing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

GeneCards Summary for RBM23 Gene

RBM23 (RNA Binding Motif Protein 23) is a Protein Coding gene. GO annotations related to this gene include RNA binding and nucleotide binding. An important paralog of this gene is RBM39.

UniProtKB/Swiss-Prot for RBM23 Gene

  • Probable RNA-binding protein. May be involved in pre-mRNA splicing process

Gene Wiki entry for RBM23 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RBM23 Gene

Genomics for RBM23 Gene

Regulatory Elements for RBM23 Gene

Genomic Location for RBM23 Gene

Start:
22,900,645 bp from pter
End:
22,919,187 bp from pter
Size:
18,543 bases
Orientation:
Minus strand

Genomic View for RBM23 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RBM23 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RBM23 Gene

Proteins for RBM23 Gene

  • Protein details for RBM23 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86U06-RBM23_HUMAN
    Recommended name:
    Probable RNA-binding protein 23
    Protein Accession:
    Q86U06
    Secondary Accessions:
    • D3DS32
    • Q8ND16
    • Q8TB88
    • Q8WY40
    • Q9BUJ1
    • Q9NVV7

    Protein attributes for RBM23 Gene

    Size:
    439 amino acids
    Molecular mass:
    48731 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for RBM23 Gene

    Alternative splice isoforms for RBM23 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for RBM23 Gene

Proteomics data for RBM23 Gene at MOPED

Post-translational modifications for RBM23 Gene

  • Ubiquitination at Lys245
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for RBM23 Gene

Domains for RBM23 Gene

Gene Families for RBM23 Gene

HGNC:
  • RBM :RNA binding motif (RRM) containing

Suggested Antigen Peptide Sequences for RBM23 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q86U06

UniProtKB/Swiss-Prot:

RBM23_HUMAN :
  • Q86U06
Domain:
  • Contains 2 RRM (RNA recognition motif) domains.
Family:
  • Belongs to the splicing factor SR family.
genes like me logo Genes that share domains with RBM23: view

Function for RBM23 Gene

Molecular function for RBM23 Gene

UniProtKB/Swiss-Prot Function: Probable RNA-binding protein. May be involved in pre-mRNA splicing process

Gene Ontology (GO) - Molecular Function for RBM23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0003676 nucleic acid binding --
GO:0003723 RNA binding IEA --
GO:0005515 protein binding IPI 22365833
genes like me logo Genes that share ontologies with RBM23: view
genes like me logo Genes that share phenotypes with RBM23: view

miRNA for RBM23 Gene

miRTarBase miRNAs that target RBM23

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for RBM23 Gene

Localization for RBM23 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RBM23 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RBM23 Gene COMPARTMENTS Subcellular localization image for RBM23 gene
Compartment Confidence
nucleus 3
cytoskeleton 1

Gene Ontology (GO) - Cellular Components for RBM23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0016020 membrane IDA 19946888
genes like me logo Genes that share ontologies with RBM23: view

Pathways for RBM23 Gene

SuperPathways for RBM23 Gene

No Data Available

Gene Ontology (GO) - Biological Process for RBM23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006397 mRNA processing IEA --
genes like me logo Genes that share ontologies with RBM23: view

No data available for Pathways by source for RBM23 Gene

Transcripts for RBM23 Gene

Unigene Clusters for RBM23 Gene

RNA binding motif protein 23:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RBM23 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d ^ 8 ^ 9a · 9b · 9c ^ 10a · 10b · 10c ^ 11 ^ 12a · 12b · 12c ^
SP1: - - - - - - - -
SP2: - - - - - - -
SP3: - - - - - - - - - - -
SP4: - - - - - - - -
SP5: - - - - - - - - - -
SP6: - - - - - - - - -
SP7: - - - - - - -
SP8: - - - - - - -
SP9: - - - - - - - - -
SP10: - - - - - - - - - -
SP11: - - - - - - - -
SP12: - - - - - - - - - - - -
SP13: - - - - - - - - - - -
SP14: - - - - - - -
SP15:
SP16: - - -
SP17: - - - - - - - - - -
SP18: - -
SP19: - - - -
SP20:
SP21:
SP22: -
SP23: - - - - - -

ExUns: 13 ^ 14a · 14b · 14c ^ 15a · 15b · 15c ^ 16 ^ 17 ^ 18
SP1: - - -
SP2:
SP3: - - -
SP4: - - -
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15: - - -
SP16:
SP17:
SP18:
SP19:
SP20:
SP21: -
SP22:
SP23:

Relevant External Links for RBM23 Gene

GeneLoc Exon Structure for
RBM23
ECgene alternative splicing isoforms for
RBM23

Expression for RBM23 Gene

mRNA expression in normal human tissues for RBM23 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for RBM23 Gene

SOURCE GeneReport for Unigene cluster for RBM23 Gene Hs.4997

genes like me logo Genes that share expressions with RBM23: view

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RBM23 Gene

Orthologs for RBM23 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for RBM23 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia RBM23 35
  • 97.87 (n)
  • 97.04 (a)
RBM23 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia RBM23 35
  • 88.38 (n)
  • 90.89 (a)
RBM23 36
  • 83 (a)
OneToOne
dog
(Canis familiaris)
Mammalia RBM23 35
  • 87.02 (n)
  • 90.89 (a)
RBM23 36
  • 81 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia RBM23 36
  • 84 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia RBM23 36
  • 58 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia RBM23 36
  • 68 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia rbm23 35
  • 65.12 (n)
  • 72.13 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG11266 36
  • 36 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea Y55F3AM.3 36
  • 29 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes NOP13 36
  • 21 (a)
ManyToMany
RNA15 36
  • 14 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 43 (a)
OneToMany
Species with no ortholog for RBM23:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for RBM23 Gene

ENSEMBL:
Gene Tree for RBM23 (if available)
TreeFam:
Gene Tree for RBM23 (if available)

Paralogs for RBM23 Gene

Paralogs for RBM23 Gene

genes like me logo Genes that share paralogs with RBM23: view

Variants for RBM23 Gene

Sequence variations from dbSNP and Humsavar for RBM23 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs7469 -- 22,900,988(-) CTTGT(C/T)CTTCC utr-variant-3-prime, nc-transcript-variant
rs11882 -- 22,900,960(+) TACCT(C/T)GGGCC utr-variant-3-prime, nc-transcript-variant
rs967518 -- 22,905,025(-) CATTT(C/T)CTCCT intron-variant
rs1043207 -- 22,900,785(-) ATATA(C/T)ATAAA utr-variant-3-prime, nc-transcript-variant
rs1043209 -- 22,904,777(+) CAGCA(A/G)GTTAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RBM23 Gene

Variant ID Type Subtype PubMed ID
dgv385e199 CNV Deletion 23128226

Relevant External Links for RBM23 Gene

HapMap Linkage Disequilibrium report
RBM23

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RBM23 Gene

Disorders for RBM23 Gene

Relevant External Links for RBM23

Human Genome Epidemiology (HuGE) Navigator
RBM23
genes like me logo Genes that share disorders with RBM23: view

No data available for UniProtKB/Swiss-Prot for RBM23 Gene

Publications for RBM23 Gene

  1. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4
  2. The DNA sequence and analysis of human chromosome 14. (PMID: 12508121) Heilig R. … Weissenbach J. (Nature 2003) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Large-scale cDNA transfection screening for genes related to cancer development and progression. (PMID: 15498874) Wan D. … Gu J. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4

Products for RBM23 Gene

Sources for RBM23 Gene

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