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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RBM22 Gene

protein-coding   GIFtS: 52
GCID: GC05M150050

RNA Binding Motif Protein 22

  Search for RBM22
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
RNA Binding Motif Protein 221 2     RNA-Binding Motif Protein 222 3
Functional Spliceosome-Associated Protein 471 2     Cwc22
Zinc Finger CCCH Domain-Containing Protein 162 3     fSAP472
ZC3H162 3     Pre-MRNA-Splicing Factor RBM222

External Ids:    HGNC: 255031   Entrez Gene: 556962   Ensembl: ENSG000000865897   OMIM: 6124305   UniProtKB: Q9NW643   

Export aliases for RBM22 gene to outside databases

Previous GC identifers: GC05M150099 GC05M145216


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RBM22 Gene:
This gene encodes an RNA binding protein. The encoded protein may play a role in cell division and may be involved
in pre-mRNA splicing. Related pseudogenes exist on chromosomes 6, 7, 9, 13, 16, 18, and X. (provided by RefSeq,
Mar 2009)

GeneCards Summary for RBM22 Gene: 
RBM22 (RNA binding motif protein 22) is a protein-coding gene. Among its related super-pathways are mRNA Splicing - Major Pathway. GO annotations related to this gene include nucleocytoplasmic transporter activity and nucleotide binding.

UniProtKB/Swiss-Prot: RBM22_HUMAN, Q9NW64
Function: Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain
of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of
the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic
calcium-binding protein PDCD6 to the nucleus upon cellular stress responses

Gene Wiki entry for RBM22 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NT_029289.11  NC_018916.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RBM22 gene promoter:
         AML1a   Sp1   XBP-1   NF-kappaB   E4BP4   PPAR-gamma1   PPAR-gamma2   NF-kappaB1   MRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRBM22 promoter sequence
   Search SABiosciences Chromatin IP Primers for RBM22

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RBM22


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q33.1   Ensembl cytogenetic band:  5q33.1   HGNC cytogenetic band: 5q33.1

RBM22 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RBM22 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M150050:  view genomic region     (about GC identifiers)

Start:
150,070,352 bp from pter      End:
150,080,669 bp from pter
Size:
10,318 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RBM22_HUMAN, Q9NW64 (See protein sequence)
Recommended Name: Pre-mRNA-splicing factor RBM22  
Size: 420 amino acids; 46896 Da
Subunit: Identified in the spliceosome C complex. Interacts with PDCD6; the interaction induces translocation of
PDCD6 in the cytoplasm
Subcellular location: Nucleus. Cytoplasm. Note=Mainly located in the nucleus. Translocated from the nucleus to the
cytoplasm after heat shock cell treatment. May be shuttling between the nucleus and the cytosol
Sequence caution: Sequence=AAC99998.1; Type=Miscellaneous discrepancy; Note=Chimera;
1 PDB 3D structure from and Proteopedia for RBM22:
2YTC (3D)    
Secondary accessions: A6NDM5 B4DLI9 O95607
Alternative splicing: 2 isoforms:  Q9NW64-1   Q9NW64-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RBM22: NX_Q9NW64

Explore proteomics data for RBM22 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NW64

  • RBM22 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RBM22 Protein Expression
    REFSEQ proteins: NP_060517.1  
    ENSEMBL proteins: 
     ENSP00000199814   ENSP00000412118   ENSP00000428154   ENSP00000430946   ENSP00000441594  

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    Cloud-Clone Corp. Proteins for RBM22 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0071013catalytic step 2 spliceosome IDA11991638

    RBM22 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ZC3H: Zinc fingers, CCCH-type domain containing
    RBM: RNA binding motif (RRM) containing

    3 InterPro protein domains:
     IPR000571 Znf_CCCH
     IPR012677 Nucleotide-bd_a/b_plait
     IPR000504 RRM_dom

    Graphical View of Domain Structure for InterPro Entry Q9NW64

    ProtoNet protein and cluster: Q9NW64

    2 Blocks protein domains:
    IPB000504 RNA-binding region RNP-1 (RNA recognition motif)
    IPB000571 Zn-finger


    UniProtKB/Swiss-Prot: RBM22_HUMAN, Q9NW64
    Domain: The C-terminus RRM domain and the zinc finger motif are necessary for RNA-binding (By similarity)
    Similarity: Belongs to the SLT11 family
    Similarity: Contains 1 C3H1-type zinc finger
    Similarity: Contains 1 RRM (RNA recognition motif) domain


    RBM22 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RBM22_HUMAN, Q9NW64
    Function: Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain
    of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of
    the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic
    calcium-binding protein PDCD6 to the nucleus upon cellular stress responses

         Gene Ontology (GO): 5/9 molecular function terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding ----
    GO:0005487nucleocytoplasmic transporter activity IDA--
    GO:0008270zinc ion binding ----
         
    RBM22 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for RBM22:
     Decreased Wnt reporter activit  Increased HPV18 LCR reporter a  Increased gamma-H2AX phosphory 

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    SwitchGear 3'UTR luciferase reporter plasmidRBM22 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for RBM22 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1mRNA Splicing - Major Pathway
    Spliceosome0.31

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1         Kegg Pathway  (Kegg details for RBM22):
        Spliceosome


    RBM22 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RBM22

    STRING Interaction Network Preview (showing 5 interactants - click image to see 21)

    5/30 Interacting proteins for RBM22 (Q9NW641, 2, 3 ENSP000001998144) via UniProtKB, MINT, STRING, and/or I2D (see all 30)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PRNPP041561, 3EBI-2602260,EBI-977302 I2D: score=1 
    MAP1LC3AQ9H4923, ENSP000003639704I2D: score=1 STRING: ENSP00000363970
    RBFOX2O432512, ENSP000004130354MINT-8337035 STRING: ENSP00000413035
    HNRNPUL1Q9BUJ22, ENSP000003758634MINT-8337013 STRING: ENSP00000375863
    AQRO603062, ENSP000001564714MINT-8337002 STRING: ENSP00000156471
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000060protein import into nucleus, translocation IDA17045351
    GO:0000398mRNA splicing, via spliceosome IC11991638
    GO:0033120positive regulation of RNA splicing IDA--
    GO:0033554cellular response to stress ----
    GO:0035690cellular response to drug IDA--

    RBM22 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RBM22

    Search CenterWatch for drugs/clinical trials and news about RBM22

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RBM22 gene: 
    NM_018047.2  

    Unigene Cluster for RBM22:

    RNA binding motif protein 22
    Hs.713564  [show with all ESTs]
    Unigene Representative Sequence: NM_018047
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000520132 ENST00000199814(uc003lst.3) ENST00000447771 ENST00000522469
    ENST00000518917 ENST00000521248 ENST00000521594 ENST00000521464 ENST00000540000

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    hsa-miR-3164 hsa-miR-181c hsa-miR-522 hsa-miR-134 hsa-miR-944 hsa-miR-10b* hsa-miR-548x hsa-miR-3118
    SwitchGear 3'UTR luciferase reporter plasmidRBM22 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AK001152.1 AK297019.1 AL136933.1 BC003402.1 

    12 DOTS entries:

    DT.453686  DT.100788221  DT.97856089  DT.92437478  DT.97781976  DT.70103058  DT.100656143  DT.120813644 
    DT.40132255  DT.120813639  DT.91641600  DT.97807821 

    24/239 AceView cDNA sequences (see all 239):

    AL044656 CA392137 AU135503 AW135771 CA412445 BG230629 AI337352 BU681327 
    AA740988 CA312338 BU170445 AL538762 AW771109 N46678 CD368539 CA314579 
    BM714584 BQ218028 BU607915 BQ772802 CA428134 BX102718 AA662903 BE894562 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for RBM22    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11
    SP1:                                                  -     -                           
    SP2:                                                                                    
    SP3:                                                                                    
    SP4:                                                                                    


    ECgene alternative splicing isoforms for RBM22

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RBM22 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAATTACTGT
    RBM22 Expression
    About this image


    See RBM22 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RBM22

    SOURCE GeneReport for Unigene cluster: Hs.713564
        SABiosciences Custom PCR Arrays for RBM22
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RBM22 gene from 10/26 species (see all 26)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rbm221 , 5 RNA binding motif protein 221, 5 90(n)1
    100(a)1
      18 (34.36 cM)5
    668101  NM_025776.21  NP_080052.11 
     605607365 
    chicken
    (Gallus gallus)
    Aves RBM221 RNA binding motif protein 22 82.94(n)
    97.14(a)
      416270  NM_001006151.1  NP_001006151.1 
    lizard
    (Anolis carolinensis)
    Reptilia RBM226
    Uncharacterized protein
    98(a)
    1 ↔ 1
    2(138447584-138458949)
    African clawed frog
    (Xenopus laevis)
    Amphibia cg14641-prov2 hypothetical protein MGC53757 78.57(n)    BC045067.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufc62e032 wufc62e03 79.09(n)   325253  CF265658.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG146411 CG14641 62.33(n)
    63.78(a)
      40529  NM_141183.3  NP_649440.3 
    worm
    (Caenorhabditis elegans)
    Secernentea T11G6.81 Protein T11G6.8 57.77(n)
    55.7(a)
      177979  NM_069613.4  NP_502014.2 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes ECM2(YBR065C)4 Pre-mRNA splicing factor, facilitates the cooperative more   --   2(369678-368584) 852357  NP_009621.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G295801 zinc finger CCCH domain-containing protein 25 57.08(n)
    53.97(a)
      817507  NM_128511.1  NP_180518.1 
    rice
    (Oryza sativa)
    Liliopsida Os.143142 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 73.98(n)    AK120360.1 


    ENSEMBL Gene Tree for RBM22 (if available)
    TreeFam Gene Tree for RBM22 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RBM22 gene

    RBM22 for paralogs           About GeneDecksing


    5/15 Pseudogenes.org Pseudogenes for RBM22 (see all 15)
    PGOHUM00000248351 PGOHUM00000249060 PGOHUM00000249066 PGOHUM00000234908 PGOHUM00000243630


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/303 SNPs in RBM22 are shown (see all 303)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1399274381,2
    --150069854(+) ATAATA/GAATGT 1 -- ds50010--------
    rs798340761,2
    C,F--150069993(+) AGTAGC/TTGGCA 1 -- ds50012Minor allele frequency- T:0.01WA NA 238
    rs1823815511,2
    --150070003(+) ACTATC/TGGCAT 1 -- ds50010--------
    rs1130303531,2
    C--150070127(+) TAAAT-/AACTAA 1 -- ds50011Minor allele frequency- A:0.50CSA 2
    rs1454483401,2
    --150070185(+) CTGAGA/GTTAAA 1 -- ds50010--------
    rs1890639121,2
    --150070253(+) AAAAAC/TTTACA 1 -- ds50010--------
    rs2008428091,2
    --150070346(+) CCATG-/ACAACATG 1 -- ds50010--------
    rs1452858421,2
    --150070744(+) TCAGAG/TTCCTT 1 -- ut310--------
    rs121871201,2
    H--150070893(+) TTTTTA/TAGATG 1 -- ut311Minor allele frequency- T:0.00NS 120
    rs1477888601,2
    C--150070949(+) TTTTA-/CTGCAGGT 1 -- cds10--------

    HapMap Linkage Disequilibrium report for RBM22 (150070352 - 150080669 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for RBM22:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv29484CNV Loss19812545
    nsv428129CNV Loss18775914
    esv33898CNV Loss17666407
    dgv1862e1CNV Complex17122850

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    RBM22 for disorders           About MalaCards
    OMIM gene information: 612430    OMIM disorders: --


    RBM22 for disorders           About GeneDecksing


    Export disorders for RBM22 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RBM22 gene, integrated from 9 sources (see all 33):
    (articles sorted by number of sources associating them with RBM22)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The influence of calcium signaling on the regulation of alternative splicing. (PubMed id 19133299)1, 2, 3 Krebs J. (2008)
    2. Cwc2 and its human homologue RBM22 promote an active conformation of the spliceosome catalytic centre. (PubMed id 22246180)1, 2 Rasche N....Luhrmann R. (2012)
    3. RNA-binding motif protein RBM22 is required for norma l development of zebrafish embryos. (PubMed id 20013661)1, 3 He F....Gou L.T. (2009)
    4. Nuclear translocation of the calcium-binding protein ALG-2 induced by the RNA-binding protein RBM22. (PubMed id 17045351)1, 2 Montaville P.... Krebs J. (2006)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. (PubMed id 11991638)1, 2 Jurica M.S.... Moore M.J. (2002)
    8. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
    9. Transcriptional map of the Treacher Collins candidate gene region. (PubMed id 8681136)1, 2 Loftus S.K.... Wasmuth J.J. (1996)
    10. The functional interactome landscape of the human hist one deacetylase family. (PubMed id 23752268)1 Joshi P....Cristea I.M. (2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55696 HGNC: 25503 AceView: RBM22 Ensembl:ENSG00000086589 euGenes: HUgn55696
    ECgene: RBM22 Kegg: 55696 H-InvDB: RBM22

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RBM22 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RBM22 gene:
    Search GeneIP for patents involving RBM22

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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