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Aliases for RBM18 Gene

Aliases for RBM18 Gene

  • RNA Binding Motif Protein 18 2 3 5
  • RNA-Binding Motif Protein 18 4

External Ids for RBM18 Gene

Previous GeneCards Identifiers for RBM18 Gene

  • GC09M120378
  • GC09M122081
  • GC09M124041
  • GC09M125001
  • GC09M094616

Summaries for RBM18 Gene

GeneCards Summary for RBM18 Gene

RBM18 (RNA Binding Motif Protein 18) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and nucleotide binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RBM18 Gene

Genomics for RBM18 Gene

Regulatory Elements for RBM18 Gene

Promoters for RBM18 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around RBM18 on UCSC Golden Path with GeneCards custom track

Genomic Location for RBM18 Gene

Chromosome:
9
Start:
122,237,624 bp from pter
End:
122,264,864 bp from pter
Size:
27,241 bases
Orientation:
Minus strand

Genomic View for RBM18 Gene

Genes around RBM18 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RBM18 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RBM18 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RBM18 Gene

Proteins for RBM18 Gene

  • Protein details for RBM18 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96H35-RBM18_HUMAN
    Recommended name:
    Probable RNA-binding protein 18
    Protein Accession:
    Q96H35
    Secondary Accessions:
    • B3KQ89

    Protein attributes for RBM18 Gene

    Size:
    190 amino acids
    Molecular mass:
    21649 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RBM18 Gene

Proteomics data for RBM18 Gene at MOPED

Post-translational modifications for RBM18 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RBM18 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RBM18 Gene

Domains & Families for RBM18 Gene

Gene Families for RBM18 Gene

Protein Domains for RBM18 Gene

Suggested Antigen Peptide Sequences for RBM18 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96H35

UniProtKB/Swiss-Prot:

RBM18_HUMAN :
  • Contains 1 RRM (RNA recognition motif) domain.
Domain:
  • Contains 1 RRM (RNA recognition motif) domain.
genes like me logo Genes that share domains with RBM18: view

Function for RBM18 Gene

Gene Ontology (GO) - Molecular Function for RBM18 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
genes like me logo Genes that share ontologies with RBM18: view
genes like me logo Genes that share phenotypes with RBM18: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RBM18 Gene

Localization for RBM18 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RBM18 Gene COMPARTMENTS Subcellular localization image for RBM18 gene
Compartment Confidence
nucleus 4

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for RBM18 Gene

Pathways & Interactions for RBM18 Gene

SuperPathways for RBM18 Gene

No Data Available

Interacting Proteins for RBM18 Gene

Gene Ontology (GO) - Biological Process for RBM18 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RBM18 Gene

Drugs & Compounds for RBM18 Gene

No Compound Related Data Available

Transcripts for RBM18 Gene

Unigene Clusters for RBM18 Gene

RNA binding motif protein 18:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RBM18 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b
SP1: - - -
SP2: - -
SP3: - - - -
SP4: -
SP5: - -

Relevant External Links for RBM18 Gene

GeneLoc Exon Structure for
RBM18
ECgene alternative splicing isoforms for
RBM18

Expression for RBM18 Gene

mRNA expression in normal human tissues for RBM18 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for RBM18 Gene



SOURCE GeneReport for Unigene cluster for RBM18 Gene Hs.415842

genes like me logo Genes that share expression patterns with RBM18: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for RBM18 Gene

Orthologs for RBM18 Gene

This gene was present in the common ancestor of animals.

Orthologs for RBM18 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia RBM18 36
  • 100 (a)
OneToOne
RBM18 35
  • 99.65 (n)
  • 100 (a)
cow
(Bos Taurus)
Mammalia RBM18 35
  • 92.46 (n)
  • 98.42 (a)
RBM18 36
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia RBM18 36
  • 99 (a)
OneToOne
RBM18 35
  • 93.86 (n)
  • 99.47 (a)
mouse
(Mus musculus)
Mammalia Rbm18 36
  • 99 (a)
OneToOne
Rbm18 16
Rbm18 35
  • 93.86 (n)
  • 98.95 (a)
oppossum
(Monodelphis domestica)
Mammalia RBM18 36
  • 97 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia RBM18 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Rbm18 35
  • 91.75 (n)
  • 98.95 (a)
chicken
(Gallus gallus)
Aves RBM18 35
  • 82.98 (n)
  • 93.16 (a)
RBM18 36
  • 93 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.4447 35
tropical clawed frog
(Silurana tropicalis)
Amphibia rbm18 35
  • 73.66 (n)
  • 78.45 (a)
Str.9829 35
zebrafish
(Danio rerio)
Actinopterygii rbm18 35
  • 69.48 (n)
  • 73.6 (a)
zgc73332 35
rbm18 36
  • 69 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP012137 35
  • 48.21 (n)
  • 43.85 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG14414 35
  • 51.96 (n)
  • 41.91 (a)
CG14414 36
  • 32 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 39 (a)
OneToOne
Species with no ortholog for RBM18:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RBM18 Gene

ENSEMBL:
Gene Tree for RBM18 (if available)
TreeFam:
Gene Tree for RBM18 (if available)

Paralogs for RBM18 Gene

No data available for Paralogs for RBM18 Gene

Variants for RBM18 Gene

Sequence variations from dbSNP and Humsavar for RBM18 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1060586 -- 122,241,400(-) TACTA(C/T)GGCAA nc-transcript-variant, utr-variant-3-prime
rs1888218 -- 122,252,196(+) TCCAA(C/T)ACAAA intron-variant
rs2297177 -- 122,261,695(+) GCCAG(A/G)GCACA intron-variant
rs2297178 -- 122,261,728(+) GGGGC(A/G)TGGTT intron-variant
rs3048199 -- 122,256,067(+) aacaa(-/CAA)aaaCC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RBM18 Gene

Variant ID Type Subtype PubMed ID
nsv523017 CNV Loss 19592680
nsv416680 CNV Loss 16902084

Variation tolerance for RBM18 Gene

Residual Variation Intolerance Score: 35.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.34; 7.61% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RBM18 Gene

HapMap Linkage Disequilibrium report
RBM18

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RBM18 Gene

Disorders for RBM18 Gene

Relevant External Links for RBM18

Genetic Association Database (GAD)
RBM18
Human Genome Epidemiology (HuGE) Navigator
RBM18
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
RBM18

No disorders were found for RBM18 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RBM18 Gene

Publications for RBM18 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J. … Yang X. (Mol. Syst. Biol. 2011) 3
  5. Image-based genome-wide siRNA screen identifies selective autophagy factors. (PMID: 22020285) Orvedahl A. … Levine B. (Nature 2011) 3

Products for RBM18 Gene

Sources for RBM18 Gene

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