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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RBM15 Gene

protein-coding   GIFtS: 51
GCID: GC01P110882

RNA Binding Motif Protein 15

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
RNA Binding Motif Protein 151 2     RNA-Binding Motif Protein 152 3
OTT2 3 5     SPEN2 5
One Twenty-Two1 2     One Twenty Two Protein2
One-Twenty Two Protein 12 3     Putative RNA-Binding Protein 152
OTT12 3     

External Ids:    HGNC: 149591   Entrez Gene: 647832   Ensembl: ENSG000001627757   OMIM: 6060775   UniProtKB: Q96T373   

Export aliases for RBM15 gene to outside databases

Previous GC identifers: GC01P111298 GC01P109748 GC01P109983 GC01P110179 GC01P110180 GC01P110593 GC01P110682 GC01P110876 GC01P108753


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RBM15 Gene:
Members of the SPEN (Split-end) family of proteins, including RBM15, have repressor function in several signaling
pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 (PubMed
16129689)).(supplied by OMIM, Feb 2009)

GeneCards Summary for RBM15 Gene: 
RBM15 (RNA binding motif protein 15) is a protein-coding gene. Diseases associated with RBM15 include pancreatic cystadenoma, and microcystic adenoma. GO annotations related to this gene include RNA binding and nucleotide binding. An important paralog of this gene is RBM15B.

UniProtKB/Swiss-Prot: RBM15_HUMAN, Q96T37
Function: May be implicated in HOX gene regulation

Gene Wiki entry for RBM15 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_032977.9  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RBM15 gene promoter:
         Egr-2   Egr-3   TBP   SRY   Ik-2   Egr-1   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   POU3F2   C/EBPalpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRBM15 promoter sequence
   Search SABiosciences Chromatin IP Primers for RBM15

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RBM15


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p13   Ensembl cytogenetic band:  1p13.3   HGNC cytogenetic band: 1p13

RBM15 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RBM15 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P110882:  view genomic region     (about GC identifiers)

Start:
110,881,128 bp from pter      End:
110,889,303 bp from pter
Size:
8,176 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RBM15_HUMAN, Q96T37 (See protein sequence)
Recommended Name: Putative RNA-binding protein 15  
Size: 977 amino acids; 107189 Da
Subunit: Interacts with Epstein-Barr virus BSFL2/BMLF1
Subcellular location: Nucleus
Sequence caution: Sequence=BAB14088.1; Type=Erroneous initiation; Sequence=BAB15185.1; Type=Erroneous initiation;
Secondary accessions: Q4V760 Q5D058 Q5T613 Q96PE4 Q96SC5 Q96SC6 Q96SC9 Q96SD0 Q96T38 Q9BRA5
Q9H6R8 Q9H9Y0
Alternative splicing: 3 isoforms:  Q96T37-1   Q96T37-2   Q96T37-3   

Explore the universe of human proteins at neXtProt for RBM15: NX_Q96T37

Explore proteomics data for RBM15 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96T37

  • RBM15 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RBM15 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001188474.1  NP_073605.4  

    ENSEMBL proteins: 
     ENSP00000358799   ENSP00000473638   ENSP00000473552  

    Human Recombinant Protein Products for RBM15: 
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    Novus Biologicals RBM15 Protein
    Novus Biologicals RBM15 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for RBM15 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--

    RBM15 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    RBM: RNA binding motif (RRM) containing

    5 InterPro protein domains:
     IPR012921 SPOC_C
     IPR012677 Nucleotide-bd_a/b_plait
     IPR010912 SPOC_met
     IPR016194 SPOC_like_C_dom
     IPR000504 RRM_dom

    Graphical View of Domain Structure for InterPro Entry Q96T37

    ProtoNet protein and cluster: Q96T37

    2 Blocks protein domains:
    IPB000504 RNA-binding region RNP-1 (RNA recognition motif)
    IPB012921 SPOC


    UniProtKB/Swiss-Prot: RBM15_HUMAN, Q96T37
    Similarity: Belongs to the RRM Spen family
    Similarity: Contains 3 RRM (RNA recognition motif) domains
    Similarity: Contains 1 SPOC domain


    RBM15 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RBM15_HUMAN, Q96T37
    Function: May be implicated in HOX gene regulation

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding IEA--
    GO:0005515protein binding IPI16129689
         
    RBM15 for ontologies           About GeneDecksing


    Phenotypes:
         4 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Rbm15):
     cellular  hematopoietic system  immune system  mortality/aging 

    RBM15 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Rbm15tm1.1Dgg for RBM15

       inGenious Targeting Laboratory - Custom generated mouse model solutions for RBM15 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for RBM15

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RBM15 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RBM15 

    miRNA
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    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate RBM15 (see all 13):
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    SwitchGear 3'UTR luciferase reporter plasmidRBM15 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBM15


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RBM15

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/618 Interacting proteins for RBM15 (Q96T372, 3 ENSP000003587994) via UniProtKB, MINT, STRING, and/or I2D (see all 618)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAPK8P459832, 3, ENSP000003534834MINT-8262341 I2D: score=2 STRING: ENSP00000353483
    MAP1LC3AQ9H4923, ENSP000003639704I2D: score=2 STRING: ENSP00000363970
    HDAC3O153793, ENSP000003029674I2D: score=1 STRING: ENSP00000302967
    SUMO1P631653, ENSP000003760764I2D: score=1 STRING: ENSP00000376076
    UPF1Q929002, ENSP000002628034MINT-7945693 STRING: ENSP00000262803
    About this table

    Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter ----
    GO:0001569patterning of blood vessels IEA--
    GO:0007221positive regulation of transcription of Notch receptor target IEA--
    GO:0019048modulation by virus of host morphology or physiology IEA--
    GO:0045638negative regulation of myeloid cell differentiation IEA--

    RBM15 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RBM15

    Search CenterWatch for drugs/clinical trials and news about RBM15

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RBM15 gene (2 alternative transcripts): 
    NM_001201545.1  NM_022768.4  

    Unigene Clusters for RBM15:

    RNA binding motif protein 15
    Hs.435947  [show with all ESTs], Hs.708172  [show with all ESTs]
    Unigene Representative Sequences: BC042587, AB209680
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000369784(uc001dzl.1 uc001dzm.1) ENST00000602849 ENST00000487146

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RBM15
    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate RBM15 (see all 13):
    hsa-miR-22 hsa-miR-520a-5p hsa-miR-373* hsa-miR-583 hsa-miR-3692 hsa-miR-942 hsa-miR-320e hsa-miR-581
    SwitchGear 3'UTR luciferase reporter plasmidRBM15 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RBM15
    Sirion Biotech Customized lentivirus for stable overexpression of RBM15 
                         Customized lentivirus expression plasmids for stable overexpression of RBM15 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for RBM15
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RBM15
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RBM15

    Additional mRNA sequence: 

    AB209680.1 BC069656.1 BC069701.1 BC069719.1 BC069739.1 BC069755.1 

    7 DOTS entries:

    DT.87016432  DT.211537  DT.75103092  DT.97768794  DT.100658991  DT.100680563  DT.95276844 

    24/60 AceView cDNA sequences (see all 60):

    BE221286 CB529546 AI634112 BF448359 AI869382 BC062316 AI093558 BC042587 
    BU685828 BC006397 AI478458 AF086464 BX101314 BE505017 BE222623 AI375793 
    NM_022768 AI871508 BG760350 AA977671 AI217723 BC047479 AI458718 AI270519 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RBM15 expression in normal human tissues (normalized intensities)      RBM15 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGCCTCTGAT
    RBM15 Expression
    About this image


    RBM15 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/26 selected tissues (see all 26) fully expand
     
     Colon (Gastrointestinal Tract)    fully expand to see all 4 entries
             colon ; peripheral nerve/ganglion   
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Epithelium (Reproductive System)    fully expand to see all 4 entries
             cervix, uterine ; squamous epithelial cells   
     
     Blood (Hematopoietic System)    fully expand to see all 2 entries
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
             lung ; macrophages   
     
     Uterus
             cervix, uterine ; glandular cells   

    See RBM15 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RBM15

    SOURCE GeneReport for Unigene clusters: Hs.435947 Hs.708172
        SABiosciences Custom PCR Arrays for RBM15
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBM15

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for RBM15 gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rbm151 , 5 RNA binding motif protein 151, 5 90.32(n)1
    95.09(a)1
      3 (46.83 cM)5
    2297001  NM_001045807.11  NP_001039272.11 
     1073261105 
    chicken
    (Gallus gallus)
    Aves LOC1008595951 putative RNA-binding protein 15-like 71.46(n)
    79.47(a)
      100859595  XM_003642736.1  XP_003642784.1 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.195052 Xenopus laevis transcribed sequence with weak similarity more 74.81(n)    AW638365.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.154902 Transcribed sequence with moderate similarity to protein more 75.55(n)    CK238148.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta nito1 spenito 48.29(n)
    43.31(a)
      35756  NM_136495.2  NP_610339.1 
    worm
    (Caenorhabditis elegans)
    Secernentea grld-11 Protein GRLD-1 44.49(n)
    32.6(a)
      176827  NM_171237.4  NP_741283.1 


    ENSEMBL Gene Tree for RBM15 (if available)
    TreeFam Gene Tree for RBM15 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RBM15 gene
    RBM15B2  SPEN2  
    1 SIMAP similar gene for RBM15 using alignment to 4 protein entries:     RBM15_HUMAN (see all proteins):
    RBM15B

    RBM15 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for RBM15
    PGOHUM00000251332


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/121 SNPs in RBM15 are shown (see all 121)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2014337181,2
    C--110883852(+) CTTACA/GAGCCA 4 K E mis10--------
    rs37387511,2
    C,F,H--110883917(-) AGATCT/CCGATC 4 /R syn121Minor allele frequency- C:0.07EA NA NS EU 9451
    rs1509003311,2
    C,F--110884030(+) CTGCGC/TTCCTT 4 A V mis12Minor allele frequency- T:0.00NA EU 5875
    rs1379443961,2
    C,F--110884068(+) GTAGCC/AGGGAT 4 /R syn11Minor allele frequency- A:0.00NA 4550
    rs1827192651,2
    --110884168(+) CCAGGG/TTGACA 4 G V mis10--------
    rs1873676671,2
    C--110884346(+) GGGGGA/GACAGC 4 G syn10--------
    rs1922485791,2
    C--110884348(+) GGGGAC/TAGCCC 4 T I mis10--------
    rs617452921,2
    C,F--110884493(+) TCAACT/CGGAGG 4 /T syn14Minor allele frequency- C:0.03NS CSA WA NA 4742
    rs2013426571,2
    --110884626(+) GAAGTC/TCTGAC 4 P S mis10--------
    rs759615951,2
    C--110884630(+) TTCTGA/CCAGCC 4 D A mis10--------

    HapMap Linkage Disequilibrium report for RBM15 (110881128 - 110889303 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for RBM15: --

    Human Gene Mutation Database (HGMD): RBM15
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing RBM15
    DNA2.0 Custom Variant and Variant Library Synthesis for RBM15

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606077    OMIM disorders: --

    UniProtKB/Swiss-Prot: RBM15_HUMAN, Q96T37
  • Note=A chromosomal aberration involving RBM15 may be a cause of acute megakaryoblastic leukemia.
    Translocation t(1;22)(p13;q13) with MKL1. Although both reciprocal fusion transcripts are detected in acute
    megakaryoblastic leukemia (AMKL, FAB-M7), the RBM15-MKL1 chimeric protein has all the putative functional domains
    encoded by each gene and is the candidate oncogene

  • 11 diseases for RBM15:    About MalaCards
    pancreatic cystadenoma    microcystic adenoma    megakaryocytic leukemia    cystadenoma
    kaposi's sarcoma    acute myeloid leukemia    adenoma    sarcoma
    myeloid leukemia    leukemia    pancreatitis

    1 disease from the University of Copenhagen DISEASES database for RBM15:
    Megakaryocytic leukemia

    RBM15 for disorders           About GeneDecksing


    Export disorders for RBM15 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RBM15 gene, integrated from 9 sources (see all 42):
    (articles sorted by number of sources associating them with RBM15)
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    1. Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia. (PubMed id 11431691)1, 2, 3, 9 Ma Z.... Hitzler J.K. (2001)
    2. Involvement of a human gene related to the Drosophila spen gene in the recurrent t(1;22) translocation of acute megakaryocytic leukemia. (PubMed id 11344311)1, 2, 3 Mercher T....Bernard O.A. (2001)
    3. Interaction of the Epstein-Barr virus mRNA export factor EB2 with human Spen proteins SHARP, OTT1, and a novel member of the family, OTT3, links Spen proteins with splicing regulation and mRNA export. (PubMed id 16129689)1, 2, 9 Hiriart E.... Manet E. (2005)
    4. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
    5. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    6. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    9. The RNA-binding motif protein 15B (RBM15B/OTT3) acts as cofactor of the nuclear export receptor NXF1. (PubMed id 19586903)1, 9 Uranishi H....Felber B.K. (2009)
    10. The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells. (PubMed id 23667531)1 Cox J.L....Rizzino A. (2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 64783 HGNC: 14959 AceView: RBM15 Ensembl:ENSG00000162775 euGenes: HUgn64783
    ECgene: RBM15 H-InvDB: RBM15

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RBM15 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RBM15 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RBM15 gene:
    Search GeneIP for patents involving RBM15

    GeneCards and IP:
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