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Aliases for RBM14-RBM4 Gene

Aliases for RBM14-RBM4 Gene

  • RBM14-RBM4 Readthrough 2 3 5
  • Transcriptional Coactivator CoAZ 3
  • RBM14/RBM4 Fusion 3
  • COAZ 3

External Ids for RBM14-RBM4 Gene

Previous GeneCards Identifiers for RBM14-RBM4 Gene

  • GC11U901759
  • GC11P066388

Summaries for RBM14-RBM4 Gene

Entrez Gene Summary for RBM14-RBM4 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring RBM14 (RNA binding motif protein 14) and RBM4 (RNA binding motif protein 4) genes. Alternative splicing results in multiple transcript variants, one of which encodes a fusion protein that shares sequence identity with each individual gene product. This fusion protein contains RRM and zinc finger domains, and it functions to stimulate transcription in a hormone and receptor-dependent manner. [provided by RefSeq, Nov 2010]

GeneCards Summary for RBM14-RBM4 Gene

RBM14-RBM4 (RBM14-RBM4 Readthrough) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is RBM14.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RBM14-RBM4 Gene

Genomics for RBM14-RBM4 Gene

Regulatory Elements for RBM14-RBM4 Gene

Promoters for RBM14-RBM4 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around RBM14-RBM4 on UCSC Golden Path with GeneCards custom track

Genomic Location for RBM14-RBM4 Gene

66,616,582 bp from pter
66,646,473 bp from pter
29,892 bases
Plus strand

Genomic View for RBM14-RBM4 Gene

Genes around RBM14-RBM4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RBM14-RBM4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RBM14-RBM4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RBM14-RBM4 Gene

Proteins for RBM14-RBM4 Gene

  • Protein details for RBM14-RBM4 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    Protein RBM14-RBM4
    Protein Accession:

    Protein attributes for RBM14-RBM4 Gene

    147 amino acids
    Molecular mass:
    15972 Da
    Quaternary structure:
    No Data Available
  • Protein details for RBM14-RBM4 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    Protein RBM14-RBM4
    Protein Accession:

    Protein attributes for RBM14-RBM4 Gene

    118 amino acids
    Molecular mass:
    12894 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RBM14-RBM4 Gene

Proteomics data for RBM14-RBM4 Gene at MOPED

Post-translational modifications for RBM14-RBM4 Gene

No Post-translational modifications

Other Protein References for RBM14-RBM4 Gene

No data available for DME Specific Peptides for RBM14-RBM4 Gene

Domains & Families for RBM14-RBM4 Gene

Protein Domains for RBM14-RBM4 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RBM14-RBM4: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RBM14-RBM4 Gene

Function for RBM14-RBM4 Gene

Gene Ontology (GO) - Molecular Function for RBM14-RBM4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
genes like me logo Genes that share ontologies with RBM14-RBM4: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RBM14-RBM4 Gene

Localization for RBM14-RBM4 Gene

Subcellular locations from

Jensen Localization Image for RBM14-RBM4 Gene COMPARTMENTS Subcellular localization image for RBM14-RBM4 gene
Compartment Confidence
nucleus 5

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for RBM14-RBM4 Gene

Pathways & Interactions for RBM14-RBM4 Gene

SuperPathways for RBM14-RBM4 Gene

No Data Available

Interacting Proteins for RBM14-RBM4 Gene

Gene Ontology (GO) - Biological Process for RBM14-RBM4 Gene


No data available for Pathways by source and SIGNOR curated interactions for RBM14-RBM4 Gene

Drugs & Compounds for RBM14-RBM4 Gene

No Compound Related Data Available

Transcripts for RBM14-RBM4 Gene

mRNA/cDNA for RBM14-RBM4 Gene

(2) REFSEQ mRNAs :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RBM14-RBM4 Gene

No ASD Table

Relevant External Links for RBM14-RBM4 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RBM14-RBM4 Gene

mRNA expression in normal human tissues for RBM14-RBM4 Gene

genes like me logo Genes that share expression patterns with RBM14-RBM4: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for RBM14-RBM4 Gene

Orthologs for RBM14-RBM4 Gene

This gene was present in the common ancestor of animals.

Orthologs for RBM14-RBM4 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia RBM4 36
  • 72 (a)
(Canis familiaris)
Mammalia -- 36
  • 74 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 69 (a)
(Mus musculus)
Mammalia Gm21992 36
  • 55 (a)
Rbm4 36
  • 73 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 66 (a)
(Pan troglodytes)
Mammalia RBM4 36
  • 75 (a)
(Gallus gallus)
Aves -- 36
  • 53 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 52 (a)
(Danio rerio)
Actinopterygii rbm4.1 36
  • 34 (a)
rbm4.2 36
  • 34 (a)
rbm4.3 36
  • 34 (a)
zgc:77262 36
  • 28 (a)
fruit fly
(Drosophila melanogaster)
Insecta lark 36
  • 28 (a)
(Caenorhabditis elegans)
Secernentea rnp-1 36
  • 20 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 19 (a)
Species with no ortholog for RBM14-RBM4:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for RBM14-RBM4 Gene

Gene Tree for RBM14-RBM4 (if available)
Gene Tree for RBM14-RBM4 (if available)

Paralogs for RBM14-RBM4 Gene

Paralogs for RBM14-RBM4 Gene

genes like me logo Genes that share paralogs with RBM14-RBM4: view

Variants for RBM14-RBM4 Gene

Sequence variations from dbSNP and Humsavar for RBM14-RBM4 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs535211 -- 66,633,009(-) AATAA(A/G)AGATG intron-variant
rs566673 -- 66,633,902(-) GGCCA(A/C)TTAAA intron-variant
rs580910 -- 66,634,862(-) ATACT(A/G)GCCTT intron-variant
rs1783468 -- 66,634,155(-) tgagg(C/T)cggga intron-variant
rs1783469 -- 66,634,154(-) gaggt(C/T)gggag intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RBM14-RBM4 Gene

Variant ID Type Subtype PubMed ID
nsv522277 CNV Loss 19592680
nsv363 CNV Insertion 18451855
nsv897789 CNV Gain 21882294
nsv518919 CNV Loss 19592680
esv990794 OTHER Inversion 20482838

Variation tolerance for RBM14-RBM4 Gene

Residual Variation Intolerance Score: 9.39% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.47; 10.30% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for RBM14-RBM4 Gene

Disorders for RBM14-RBM4 Gene

Relevant External Links for RBM14-RBM4

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for RBM14-RBM4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RBM14-RBM4 Gene

Publications for RBM14-RBM4 Gene

  1. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface. (PMID: 26638075) Gupta G.D. … Pelletier L. (Cell 2015) 3
  4. The central role of EED in the orchestration of polycomb group complexes. (PMID: 24457600) Cao Q. … Chinnaiyan A.M. (Nat Commun 2014) 3
  5. Identifying biological pathways that underlie primordial short stature using network analysis. (PMID: 24711643) Hanson D. … Clayton P.E. (J. Mol. Endocrinol. 2014) 3

Products for RBM14-RBM4 Gene

Sources for RBM14-RBM4 Gene