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RBM14 Gene

protein-coding   GIFtS: 52
GCID: GC11P066384

RNA Binding Motif Protein 14

  See RBM14-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RNA Binding Motif Protein 141 2     Coactivator Activator1
PSP22 3 5     SYT Interacting Protein1
SIP2 3 5     SYTIP12
Paraspeckle Protein 22 3     TMEM1372
Synaptotagmin-Interacting Protein2 3     RNA-Binding Protein 142
RRM-Containing Coactivator Activator/Modulator2 3     Transmembrane Protein 1372
SYT-Interacting Protein2 3     RNA-Binding Motif Protein 143
COAA2 5     

External Ids:    HGNC: 142191   Entrez Gene: 104322   Ensembl: ENSG000002393067   OMIM: 6124095   UniProtKB: Q96PK63   

Export aliases for RBM14 gene to outside databases

Previous GC identifers: GC11P068918 GC11P068065 GC11P066634 GC11P066159 GC11P066140 GC11P062712


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RBM14 Gene:
This gene encodes a ribonucleoprotein that functions as a general nuclear coactivator, and an RNA splicing
modulator. This protein contains two RNA recognition motifs (RRM) at the N-terminus, and multiple hexapeptide
repeat domain at the C-terminus that interacts with thyroid hormone receptor-binding protein (TRBP), and is
required for transcription activation. Alternatively spliced transcript variants encoding different isoforms
(with opposing effects on transcription) have been described for this gene. (provided by RefSeq, Oct 2011)

GeneCards Summary for RBM14 Gene:
RBM14 (RNA binding motif protein 14) is a protein-coding gene. Diseases associated with RBM14 include lipogranulomatosis, and farber lipogranulomatosis. GO annotations related to this gene include RNA binding and protein binding, bridging. An important paralog of this gene is RBM4.

UniProtKB/Swiss-Prot: RBM14_HUMAN, Q96PK6
Function: Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other
coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating
transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1

Gene Wiki entry for RBM14 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NC_018922.2  NT_167190.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RBM14 gene promoter:
         NF-1/L   NF-1   XBP-1   CUTL1   AREB6   FAC1   HOXA5   c-Myb   NF-Y   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): RBM14 promoter sequence
   Search Chromatin IP Primers for RBM14

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RBM14


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q13.2   Ensembl cytogenetic band:  11q13.2   HGNC cytogenetic band: 11q13.2

RBM14 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RBM14 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P066384:  view genomic region     (about GC identifiers)

Start:
66,384,053 bp from pter      End:
66,397,405 bp from pter
Size:
13,353 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RBM14_HUMAN, Q96PK6 (See protein sequence)
Recommended Name: RNA-binding protein 14  
Size: 669 amino acids; 69492 Da
Subunit: Isoform 1 interacts with NCOA6, CITED1 and XRCC5/KU86. Isoform 1 interacts with SS18 isoform 1. Isoform 1
interacts with SS18 isoform 2
1 PDB 3D structure from and Proteopedia for RBM14:
2DNP (3D)    
Secondary accessions: B0LM41 B3KMN4 D6RGD8 O75932 Q2PYN1 Q53GV1 Q68DQ9 Q96PK5
Alternative splicing: 5 isoforms:  Q96PK6-1   Q96PK6-2   Q96PK6-3   Q96PK6-4   Q96PK6-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RBM14: NX_Q96PK6

Explore proteomics data for RBM14 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys135
  • Modification sites at PhosphoSitePlus

  • See RBM14 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001185765.1  NP_001185766.1  NP_006319.1  

    ENSEMBL proteins: 
     ENSP00000311747   ENSP00000377548   ENSP00000386518   ENSP00000414650   ENSP00000386995  

    RBM14 Human Recombinant Protein Products:

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    Browse Proteins at Cloud-Clone Corp.

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RBM: RNA binding motif (RRM) containing

    2 InterPro protein domains:
     IPR012677 Nucleotide-bd_a/b_plait
     IPR000504 RRM_dom

    Graphical View of Domain Structure for InterPro Entry Q96PK6

    ProtoNet protein and cluster: Q96PK6

    1 Blocks protein domain: IPB000504 RNA-binding region RNP-1 (RNA recognition motif)

    UniProtKB/Swiss-Prot: RBM14_HUMAN, Q96PK6
    Similarity: Contains 2 RRM (RNA recognition motif) domains


    Find genes that share domains with RBM14           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RBM14_HUMAN, Q96PK6
    Function: Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other
    coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating
    transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1

         Gene Ontology (GO): Selected molecular function terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0001104RNA polymerase II transcription cofactor activity NAS11443112
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding NAS11443112
    GO:0005515protein binding IPI15919756
         
    Find genes that share ontologies with RBM14           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for RBM14:
     Decreased influenza A virus in  Decreased viability 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RBM14
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    miRNA
    Products:
        
    miRTarBase miRNAs that target RBM14:
    hsa-mir-30c-5p (MIRT047979), hsa-mir-30b-5p (MIRT046161), hsa-let-7e-5p (MIRT051521), hsa-mir-92b-3p (MIRT040655)

    Block miRNA regulation of human, mouse, rat RBM14 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RBM14 (see all 60):
    hsa-miR-21* hsa-miR-549 hsa-miR-328 hsa-miR-607 hsa-miR-4254 hsa-miR-650 hsa-miR-3916 hsa-miR-890
    SwitchGear 3'UTR luciferase reporter plasmidRBM14 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat RBM14

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBM14


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RBM14_HUMAN, Q96PK6: Nucleus. Nucleus, nucleolus. Note=In punctate subnuclear structures often located adjacent
    to splicing speckles, called paraspeckles
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005667transcription factor complex IPI11443112
    GO:0005730NOT nucleolus IDA--
    GO:0016592mediator complex NAS11443112
    GO:0030529ribonucleoprotein complex TAS11443112

    Find genes that share ontologies with RBM14           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RBM14
    Interactions:

        GeneGlobe Interaction Network for RBM14

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RBM14 (Q96PK62, 3 ENSP000003117474) via UniProtKB, MINT, STRING, and/or I2D (see all 750)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PARP1P098742, 3, ENSP000003557594MINT-8395092 I2D: score=3 STRING: ENSP00000355759
    NSFP464592, 3MINT-7945693 I2D: score=1 
    PRKAG1P546192, 3MINT-7945693 I2D: score=1 
    ENSG00000206454Q018603I2D: score=1 
    ENSG00000229094Q018603I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006260DNA replication NAS11443112
    GO:0006281DNA repair NAS11443112
    GO:0006310DNA recombination NAS11443112
    GO:0006366transcription from RNA polymerase II promoter NAS11443112
    GO:0009725response to hormone TAS11443112

    Find genes that share ontologies with RBM14           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RBM14



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RBM14 gene (4 alternative transcripts): 
    NM_001198836.1  NM_001198837.1  NM_006328.3  NM_032886.2  

    Unigene Cluster for RBM14:

    RNA binding motif protein 14
    Hs.533712  [show with all ESTs]
    Unigene Representative Sequence: NM_006328
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000310137(uc001oit.3 uc009yri.3 uc009yrh.3) ENST00000393979
    ENST00000512283 ENST00000409372 ENST00000443702 ENST00000409738 ENST00000460762
    ENST00000461478 ENST00000496694
    miRNA
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    Block miRNA regulation of human, mouse, rat RBM14 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RBM14 (see all 60):
    hsa-miR-21* hsa-miR-549 hsa-miR-328 hsa-miR-607 hsa-miR-4254 hsa-miR-650 hsa-miR-3916 hsa-miR-890
    SwitchGear 3'UTR luciferase reporter plasmidRBM14 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat RBM14
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    OriGene ORF clones in mouse, rat for RBM14
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    GenScript: all cDNA clones in your preferred vector (see all 3): RBM14 (NM_001198837)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RBM14
    Primer
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    OriGene qPCR primer pairs and template standards for RBM14
    OriGene qSTAR qPCR primer pairs in human, mouse for RBM14
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RBM14
      QuantiTect SYBR Green Assays in human, mouse, rat RBM14
      QuantiFast Probe-based Assays in human, mouse, rat RBM14

    Additional mRNA sequence: 

    AF080561.1 AF315632.1 AF315633.1 AK021768.1 AK222830.1 AK297907.1 AK307254.1 BC000488.2 
    BC007641.1 BC023619.2 BC024260.1 CR749306.1 DQ294957.1 

    Selected DOTS entries (see all 33):

    DT.91723102  DT.314961  DT.97857911  DT.100039087  DT.307734  DT.100651690  DT.92046576  DT.99933779 
    DT.100651685  DT.100651686  DT.120685242  DT.120685254  DT.91726818  DT.100769300  DT.95225740  DT.100651684 
    DT.100809697  DT.109989  DT.120685158  DT.120685168  DT.120685201  DT.120685204  DT.120685196  DT.120685214 

    Selected AceView cDNA sequences (see all 1146):

    AK094046 BI818673 CR611361 BM424116 AA351810 CB121977 CB142501 BX356476 
    BQ067180 CR612821 AU134124 BQ575114 AA846757 BM544692 AI953276 BE278821 
    AA330657 AI611835 BM757152 BG257575 BQ070540 BP351859 CR610008 BE464664 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RBM14 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGGGCCTTCC
    RBM14 Expression
    About this image


    RBM14 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Eye (Sensory Organs)
             Retina
     
     Thymus (Hematopoietic System)
     
     Thyroid (Endocrine System)
    RBM14 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RBM14 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.533712

    UniProtKB/Swiss-Prot: RBM14_HUMAN, Q96PK6
    Tissue specificity: Expressed in all tissues tested, including brain, heart, skeletal muscle, colon, thymus,
    spleen, kidney, liver, small intestine, placenta, lung and peripheral blood lymphocytes

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBM14

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for RBM14 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rbm141 , 5 RNA binding motif protein 141, 5 93.77(n)1
    98.36(a)1
      19 (4.11 cM)5
    562751  NM_019869.21  NP_063922.21 
     48005695 
    chicken
    (Gallus gallus)
    Aves RBM141 RNA binding motif protein 14 64.54(n)
    60.49(a)
      426080  XM_423757.4  XP_423757.4 
    lizard
    (Anolis carolinensis)
    Reptilia RBM146
    RNA binding motif protein 14
    48(a)
    1 ↔ 1
    GL344250.1(50105-63175)
    African clawed frog
    (Xenopus laevis)
    Amphibia LOC3984982 similar to RNA binding motif protein 14 74.79(n)    BC046684.1 
    zebrafish
    (Danio rerio)
    Actinopterygii rbm14b6
    rbm14a6
    RNA binding motif protein 14a
    26(a)
    25(a)
    1 ↔ many
    1 ↔ many
    7(7835606-7853891) ENSDARG00000001285
    21(26765065-26777052) ENSDARG00000012723
    fruit fly
    (Drosophila melanogaster)
    Insecta lark6
    lark
    28(a)
    1 → many
    3L(7332366-7334996)
    worm
    (Caenorhabditis elegans)
    Secernentea rnp-16
    Protein RNP-1, isoform a (rnp-1) mRNA, complete cd...
    23(a)
    1 → many
    V(12192275-12194445) WBGene00004384


    ENSEMBL Gene Tree for RBM14 (if available)
    TreeFam Gene Tree for RBM14 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RBM14 gene
    RBM42  RBM4B2  RBM14-RBM42  
    4 SIMAP similar genes for RBM14 using alignment to 3 protein entries:     RBM14_HUMAN (see all proteins):
    RBM4    RBM4B    RALY    SFRS5

    Find genes that share paralogs with RBM14           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RBM14 (see all 262)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs353702721,2
    C--62725732(+) GAAAAAA/-GAAAA 3 -- ut312Minor allele frequency- -:0.25NA CSA 4
    rs1886879741,2
    C--66302091(+) AGTGCC/TGGGAT 3 -- us2k10--------
    rs1435859791,2
    --66302116(+) ACCTCA/GCCTGG 3 -- us2k10--------
    rs1808155001,2
    --66302191(+) GTTCCA/GGGTTC 3 -- us2k10--------
    rs1858896981,2
    --66302534(+) TGATCC/TGCCCG 3 -- us2k10--------
    rs1472034601,2
    --66302582(+) CCACCA/GGGCCT 3 -- us2k10--------
    rs794271041,2
    F--66302694(+) GGCTTA/CGTTCC 3 -- us2k11Minor allele frequency- C:0.06WA 118
    rs1892032981,2
    C--66302747(+) TTTTAC/TTTATT 3 -- us2k10--------
    rs1997566101,2
    C--66302804(+) CTGTC-/TTTTTT 3 -- us2k10--------
    rs1406087701,2
    --66302848(+) CATGGA/TAGGTG 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for RBM14 (66384053 - 66397405 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for RBM14:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv363CNV Insertion18451855
    nsv522277CNV Loss19592680
    nsv897789CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612409    OMIM disorders: --

    2 diseases for RBM14:    
    About MalaCards
    lipogranulomatosis    farber lipogranulomatosis

    1 disease from the University of Copenhagen DISEASES database for RBM14:
    Farber lipogranulomatosis

    Find genes that share disorders with RBM14           About GenesLikeMe

    1 Novoseek inferred disease relationship for RBM14 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tumors 0 2 16878147 (1), 12973738 (1)

    Human Genome Epidemiology (HuGE) Navigator: RBM14 (1 document)

    Export disorders for RBM14 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RBM14 gene, integrated from 10 sources (see all 70):
    (articles sorted by number of sources associating them with RBM14)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of RRM-containing coactivator activator (CoAA) as TRBP-interacting protein, and its splice variant as a coactivator modulator (CoAM). (PubMed id 11443112)1, 2, 9 Iwasaki T.... Ko L. (J. Biol. Chem. 2001)
    2. Synovial sarcoma translocation (SYT) encodes a nuclear receptor coactivator. (PubMed id 15919756)1, 2, 9 Iwasaki T.... Chin W.W. (Endocrinology 2005)
    3. Functional pre- mRNA trans-splicing of coactivator CoAA and corepressor RBM4 during stem/progenitor cell differentiation. (PubMed id 19416963)1, 2 Brooks Y.S.... Ko L. (J. Biol. Chem. 2009)
    4. Switched alternative splicing of oncogene CoAA during embryonal carcinoma stem cell differentiation. (PubMed id 17337438)1, 2 Yang Z.... Ko L. (Nucleic Acids Res. 2007)
    5. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    7. Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. (PubMed id 15144186)1, 2 Brill L.M....Peters E.C. (Anal. Chem. 2004)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    9. The SYT protein involved in the t(X;18) synovial sarcoma translocation is a transcriptional activator localised in nuclear bodies. (PubMed id 9285794)1, 3 Brett D....Goodwin G. (Hum. Mol. Genet. 1997)
    10. Gene amplification and associated loss of 5' regulatory sequences of CoAA in human cancers. (PubMed id 16878147)1, 9 Sui Y....Ko L. (Oncogene 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10432 HGNC: 14219 AceView: RBM4andRBM14andLOC440048 Ensembl:ENSG00000239306 euGenes: HUgn10432
    ECgene: RBM14 H-InvDB: RBM14

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for RBM14 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RBM14 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for RBM14 gene:
    Search GeneIP for patents involving RBM14

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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