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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RBM10 Gene

protein-coding   GIFtS: 60
GCID: GC0XP047004

RNA Binding Motif Protein 10

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
RNA Binding Motif Protein 101 2     RNA-Binding Protein S1-12 3
DXS8237E2 3 5     TARPS2 5
G Patch Domain-Containing Protein 92 3     KIAA01223 5
GPATC92 3     ZRANB52
GPATCH92 3     RNA-Binding Protein 102
S1-12 3     RNA-Binding Motif Protein 103

External Ids:    HGNC: 98961   Entrez Gene: 82412   Ensembl: ENSG000001828727   OMIM: 3000805   UniProtKB: P981753   

Export aliases for RBM10 gene to outside databases

Previous GC identifers: GC0XP045807 GC0XP045265 GC0XP045830 GC0XP046050 GC0XP046760 GC0XP046889 GC0XP044717


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RBM10 Gene:
This gene encodes a nuclear protein that belongs to a family proteins that contain an RNA-binding motif. The
encoded protein associates with hnRNP proteins and may be involved in regulating alternative splicing. Defects in
this gene are the cause of the X-linked recessive disorder, TARP syndrome. Alternate splicing results in multiple
transcript variants.(provided by RefSeq, Mar 2011)

GeneCards Summary for RBM10 Gene: 
RBM10 (RNA binding motif protein 10) is a protein-coding gene. Diseases associated with RBM10 include tarp syndrome, and lymphogranuloma venereum. GO annotations related to this gene include RNA binding and nucleotide binding. An important paralog of this gene is RBM6.

UniProtKB/Swiss-Prot: RBM10_HUMAN, P98175
Function: May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA
homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity)

Gene Wiki entry for RBM10 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NT_079573.4  NC_018934.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RBM10 gene promoter:
         ER-alpha   C/EBPbeta   p53   MyoD   LUN-1   Nkx2-5   Arnt   PPAR-gamma1   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRBM10 promoter sequence
   Search SABiosciences Chromatin IP Primers for RBM10

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RBM10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp11.23   Ensembl cytogenetic band:  Xp11.23   HGNC cytogenetic band: Xp11.3

RBM10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RBM10 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP047004:  view genomic region     (about GC identifiers)

Start:
47,004,268 bp from pter      End:
47,046,214 bp from pter
Size:
41,947 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RBM10_HUMAN, P98175 (See protein sequence)
Recommended Name: RNA-binding protein 10  
Size: 930 amino acids; 103533 Da
Subunit: Associates with the spliceosome. Component of a large chromatin remodeling complex, at least composed of
MYSM1, PCAF, RBM10 and KIF11/TRIP5
Subcellular location: Nucleus. Note=In the extranucleolar nucleoplasm constitutes hundreds of nuclear domains,
which dynamically change their structures in a reversible manner. Upon globally reducing RNA polymerase II
transcription, the nuclear bodies enlarge and decrease in number. They occur closely adjacent to nuclear speckles
or IGCs (interchromatin granule clusters) but coincide with TIDRs (transcription-inactivation-dependent RNA
domains)
Sequence caution: Sequence=AAB33572.1; Type=Frameshift; Positions=696; Sequence=BAA09471.1; Type=Erroneous
initiation; Sequence=CAB70731.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=CAB70731.1; Type=Frameshift; Positions=Several;
2 PDB 3D structures from and Proteopedia for RBM10:
2LXI (3D)        2M2B (3D)    
Secondary accessions: C4AM81 Q14136 Q5JRR2 Q9BTE4 Q9BTX0 Q9NTB1
Alternative splicing: 4 isoforms:  P98175-1   P98175-2   P98175-3   P98175-4   

Explore the universe of human proteins at neXtProt for RBM10: NX_P98175

Explore proteomics data for RBM10 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P98175

  • RBM10 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RBM10 Protein Expression
    REFSEQ proteins (5 alternative transcripts): 
    NP_001191395.1  NP_001191396.1  NP_001191397.1  NP_005667.2  NP_690595.1  

    ENSEMBL proteins: 
     ENSP00000366829   ENSP00000329659   ENSP00000328848  

    Human Recombinant Protein Products for RBM10: 
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    Cloud-Clone Corp. Proteins for RBM10 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus NAS--
    GO:0005730NOT nucleolus IDA--

    RBM10 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    GPATCH: G patch domain containing
    RBM: RNA binding motif (RRM) containing
    ZRANB: Zinc fingers, RAN-binding domain containing

    5/6 InterPro protein domains (see all 6):
     IPR012677 Nucleotide-bd_a/b_plait
     IPR015880 Znf_C2H2-like
     IPR000467 G_patch_dom
     IPR001876 Znf_RanBP2
     IPR000504 RRM_dom

    Graphical View of Domain Structure for InterPro Entry P98175

    ProtoNet protein and cluster: P98175

    3 Blocks protein domains:
    IPB000467 D111/G-patch domain
    IPB000504 RNA-binding region RNP-1 (RNA recognition motif)
    IPB001876 Zn-finger


    UniProtKB/Swiss-Prot: RBM10_HUMAN, P98175
    Similarity: Contains 1 C2H2-type zinc finger
    Similarity: Contains 1 G-patch domain
    Similarity: Contains 1 RanBP2-type zinc finger
    Similarity: Contains 2 RRM (RNA recognition motif) domains


    RBM10 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RBM10_HUMAN, P98175
    Function: May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA
    homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity)

         Genatlas biochemistry entry for RBM10:
    RNA binding motif protein 10,expressed probe DXS8237-clone1,1,3kb,homolog to RBM5 located on chromosome 3,in a
    region duplicated from Xp11.3-p11.23

         Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding NAS--
    GO:0005515protein binding IPI--
    GO:0008270zinc ion binding IEA--
         
    RBM10 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for RBM10:
     Decreased POU5F1-GFP protein e 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Rbm10):
     normal 

    RBM10 for phenotypes           About GeneDecksing

    Animal Models:
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RBM10

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/756 Interacting proteins for RBM10 (P981752, 3 ENSP000003668294) via UniProtKB, MINT, STRING, and/or I2D (see all 756)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATN1P542592, 3, ENSP000003490764MINT-2864917 I2D: score=3 STRING: ENSP00000349076
    AGO3Q9H9G72, 3, ENSP000003622874MINT-6489217 I2D: score=1 STRING: ENSP00000362287
    SF3A2Q154282, 3, ENSP000002214944MINT-5206151 I2D: score=1 STRING: ENSP00000221494
    LMNAP025452, 3MINT-7945693 I2D: score=1 
    YWHAEP622582, 3MINT-8395092 I2D: score=1 
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IEA--
    GO:0006397mRNA processing IEA--
    GO:0008150biological_process ND--
    GO:0008285negative regulation of cell proliferation IEA--
    GO:0008380RNA splicing IEA--

    RBM10 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RBM10

    Search CenterWatch for drugs/clinical trials and news about RBM10

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RBM10 gene (5 alternative transcripts): 
    NM_001204466.1  NM_001204467.1  NM_001204468.1  NM_005676.4  NM_152856.2  

    Unigene Cluster for RBM10:

    RNA binding motif protein 10
    Hs.401509  [show with all ESTs]
    Unigene Representative Sequence: NM_001204468
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000377604(uc004dhe.2 uc004dhf.3 uc004dhi.3 uc004dhh.3 uc010nhq.3 uc004dhg.3)
    ENST00000468791 ENST00000345781 ENST00000496012 ENST00000478410 ENST00000329236

    miRNA
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    hsa-miR-224 hsa-miR-520d-5p hsa-miR-524-5p hsa-miR-556-3p
    SwitchGear 3'UTR luciferase reporter plasmidRBM10 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AK000962.1 AK024839.1 AK025854.1 AK225175.1 AK292758.1 AL137421.1 BC000681.2 BC003089.1 
    BC004181.2 BC008733.2 BC024153.2 BX537969.1 D50912.1 U35373.1 

    13 DOTS entries:

    DT.454683  DT.100889289  DT.101983909  DT.91763340  DT.100889319  DT.121643281  DT.95208020  DT.95208037 
    DT.121282101  DT.75150606  DT.91763346  DT.40116071  DT.95208046 

    24/357 AceView cDNA sequences (see all 357):

    CB160234 CA434490 BG059925 BQ941562 BQ882827 CB988764 BM663829 AA968949 
    AA194785 BG031128 BU682839 AW249225 BC000681 BQ944799 CR612855 CA439924 
    BC024153 BQ000779 BU849772 AL079775 CA454070 CB045546 BC004181 AL537676 

    GeneLoc Exon Structure

    5/12 Alternative Splicing Database (ASD) splice patterns (SP) for RBM10 (see all 12)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14a · 14b ^ 15 ^ 16 ^
    SP1:                                -     -                       -     -     -     -                                   -                                       
    SP2:                                                                                                                    -                                       
    SP3:                                                                                                                    -                                       
    SP4:                                                                                                                                                            
    SP5:                                                                                                                    -                                       

    ExUns: 17a · 17b ^ 18 ^ 19a · 19b ^ 20 ^ 21a · 21b ^ 22 ^ 23a · 23b ^ 24 ^ 25 ^ 26a · 26b ^ 27
    SP1:                                                                                                
    SP2:                                                                                                
    SP3:                                                                                                
    SP4:                                                                                                
    SP5:                                                                                                


    ECgene alternative splicing isoforms for RBM10

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RBM10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGGGTGTCC
    RBM10 Expression
    About this image


    See RBM10 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RBM10

    SOURCE GeneReport for Unigene cluster: Hs.401509
        SABiosciences Custom PCR Arrays for RBM10
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for RBM10 gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rbm101 , 5 RNA binding motif protein 101, 5 90.2(n)1
    96.23(a)1
      X (16.11 cM)5
    2367321  NM_145627.21  NP_663602.11 
     206175035 
    lizard
    (Anolis carolinensis)
    Reptilia RBM106
    RNA binding motif protein 10
    77(a)
    1 ↔ 1
    2(68925269-68955715)
    zebrafish
    (Danio rerio)
    Actinopterygii RBM106
    RNA binding motif protein 10
    56(a)
    1 ↔ 1
    23(906479-933614)
    fruit fly
    (Drosophila melanogaster)
    Insecta CG48963 RNA binding 29(a)   21F2   --
    worm
    (Caenorhabditis elegans)
    Secernentea T08B2.56
    Protein T08B2.5, isoform b
    22(a)
    1 → many
    I(6215669-6219911)


    ENSEMBL Gene Tree for RBM10 (if available)
    TreeFam Gene Tree for RBM10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RBM10 gene
    RBM62  RBM52  
    2 SIMAP similar genes for RBM10 using alignment to 2 protein entries:     RBM10_HUMAN (see all proteins):
    DKFZp686E2459    RBM5

    RBM10 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/571 SNPs in RBM10 are shown (see all 571)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0354864
    A colorectal cancer sample4--see VAR_0354862 R H mis40--------
    rs1425556301,2
    --46921820(+) TCTATA/GTTTAC 5 -- us2k10--------
    rs44924991,2
    C,F,A,H--46922026(+) ctggcG/Atacag 5 -- us2k119Minor allele frequency- A:0.47NS EA NA WA CSA 1971
    rs128357171,2
    C--46922099(+) GAGGTT/GAGTAT 5 -- us2k12Minor allele frequency- G:0.00NA 4
    rs128357261,2
    C--46922117(+) GTACTG/TATTAT 5 -- us2k10--------
    rs1479581471,2
    C--46922146(+) AGAAAC/TACCTC 5 -- us2k10--------
    rs1874862241,2
    --46922148(+) AAACAC/TCTCAC 5 -- us2k10--------
    rs1419081531,2
    C--46922216(+) ACTTAC/TGAAGT 5 -- us2k10--------
    rs1929483611,2
    --46922426(+) ACAGCA/GGACCT 5 -- us2k10--------
    rs1436513791,2
    --46922434(+) CCTGGC/TAGCCC 5 -- us2k10--------

    HapMap Linkage Disequilibrium report for RBM10 (47004268 - 47046214 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for RBM10:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2740136CNV Deletion23290073
    esv2740135CNV Deletion23290073
    nsv6886CNV Loss18451855


    Human Gene Mutation Database (HGMD): RBM10

    Locus Specific Mutation Databases (LSDB): RBM10
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing RBM10
    DNA2.0 Custom Variant and Variant Library Synthesis for RBM10

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 300080   
    OMIM disorders: 311900  
    UniProtKB/Swiss-Prot: RBM10_HUMAN, P98175
  • TARP syndrome (TARPS) [MIM:311900]: A disorder characterized by the Robin sequence (micrognathia,
    glossoptosis and cleft palate), talipes equinovarus and cardiac defects. Note=The disease is caused by mutations
    affecting the gene represented in this entry

  • 5 diseases for RBM10:    About MalaCards
    tarp syndrome    lymphogranuloma venereum    talipes equinovarus    cleft palate
    breast cancer

    1 disease from the University of Copenhagen DISEASES database for RBM10:
    Lymphogranuloma venereum

    RBM10 for disorders           About GeneDecksing


    Export disorders for RBM10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RBM10 gene, integrated from 9 sources (see all 59):
    (articles sorted by number of sources associating them with RBM10)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel gene, DXS8237E, lies within 20 kb upstream of UBE1 in Xp11.23 and has a different X inactivation status. (PubMed id 8808293)1, 2, 3, 9 Coleman M.P....Davies K.E. (1996)
    2. Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 8590280)1, 2, 3 Nagase T....Nomura N. (1995)
    3. Massively parallel sequencing of exons on the X chrom osome identifies RBM10 as the gene that causes a syndromic form of cleft palate . (PubMed id 20451169)1, 2 Johnston J.J.... L.G. (2010)
    4. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)1, 2 Dephoure N.... Gygi S.P. (2008)
    5. S1-1 nuclear domains: characterization and dynamics as a function of transcriptional activity. (PubMed id 18315527)1, 2 Inoue A.... Tani T. (2008)
    6. A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation. (PubMed id 17707232)1, 2 Zhu P....Rosenfeld M.G. (2007)
    7. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    9. An integrated, functionally annotated gene map of the DXS8026-ELK1 interval on human Xp11.3-Xp11.23: potential hotspot for neurogenetic disorders. (PubMed id 11944989)1, 9 Thiselton D.L.... Meindl A. (2002)
    10. Deubiquitinase FAM/USP9X interacts with the E3 ubiquit in ligase SMURF1 protein and protects it from ligase activity-dependent self-deg radation. (PubMed id 23184937)1 Xie Y....Cong F. (2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8241 HGNC: 9896 AceView: RBM10 Ensembl:ENSG00000182872 euGenes: HUgn8241
    ECgene: RBM10 H-InvDB: RBM10

    (According to HUGE)
    About This Section
    HUGE: KIAA0122

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RBM10 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RBM10 gene:
    Search GeneIP for patents involving RBM10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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