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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

RBKS Gene

protein-coding GIFtS: 57
GCID: GC02M028004

ribokinase

Explore 2 diseases affiliated with
RBKS via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Ribokinase¹
RBSK¹ ² ³
DKFZp686G13268¹
5230400M11Rik²
EC 2.7.1.15³

External Ids:	HGNC: 30325¹	Entrez Gene: 64080²	Ensembl: ENSG00000171174⁷	OMIM: 611132⁵	UniProtKB: Q9H477³

Export aliases for RBKS gene to outside databases

Previous GC identifers: GC02M027978 GC02M027915 GC02M027857 GC02M027745

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RBKS:

The ribokinase encoded by this gene belongs to the pfkB family of carbohydrate kinases. It phosphorylates ribose to

form ribose-5-phosphate in the presence of ATP and magnesium as a first step in ribose metabolism. (provided by

RefSeq, Jul 2008)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000002.11 NC_018913.1 NT_022184.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the RBKS gene promoter:
CREB deltaCREB
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): RBKS promoter sequence

Search SABiosciences Chromatin IP Primers for RBKS

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RBKS

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p23.3 Ensembl cytogenetic band: 2p23.2 HGNC cytogenetic band: 2p23.3

RBKS Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RBKS gene location

GeneLoc information about chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02M028004: view genomic region (about GC identifiers)

Start:	28,004,231 bp from pter	End:	28,113,965 bp from pter
Size:	109,735 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RBSK_HUMAN, Q9H477 (See protein sequence)

Recommended Name: Ribokinase

Size: 322 amino acids; 34143 Da

1 PDB 3D structure from and Proteopedia for RBKS:

2FV7 (3D)

Secondary accessions: A9UK04

Explore the universe of human proteins at neXtProt for RBKS: NX_Q9H477

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9H477

RBKS Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_071411.1

ENSEMBL proteins:

ENSP00000306817 ENSP00000413789 ENSP00000393558 ENSP00000415975 ENSP00000413232

Human Recombinant Protein Products for RBKS:

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	Uscn ELISAs and CLIAs for RBKS

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

RBKS for domains About GeneDecksing

4 InterPro domains/families:

IPR011611 PfkB_dom

IPR011877 D_ribokin_bac

IPR002139 Ribokinase

IPR002173 Carboh/pur_kinase_PfkB_CS

Graphical View of Domain Structure for InterPro Entry Q9H477

ProtoNet protein and cluster: Q9H477

2 Blocks protein families:

IPB002139 Ribokinase signature

IPB002173 Carbohydrate kinase

UniProtKB/Swiss-Prot: RBSK_HUMAN, Q9H477

Similarity: Belongs to the carbohydrate kinase PfkB family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: RBSK_HUMAN, Q9H477

Catalytic activity: ATP + D-ribose = ADP + D-ribose 5-phosphate

Enzyme regulation: Competitively inhibited by phosphonoacetic acid, etidronate, 2-carboxethylphosphonic acid,

N-(phosphonomethyl)glycine, N-(phosphonomethyl)iminodiacetic acid and clodronate

Enzyme Number (IUBMB): EC 2.7.1.15¹

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004747	ribokinase activity	IEA	--
GO:0005524	ATP binding	IEA	--

RBKS for ontologies About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for RBKS

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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RBKS
		1 QIAGEN miScript miRNA Assays for microRNA that regulate RBKS:
		hsa-miR-518a-5p
		SwitchGear 3'UTR luciferase reporter plasmid: RBKS 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RBKS (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RBKS OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBKS

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Pentose phosphate pathway

Pentose phosphate pathway

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

1 Kegg Pathway (Kegg details for RBKS):

Pentose phosphate pathway

UniProtKB/Swiss-Prot: RBSK_HUMAN, Q9H477

Pathway: Carbohydrate metabolism; D-ribose degradation; D-ribose 5-phosphate from beta-D-ribopyranose: step 2/2

RBKS for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for RBKS

STRING Interaction Network Preview (showing 5 interactants - click image to see 15)

5/45 Interacting proteins for RBKS (Q9H477³ ENSP00000306817⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 45)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ADI1	Q9BV57³, ENSP00000333666⁴	I2D: score=1 STRING: ENSP00000333666
SRR	Q9GZT4³, ENSP00000339435⁴	I2D: score=1 STRING: ENSP00000339435
CAT	P04040³, ENSP00000241052⁴	I2D: score=1 STRING: ENSP00000241052
ABAT	P80404³	I2D: score=1
ACO2	Q99798³	I2D: score=1

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006014	D-ribose metabolic process	--	--
GO:0019303	D-ribose catabolic process	IEA	--

RBKS for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

RBKS for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for RBKS

8 HMDB Compounds for RBKS About this table

Compound	Synonyms	CAS #	PubMed Ids
ADP	adenosindiphosphorsaeure (see all 8)	58-64-0	--
Adenosine triphosphate	5'-(tetrahydrogen triphosphate) Adenosine (see all 24)	56-65-5	--
D-Ribose	d-Ribose (see all 11)	50-69-1	--
D-Ribose 5-phosphate	D-Ribose 5-phosphate (see all 11)	3615-55-2	--
D-Ribulose 5-phosphate	D-Ribulose 5-phosphate (see all 5)	4151-19-3	--
Deoxyribose	2'-Deoxy-D-ribose	533-67-5	--
Deoxyribose 1-phosphate	2-deoxy-D-ribose-1-phosphate (see all 14)	17210-42-3	--
Deoxyribose 5-phosphate	2-deoxy-alpha-D-ribose 5-phosphate (see all 12)	102916-66-5	--

4 Novoseek chemical compound relationships for RBKS gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
ribose	75.3	3	9843365 (1), 11563694 (1), 18560757 (1)
pyridoxal	69.4	4	12235162 (3), 16600635 (1)
vitamin b6	50.4	1	16600635 (1)
atp	48.8	1	9843365 (1)

Search CenterWatch for drugs/clinical trials and news about RBKS / RBSK

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for RBKS gene:

NM_022128.1

Unigene Cluster for RBKS:

Ribokinase

Hs.11916 [show with all ESTs]

Unigene Representative Sequence: BX648909

5 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000302188(uc002rlo.1) ENST00000449378(uc010ezi.1) ENST00000458185

ENST00000453412 ENST00000444339(uc010ymg.2)

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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RBKS
		1 QIAGEN miScript miRNA Assays for microRNA that regulate RBKS:
		hsa-miR-518a-5p
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Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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		Sirion Biotech Custom design and validation of potent shRNA sequences against RBKS

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		GenScript: all cDNA clones in your preferred vector: RBKS (NM_022128)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for RBKS
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RBKS
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RBKS

Additional cDNA sequence:

AJ404857.1 AK300989.1 AY643715.1 BC017425.1 BX648909.1

7 DOTS entries:

DT.86841549 DT.99952795 DT.100772021 DT.101956972 DT.65287474 DT.100772013 DT.121024220

24/90 AceView cDNA sequences (see all 90):

AI452781 CR609030 CD671167 BQ016020 BC014088 BE218181 CA434266 AI912209

H82519 AA860865 AJ404857 BE221723 BE501861 BM717190 NM_022128 BG697021

BG201690 BM714050 BU621759 AI203169 AV657234 CD671166 AA393609 CD515982

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for RBKS About this scheme

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9
SP1:					-
SP2:

ECgene alternative splicing isoforms for RBKS

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

RBKS expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTCAACAGAT

About this image

RBKS expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Posterior foregut-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See RBKS Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RBKS

SOURCE GeneReport for Unigene cluster: Hs.11916

SABiosciences Expression via Pathway-Focused PCR Array including RBKS:

Glucose Metabolism in human mouse rat

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBKS

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the last universal common ancestor (LUCA).

Orthologs for RBKS gene from 10/33 species (see all 33) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Rbks^{1 , 5}	ribokinase^{1, 5}	85.82(n)¹ 86.34(a)¹		5 (17.27 cM)⁵ 71336¹ NM_153196.1¹ NP_694876.1¹ 31624439⁵
chicken (Gallus gallus)	Aves	RBKS¹	ribokinase	74.72(n) 72.82(a)		421418 XM_419471.3 XP_419471.3
lizard (Anolis carolinensis)	Reptilia	RBKS⁶	--	75(a)	1 ↔ 1	2(125468000-125518682)
zebrafish (Danio rerio)	Actinopterygii	rbks¹	ribokinase	65.47(n) 67.32(a)		415207 NM_001002117.1 NP_001002117.1
fruit fly (Drosophila melanogaster)	Insecta	CG13369¹	CG13369	50.74(n) 46.08(a)		31007 NM_130494.3 NP_569850.1
worm (Caenorhabditis elegans)	Secernentea	F07A11.5¹	Protein F07A11.5	51.03(n) 45.52(a)		174781 NM_064082.3 NP_496483.1
baker's yeast (Saccharomyces cerevisiae)	Saccharomycetes	RBK1(YCR036W)⁴ RBK1¹	Putative ribokinase⁴ Rbk1p¹	44.22(n)¹ 32.65(a)¹		3(193297-194298)⁴ 850402^{1, 4} NP_009965.2^{1, 4}
thale cress (Arabidopsis thaliana)	eudicotyledons	AT1G17160¹	ribokinase	41.51(n) 29.35(a)		838287 NM_101577.4 NP_173159.1
rice (Oryza sativa)	Liliopsida	Os01g0665400¹	hypothetical protein	40.59(n) 30.95(a)		4326855 NM_001050331.1 NP_001043796.1
E. coli (Escherichia coli)	Gamma proteobacteria	rbsK⁶ yihV⁶ (see all 3)	predicted sugar kinase (see all 3)	34(a) 27(a) (see all 3)	1 ↔ 1 possible ortholog (see all 3)	Chromosome(3935317-3936246) Chromosome(4071762-4072658)

ENSEMBL Gene Tree for RBKS (if available)
TreeFam Gene Tree for RBKS (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 2 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs35216618^1,2	C	--	27793030(+)	`CAGTG-/TTTTTT`	1	--	int¹		1		NA	2
rs7566679^1,2	C	--	28003811(+)	`gttatC/Gctccc`	1	--	ds500¹		0	--	--	--	--
rs117080140^1,2	C	--	28004114(+)	`CAGCTG/CCCCCT`	1	--	ds500¹		1		EA	120
rs114212707^1,2	C,F	--	28004197(+)	`CCATAT/GGGTGC`	1	--	ds500¹		1		WA	118
rs140736514^1,2		--	28004286(+)	`AATTCC/TGGTTG`	1	--	ut3¹		0	--	--	--	--
rs115020191^1,2		--	28004329(+)	`ATCGTT/CATAAA`	1	--	ut3¹		1		WA	118
rs187524087^1,2		--	28004364(+)	`CGTAAA/CAGAAC`	1	--	ut3¹		0	--	--	--	--
rs190128259^1,2		--	28004424(+)	`CAGGAA/GCAGCC`	1	--	ut3¹		0	--	--	--	--
rs182727100^1,2	C	--	28004465(+)	`TTTATA/TTTGGG`	1	--	ut3¹		0	--	--	--	--
rs150425990^1,2	C,F	--	28004583(+)	`GAGCAT/CGTCTT`	2	/M /V	mis¹		1		NA	4550

HapMap Linkage Disequilibrium report for RBKS (28004231 - 28113965 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for RBKS
1 CNV: 3347

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RBKS

DNA2.0 Custom Variant and Variant Library Synthesis for RBKS

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

RBKS for disorders           About GeneDecksing

OMIM gene information: 611132    OMIM disorders: --

2 diseases for RBKS:    About MalaCards

tuberculosis mycobacterium tuberculosis

Human Genome Epidemiology (HuGE) Navigator: RBKS (1 document)

Export disorders for RBKS gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for RBKS gene, integrated from 9 sources (see all 21):
(articles sorted by number of sources associating them with RBKS)

Utopia: connect your pdf to the dynamic
world of online information

Identification and characterization of human ribokinase and comparison of its properties with E. coli ribokinase and human adenosine kinase. (PubMed id 17585908)^{1, 2, 9} Park J.... Gupta R.S. (2007)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Convergent evolution of similar enzymatic function on different protein folds: the hexokinase, ribokinase, and galactokinase families of sugar kinases. (PubMed id 8382990)^{1, 3} Bork P....Valencia A. (1993)
Genome-wide YFP fluorescence complementation screen id entifies new regulators for telomere signaling in human cells. (PubMed id 21044950)¹ Lee O.H....Songyang Z. (2011)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )² Aoki H.... Hino O. (2000)
Crystal structure of an aminoimidazole riboside kinase from Salmonella enterica: implications for the evolution of the ribokinase superfamily. (PubMed id 15458630)⁹ Zhang Y....Ealick S.E. (2004)
The effect of inorganic phosphate on the activity of bacterial ribokinase. (PubMed id 11563694)⁹ Maj M.C. and Gupta R.S. (2001)
Crystal structure of brain pyridoxal kinase, a novel member of the ribokinase superfamily. (PubMed id 12235162)⁹ Li M.H....Liang D.C. (2002)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 64080	HGNC: 30325	AceView: RBKS	Ensembl:ENSG00000171174	euGenes: HUgn64080
ECgene: RBKS	Kegg: 64080	H-InvDB: RBKS

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for RBKS	Pharmacogenomics, SNPs, Pathways

Intellectual Property for RBKS gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for RBKS gene:
Search GeneIP for patents involving RBKS

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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RBKS Gene

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