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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RBKS Gene

protein-coding   GIFtS: 58
GCID: GC02M028004

Ribokinase

Microbiology & Infectious Diseases Congress
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
ribokinase1 2
RBSK2 3
5230400M11Rik2
EC 2.7.1.153

External Ids:    HGNC: 303251   Entrez Gene: 640802   Ensembl: ENSG000001711747   OMIM: 6111325   UniProtKB: Q9H4773   

Export aliases for RBKS gene to outside databases

Previous GC identifers: GC02M027978 GC02M027915 GC02M027857 GC02M027745


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RBKS Gene:
The ribokinase encoded by this gene belongs to the pfkB family of carbohydrate kinases. It phosphorylates ribose
to form ribose-5-phosphate in the presence of ATP and magnesium as a first step in ribose metabolism. (provided
by RefSeq, Jul 2008)

GeneCards Summary for RBKS Gene: 
RBKS (ribokinase) is a protein-coding gene. Diseases associated with RBKS include tuberculosis. GO annotations related to this gene include ribokinase activity and ATP binding.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.2  NT_022184.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RBKS gene promoter:
         CREB   deltaCREB   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): RBKS promoter sequence
   Search SABiosciences Chromatin IP Primers for RBKS

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RBKS


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p23.3   Ensembl cytogenetic band:  2p23.2   HGNC cytogenetic band: 2p23.3

RBKS Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RBKS gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M028004:  view genomic region     (about GC identifiers)

Start:
28,004,231 bp from pter      End:
28,113,965 bp from pter
Size:
109,735 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RBSK_HUMAN, Q9H477 (See protein sequence)
Recommended Name: Ribokinase  
Size: 322 amino acids; 34143 Da
1 PDB 3D structure from and Proteopedia for RBKS:
2FV7 (3D)    
Secondary accessions: A9UK04

Explore the universe of human proteins at neXtProt for RBKS: NX_Q9H477

Explore proteomics data for RBKS at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9H477

  • RBKS Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RBKS Protein Expression
    REFSEQ proteins: NP_071411.1  
    ENSEMBL proteins: 
     ENSP00000306817   ENSP00000413789   ENSP00000393558   ENSP00000415975   ENSP00000413232  

    Human Recombinant Protein Products for RBKS: 
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    Novus Biologicals RBKS Proteins
    Novus Biologicals RBKS Lysates
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    Cloud-Clone Corp. Proteins for RBKS 


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    Cloud-Clone Corp. ELISAs for RBKS 
    Cloud-Clone Corp. CLIAs for RBKS


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR011611 PfkB_dom
     IPR011877 D_ribokin_bac
     IPR002139 Ribokinase
     IPR002173 Carboh/pur_kinase_PfkB_CS

    Graphical View of Domain Structure for InterPro Entry Q9H477

    ProtoNet protein and cluster: Q9H477

    2 Blocks protein domains:
    IPB002139 Ribokinase signature
    IPB002173 Carbohydrate kinase


    UniProtKB/Swiss-Prot: RBSK_HUMAN, Q9H477
    Similarity: Belongs to the carbohydrate kinase PfkB family


    RBKS for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RBSK_HUMAN, Q9H477
    Catalytic activity: ATP + D-ribose = ADP + D-ribose 5-phosphate
    Enzyme regulation: Competitively inhibited by phosphonoacetic acid, etidronate, 2-carboxethylphosphonic acid,
    N-(phosphonomethyl)glycine, N-(phosphonomethyl)iminodiacetic acid and clodronate

         Enzyme Number (IUBMB): EC 2.7.1.151

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004747ribokinase activity IEA--
    GO:0005524ATP binding IEA--
         
    RBKS for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for RBKS 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for RBKS

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RBKS 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RBKS 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RBKS
    1 QIAGEN miScript miRNA Assays for microRNA that regulate RBKS:
    hsa-miR-518a-5p
    SwitchGear 3'UTR luciferase reporter plasmidRBKS 3' UTR sequence
    Inhib. RNA
    Products:
        
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for RBKS About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Pentose phosphate pathway
    Pentose phosphate pathway

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways




    1         Kegg Pathway  (Kegg details for RBKS):
        Pentose phosphate pathway

    UniProtKB/Swiss-Prot: RBSK_HUMAN, Q9H477
    Pathway: Carbohydrate metabolism; D-ribose degradation; D-ribose 5-phosphate from beta-D-ribopyranose: step 2/2


    RBKS for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RBKS

    STRING Interaction Network Preview (showing 5 interactants - click image to see 15)

    5/45 Interacting proteins for RBKS (Q9H4773 ENSP000003068174) via UniProtKB, MINT, STRING, and/or I2D (see all 45)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    ADI1Q9BV573, ENSP000003336664I2D: score=1 STRING: ENSP00000333666
    SRRQ9GZT43, ENSP000003394354I2D: score=1 STRING: ENSP00000339435
    CATP040403, ENSP000002410524I2D: score=1 STRING: ENSP00000241052
    ABATP804043I2D: score=1 
    ACO2Q997983I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006014D-ribose metabolic process ----
    GO:0019303D-ribose catabolic process IEA--

    RBKS for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    RBKS for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RBKS (RBSK)

    8 HMDB Compounds for RBKS    About this table
    CompoundSynonyms CAS #PubMed Ids
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    D-Ribosed-Ribose (see all 11)50-69-1--
    D-Ribose 5-phosphateD-Ribose 5-phosphate (see all 11)3615-55-2--
    D-Ribulose 5-phosphateD-Ribulose 5-phosphate (see all 5)4151-19-3--
    Deoxyribose2'-Deoxy-D-ribose 533-67-5--
    Deoxyribose 1-phosphate2-deoxy-D-ribose-1-phosphate (see all 14)17210-42-3--
    Deoxyribose 5-phosphate2-deoxy-alpha-D-ribose 5-phosphate (see all 12)102916-66-5--

    4 Novoseek inferred chemical compound relationships for RBKS gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    ribose 75.3 3 9843365 (1), 11563694 (1), 18560757 (1)
    pyridoxal 69.4 4 12235162 (3), 16600635 (1)
    vitamin b6 50.4 1 16600635 (1)
    atp 48.8 1 9843365 (1)

    Search CenterWatch for drugs/clinical trials and news about RBKS / RBSK

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RBKS gene: 
    NM_022128.1  

    Unigene Cluster for RBKS:

    Ribokinase
    Hs.11916  [show with all ESTs]
    Unigene Representative Sequence: BX648909
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000302188(uc002rlo.1) ENST00000449378(uc010ezi.1) ENST00000458185
    ENST00000453412 ENST00000444339(uc010ymg.2)
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RBKS
    1 QIAGEN miScript miRNA Assays for microRNA that regulate RBKS:
    hsa-miR-518a-5p
    SwitchGear 3'UTR luciferase reporter plasmidRBKS 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for RBKS
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RBKS
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    OriGene clones in human, mouse for RBKS (see all 6)
    OriGene ORF clones in mouse, rat for RBKS
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RBKS (NM_022128)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RBKS
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RBKS
    Sirion Biotech Customized lentivirus for stable overexpression of RBKS 
                         Customized lentivirus expression plasmids for stable overexpression of RBKS 
    Primer
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    OriGene qPCR primer pairs and template standards for RBKS
    OriGene qSTAR qPCR primer pairs in human, mouse for RBKS
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RBKS
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RBKS
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RBKS

    Additional mRNA sequence: 

    AJ404857.1 AK300989.1 AY643715.1 BC017425.1 BX648909.1 

    7 DOTS entries:

    DT.86841549  DT.99952795  DT.100772021  DT.101956972  DT.65287474  DT.100772013  DT.121024220 

    24/90 AceView cDNA sequences (see all 90):

    AJ404857 BE221723 AI912209 CD671167 BE501861 BE218181 BM717190 CA434266 
    BQ016020 AI452781 BC014088 CR609030 AA860865 H82519 NM_022128 AI343945 
    AA348964 CD671166 CD515982 BM833322 AI203169 BU621759 BX648909 AI266440 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for RBKS    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9
    SP1:              -                                             
    SP2:                                                            


    ECgene alternative splicing isoforms for RBKS

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RBKS expression in normal human tissues (normalized intensities)      RBKS embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTCAACAGAT
    RBKS Expression
    About this image


    RBKS expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/6 selected tissues (see all 6) fully expand
     
     Epithelium (Respiratory System)    fully expand to see all 3 entries
             bronchial epithelia   
     
     Intestine (Gastrointestinal Tract)
             small intestine   
     
     Pancreas (Endocrine System)
             Posterior foregut-like cells ( A scalable, suspension protocol for derivation of...
     
     Endothelium (Cardiovascular System)
             blood vessel   
     
     Adrenal Gland (Endocrine System)
             adrenal cortex   

    See RBKS Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RBKS

    SOURCE GeneReport for Unigene cluster: Hs.11916
        SABiosciences Expression via Pathway-Focused PCR Array including RBKS: 
              Glucose Metabolism in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBKS

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RBKS gene from 9/20 species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rbks1 , 5 ribokinase1, 5 85.82(n)1
    86.34(a)1
      5 (17.27 cM)5
    713361  NM_153196.11  NP_694876.11 
     316244395 
    chicken
    (Gallus gallus)
    Aves RBKS1 ribokinase 74.72(n)
    72.82(a)
      421418  XM_419471.3  XP_419471.3 
    lizard
    (Anolis carolinensis)
    Reptilia RBKS6
    Uncharacterized protein
    75(a)
    1 ↔ 1
    2(125468000-125541963)
    zebrafish
    (Danio rerio)
    Actinopterygii rbks1 ribokinase 65.47(n)
    67.32(a)
      415207  NM_001002117.1  NP_001002117.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG133691 CG13369 50.74(n)
    46.08(a)
      31007  NM_130494.3  NP_569850.1 
    worm
    (Caenorhabditis elegans)
    Secernentea F07A11.51 Protein F07A11.5 51.03(n)
    45.52(a)
      174781  NM_064082.3  NP_496483.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RBK1(YCR036W)4
    RBK11
    Putative ribokinase4
    Rbk1p1
    44.22(n)1
    32.65(a)1
      3(193297-194298)4
    8504021, 4  NP_009965.21, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G171601 ribokinase 41.51(n)
    29.35(a)
      838287  NM_101577.4  NP_173159.1 
    rice
    (Oryza sativa)
    Liliopsida Os01g06654001 hypothetical protein 40.59(n)
    30.95(a)
      4326855  NM_001050331.1  NP_001043796.1 


    ENSEMBL Gene Tree for RBKS (if available)
    TreeFam Gene Tree for RBKS (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RBKS gene
    1 SIMAP similar gene for RBKS using alignment to 5 protein entries:     RBSK_HUMAN (see all proteins):
    RBSK

    RBKS for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1739 SNPs in RBKS are shown (see all 1739)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs75666791,2
    C--28003811(+) gttatC/Gctccc 1 -- ds50010--------
    rs1170801401,2
    C,F--28004114(+) CAGCTG/CCCCCT 1 -- ds50011Minor allele frequency- C:0.01EA 120
    rs1142127071,2
    C,F--28004197(+) CCATAT/GGGTGC 1 -- ds50011Minor allele frequency- G:0.08WA 118
    rs1407365141,2
    C--28004286(+) AATTCC/TGGTTG 1 -- ut310--------
    rs1150201911,2
    C,F--28004329(+) ATCGTT/CATAAA 1 -- ut311Minor allele frequency- C:0.01WA 118
    rs1875240871,2
    --28004364(+) CGTAAA/CAGAAC 1 -- ut310--------
    rs1901282591,2
    --28004424(+) CAGGAA/GCAGCC 1 -- ut310--------
    rs1827271001,2
    C--28004465(+) TTTATA/TTTGGG 1 -- ut310--------
    rs2003108411,2
    C--28004570(+) AATTGA/C/GATCTG 3 S C F mis10--------
    rs1504259901,2
    C,F--28004583(+) GAGCAT/CGTCTT 2 /M /V mis11Minor allele frequency- C:0.00NA 4550

    HapMap Linkage Disequilibrium report for RBKS (28004231 - 28113965 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for RBKS:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2675195CNV Deletion23128226
    nsv507004CNV Insertion20534489
    esv274540CNV Insertion20981092
    esv268461CNV Insertion20981092
    nsv873758CNV Loss21882294
    nsv873759CNV Loss21882294
    nsv873760CNV Loss21882294
    dgv1162e1CNV Complex17122850

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611132    OMIM disorders: --

    2 diseases for RBKS:    About MalaCards
    tuberculosis    


    RBKS for disorders           About GeneDecksing

    Genetic Association Database (GAD): RBKS
    Human Genome Epidemiology (HuGE) Navigator: RBKS (1 document)

    Export disorders for RBKS gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RBKS gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with RBKS)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of human ribokinase and comparison of its properties with E. coli ribokinase and human adenosine kinase. (PubMed id 17585908)1, 2, 9 Park J.... Gupta R.S. (2007)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Convergent evolution of similar enzymatic function on different protein folds: the hexokinase, ribokinase, and galactokinase families of sugar kinases. (PubMed id 8382990)1, 3 Bork P....Valencia A. (1993)
    5. Genome-wide YFP fluorescence complementation screen id entifies new regulators for telomere signaling in human cells. (PubMed id 21044950)1 Lee O.H....Songyang Z. (2011)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    7. Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
    8. Crystal structure of an aminoimidazole riboside kinase from Salmonella enterica: implications for the evolution of the ribokinase superfamily. (PubMed id 15458630)9 Zhang Y....Ealick S.E. (2004)
    9. The effect of inorganic phosphate on the activity of bacterial ribokinase. (PubMed id 11563694)9 Maj M.C. and Gupta R.S. (2001)
    10. Crystal structure of brain pyridoxal kinase, a novel member of the ribokinase superfamily. (PubMed id 12235162)9 Li M.H....Liang D.C. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Aliases
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 64080 HGNC: 30325 AceView: RBKS Ensembl:ENSG00000171174 euGenes: HUgn64080
    ECgene: RBKS Kegg: 64080 H-InvDB: RBKS

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RBKS Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RBKS gene:
    Search GeneIP for patents involving RBKS

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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