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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RBFOX2 Gene

protein-coding   GIFtS: 48
GCID: GC22M036136

RNA binding protein, fox-1 homolog (C. elegans) 2

(Previous name: RNA binding motif protein 9 )
(Previous symbol: RBM9)
 Explore 8 diseases affiliated with
RBFOX2 via
MalaCards
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 Human Malady Compendium 
Biological research products
for RBFOX2    

Aliases
for RBFOX2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
RNA Binding Protein, Fox-1 Homolog (C. Elegans) 21 2     RNA-Binding Motif Protein 92 3
RBM91 2 3 5     FOX-21
HRNBP21 2 3     RNA Binding Motif Protein 91
FOX22 3 5     Fox-22
RTA2 3 5     DJ106I20.31
HNRBP21 2     Fox-1 Homologue2
Fox-1 Homolog B2 3     Fxh1
Hexaribonucleotide-Binding Protein 22 3     RNA Binding Protein Fox-1 Homolog 22
Repressor Of Tamoxifen Transcriptional Activity2 3     RNA-Binding Protein 93

External Ids:    HGNC: 99061   Entrez Gene: 235432   Ensembl: ENSG000001003207   OMIM: 6121495   UniProtKB: O432513   

Export aliases for RBFOX2 gene to outside databases

Previous GC identifer: GC22M019102


Summaries
for RBFOX2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for RBFOX2:
This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein
that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The
protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes
inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1
transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding
different isoforms have been found for this gene. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: RFOX2_HUMAN, O43251
Function: RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents
binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially
spliced exons during erythropoiesis (By similarity). RNA-binding protein that seems to act as a coregulatory factor of
ER-alpha

Gene Wiki entry for RBFOX2 (RBM9)


Genomic Views
for RBFOX2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000022.10  NC_018933.1  NT_011520.12  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for RBFOX2
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): RBFOX2 promoter sequence
   Search SABiosciences Chromatin IP Primers for RBFOX2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RBFOX2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.1   Ensembl cytogenetic band:  22q12.3   HGNC cytogenetic band: 22q12-q13

RBFOX2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RBFOX2 gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22M036136:  view genomic region     (about GC identifiers)

Start:
 36,134,783 bp from pter      End:
 36,424,585 bp from pter
Size:
 289,803 bases      Orientation:
 minus strand

Proteins
for RBFOX2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: RFOX2_HUMAN, O43251 (See protein sequence)
Recommended Name: RNA binding protein fox-1 homolog 2  
Size: 390 amino acids; 41374 Da
Subunit: Interacts with ER-alpha N-terminal activation domain
Subcellular location: Nucleus. Cytoplasm (By similarity)
1 PDB 3D structure from and Proteopedia for RBFOX2:
2CQ3 (3D)    
Secondary accessions: A4F5G8 A8K5Z5 B0QYY8 B0QYY9 Q0PRL5 Q0VH35 Q5TF71 Q6IC09 Q8TD00 Q8WYB1 Q96DZ6
Q96NL7 Q9UGW4 Q9UH33
Alternative splicing: 10 isoforms:  O43251-1   O43251-2   O43251-3   O43251-4   O43251-5   O43251-6   O43251-7   O43251-8   
O43251-9   O43251-10   (Ref.4 (BAB70875) sequence is in conflict in position: 8:H->Q)

Explore the universe of human proteins at neXtProt for RBFOX2: NX_O43251

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O43251

    • RBFOX2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (6 alternative transcripts): 
    NP_001026865.1  NP_001076045.1  NP_001076046.1  NP_001076047.1  NP_001076048.1  NP_055124.1  

    ENSEMBL proteins: 
     ENSP00000384944   ENSP00000407855   ENSP00000391670   ENSP00000262829   ENSP00000380470  
     ENSP00000352328   ENSP00000405651   ENSP00000413035   ENSP00000386177   ENSP00000380472  

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    Uscn Proteins for RBFOX2

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--


    RBFOX2 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for RBFOX2

    Protein Domains /
    Families
    for RBFOX2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    RBFOX2 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR012677 Nucleotide-bd_a/b_plait
     IPR025670 Fox-1_C_dom
     IPR017325 RNA-bd_Fox-1
     IPR000504 RRM_dom

    Graphical View of Domain Structure for InterPro Entry O43251

    ProtoNet protein and cluster: O43251

    1 Blocks protein family: IPB000504 RNA-binding region RNP-1 (RNA recognition motif)

    UniProtKB/Swiss-Prot: RFOX2_HUMAN, O43251
    Similarity: Contains 1 RRM (RNA recognition motif) domain


    Function
    for RBFOX2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: RFOX2_HUMAN, O43251
    Function: RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents
    binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially
    spliced exons during erythropoiesis (By similarity). RNA-binding protein that seems to act as a coregulatory factor of
    ER-alpha

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    hsa-miR-520f hsa-miR-3916 hsa-miR-877* hsa-miR-1273d hsa-miR-637 hsa-miR-508-5p hsa-miR-200b hsa-miR-4326
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0003676nucleic acid binding ----
    GO:0003714transcription corepressor activity IDA11875103
    GO:0003723RNA binding IDA11875103
    GO:0005515protein binding IPI16713569


    RBFOX2 for ontologies           About GeneDecksing


    3 GenomeRNAi human phenotypes for RBFOX2:
     Decreased homologous recombina  G0/1 arrest  Increased G1 DNA content 

    Animal Models:
         5 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Rbfox2):
     behavior/neurological  cellular  growth/size  mortality/aging  nervous system 

    RBFOX2 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for RBFOX2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RBFOX2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/52 Interacting proteins for RBFOX2 (O432511, 2, 3 ENSP000004130354) via UniProtKB, MINT, STRING, and/or I2D (see all 52)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATXN1P542531, 2, 3, ENSP000002447694EBI-746056,EBI-930964 MINT-2871171 MINT-2871190 MINT-2871209 MINT-2871228 MINT-2871247 MINT-2855267 I2D: score=3 STRING: ENSP00000244769
    RBFOX1Q9NWB11, 2, 3, ENSP000003091174EBI-746056,EBI-1047634 MINT-2855841 MINT-2871133 I2D: score=3 STRING: ENSP00000309117
    RBPMSQ930622, 3, ENSP000003401764MINT-67895 I2D: score=5 STRING: ENSP00000340176
    RHOXF2Q9BQY42, 3, ENSP000003604414MINT-66778 I2D: score=5 STRING: ENSP00000360441
    DMRTB1Q96MA12, 3, ENSP000003605004MINT-67864 I2D: score=4 STRING: ENSP00000360500
    About this table

    Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000381regulation of alternative mRNA splicing, via spliceosome ISS--
    GO:0006397mRNA processing IEA--
    GO:0008380RNA splicing IEA--
    GO:0010724regulation of definitive erythrocyte differentiation IEA--
    GO:0016070RNA metabolic process TAS11875103


    RBFOX2 for ontologies           About GeneDecksing



    Drugs & Compounds
    for RBFOX2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    RBFOX2 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for RBFOX2
    1 Novoseek chemical compound relationship for RBFOX2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    leucine 41.3 5 17392367 (1), 12610155 (1)

    Search CenterWatch for drugs/clinical trials and news about RBFOX2 / RFOX2 

    Transcripts
    for RBFOX2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for RBFOX2 gene (6 alternative transcripts): 
    NM_001031695.2  NM_001082576.1  NM_001082577.1  NM_001082578.1  NM_001082579.1  NM_014309.2  

    Unigene Cluster for RBFOX2:

    RNA binding protein, fox-1 homolog (C. elegans) 2
    Hs.282998  [show with all ESTs]
    Unigene Representative Sequence: NM_001031695
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000405409(uc021wok.1 uc003aol.4 uc003aoj.4 uc003aok.4 uc003aoh.4 uc003aom.4 uc010gwu.3 uc003aon.4 uc003aoo.4)
    ENST00000414461 ENST00000449924 ENST00000262829 ENST00000397303 ENST00000359369
    ENST00000463509 ENST00000416721 ENST00000495377 ENST00000438146 ENST00000408983
    ENST00000491982 ENST00000397305 ENST00000473487

    miRNA
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    8/172 QIAGEN miScript miRNA Assays for microRNAs that regulate RBFOX2 (see all 172):
    hsa-miR-520f hsa-miR-3916 hsa-miR-877* hsa-miR-1273d hsa-miR-637 hsa-miR-508-5p hsa-miR-200b hsa-miR-4326
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene shRNA RFP: RBFOX2
    OriGene siRNA: RBFOX2
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    Clone
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    Primer
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    Additional cDNA sequence: 

    AB649123.1 AF229058.1 AK055213.1 AK057055.1 AK091398.1 AK130730.1 AK291460.1 AK314632.1 
    AL009266.1 AL832604.2 AM419009.1 AY072786.1 AY960684.1 BC013115.1 BC025281.1 CR456559.1 
    DQ778625.1 

    24/28 DOTS entries (see all 28):

    DT.100797633  DT.97854063  DT.456414  DT.456415  DT.70105120  DT.100797637  DT.95175094  DT.120656013 
    DT.100797638  DT.95175103  DT.91743645  DT.120656014  DT.100809885  DT.91743647  DT.91743648  DT.100024752 
    DT.100797634  DT.308768  DT.95241100  DT.100672248  DT.120656248  DT.120656278  DT.308769  DT.40249057 

    24/559 AceView cDNA sequences (see all 559):

    BM845594 BU686396 BM838119 F12503 R34278 BE327850 AA401842 BQ007516 
    AI417875 CA442853 AI247529 AI215528 T33851 F11208 CB155806 AI192905 
    AI299713 F10123 F07933 AI951915 BE670066 BU585054 BM670051 Z44044 

    GeneLoc Exon Structure


    Expression
    for RBFOX2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RBFOX2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GTAATGAAGC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See RBFOX2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RBFOX2

    SOURCE GeneReport for Unigene cluster: Hs.282998
        SABiosciences Custom PCR Arrays for RBFOX2
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    In Situ
    Assay Products:     
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    Orthologs
    for RBFOX2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for RBFOX2 gene from 6/23 species (see all 23)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves RBFOX21 RNA binding protein, fox-1 homolog (C. elegans) 2 87.93(n)
    96.35(a)    		   418055  XM_416291.3  XP_416291.3 
    lizard
    (Anolis carolinensis)    		 Reptilia RBFOX26
    		 --
    		 98(a)
    		 1 ↔ 1
    		 5(21806836-21853248)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.146362 Xenopus laevis transcribed sequence with weak similarity more 74.84(n)    CD301062.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii rbfox26
    		 RNA binding protein, fox-1 homolog (C. elegans) 2
    		 74(a)
    		 1 ↔ 1
    		 6(271848-295086)
    fruit fly
    (Drosophila melanogaster)    		 Insecta A2bp11 Ataxin-2 binding protein 1 51(n)
    48.33(a)    		   39198  NM_168413.3  NP_729615.2 
    worm
    (Caenorhabditis elegans)    		 Secernentea fox-16
    asd-16
    (see all 3)    		 Sex determination protein fox-1
    Alternative Splicing Defective family member (asd-...
    (see all 3)    		 27(a)
    25(a)
    (see all 3)    		 many ↔ many
    many ↔ many
    (see all 3)    		 X(2445794-2450500)
    III(4197257-4202263)


    ENSEMBL Gene Tree for RBFOX2 (if available)
    TreeFam Gene Tree for RBFOX2 (if available) 

    Paralogs
    for RBFOX2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RBFOX2 gene
    RBFOX32  RBFOX12  
    10 SIMAP similar genes for RBFOX2 using alignment to 5 protein entries:     RFOX2_HUMAN (see all proteins):
    RBM9    DKFZp547L059    RBFOX1    A2BP1    RBFOX3    DAZL
    RBMY1A1    RBM38    SRSF5    HNRNPA1

    RBFOX2 for paralogs           About GeneDecksing



    Genomic Variants
    for RBFOX2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/3835 NCBI SNPs in RBFOX2 are shown (see all 3835)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 22 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs72856271,2
    		C,A,H,--19102089(+) GGCTTC/ATCATC 6 -- ds50012Minor allele frequency- A:0.00NS WA 238
    rs72854961,2
    		C,F,A,--19102105(+) TTAGAA/GCGTCT 6 -- ds50014Minor allele frequency- G:0.44WA CSA 124
    rs1125743581,2
    		--19102108(+) GAACGC/TCTCAC 6 -- ds50011Minor allele frequency- T:0.50CSA 2
    rs617446221,2
    		--19102627(+) GAGGAC/TGGGAG 6 -- ut311Minor allele frequency- T:0.01NS 74
    rs115420711,2
    		C,F,--19102673(+) ATCCCA/GTGTAA 6 -- ut311Minor allele frequency- G:0.08NS 72
    rs412832031,2
    		--19103076(+) TACTGC/TGAACA 6 -- ut310--------
    rs117054131,2
    		C,H--19103304(+) CCTCAA/GGTCAC 6 -- ut310--------
    rs622336171,2
    		C,F,--19104036(+) CTTCCC/TCACCC 6 -- ut311Minor allele frequency- T:0.04NA 120
    rs772870081,2
    		C,--19104545(+) CTCAAT/CTCAGA 6 -- ut312Minor allele frequency- C:0.14CSA WA 120
    rs748801251,2
    		--19104685(+) GCCTAT/AGGGCA 6 -- ut311Minor allele frequency- A:0.01WA 118

    HapMap Linkage Disequilibrium report for RBFOX2 (36134783 - 36384783 bp, first 250kb of RBFOX2)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for RBFOX2: --

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    Disorders / Diseases
    for RBFOX2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    RBFOX2 for disorders           About GeneDecksing

    OMIM gene information: 612149    OMIM disorders: --

    8 diseases for RBFOX2:    About MalaCards
    kaposi's sarcoma    sarcoma    hermaphroditism    conjunctivitis
    colon cancer    pharyngitis    ataxia    neuronitis

    1 Novoseek disease relationship for RBFOX2 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    kaposi sarcoma 53 1 12915555 (1)


    Export disorders for RBFOX2 gene to outside databases

    Publications
    for RBFOX2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RBFOX2 gene, integrated from 9 sources (see all 47):
    (articles sorted by number of sources associating them with RBFOX2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (2004)
    4. Reevaluating human gene annotation: a second-generation analysis of chromosome 22. (PubMed id 12529303)1, 2 Collins J.E.... Dunham I. (2003)
    5. A negative coregulator for the human ER. (PubMed id 11875103)1, 2 Norris J.D.... McDonnell D.P. (2002)
    6. The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I....O'Brien K.P. (1999)
    7. Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2. (PubMed id 18794351)1, 9 Zhang C....Zhang M.Q. (2008)
    8. RBFOX2 is an important regulator of mesenchymal tissue -specific splicing in both normal and cancer tissues. (PubMed id 23149937)1 Venables J.P....Chabot B. (2013)
    9. FOX-2 dependent splicing of ataxin-2 transcript is aff ected by ataxin-1 overexpression. (PubMed id 22666429)1 Welzel F....Krobitsch S. (2012)
    10. RBFOX2 promotes protein 4.1R exon 16 selection via U1 snRNP recruitment. (PubMed id 22083953)1 Huang S.C....Benz E.J. (2012)

    External Searches for RBFOX2 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  
      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing RBFOX2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23543 HGNC: 9906 AceView: RBM9 Ensembl:ENSG00000100320 euGenes: HUgn23543
    ECgene: RBFOX2 H-InvDB: RBFOX2

    Other Databases showing RBFOX2 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing RBFOX2 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RBFOX2 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for RBFOX2 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for RBFOX2 gene:
    Search GeneIP for patents involving RBFOX2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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