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Aliases for RBCK1 Gene

Aliases for RBCK1 Gene

  • RANBP2-Type And C3HC4-Type Zinc Finger Containing 1 2 3 5
  • Heme-Oxidized IRP2 Ubiquitin Ligase 1 2 3 4
  • Hepatitis B Virus X-Associated Protein 4 3 4
  • HBV-Associated Factor 4 3 4
  • RING Finger Protein 54 3 4
  • C20orf18 3 4
  • UBCE7IP3 3 4
  • HOIL-1 3 4
  • RNF54 3 4
  • XAP3 3 4
  • XAP4 3 4
  • RanBP-Type And C3HC4-Type Zinc Finger-Containing Protein 1 3
  • Ubiquitin Conjugating Enzyme 7 Interacting Protein 3 3
  • Ubiquitin-Conjugating Enzyme 7-Interacting Protein 3 4
  • RanBP-Type And C3HC4-Type Zinc Finger Containing 1 2
  • Chromosome 20 Open Reading Frame 18 2
  • RBCC Protein Interacting With PKC1 3
  • EC 6.3.2.- 4
  • ZRANB4 3
  • HOIL1 3
  • PBMEI 3
  • PGBM1 3
  • RBCK2 3

External Ids for RBCK1 Gene

Previous HGNC Symbols for RBCK1 Gene

  • C20orf18

Previous GeneCards Identifiers for RBCK1 Gene

  • GC20P000337
  • GC20P000388

Summaries for RBCK1 Gene

Entrez Gene Summary for RBCK1 Gene

  • The protein encoded by this gene is similar to mouse UIP28/UbcM4 interacting protein. Alternative splicing has been observed at this locus, resulting in distinct isoforms. [provided by RefSeq, Jul 2008]

GeneCards Summary for RBCK1 Gene

RBCK1 (RANBP2-Type And C3HC4-Type Zinc Finger Containing 1) is a Protein Coding gene. Diseases associated with RBCK1 include Polyglucosan Body Myopathy 1 With Or Without Immunodeficiency and Glycogen Storage Disease Iv. Among its related pathways are Immune System and Toll-Like receptor Signaling Pathways. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and ubiquitin-protein transferase activity. An important paralog of this gene is SHARPIN.

UniProtKB/Swiss-Prot for RBCK1 Gene

  • E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2L3/UBCM4, and then transfers it to substrates. Functions as an E3 ligase for oxidized IREB2 and both heme and oxygen are necessary for IREB2 ubiquitination. Promotes ubiquitination of TAB2 and IRF3 and their degradation by the proteasome. Component of the LUBAC complex which conjugates linear (Met-1-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis. Binds polyubiquitin of different linkage types.

Gene Wiki entry for RBCK1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RBCK1 Gene

Genomics for RBCK1 Gene

Regulatory Elements for RBCK1 Gene

Enhancers for RBCK1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH20F000430 0.9 Ensembl ENCODE 20.4 +25.8 25803 6.2 PKNOX1 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 ZNF143 RBCK1 NRSN2 NRSN2-AS1 TRIB3 CSNK2A1 TBC1D20 GC20P000435
GH20F000406 0.2 ENCODE 14.8 +1.1 1091 3.8 HDGF PKNOX1 MLX ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 ZNF143 RBCK1 TBC1D20 GC20P000435
GH20F000368 1.4 FANTOM5 Ensembl ENCODE 13.8 -35.0 -34978 8.0 ARNT CREB3L1 MLX ZFP64 ARID4B SIN3A DMAP1 YY1 SLC30A9 ZNF766 TBC1D20 TRIB3 ENSG00000272874 DEFB129 DEFB126 DEFB125 RBCK1 SRXN1 ENSG00000206797 CSNK2A1
GH20F000377 0.2 ENCODE 12.7 -26.4 -26433 6.5 MLX CREB3L1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF548 ZNF263 TRIB3 TBC1D20 RBCK1 NRSN2 NRSN2-AS1 ENSG00000229728 SOX12 ACTG1P3 GC20P000385 GC20P000387
GH20F000477 0.2 ENCODE 12.5 +70.8 70822 1.4 SOX13 ELF3 CTCF ZNF792 ARID4B ZNF175 RAD21 DNMT3B TEAD3 ZNF143 ENSG00000206797 RBCK1 NRSN2 NRSN2-AS1 TRIB3 TBC1D20 CSNK2A1 GC20P000482 GC20P000462
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around RBCK1 on UCSC Golden Path with GeneCards custom track

Promoters for RBCK1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000396302 902 2401 HDGF PKNOX1 MLX ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1

Genomic Location for RBCK1 Gene

Chromosome:
20
Start:
407,498 bp from pter
End:
430,966 bp from pter
Size:
23,469 bases
Orientation:
Plus strand

Genomic View for RBCK1 Gene

Genes around RBCK1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RBCK1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RBCK1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RBCK1 Gene

Proteins for RBCK1 Gene

  • Protein details for RBCK1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BYM8-HOIL1_HUMAN
    Recommended name:
    RanBP-type and C3HC4-type zinc finger-containing protein 1
    Protein Accession:
    Q9BYM8
    Secondary Accessions:
    • O95623
    • Q86SL2
    • Q96BS3
    • Q9BYM9

    Protein attributes for RBCK1 Gene

    Size:
    510 amino acids
    Molecular mass:
    57572 Da
    Quaternary structure:
    • Forms homodimers in vitro (By similarity). Component of the LUBAC complex (linear ubiquitin chain assembly complex) which consists of SHARPIN, RBCK1 and RNF31. LUBAC has a MW of approximative 600 kDa suggesting a heteromultimeric assembly of its subunits. Interacts with beta-I-type (PRKCB1) and zeta-type protein kinase C (PRKCZ) and with UBE2L3. Interacts with PRKCH. Interacts with the HBV pX/HBx protein, which is required to activate transcription of the viral genome. Isoform 1 and isoform 2 interact with IREB2 only in iron-rich conditions. Associates with the TNF-R1 signaling complex (TNF-RSC) in a stimulation-dependent manner. Interacts with EYA1, TAB2, TAB3, MAP3K7 TRAF6 and RIPK1. Interacts with IRF3.
    SequenceCaution:
    • Sequence=AAH15219.2; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for RBCK1 Gene

    Alternative splice isoforms for RBCK1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for RBCK1 Gene

Post-translational modifications for RBCK1 Gene

  • Auto-ubiquitinated. Auto-ubiquitination leads to degradation by the proteasome (By similarity).
  • Phosphorylated. In vitro, phosphorylation inhibits auto-ubiquitination activity (By similarity).
  • Ubiquitination at Lys 29, Lys 158, Lys 174, Lys 254, and Lys 342
  • Modification sites at PhosphoSitePlus

Antibody Products

  • Abcam antibodies for RBCK1

No data available for DME Specific Peptides for RBCK1 Gene

Domains & Families for RBCK1 Gene

Gene Families for RBCK1 Gene

Graphical View of Domain Structure for InterPro Entry

Q9BYM8

UniProtKB/Swiss-Prot:

HOIL1_HUMAN :
  • The RanBP2-type zinc finger, also called Npl4 zinc finger (NZF), mediates binding to Met-1-linked polyubiquitins.
  • Contains 1 IBR-type zinc finger.
Domain:
  • The RanBP2-type zinc finger, also called Npl4 zinc finger (NZF), mediates binding to Met-1-linked polyubiquitins.
  • The UBL domain mediates association with RNF31 via interaction with its UBA domain.
  • Contains 1 ubiquitin-like domain.
Similarity:
  • Contains 1 IBR-type zinc finger.
  • Contains 1 RanBP2-type zinc finger.
  • Contains 2 RING-type zinc fingers.
genes like me logo Genes that share domains with RBCK1: view

Function for RBCK1 Gene

Molecular function for RBCK1 Gene

UniProtKB/Swiss-Prot Function:
E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2L3/UBCM4, and then transfers it to substrates. Functions as an E3 ligase for oxidized IREB2 and both heme and oxygen are necessary for IREB2 ubiquitination. Promotes ubiquitination of TAB2 and IRF3 and their degradation by the proteasome. Component of the LUBAC complex which conjugates linear (Met-1-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis. Binds polyubiquitin of different linkage types.
UniProtKB/Swiss-Prot Induction:
By viral transfection.

Enzyme Numbers (IUBMB) for RBCK1 Gene

Gene Ontology (GO) - Molecular Function for RBCK1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004842 ubiquitin-protein transferase activity TAS --
GO:0005515 protein binding IPI 16643902
GO:0008270 zinc ion binding IEA --
GO:0016874 ligase activity IEA --
GO:0043130 ubiquitin binding IDA 21455181
genes like me logo Genes that share ontologies with RBCK1: view
genes like me logo Genes that share phenotypes with RBCK1: view

Human Phenotype Ontology for RBCK1 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for RBCK1 Gene

MGI Knock Outs for RBCK1:

Animal Model Products

miRNA for RBCK1 Gene

miRTarBase miRNAs that target RBCK1

Inhibitory RNA Products

Flow Cytometry Products

No data available for Transcription Factor Targets and HOMER Transcription for RBCK1 Gene

Localization for RBCK1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RBCK1 Gene COMPARTMENTS Subcellular localization image for RBCK1 gene
Compartment Confidence
cytosol 5
nucleus 3

Gene Ontology (GO) - Cellular Components for RBCK1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005829 cytosol TAS --
GO:0071797 LUBAC complex IDA 17006537
genes like me logo Genes that share ontologies with RBCK1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for RBCK1 Gene

Pathways & Interactions for RBCK1 Gene

genes like me logo Genes that share pathways with RBCK1: view

Gene Ontology (GO) - Biological Process for RBCK1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000209 protein polyubiquitination TAS --
GO:0007249 I-kappaB kinase/NF-kappaB signaling TAS --
GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway TAS --
GO:0016032 viral process IEA --
GO:0032088 negative regulation of NF-kappaB transcription factor activity IDA 17449468
genes like me logo Genes that share ontologies with RBCK1: view

No data available for SIGNOR curated interactions for RBCK1 Gene

Transcripts for RBCK1 Gene

Unigene Clusters for RBCK1 Gene

RanBP-type and C3HC4-type zinc finger containing 1:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RBCK1 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b · 2c ^ 3a · 3b · 3c · 3d ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10a · 10b · 10c ^ 11a · 11b ·
SP1: - -
SP2:
SP3: - - - - - - - - - -
SP4: - - - - - -
SP5:
SP6: - - - - - - - - - - -
SP7: - - - -
SP8:
SP9:
SP10:
SP11: - -
SP12: - - - - - - - -
SP13:
SP14: - - - - - - - -
SP15: - - - - - - - -
SP16:
SP17: - - -

ExUns: 11c ^ 12a · 12b ^ 13 ^ 14a · 14b ^ 15a · 15b ^ 16a · 16b
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8: -
SP9:
SP10: -
SP11:
SP12:
SP13:
SP14:
SP15:
SP16: -
SP17:

Relevant External Links for RBCK1 Gene

GeneLoc Exon Structure for
RBCK1
ECgene alternative splicing isoforms for
RBCK1

Expression for RBCK1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for RBCK1 Gene

Protein differential expression in normal tissues from HIPED for RBCK1 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (17.7), Lung (10.7), and CD8 Tcells (6.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for RBCK1 Gene



Protein tissue co-expression partners for RBCK1 Gene

NURSA nuclear receptor signaling pathways regulating expression of RBCK1 Gene:

RBCK1

SOURCE GeneReport for Unigene cluster for RBCK1 Gene:

Hs.247280
genes like me logo Genes that share expression patterns with RBCK1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RBCK1 Gene

Orthologs for RBCK1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RBCK1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia RBCK1 34 35
  • 99.67 (n)
cow
(Bos Taurus)
Mammalia C20ORF18 35
  • 95 (a)
OneToOne
RBCK1 34
  • 90.92 (n)
dog
(Canis familiaris)
Mammalia RBCK1 34 35
  • 91.9 (n)
mouse
(Mus musculus)
Mammalia Rbck1 34 16 35
  • 87.8 (n)
rat
(Rattus norvegicus)
Mammalia Rbck1 34
  • 87.07 (n)
oppossum
(Monodelphis domestica)
Mammalia RBCK1 35
  • 78 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia RBCK1 35
  • 64 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100491300 34
  • 67.2 (n)
zebrafish
(Danio rerio)
Actinopterygii rbck1 34 35
  • 58.5 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 48 (a)
OneToMany
Species where no ortholog for RBCK1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RBCK1 Gene

ENSEMBL:
Gene Tree for RBCK1 (if available)
TreeFam:
Gene Tree for RBCK1 (if available)

Paralogs for RBCK1 Gene

Paralogs for RBCK1 Gene

(1) SIMAP similar genes for RBCK1 Gene using alignment to 9 proteins:

genes like me logo Genes that share paralogs with RBCK1: view

Variants for RBCK1 Gene

Sequence variations from dbSNP and Humsavar for RBCK1 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs566912235 Polyglucosan body myopathy 1 with or without immunodeficiency (PGBM1) [MIM:615895], Pathogenic 427,443(+) TGTCA(A/G)TGAGT nc-transcript-variant, reference, missense
VAR_071385 Polyglucosan body myopathy 1 with or without immunodeficiency (PGBM1) [MIM:615895]
rs587777561 Pathogenic 420,904(+) ACCTG(C/T)AGCAC intron-variant, nc-transcript-variant, downstream-variant-500B, reference, stop-gained
rs727503762 Pathogenic 419,439(+) GGGGG(C/T)AGCCA nc-transcript-variant, reference, synonymous-codon, stop-gained
rs727503763 Pathogenic 409,979(+) TGCCC(-/CT)GAGTG intron-variant, nc-transcript-variant, reference, frameshift-variant, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for RBCK1 Gene

Variant ID Type Subtype PubMed ID
dgv4219n100 CNV gain 25217958
esv3644952 CNV gain 21293372
esv3644953 CNV gain 21293372
esv3644956 CNV gain 21293372
esv3893263 CNV loss 25118596
nsv1056266 CNV gain 25217958
nsv1066598 CNV gain 25217958
nsv458841 CNV loss 19166990
nsv458842 CNV loss 19166990
nsv510479 OTHER sequence alteration 20534489
nsv510777 CNV deletion 20534489
nsv585170 CNV loss 21841781
nsv585171 CNV loss 21841781

Variation tolerance for RBCK1 Gene

Residual Variation Intolerance Score: 15.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.62; 13.21% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RBCK1 Gene

Human Gene Mutation Database (HGMD)
RBCK1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
RBCK1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RBCK1 Gene

Disorders for RBCK1 Gene

MalaCards: The human disease database

(3) MalaCards diseases for RBCK1 Gene - From: OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
polyglucosan body myopathy 1 with or without immunodeficiency
  • pgbmi
glycogen storage disease iv
  • amylopectinosis
branchiootic syndrome
  • branchiootic syndrome 1
- elite association - COSMIC cancer census association via MalaCards
Search RBCK1 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

HOIL1_HUMAN
  • Polyglucosan body myopathy 1 with or without immunodeficiency (PGBM1) [MIM:615895]: A disease characterized by polyglucosan storage myopathy associated with early-onset progressive muscle weakness and progressive dilated cardiomyopathy, which may necessitate cardiac transplant in severe cases. Some patients present with severe immunodeficiency, invasive bacterial infections and chronic autoinflammation. {ECO:0000269 PubMed:23104095, ECO:0000269 PubMed:23798481}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Relevant External Links for RBCK1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
RBCK1
genes like me logo Genes that share disorders with RBCK1: view

No data available for Genatlas for RBCK1 Gene

Publications for RBCK1 Gene

  1. Negative feedback regulation of cellular antiviral signaling by RBCK1-mediated degradation of IRF3. (PMID: 18711448) Zhang M. … Shu H.B. (Cell Res. 2008) 3 4 22 64
  2. Polyglucosan body myopathy caused by defective ubiquitin ligase RBCK1. (PMID: 23798481) Nilsson J. … Oldfors A. (Ann. Neurol. 2013) 3 4 64
  3. A non-canonical UBA-UBL interaction forms the linear-ubiquitin-chain assembly complex. (PMID: 22430200) Yagi H. … Kato K. (EMBO Rep. 2012) 3 4 64
  4. Solution structure of the E3 ligase HOIL-1 Ubl domain. (PMID: 22517668) Beasley S.A. … Shaw G.S. (Protein Sci. 2012) 3 4 64
  5. Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency. (PMID: 23104095) Boisson B. … Picard C. (Nat. Immunol. 2012) 3 4 64

Products for RBCK1 Gene

Sources for RBCK1 Gene

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