RBBP5 Gene
protein-coding GIFtS: 53
GCID: GC01M205055
|
|
retinoblastoma binding protein 5(Previous name: retinoblastoma-binding protein 5 )
| |
Aliases for RBBP5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Retinoblastoma Binding Protein 51 2 | | Retinoblastoma-Binding Protein RBQ-32 3 | | RBQ31 2 3 5 | | RBBP-52 3 | | SWD11 2 | | SWD1, Set1c WD40 Repeat Protein, Homolog2 | | Retinoblastoma-Binding Protein 51 2 | | |
Export aliases for RBBP5 gene to outside databasesPrevious GC identifers: GC01M202782 GC01M200517 GC01M201415 GC01M202233 GC01M201787 GC01M203321 GC01M176220 |
Summaries for RBBP5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for RBBP5: This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeatproteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. Itinteracts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Threealternatively spliced transcript variants that encode different protein isoforms have been described for this gene.(provided by RefSeq, Jul 2010) UniProtKB/Swiss-Prot: RBBP5_HUMAN, Q15291Function: In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along theneural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including thatmediated by retinoic acid (By similarity). As part of the MLL1/MLL complex, involved in mono-, di- and trimethylationat 'Lys-4' of histone H3. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptionalactivation Gene Wiki entry for RBBP5
|
Genomic Views for RBBP5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004487.19
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the RBBP5 gene promoter: GR RFX1 GR-beta Lmo2 CUTL1 XBP-1 POU6F1 (c2) Evi-1 NRF-2 GR-alpha Other transcription factors
Search SABiosciences Chromatin IP Primers for RBBP5
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RBBP5 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q32 Ensembl cytogenetic band: 1q32.1 HGNC cytogenetic band: 1q32RBBP5 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M205055: view genomic region
(about GC identifiers)
Start:
|
205,055,270 bp from pter |
End:
|
205,091,150 bp from pter |
Size:
|
35,881 bases |
Orientation:
|
minus strand |
|
Proteins for RBBP5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: RBBP5_HUMAN, Q15291 (See
protein sequence)Recommended Name: Retinoblastoma-binding protein 5 Size: 538 amino acids; 59153 Da
Subunit: Component of the SET1 complex, at least composed of the catalytic subunit (SETD1A or SETD1B), WDR5, WDR82,RBBP5, ASH2L/ASH2, CXXC1/CFP1, HCFC1 and DPY30. Core component of several methyltransferase-containing complexesincluding MLL1/MLL, MLL2/3 (also named ASCOM complex) and MLL4/WBP7. Each complex is at least composed of ASH2L,RBBP5, WDR5, DPY30, one or more specific histone methyltransferases (MLL, MLL2/ALR, MLL3 and MLL4/WBP7), and thefacultative components PAGR1, BAP18, CHD8, E2F6, HCFC1, HCFC2, HSP70, INO80C, KDM6A, KANSL1, LAS1L, MAX, MCRS1, MEN1,MGA, MYST1/MOF, NCOA6, PAXIP1/PTIP, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6,TAF7, TAF9, TEX10 and alpha- and beta-tubulin. Interacts with WDR5 and ASH2L; the interaction is direct. Interactswith WDR82 and SETD1A
Subcellular location: Nucleus
1 PDB 3D structure from and Proteopedia for RBBP5:3P4F (3D)
 
Secondary accessions: A8K272 Q7Z6D8 Q8NDZ7Alternative splicing: 2 isoforms: Q15291-1 Q15291-2 (Contains a phosphoserine at position 490)Explore the universe of human proteins at neXtProt for RBBP5: NX_Q15291
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q15291 RBBP5 Protein expression data from MOPED and PaxDb: About this image 
 REFSEQ proteins (3 alternative transcripts):
NP_001180201.1 NP_001180202.1 NP_005048.2 ENSEMBL proteins: ENSP00000264515 ENSP00000356132 Human Recombinant Protein Products for RBBP5:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
RBBP5 for ontologies About GeneDecksing
RBBP5 Antibody Products: Assay Products for RBBP5: |
Protein
Domains / Families for RBBP5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RBBP5 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q15291ProtoNet protein and cluster: Q15291 UniProtKB/Swiss-Prot: RBBP5_HUMAN, Q15291Similarity: Contains 6 WD repeats |
Function for RBBP5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Molecular Function: UniProtKB/Swiss-Prot Summary: RBBP5_HUMAN, Q15291Function: In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along theneural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including thatmediated by retinoic acid (By similarity). As part of the MLL1/MLL complex, involved in mono-, di- and trimethylationat 'Lys-4' of histone H3. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptionalactivation Genatlas biochemistry entry for RBBP5:RB1 binding nuclear protein 5,with homology to TF2B
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
RBBP5 for ontologies About GeneDecksing
Animal Models:
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RBBP5 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RBBP5 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): RBBP5 (NM_005057) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RBBP5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RBBP5  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBBP5 |
|
Pathways & Interactions for RBBP5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Chromatin Regulation / Acetylation | |
Pathway sources See GeneCards unified pathways Show all pathways
1
Cell Signaling Technology (CST) Pathway for RBBP5
RBBP5 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RBBP5
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/875 Interacting proteins for RBBP5 (Q152911, 2, 3 ENSP000002645154) via UniProtKB, MINT, STRING, and/or I2D (see all 875)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
RBBP5 for ontologies About GeneDecksing
|
Drugs & Compounds for RBBP5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for RBBP5 Search CenterWatch for drugs/clinical trials and news about RBBP5 
|
Transcripts for RBBP5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for RBBP5 gene (3 alternative transcripts): NM_001193272.1 NM_001193273.1 NM_005057.3 Unigene Cluster for RBBP5: Retinoblastoma binding protein 5 Hs.519230 [show with all ESTs]Unigene Representative Sequence: NM_0050573 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000264515(uc010prd.2 uc010pre.2 uc001hbu.2) ENST00000367164(uc001hbv.2) ENST00000484379
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RBBP5 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RBBP5 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): RBBP5 (NM_005057) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RBBP5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RBBP5  |
Additional cDNA sequence: AK290137.1 AK296978.1 AK297540.1 BC037284.2 BC053856.1 BC075059.2 BC075060.2 X85134.1 6 DOTS entries: DT.100814660 DT.91793814 DT.101972968 DT.121330413 DT.99993441 DT.121330352 24/100 AceView cDNA sequences (see all 100): BM457775 AL119169 BE378702 BP871752 BP357482 CD518019 CD559083 BC075059 CF138358 AA488959 BC075060 BX475888 BM841893 BU430770 AA489300 BG177847 BX096879 BM452621 AW505316 BC053856 BU627762 BC037284 AA410788 AI056177 GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for RBBP5 (see all 7) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | ^ | 14a | · | 14b | · | 14c | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for RBBP5
|
Expression for RBBP5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RBBP5 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: --
 About this image See RBBP5 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for RBBP5
SOURCE GeneReport for Unigene cluster: Hs.519230
UniProtKB/Swiss-Prot: RBBP5_HUMAN, Q15291Tissue specificity: Ubiquitously expressed SABiosciences Expression via Pathway-Focused PCR Arrays including RBBP5: | Epigenetic Chromatin Modification Enzymes in human mouse rat | | Polycomb & Trithorax Complexes in human mouse rat |
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RBBP5 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RBBP5 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RBBP5 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RBBP5 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBBP5 |
Orthologs for RBBP5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for RBBP5 gene from 10/35 species (see all 35) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
mouse (Mus musculus) |
Mammalia |
Rbbp51 , 5 |
retinoblastoma binding protein 51, 5 |
92.63(n)1 99.07(a)1 |
  |
1 (57.24 cM)5 2134641 NM_172517.21 NP_766105.21 1324773675 |
chicken (Gallus gallus) |
Aves |
RBBP51 |
retinoblastoma binding protein 5 |
83.52(n) 97.58(a) |
  |
419826 NM_001030914.1 NP_001026085.1 |
lizard (Anolis carolinensis) |
Reptilia |
RBBP56 |
-- |
91(a) |
1 ↔ 1 |
4(116301007-116330842) |
African clawed frog (Xenopus laevis) |
Amphibia |
Xl.71002 |
Xenopus laevis transcribed sequence with strong similarity more |
78.36(n) |
  |
BX847136.1 |
zebrafish (Danio rerio) |
Actinopterygii |
zgc560782 |
similar to retinoblastoma binding protein 5 |
74.28(n) |
  |
393215 BC047822.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
CG64343 CG55851 |
CG55851 |
71(a) (best of 2)3 60.52(n)1 68.53(a)1 |
  |
77B43 402391 NM_140952.21 NP_649209.11 |
worm (Caenorhabditis elegans) |
Secernentea |
F21H12.11 , 3 |
Protein F21H12.11 |
41(a)3 53.78(n)1 43.84(a)1 |
  |
II(6097788-6101835)3 1740191 NM_062821.71 NP_495222.21 |
baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes |
SWD1(YAR003W)4 SWD11 |
Subunit of the COMPASS (Set1C) complex, which methylates more4 Swd1p1 |
46.13(n)1 33.98(a)1 |
  |
1(155005-156285)4 8512651, 4 NP_009403.11, 4 |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
AT3G210601 |
transducin/WD40 domain-containing protein |
51.45(n) 42.09(a) |
  |
821658 NM_113000.5 NP_188743.3 |
rice (Oryza sativa) |
Liliopsida |
Os03g02079001 |
hypothetical protein |
48.73(n) 41.77(a) |
  |
4332006 NM_001055863.1 NP_001049328.1 |
ENSEMBL Gene Tree for RBBP5 (if available) TreeFam Gene Tree for RBBP5 (if available)  |
Paralogs for RBBP5 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for RBBP5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 1 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for RBBP5 (205055270 - 205091150 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for RBBP5 1 Indel: 58358  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RBBP5 |
|
Disorders
/ Diseases for RBBP5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RBBP5 for disorders About GeneDecksing
OMIM gene information: 600697
OMIM disorders: --
6 diseases for RBBP5: About MalaCardsretinoblastoma wiskott-aldrich syndrome intrahepatic cholangiocarcinoma cholangiocarcinoma breast cancer leukemia Export disorders for RBBP5 gene to outside databases
|
Publications for RBBP5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RBBP5 gene, integrated from 9 sources (see all 67): (articles sorted by number of sources associating them with RBBP5) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Molecular cloning of a human protein that binds to the retinoblastoma protein and chromosomal mapping. (PubMed id 7558034)1, 2, 3 Saijo M.... Taya Y. (1995)
- On the mechanism of multiple lysine methylation by th e human mixed lineage leukemia protein-1 (MLL1) core complex. (PubMed id 19556245)1, 2 Patel A....Cosgrove M.S. (2009)
- Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes. (PubMed id 17998332)1, 2 Lee J.H. and Skalnik D.G. (2008)
- Molecular regulation of H3K4 trimethylation by Wdr82, a component of human Set1/COMPASS. (PubMed id 18838538)1, 2 Wu M....Shilatifard A. (2008)
- Identification and characterization of the human Set1B histone H3- Lys4 methyltransferase complex. (PubMed id 17355966)1, 2 Lee J.-H.... Skalnik D.G. (2007)
- PTIP Associates with MLL3- and MLL4-containing Histone H3 Lysine 4 Methyltransferase Complex. (PubMed id 17500065)1, 2 Cho Y.W.... Ge K. (2007)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- CpG-binding protein (CXXC finger protein 1) is a component of the mammalian Set1 histone H3-Lys4 methyltransferase complex, the analogue of the yeast Set1/COMPASS complex. (PubMed id 16253997)1, 2 Lee J.-H. and Skalnik D.G. (2005)
- Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. (PubMed id 15960975)1, 2 Dou Y.... Roeder R.G. (2005)
- Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression. (PubMed id 15199122)1, 2 Yokoyama A.... Cleary M.L. (2004)
|
External Searches for RBBP5 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing RBBP5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RBBP5 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RBBP5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
|
About This Section
| Patent Information for RBBP5 gene: Search GeneIP for patents involving RBBP5
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for RBBP5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory) About This Section
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| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for RBBP5 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RBBP5 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RBBP5 | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for RBBP5 | | OriGene 3'-UTR Clone for RBBP5 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RBBP5 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RBBP5 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for RBBP5 | | OriGene Custom Protein Services for RBBP5 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RBBP5 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RBBP5 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RBBP5 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RBBP5 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RBBP5 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RBBP5 |
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| Antibodies & Assays for RBBP5  |
| | | Search Tocris compounds for RBBP5 |
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 | | RBBP5 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBBP5 |
|  |  |  |  | | | ThermoFisher Antibodies for RBBP5 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RBBP5 |
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