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Aliases for RBAK-RBAKDN Gene

Aliases for RBAK-RBAKDN Gene

  • RBAK-RBAKDN Readthrough 2 3 5
  • RBAK-LOC389458 Readthrough 3
  • RBAK-LOC389458 3

External Ids for RBAK-RBAKDN Gene

Previous GeneCards Identifiers for RBAK-RBAKDN Gene

  • GC07P005024
  • GC07P005025

Summaries for RBAK-RBAKDN Gene

Entrez Gene Summary for RBAK-RBAKDN Gene

  • This locus represents naturally occurring read-through transcription between the neighboring RBAK (RB-associated KRAB zinc finger) and LOC389458 (hypothetical LOC389458) genes on chromosome 7. The read-through transcript encodes a protein that shares sequence identity with the upstream gene product but its C-terminal region is distinct due to frameshifts relative to the downstream gene. [provided by RefSeq, Mar 2011]

GeneCards Summary for RBAK-RBAKDN Gene

RBAK-RBAKDN (RBAK-RBAKDN Readthrough) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ENSG00000283179.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RBAK-RBAKDN Gene

Genomics for RBAK-RBAKDN Gene

Regulatory Elements for RBAK-RBAKDN Gene

Enhancers for RBAK-RBAKDN Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F004973 0.6 ENCODE 0.4 -9.3 -9266 2.0 HDGF PKNOX1 ARNT CREB3L1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZNF207 RNF216P1 WIPI2 RBAK-RBAKDN
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around RBAK-RBAKDN on UCSC Golden Path with GeneCards custom track

Genomic Location for RBAK-RBAKDN Gene

Chromosome:
7
Start:
4,983,718 bp from pter
End:
5,073,223 bp from pter
Size:
89,506 bases
Orientation:
Plus strand

Genomic View for RBAK-RBAKDN Gene

Genes around RBAK-RBAKDN on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RBAK-RBAKDN Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RBAK-RBAKDN Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RBAK-RBAKDN Gene

Proteins for RBAK-RBAKDN Gene

  • Protein details for RBAK-RBAKDN Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A0A6YYG8
    Recommended name:
    Protein RBAK-RBAKDN
    Protein Accession:
    A0A0A6YYG8

    Protein attributes for RBAK-RBAKDN Gene

    Size:
    113 amino acids
    Molecular mass:
    12251 Da
    Quaternary structure:
    No Data Available
  • Protein details for RBAK-RBAKDN Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    I3L0D1
    Recommended name:
    HCG1647537, isoform CRA_b
    Protein Accession:
    I3L0D1

    Protein attributes for RBAK-RBAKDN Gene

    Size:
    243 amino acids
    Molecular mass:
    27466 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RBAK-RBAKDN Gene

Post-translational modifications for RBAK-RBAKDN Gene

No Post-translational modifications

Other Protein References for RBAK-RBAKDN Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RBAK-RBAKDN Gene

Domains & Families for RBAK-RBAKDN Gene

Protein Domains for RBAK-RBAKDN Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RBAK-RBAKDN: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RBAK-RBAKDN Gene

Function for RBAK-RBAKDN Gene

Animal Model Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RBAK-RBAKDN Gene

Localization for RBAK-RBAKDN Gene

Gene Ontology (GO) - Cellular Components for RBAK-RBAKDN Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
genes like me logo Genes that share ontologies with RBAK-RBAKDN: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for RBAK-RBAKDN Gene

Pathways & Interactions for RBAK-RBAKDN Gene

SuperPathways for RBAK-RBAKDN Gene

No Data Available

Interacting Proteins for RBAK-RBAKDN Gene

Gene Ontology (GO) - Biological Process for RBAK-RBAKDN Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with RBAK-RBAKDN: view

No data available for Pathways by source and SIGNOR curated interactions for RBAK-RBAKDN Gene

Transcripts for RBAK-RBAKDN Gene

mRNA/cDNA for RBAK-RBAKDN Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RBAK-RBAKDN Gene

No ASD Table

Relevant External Links for RBAK-RBAKDN Gene

GeneLoc Exon Structure for
RBAK-RBAKDN
ECgene alternative splicing isoforms for
RBAK-RBAKDN

Expression for RBAK-RBAKDN Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from MaxQB and MOPED for RBAK-RBAKDN Gene



No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for RBAK-RBAKDN Gene

Orthologs for RBAK-RBAKDN Gene

This gene was present in the common ancestor of mammals.

Orthologs for RBAK-RBAKDN Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia RBAK-RBAKDN 35
  • 31 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp663 35
  • 7 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 35
  • 5 (a)
ManyToMany
Species where no ortholog for RBAK-RBAKDN was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RBAK-RBAKDN Gene

ENSEMBL:
Gene Tree for RBAK-RBAKDN (if available)
TreeFam:
Gene Tree for RBAK-RBAKDN (if available)

Paralogs for RBAK-RBAKDN Gene

Variants for RBAK-RBAKDN Gene

Sequence variations from dbSNP and Humsavar for RBAK-RBAKDN Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs193921102 Uncertain significance 5,065,058(+) CCAAA(A/T)GGGGA intron-variant, reference, missense
rs10234867 -- 5,050,312(+) acctt(C/T)agcac intron-variant
rs10238244 -- 5,056,687(+) TGAGA(C/T)GTTTG intron-variant
rs10239712 -- 5,052,058(+) ATATT(A/G)GATAC intron-variant
rs10244918 -- 5,068,087(+) GGAAA(C/T)CATGG intron-variant, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for RBAK-RBAKDN Gene

Variant ID Type Subtype PubMed ID
dgv3482n106 OTHER inversion 24896259
dgv6239n100 CNV gain 25217958
dgv6240n100 CNV gain 25217958
esv2667035 CNV deletion 23128226
nsv1019120 CNV loss 25217958
nsv436904 CNV insertion 17901297
nsv605981 CNV loss 21841781
nsv8033 CNV loss 18304495
nsv950800 CNV deletion 24416366
nsv966749 CNV duplication 23825009
nsv966924 CNV duplication 23825009

Variation tolerance for RBAK-RBAKDN Gene

Residual Variation Intolerance Score: 64.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.47; 82.10% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RBAK-RBAKDN Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RBAK-RBAKDN

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RBAK-RBAKDN Gene

Disorders for RBAK-RBAKDN Gene

Relevant External Links for RBAK-RBAKDN

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
RBAK-RBAKDN

No disorders were found for RBAK-RBAKDN Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RBAK-RBAKDN Gene

Publications for RBAK-RBAKDN Gene

  1. Toward a complete human genome sequence. (PMID: 9847074) Sulston J.E. … Waterston R. (Genome Res. 1998) 3 64
  2. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3 64

Products for RBAK-RBAKDN Gene

Sources for RBAK-RBAKDN Gene

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