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RAX2 Gene

protein-coding   GIFtS: 46
GCID: GC19M003769

Retina And Anterior Neural Fold Homeobox 2

(Previous name: retina and anterior neural fold homeobox like 1)
(Previous symbol: RAXL1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Retina And Anterior Neural Fold Homeobox 21 2     Q50-Type Retinal Homeobox Protein2 3
RAXL11 2 3 5     ARMD62 5
QRX2 3 5     CORD112 5
Retina And Anterior Neural Fold Homeobox Like 11 2     Retina And Anterior Neural Fold Homeobox Protein 22
Retina And Anterior Neural Fold Homeobox-Like Protein 12 3     

External Ids:    HGNC: 182861   Entrez Gene: 848392   Ensembl: ENSG000001739767   OMIM: 6103625   UniProtKB: Q96IS33   

Export aliases for RAX2 gene to outside databases

Previous GC identifers: GC19M003449 GC19M003498 GC19M003499


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RAX2 Gene:
This gene encodes a homeodomain-containing protein that plays a role in eye development. Mutation of this gene
causes age-related macular degeneration type 6, an eye disorder resulting in accumulations of protein and lipid
beneath the retinal pigment epithelium and within the Bruch's membrane. Defects in this gene can also cause
cone-rod dystrophy type 11, a disease characterized by the initial degeneration of cone photoreceptor cells and
resulting in loss of color vision and visual acuity, followed by the degeneration of rod photoreceptor cells,
which progresses to night blindness and the loss of peripheral vision. (provided by RefSeq, Jul 2008)

GeneCards Summary for RAX2 Gene:
RAX2 (retina and anterior neural fold homeobox 2) is a protein-coding gene. Diseases associated with RAX2 include cone-rod dystrophy 11, and age-related macular degeneration 6. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ALX1.

UniProtKB/Swiss-Prot: RAX2_HUMAN, Q96IS3
Function: May be involved in modulating the expression of photoreceptor specific genes. Binds to the Ret-1 and
Bat-1 element within the rhodopsin promoter




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000019.10  NT_011295.12  NC_018930.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RAX2 gene promoter:
         GR   AML1a   p300   AREB6   CREB   PPAR-gamma1   deltaCREB   PPAR-gamma2   GR-alpha   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRAX2 promoter sequence
   Search Chromatin IP Primers for RAX2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RAX2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.3   Ensembl cytogenetic band:  19p13.3   HGNC cytogenetic band: 19p13.3

RAX2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAX2 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M003769:  view genomic region     (about GC identifiers)

Start:
3,769,087 bp from pter      End:
3,772,233 bp from pter
Size:
3,147 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RAX2_HUMAN, Q96IS3 (See protein sequence)
Recommended Name: Retina and anterior neural fold homeobox protein 2  
Size: 184 amino acids; 20086 Da
Subunit: Interacts with CRX

Explore the universe of human proteins at neXtProt for RAX2: NX_Q96IS3

Explore proteomics data for RAX2 at MOPED


See RAX2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_116142.1  
ENSEMBL proteins: 
 ENSP00000450687   ENSP00000450456  

RAX2 Human Recombinant Protein Products:

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RAX2 Assay Products:

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Cloud-Clone Corp. ELISAs for RAX2
Cloud-Clone Corp. CLIAs for RAX2


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
PRD: Homeoboxes / PRD class

3 InterPro protein domains:
 IPR017970 Homeobox_CS
 IPR001356 Homeobox_dom
 IPR009057 Homeodomain-like

Graphical View of Domain Structure for InterPro Entry Q96IS3

ProtoNet protein and cluster: Q96IS3

UniProtKB/Swiss-Prot: RAX2_HUMAN, Q96IS3
Domain: The Homeobox transactivates the Ret-1 element in the presence of CRX and NRL
Similarity: Contains 1 homeobox DNA-binding domain


RAX2 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: RAX2_HUMAN, Q96IS3
Function: May be involved in modulating the expression of photoreceptor specific genes. Binds to the Ret-1 and
Bat-1 element within the rhodopsin promoter

     Gene Ontology (GO): 3 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003677DNA binding ----
GO:0003700sequence-specific DNA binding transcription factor activity IEA--
GO:0043565sequence-specific DNA binding IEA--
     
RAX2 for ontologies           About GeneDecksing


Phenotypes:
     1 GenomeRNAi human phenotype for RAX2:
 Increased gamma-H2AX phosphory 

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RAX2
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RAX2

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RAX2
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RAX2

miRNA
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Inhib. RNA
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Predesigned siRNA for gene silencing in human, mouse, rat RAX2

Gene Editing
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Clone
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OriGene clones in human, mouse for RAX2 (see all 4)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: RAX2 (NM_032753)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for RAX2
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAX2

Cell Line
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In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAX2


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
RAX2_HUMAN, Q96IS3: Nucleus (By similarity)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
nucleus3

Gene Ontology (GO): 1 cellular component term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IEA--

RAX2 for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RAX2
Interactions:

    Search GeneGlobe Interaction Network for RAX2

1 Interacting protein for RAX2 (Q96IS33) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
CRXO431863I2D: score=1 
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Gene Ontology (GO): 4 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006351transcription, DNA-templated IEA--
GO:0006355regulation of transcription, DNA-templated ----
GO:0007601visual perception IEA--
GO:0050896response to stimulus IEA--

RAX2 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for RAX2



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for RAX2 gene: 
NM_032753.3  

Unigene Cluster for RAX2:

Retina and anterior neural fold homeobox 2
Hs.532691  [show with all ESTs]
Unigene Representative Sequence: BC018709
2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000555978 ENST00000555633(uc002lys.3 uc010dtp.2 uc002lyr.3)

miRNA
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Search for qRT-PCR Assays for microRNAs that regulate RAX2
SwitchGear 3'UTR luciferase reporter plasmidRAX2 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for RAX2
Predesigned siRNA for gene silencing in human, mouse, rat RAX2
Clone
Products:
     
OriGene clones in human, mouse for RAX2 (see all 4)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: RAX2 (NM_032753)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for RAX2
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAX2
Primer
Products:
    
OriGene qPCR primer pairs and template standards for RAX2
OriGene qSTAR qPCR primer pairs in human, mouse for RAX2
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat RAX2
  QuantiTect SYBR Green Assays in human, mouse, rat RAX2
  QuantiFast Probe-based Assays in human, mouse, rat RAX2

Additional mRNA sequence: 

AY211277.1 BC018709.1 BC032512.1 

3 DOTS entries:

DT.97792768  DT.101960631  DT.91986703 

Selected AceView cDNA sequences (see all 37):

BE253378 BQ639859 BM683813 BC007284 BQ638250 BU167304 BQ638529 BE252433 
BM666594 BG396814 BU726980 BM688188 BC032512 BQ639073 BQ639716 BQ636803 
BQ639124 BQ637215 AY211277 NM_032753 BC018709 BE251574 BE251920 BM479851 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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RAX2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GGATGGGACA
RAX2 Expression
About this image

RAX2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

RAX2 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.532691
    Custom PCR Arrays for RAX2
Primer
Products:
OriGene qPCR primer pairs and template standards for RAX2
OriGene qSTAR qPCR primer pairs in human, mouse for RAX2
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat RAX2
QuantiTect SYBR Green Assays in human, mouse, rat RAX2
QuantiFast Probe-based Assays in human, mouse, rat RAX2
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAX2

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for RAX2 gene from Selected species (see all 11)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
dog
(Canis familiaris)
Mammalia RAX21 retina and anterior neural fold homeobox 2 88.22(n)
92.39(a)
  612000  XM_005633071.1  XP_005633128.1 
chicken
(Gallus gallus)
Aves RAX16
Gallus gallus retina and anterior neural fold home...
29(a)
1 → many
Z(918774-923060)
lizard
(Anolis carolinensis)
Reptilia --
--
29(a)
1 → many
GL343335.1(1042112-1059344)
zebrafish
(Danio rerio)
Actinopterygii rx36
retinal homeobox gene 3
33(a)
1 → many
21(9291473-9294542) ENSDARG00000052893
fruit fly
(Drosophila melanogaster)
Insecta hbn6
homeobrain
15(a)
many ↔ many
2R(16842169-16848414)
worm
(Caenorhabditis elegans)
Secernentea ceh-86
Protein CEH-8 (ceh-8) mRNA, complete cds
23(a)
1 → many
I(8245722-8250896) WBGene00000433


ENSEMBL Gene Tree for RAX2 (if available)
TreeFam Gene Tree for RAX2 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for RAX2 gene
ALX12  PHOX2B2  ARX2  RAX2  DRGX2  SHOX22  PRRX12  PHOX2A2  
ALX42  ISX2  ALX32  SHOX2  OTP2  PRRX22  
Selected SIMAP similar genes for RAX2 using alignment to 1 protein entry:     RAX2_HUMAN(see all similar genes):
VSX1    ALX1    PITX2    GSC2    UNCX    OTX1
PITX1    ALX4    ARX    PRRX1    PAX4    PAX6
SHOX2    ISX    PRRX2    BARHL1    PHOX2B    DRGX

RAX2 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for RAX2 (see all 153)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 19 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
VAR_0319074
Macular degeneration, age-related, 6 (ARMD6)4--see VAR_0319072 R Q mis40--------
VAR_0319084
Cone-rod dystrophy 11 (CORD11)4--see VAR_0319082 G R mis40--------
rs1219082801,2
Cpathogenic13695269(-) GGAGCA/GGCTGG 2 Q R mis10--------
rs1134549111,2
C--3537797(+) AAAAAA/CAAACA 1 -- us2k10--------
rs1823107651,2
--3537800(+) AAAAAA/CCAAAA 1 -- us2k10--------
rs598081941,2
C,F--3693012(+) CCGGCG/AGCCTC 1 -- ds50015Minor allele frequency- A:0.22WA NA CSA 244
rs1154162971,2
C,F--3693021(+) TCCCTG/AGGCAG 1 -- ds50011Minor allele frequency- A:0.09WA 118
rs794970961,2
F--3693043(+) AGCGCG/ACCTTC 1 -- ds50012Minor allele frequency- A:0.05CSA WA 120
rs1895633801,2
--3693077(+) CCAGCC/TGTTCC 1 -- ds50010--------
rs72569791,2
C,F--3693133(+) TATAAC/GAGCCA 1 -- ds50017Minor allele frequency- G:0.44NA WA EA 366

HapMap Linkage Disequilibrium report for RAX2 (3769087 - 3772233 bp)

Structural Variations
     Database of Genomic Variants (DGV) 10 variations for RAX2:    About this table    
Variant IDTypeSubtypePubMed ID
nsv509718CNV Insertion20534489
dgv3651n71CNV Loss21882294
nsv910722CNV Loss21882294
nsv910775CNV Loss21882294
dgv3663n71CNV Loss21882294
nsv470114CNV Loss18288195
nsv910777CNV Loss21882294
nsv910770CNV Loss21882294
dgv3660n71CNV Loss21882294
dgv3662n71CNV Loss21882294

Human Gene Mutation Database (HGMD): RAX2
Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing RAX2
DNA2.0 Custom Variant and Variant Library Synthesis for RAX2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 610362   
OMIM disorders: 613757  610381  
UniProtKB/Swiss-Prot: RAX2_HUMAN, Q96IS3
  • Macular degeneration, age-related, 6 (ARMD6) [MIM:613757]: A form of age-related macular degeneration, a
    multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most
    patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid
    that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch
    membrane. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry
  • Cone-rod dystrophy 11 (CORD11) [MIM:610381]: An inherited retinal dystrophy characterized by retinal
    pigment deposits visible on fundus examination, predominantly in the macular region, and initial loss of cone
    photoreceptors followed by rod degeneration. This leads to decreased visual acuity and sensitivity in the central
    visual field, followed by loss of peripheral vision. Severe loss of vision occurs earlier than in retinitis
    pigmentosa. Note=The disease is caused by mutations affecting the gene represented in this entry

  • 12 diseases for RAX2:    
    About MalaCards
    cone-rod dystrophy 11    age-related macular degeneration 6    age related macular degeneration    cone-rod dystrophy 2
    cone-rod dystrophy    retinitis    night blindness    blindness
    hepatitis b    multiple myeloma    hepatitis    myeloma


    RAX2 for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: RAX2 (1 document)

    Export disorders for RAX2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RAX2 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with RAX2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. QRX, a novel homeobox gene, modulates photoreceptor gene expression. (PubMed id 15028672)1, 2 Wang Q.-L.... Zack D.J. (Hum. Mol. Genet. 2004)
    2. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (Genes Immun. 2010)
    3. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (Nature 2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 84839 HGNC: 18286 AceView: MGC15631 Ensembl:ENSG00000173976 euGenes: HUgn84839
    ECgene: RAX2 H-InvDB: RAX2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RAX2 Pharmacogenomics, SNPs, Pathways
    GeneReviewshttp://www.ncbi.nlm.nih.gov/books/NBK1116/?term=RAX2[genesymbol]

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RAX2 gene:
    Search GeneIP for patents involving RAX2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for RAX2  
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     Custom PCR Arrays for RAX2 Search Chromatin IP Primers for RAX2
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     Novus Tissue Slides
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     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RAX2
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