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Aliases for RAVER2 Gene

Aliases for RAVER2 Gene

  • Ribonucleoprotein, PTB-Binding 2 2 3
  • KIAA1579 4 6
  • Protein Raver-2 4

External Ids for RAVER2 Gene

Previous GeneCards Identifiers for RAVER2 Gene

  • GC01P064916
  • GC01P065210
  • GC01P063319

Summaries for RAVER2 Gene

GeneCards Summary for RAVER2 Gene

RAVER2 (Ribonucleoprotein, PTB-Binding 2) is a Protein Coding gene. GO annotations related to this gene include RNA binding and nucleotide binding. An important paralog of this gene is RAVER1.

UniProtKB/Swiss-Prot for RAVER2 Gene

  • May bind single-stranded nucleic acids.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RAVER2 Gene

Genomics for RAVER2 Gene

Regulatory Elements for RAVER2 Gene

Genomic Location for RAVER2 Gene

64,745,095 bp from pter
64,833,232 bp from pter
88,138 bases
Plus strand

Genomic View for RAVER2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RAVER2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RAVER2 Gene

Proteins for RAVER2 Gene

  • Protein details for RAVER2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ribonucleoprotein PTB-binding 2
    Protein Accession:
    Secondary Accessions:
    • Q6P141
    • Q9NPV7

    Protein attributes for RAVER2 Gene

    691 amino acids
    Molecular mass:
    74339 Da
    Quaternary structure:
    • Interacts with PTBP1 and RAVER1.
    • Sequence=BAB13405.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for RAVER2 Gene

    Alternative splice isoforms for RAVER2 Gene


neXtProt entry for RAVER2 Gene

Proteomics data for RAVER2 Gene at MOPED

Post-translational modifications for RAVER2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RAVER2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RAVER2 Gene

Domains for RAVER2 Gene

Gene Families for RAVER2 Gene

Suggested Antigen Peptide Sequences for RAVER2 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 3 RRM (RNA recognition motif) domains.
  • Contains 3 RRM (RNA recognition motif) domains.
genes like me logo Genes that share domains with RAVER2: view

Function for RAVER2 Gene

Molecular function for RAVER2 Gene

UniProtKB/Swiss-Prot Function:
May bind single-stranded nucleic acids.

Gene Ontology (GO) - Molecular Function for RAVER2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0003676 nucleic acid binding --
GO:0005515 protein binding --
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with RAVER2: view

Animal Model Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RAVER2

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for RAVER2 Gene

Localization for RAVER2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RAVER2 Gene

Nucleus. Cytoplasm. Note=May shuttle between the nucleus and the cytoplasm. {ECO:0000250}.

Subcellular locations from

Jensen Localization Image for RAVER2 Gene COMPARTMENTS Subcellular localization image for RAVER2 gene
Compartment Confidence
nucleus 3
cytosol 1

Gene Ontology (GO) - Cellular Components for RAVER2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with RAVER2: view

Pathways for RAVER2 Gene

SuperPathways for RAVER2 Gene

No Data Available

Interacting Proteins for RAVER2 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
Selected Interacting proteins: ENSP00000360112 Q9HCJ3-RAVR2_HUMAN for RAVER2 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for RAVER2 Gene


No data available for Pathways by source for RAVER2 Gene

Transcripts for RAVER2 Gene

Unigene Clusters for RAVER2 Gene

Ribonucleoprotein, PTB-binding 2:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RAVER2

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RAVER2 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b · 11c ^ 12a · 12b
SP1: - - -
SP2: - -
SP3: - - -

Relevant External Links for RAVER2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RAVER2 Gene

mRNA expression in normal human tissues for RAVER2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for RAVER2 Gene

This gene is overexpressed in Adipocyte (24.0), Pancreas (14.9), Placenta (14.2), and Islet of Langerhans (13.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for RAVER2 Gene

SOURCE GeneReport for Unigene cluster for RAVER2 Gene Hs.591443

genes like me logo Genes that share expressions with RAVER2: view

Expression partners for RAVER2 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RAVER2 Gene

Orthologs for RAVER2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RAVER2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia RAVER2 35
  • 91.32 (n)
  • 90.91 (a)
  • 85 (a)
(Canis familiaris)
Mammalia RAVER2 35
  • 91.36 (n)
  • 92.59 (a)
  • 91 (a)
(Mus musculus)
Mammalia Raver2 35
  • 81.25 (n)
  • 82.66 (a)
Raver2 16
Raver2 36
  • 78 (a)
(Pan troglodytes)
Mammalia RAVER2 35
  • 99.51 (n)
  • 99.12 (a)
  • 99 (a)
(Rattus norvegicus)
Mammalia Raver2 35
  • 81.25 (n)
  • 82.03 (a)
(Monodelphis domestica)
Mammalia RAVER2 36
  • 70 (a)
(Ornithorhynchus anatinus)
Mammalia RAVER2 36
  • 68 (a)
(Gallus gallus)
Aves RAVER2 35
  • 71.76 (n)
  • 69.47 (a)
  • 63 (a)
(Anolis carolinensis)
Reptilia RAVER2 36
  • 56 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia raver2 35
  • 64.88 (n)
  • 59.88 (a)
(Danio rerio)
Actinopterygii raver2 35
  • 57.13 (n)
  • 55.8 (a)
raver2 36
  • 37 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2565 36
  • 32 (a)
Species with no ortholog for RAVER2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RAVER2 Gene

Gene Tree for RAVER2 (if available)
Gene Tree for RAVER2 (if available)

Paralogs for RAVER2 Gene

Paralogs for RAVER2 Gene

(1) SIMAP similar genes for RAVER2 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with RAVER2: view

Variants for RAVER2 Gene

Sequence variations from dbSNP and Humsavar for RAVER2 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs78549142 -- 64,748,155(+) AAAAA(G/T)TGAAC intron-variant
rs78768555 -- 64,797,415(+) TGTTA(C/T)AAACT intron-variant
rs78789586 -- 64,761,949(+) CTACC(A/C)AAAAA intron-variant
rs78807752 -- 64,794,720(+) TTGTA(A/G)GAGTG intron-variant
rs78846439 -- 64,763,043(+) AGTGG(C/G)TCACG intron-variant

Relevant External Links for RAVER2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for RAVER2 Gene

Disorders for RAVER2 Gene

Relevant External Links for RAVER2

Human Genome Epidemiology (HuGE) Navigator

No disorders were found for RAVER2 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for RAVER2 Gene

Publications for RAVER2 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Raver2, a new member of the hnRNP family. (PMID: 16051233) Kleinhenz B. … Illenberger S. (FEBS Lett. 2005) 2 3
  3. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10997877) Nagase T. … Ohara O. (DNA Res. 2000) 3 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for RAVER2 Gene

Sources for RAVER2 Gene

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