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RAVER1 Gene

protein-coding   GIFtS: 49
GCID: GC19M010426

Ribonucleoprotein, PTB-Binding 1

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ribonucleoprotein, PTB-Binding 11 2
Protein Raver-12 3
KIAA19783 5
Ribonucleoprotein PTB-Binding 12

External Ids:    HGNC: 302961   Entrez Gene: 1259502   Ensembl: ENSG000001618477   OMIM: 6099505   UniProtKB: Q8IY673   

Export aliases for RAVER1 gene to outside databases

Previous GC identifers: GC19U990309 GC19M010649 GC19M010272 GC19M010287 GC19M010007


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RAVER1 Gene:
RAVER1 (ribonucleoprotein, PTB-binding 1) is a protein-coding gene. GO annotations related to this gene include RNA binding and nucleotide binding. An important paralog of this gene is ENSG00000267303.

UniProtKB/Swiss-Prot: RAVR1_HUMAN, Q8IY67
Function: Cooperates with PTBP1 to modulate regulated alternative splicing events. Promotes exon skipping.
Cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1
pre-mRNA (By similarity)

Gene Wiki entry for RAVER1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the RAVER1 gene promoter:
         HEN1   Sp1   Bach2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRAVER1 promoter sequence
   Search Chromatin IP Primers for RAVER1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RAVER1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.2   Ensembl cytogenetic band:  19p13.2   HGNC cytogenetic band: 19p13.2

RAVER1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAVER1 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M010426:  view genomic region     (about GC identifiers)

Start:
10,426,888 bp from pter      End:
10,444,316 bp from pter
Size:
17,429 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: RAVR1_HUMAN, Q8IY67 (See protein sequence)
Recommended Name: Ribonucleoprotein PTB-binding 1  
Size: 606 amino acids; 63877 Da
Subunit: Interacts with PTBP1, RAVER2, VCL and ACTN1. Part of a complex containing RAVER1, VCL and ACTN1 (By
similarity)
Sequence caution: Sequence=AAH37565.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact;
Sequence=BAB85564.1; Type=Miscellaneous discrepancy; Note=Intron retention;
4 PDB 3D structures from and Proteopedia for RAVER1:
3H2U (3D)        3H2V (3D)        3SMZ (3D)        3VF0 (3D)    
Secondary accessions: A6NMU4 Q8IY60 Q8TF24
Alternative splicing: 3 isoforms:  Q8IY67-1   Q8IY67-2   Q8IY67-3   (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for RAVER1: NX_Q8IY67

Explore proteomics data for RAVER1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RAVER1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_597709.2  
    ENSEMBL proteins: 
     ENSP00000293677   ENSP00000465532   ENSP00000468375   ENSP00000465753  

    RAVER1 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for RAVER1

     
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    antibodies-online proteins for RAVER1 (2 products) 

     
    antibodies-online peptides for RAVER1

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    antibodies-online antibodies for RAVER1 (19 products) 

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    Cloud-Clone Corp. CLIAs for RAVER1
    Search eBioscience for ELISAs for RAVER1 
    antibodies-online kits for RAVER1 (6 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RBM: RNA binding motif (RRM) containing

    2 InterPro protein domains:
     IPR012677 Nucleotide-bd_a/b_plait
     IPR000504 RRM_dom

    Graphical View of Domain Structure for InterPro Entry Q8IY67

    ProtoNet protein and cluster: Q8IY67

    1 Blocks protein domain: IPB000504 RNA-binding region RNP-1 (RNA recognition motif)

    UniProtKB/Swiss-Prot: RAVR1_HUMAN, Q8IY67
    Similarity: Contains 3 RRM (RNA recognition motif) domains


    Find genes that share domains with RAVER1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RAVR1_HUMAN, Q8IY67
    Function: Cooperates with PTBP1 to modulate regulated alternative splicing events. Promotes exon skipping.
    Cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1
    pre-mRNA (By similarity)

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0003676nucleic acid binding ----
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with RAVER1           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for RAVER1:
     Increased gamma-H2AX phosphory 

         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Raver1):
     cellular  nervous system 

    Find genes that share phenotypes with RAVER1           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for RAVER1

    miRNA
    Products:
        
    miRTarBase miRNAs that target RAVER1:
    hsa-let-7a-5p (MIRT052550), hsa-mir-124-3p (MIRT022658), hsa-mir-361-5p (MIRT044108), hsa-mir-92a-3p (MIRT049468), hsa-mir-193b-3p (MIRT016348)

    Block miRNA regulation of human, mouse, rat RAVER1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RAVER1 (see all 19):
    hsa-miR-4291 hsa-miR-3910 hsa-miR-520d-5p hsa-miR-4267 hsa-miR-124 hsa-miR-133a hsa-miR-506 hsa-miR-1252
    SwitchGear 3'UTR luciferase reporter plasmidRAVER1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat RAVER1

    Gene Editing
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    Browse Sino Biological Human cDNA Clones
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAVER1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RAVR1_HUMAN, Q8IY67: Nucleus (By similarity). Cytoplasm (By similarity). Note=Nuclear, in perinucleolar
    structures. Shuttles between nucleus and cytoplasm. Cytoplasm, at focal contacts and cell-cell contacts.
    Associated with myotubes during muscle differentiation (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytoskeleton1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--

    Find genes that share ontologies with RAVER1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RAVER1
    Interactions:

        GeneGlobe Interaction Network for RAVER1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 12)

    Selected Interacting proteins for RAVER1 (Q8IY672, 3 ENSP000002936774) via UniProtKB, MINT, STRING, and/or I2D (see all 563)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PTBP1P265992, 3, ENSP000003494284MINT-7947479 I2D: score=2 STRING: ENSP00000349428
    PTBP3O957582, 3, ENSP000003633734MINT-7947479 I2D: score=1 STRING: ENSP00000363373
    ACTN4O437073, ENSP000002526994I2D: score=1 STRING: ENSP00000252699
    TERF2Q155543, ENSP000002549424I2D: score=1 STRING: ENSP00000254942
    TOB1P506163, ENSP000002689574I2D: score=1 STRING: ENSP00000268957
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RAVER1 (RAVR1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RAVER1 gene: 
    NM_133452.2  

    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000293677(uc002mnz.3 uc002moa.3) ENST00000592208 ENST00000585935
    ENST00000593136 ENST00000591969
    miRNA
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    Block miRNA regulation of human, mouse, rat RAVER1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RAVER1 (see all 19):
    hsa-miR-4291 hsa-miR-3910 hsa-miR-520d-5p hsa-miR-4267 hsa-miR-124 hsa-miR-133a hsa-miR-506 hsa-miR-1252
    SwitchGear 3'UTR luciferase reporter plasmidRAVER1 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for RAVER1
    Predesigned siRNA for gene silencing in human, mouse, rat RAVER1
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    OriGene clones in human, mouse for RAVER1 (see all 7)
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RAVER1 (NM_133452)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RAVER1
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat RAVER1
    Primer
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    OriGene qPCR primer pairs and template standards for RAVER1
    OriGene qSTAR qPCR primer pairs in human, mouse for RAVER1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RAVER1
      QuantiTect SYBR Green Assays in human, mouse, rat RAVER1
      QuantiFast Probe-based Assays in human, mouse, rat RAVER1

    Selected AceView cDNA sequences (see all 529):

    AW631239 BQ109567 BM460975 BM680875 BQ011343 AW237209 CR590285 BQ062308 
    BM709068 BM713265 AI498122 CA391180 BX104157 BX100113 BM738616 BC037428 
    BI333296 BQ901061 BE883887 BG257988 N95446 BM726266 BF724596 BQ430683 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for RAVER1    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12
    SP1:                                                                                                
    SP2:                                                                                                
    SP3:                          -                                                                     
    SP4:                                                                                                
    SP5:                    -                                                                           


    ECgene alternative splicing isoforms for RAVER1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RAVER1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    RAVER1 Expression
    About this image


    RAVER1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Ovarian Mesenchymal Stroma Cells Ovary Interstitium
             Oviduct
     
     Pancreas (Endocrine System)
             Islets of Langerhans
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Eye (Sensory Organs)
             Retina
    RAVER1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RAVER1 Protein Expression
        Custom PCR Arrays for RAVER1
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for RAVER1 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Raver11 , 5 ribonucleoprotein, PTB-binding 11, 5 84.44(n)1
    89.04(a)1
      9 (7.71 cM)5
    717661  NM_027911.31  NP_082187.11 
     210741685 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    58(a)
    1 → many
    2(27775566-27836596)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.308982 Xenopus laevis transcribed sequences 75.56(n)    CB208172.1 
    zebrafish
    (Danio rerio)
    Actinopterygii raver16
    ribonucleoprotein, PTB-binding 1
    49(a)
    1 → many
    3(46597752-46625119) ENSDARG00000052617


    ENSEMBL Gene Tree for RAVER1 (if available)
    TreeFam Gene Tree for RAVER1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RAVER1 gene
    ENSG000002673032  RAVER22  
    1 SIMAP similar gene for RAVER1 using alignment to 5 protein entries:     RAVR1_HUMAN (see all proteins):
    RAVER2

    Find genes that share paralogs with RAVER1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RAVER1 (see all 386)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs774389951,2
    C,F--10428788(+) ACCAAC/ACCCTG 1 -- int12Minor allele frequency- A:0.09WA NA 238
    rs124591441,2
    C,F,A,H--10428790(+) CAACCC/TCTGCC 1 -- int118Minor allele frequency- T:0.19NS EA NA WA 2132
    rs1877842211,2
    --10428803(+) CACCCC/GAGCTT 1 -- int10--------
    rs1475894401,2
    C--10428992(+) GGGGG-/CC/CCC
            
    CCCCC
    3 P A G fra1 cds10--------
    rs2814271,2
    C,F,H--10429120(+) CCCTCC/TGCCTC 1 -- int1 trp311Minor allele frequency- T:0.25NA WA CSA EA 257
    rs1929000021,2
    --10429184(+) CATGCA/GCCACC 1 -- int10--------
    rs1845876911,2
    --10429225(+) GAGACA/GGGGTT 1 -- int10--------
    rs1898574851,2
    C--10429253(+) CTGGTC/TTCACA 1 -- int10--------
    rs1454924381,2
    --10429402(+) ACCCGC/TCTCCT 1 -- int10--------
    rs1382010401,2
    --10429443(+) CCGCAC/TGAATG 1 -- int10--------

    HapMap Linkage Disequilibrium report for RAVER1 (10426888 - 10444316 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for RAVER1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv911040CNV Loss21882294
    nsv911030CNV Loss21882294
    nsv911029CNV Loss21882294
    dgv3726n71CNV Loss21882294
    dgv3725n71CNV Loss21882294
    nsv470124CNV Gain18288195

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609950    OMIM disorders: --


    Find genes that share disorders with RAVER1           About GenesLikeMe

    Genetic Association Database (GAD): RAVER1
    Human Genome Epidemiology (HuGE) Navigator: RAVER1 (7 documents)

    Export disorders for RAVER1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RAVER1 gene, integrated from 10 sources (see all 38):
    (articles sorted by number of sources associating them with RAVER1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. (PubMed id 11853319)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 2001)
    2. Risk of meningioma and common variation in genes related to innate immunity. (PubMed id 20406964)1, 4 Rajaraman P....Inskip P.D. (amp 2010)
    3. Polymorphisms in innate immunity genes and risk of childhood leukemia. (PubMed id 20438785)1, 4 Han S....Kang D. (Hum. Immunol. 2010)
    4. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    5. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (Nat. Biotechnol. 2006)
    6. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Raver1, a dual compartment protein, is a ligand for PTB/hnRNPI and microfilament attachment proteins. (PubMed id 11724819)1, 3 HA1ttelmaier S....Jockusch B.M. (J. Cell Biol. 2001)
    9. RAVER1 is a coactivator of MDA5-mediated cellular antiviral response. (PubMed id 23390309)1 Chen H....Shu H.B. (J Mol Cell Biol 2013)
    10. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 125950 HGNC: 30296 AceView: ICAM3andMGC19604andRAVER1 Ensembl:ENSG00000161847 euGenes: HUgn125950
    ECgene: RAVER1 H-InvDB: RAVER1

    (According to HUGE)
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    HUGE: KIAA1978

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RAVER1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RAVER1 gene:
    Search GeneIP for patents involving RAVER1

    GeneCards and IP:
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