Free for academic non-profit institutions. Other users need a Commercial license

Aliases for RASSF9 Gene

Aliases for RASSF9 Gene

  • Ras Association (RalGDS/AF-6) Domain Family (N-Terminal) Member 9 2 3
  • PAMCI 3 4 6
  • PCIP1 3 4 6
  • Peptidylglycine Alpha-Amidating Monooxygenase COOH-Terminal Interactor 2 4
  • PAM COOH-Terminal Interactor Protein 1 3 4
  • P-CIP1 3 4
  • Peptidylglycine Alpha-Amidating Monooxygenase COOH-Terminal Interactor Protein-1 3
  • Ras Association Domain-Containing Protein 9 3

External Ids for RASSF9 Gene

Previous HGNC Symbols for RASSF9 Gene

  • PAMCI

Previous GeneCards Identifiers for RASSF9 Gene

  • GC12M084722
  • GC12M086198
  • GC12M083254

Summaries for RASSF9 Gene

Entrez Gene Summary for RASSF9 Gene

  • The protein encoded by this gene localizes to perinuclear endosomes. This protein associates with peptidylglycine alpha-amidating monooxygenase, and may be involved with the trafficking of this enzyme through secretory or endosomal pathways. [provided by RefSeq, Jul 2008]

GeneCards Summary for RASSF9 Gene

RASSF9 (Ras Association (RalGDS/AF-6) Domain Family (N-Terminal) Member 9) is a Protein Coding gene. GO annotations related to this gene include transporter activity.

UniProtKB/Swiss-Prot for RASSF9 Gene

  • May play a role in regulating vesicuar trafficking in cells.

Gene Wiki entry for RASSF9 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RASSF9 Gene

Genomics for RASSF9 Gene

Regulatory Elements for RASSF9 Gene

Genomic Location for RASSF9 Gene

Start:
85,800,697 bp from pter
End:
85,836,570 bp from pter
Size:
35,874 bases
Orientation:
Minus strand

Genomic View for RASSF9 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RASSF9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RASSF9 Gene

Proteins for RASSF9 Gene

  • Protein details for RASSF9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O75901-RASF9_HUMAN
    Recommended name:
    Ras association domain-containing protein 9
    Protein Accession:
    O75901
    Secondary Accessions:
    • B3KMQ4
    • Q8N5U8

    Protein attributes for RASSF9 Gene

    Size:
    435 amino acids
    Molecular mass:
    50021 Da
    Quaternary structure:
    • Interacts with PAM.

neXtProt entry for RASSF9 Gene

Proteomics data for RASSF9 Gene at MOPED

Post-translational modifications for RASSF9 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RASSF9 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for RASSF9 Gene

Domains for RASSF9 Gene

Protein Domains for RASSF9 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for RASSF9 Gene

Graphical View of Domain Structure for InterPro Entry

O75901

UniProtKB/Swiss-Prot:

RASF9_HUMAN :
  • O75901
Domain:
  • Contains 1 Ras-associating domain.
genes like me logo Genes that share domains with RASSF9: view

No data available for Gene Families for RASSF9 Gene

Function for RASSF9 Gene

Molecular function for RASSF9 Gene

UniProtKB/Swiss-Prot Function:
May play a role in regulating vesicuar trafficking in cells.

Gene Ontology (GO) - Molecular Function for RASSF9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005215 transporter activity NAS 9837933
GO:0005515 protein binding IPI 9837933
genes like me logo Genes that share ontologies with RASSF9: view

Phenotypes for RASSF9 Gene

GenomeRNAi human phenotypes for RASSF9:
genes like me logo Genes that share phenotypes with RASSF9: view

Animal Model Products

CRISPR Products

miRNA for RASSF9 Gene

miRTarBase miRNAs that target RASSF9

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RASSF9

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for RASSF9 Gene

Localization for RASSF9 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RASSF9 Gene

Endosome. Note=Accumulates on perinuclear endosomes. {ECO:0000250}.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RASSF9 Gene COMPARTMENTS Subcellular localization image for RASSF9 gene
Compartment Confidence
cytosol 5
endosome 5
golgi apparatus 5
nucleus 3
mitochondrion 1

Gene Ontology (GO) - Cellular Components for RASSF9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005768 endosome IDA 9837933
GO:0005829 cytosol IDA 9837933
GO:0012510 trans-Golgi network transport vesicle membrane IDA 9837933
GO:0070062 extracellular exosome IDA 18570454
genes like me logo Genes that share ontologies with RASSF9: view

Pathways for RASSF9 Gene

SuperPathways for RASSF9 Gene

No Data Available

Gene Ontology (GO) - Biological Process for RASSF9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006605 protein targeting NAS 9837933
GO:0007165 signal transduction IEA --
GO:0016197 endosomal transport NAS 9837933
genes like me logo Genes that share ontologies with RASSF9: view

No data available for Pathways by source for RASSF9 Gene

Transcripts for RASSF9 Gene

mRNA/cDNA for RASSF9 Gene

(17) Selected AceView cDNA sequences:
(3) Additional mRNA sequences :
(2) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RASSF9 Gene

Ras association (RalGDS/AF-6) domain family (N-terminal) member 9:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RASSF9

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RASSF9 Gene

No ASD Table

Relevant External Links for RASSF9 Gene

GeneLoc Exon Structure for
RASSF9
ECgene alternative splicing isoforms for
RASSF9

Expression for RASSF9 Gene

mRNA expression in normal human tissues for RASSF9 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for RASSF9 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for RASSF9 Gene

SOURCE GeneReport for Unigene cluster for RASSF9 Gene Hs.527881

genes like me logo Genes that share expressions with RASSF9: view

Expression partners for RASSF9 Gene

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RASSF9 Gene

Orthologs for RASSF9 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RASSF9 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia RASSF9 35
  • 91.8 (n)
  • 92.18 (a)
RASSF9 36
  • 92 (a)
OneToOne
dog
(Canis familiaris)
Mammalia RASSF9 35
  • 91.53 (n)
  • 91.21 (a)
RASSF9 36
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Rassf9 35
  • 82.76 (n)
  • 85.29 (a)
Rassf9 16
Rassf9 36
  • 85 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia RASSF9 35
  • 99.92 (n)
  • 99.77 (a)
RASSF9 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Rassf9 35
  • 82.84 (n)
  • 85.29 (a)
oppossum
(Monodelphis domestica)
Mammalia RASSF9 36
  • 82 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia RASSF9 36
  • 77 (a)
OneToOne
chicken
(Gallus gallus)
Aves RASSF9 35
  • 72.26 (n)
  • 69.89 (a)
RASSF9 36
  • 69 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia RASSF9 36
  • 61 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia rassf9 35
  • 59.29 (n)
  • 50.25 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC100150148 35
  • 55.7 (n)
  • 46.48 (a)
rassf9 36
  • 41 (a)
OneToOne
Species with no ortholog for RASSF9:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RASSF9 Gene

ENSEMBL:
Gene Tree for RASSF9 (if available)
TreeFam:
Gene Tree for RASSF9 (if available)

Paralogs for RASSF9 Gene

Pseudogenes.org Pseudogenes for RASSF9 Gene

genes like me logo Genes that share paralogs with RASSF9: view

No data available for Paralogs for RASSF9 Gene

Variants for RASSF9 Gene

Sequence variations from dbSNP and Humsavar for RASSF9 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs1135367 -- 85,805,895(-) AGAAG(C/T)TTGTC reference, missense
rs1349060 -- 85,835,944(+) TCACT(C/G)CCATC intron-variant
rs1349061 -- 85,836,065(+) AAACA(C/T)ATACT intron-variant
rs1448095 -- 85,809,879(+) GTTAC(A/C)TACTA intron-variant
rs1448096 -- 85,830,845(+) GTGTA(A/G)TACTA intron-variant

Relevant External Links for RASSF9 Gene

HapMap Linkage Disequilibrium report
RASSF9

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for RASSF9 Gene

Disorders for RASSF9 Gene

No disorders were found for RASSF9 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for RASSF9 Gene

Publications for RASSF9 Gene

  1. P-CIP1, a novel protein that interacts with the cytosolic domain of peptidylglycine alpha-amidating monooxygenase, is associated with endosomes. (PMID: 9837933) Chen L. … Milgram S.L. (J. Biol. Chem. 1998) 2 3 4 23
  2. RASSF7 is a member of a new family of RAS association domain- containing proteins and is required for completing mitosis. (PMID: 18272789) Sherwood V. … Chalmers A.D. (Mol. Biol. Cell 2008) 2 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry. (PMID: 18570454) Kang D. … Moon M.H. (J. Proteome Res. 2008) 3

Products for RASSF9 Gene

Sources for RASSF9 Gene

Back to Top

Content