Aliases for RASSF8 Gene
External Ids for RASSF8 Gene
Previous Symbols for RASSF8 Gene
This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
GeneCards Summary for RASSF8 Gene
RASSF8 (Ras Association (RalGDS/AF-6) Domain Family (N-Terminal) Member 8) is a Protein Coding gene. Diseases associated with RASSF8 include synpolydactyly. An important paralog of this gene is RASSF7.