Aliases for RASSF7 Gene
External Ids for RASSF7 Gene
Previous HGNC Symbols for RASSF7 Gene
Previous GeneCards Identifiers for RASSF7 Gene
GeneCards Summary for RASSF7 Gene
RASSF7 (Ras Association (RalGDS/AF-6) Domain Family (N-Terminal) Member 7) is a Protein Coding gene. Among its related pathways are Regulation of actin cytoskeleton. An important paralog of this gene is RASSF8.
UniProtKB/Swiss-Prot for RASSF7 Gene
Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization.