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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RASSF4 Gene

protein-coding   GIFtS: 55
GCID: GC10P045454

Ras Association (RalGDS/AF-6) Domain Family Member 4

Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ras Association (RalGDS/AF-6) Domain Family Member 41 2
AD0372
Ras Association (RalGDS/AF-6) Domain Family 42
Ras Association Domain Family 42
Ras Association Domain-Containing Protein 42
Tumor Suppressor RASSF42

External Ids:    HGNC: 207931   Entrez Gene: 839372   Ensembl: ENSG000001075517   OMIM: 6105595   UniProtKB: Q9H2L53   

Export aliases for RASSF4 gene to outside databases

Previous GC identifers: GC10P045230 GC10P044739 GC10P044775 GC10P041979


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RASSF4 Gene:
The function of this gene has not yet been determined but may involve a role in tumor suppression. Alternative
splicing of this gene results in several transcript variants; however, most of the variants have not been fully
described. (provided by RefSeq, Jul 2008)

GeneCards Summary for RASSF4 Gene: 
RASSF4 (Ras association (RalGDS/AF-6) domain family member 4) is a protein-coding gene. Diseases associated with RASSF4 include macrocephaly, alopecia, cutis laxa, and scoliosis, and nasopharyngitis. GO annotations related to this gene include protein binding. An important paralog of this gene is RASSF2.

UniProtKB/Swiss-Prot: RASF4_HUMAN, Q9H2L5
Function: Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle
arrest




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NT_033985.7  NC_018921.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RASSF4 gene promoter:
         SRF   RFX1   Pax-5   SRF (504 AA)   Bach2   HNF-1A   AREB6   SRY   HNF-1   ZID   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRASSF4 promoter sequence
   Search SABiosciences Chromatin IP Primers for RASSF4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RASSF4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q11.21   Ensembl cytogenetic band:  10q11.21   HGNC cytogenetic band: 10q11.1

RASSF4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RASSF4 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P045454:  view genomic region     (about GC identifiers)

Start:
45,454,855 bp from pter      End:
45,490,172 bp from pter
Size:
35,318 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RASF4_HUMAN, Q9H2L5 (See protein sequence)
Recommended Name: Ras association domain-containing protein 4  
Size: 321 amino acids; 36748 Da
Subunit: Interacts directly with activated KRAS in a GTP-dependent manner
Secondary accessions: Q86WH5 Q86WH6 Q86WH7 Q8N5A9 Q8TCK6
Alternative splicing: 4 isoforms:  Q9H2L5-1   Q9H2L5-2   Q9H2L5-3   Q9H2L5-4   

Explore the universe of human proteins at neXtProt for RASSF4: NX_Q9H2L5

Explore proteomics data for RASSF4 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9H2L5

  • RASSF4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RASSF4 Protein Expression
    REFSEQ proteins: NP_114412.2  
    ENSEMBL proteins: 
     ENSP00000339692   ENSP00000409767   ENSP00000473555   ENSP00000413468   ENSP00000334543  
     ENSP00000363538  

    Human Recombinant Protein Products for RASSF4: 
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    Novus Biologicals RASSF4 Protein
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    Browse Sino Biological Recombinant Proteins
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    Cloud-Clone Corp. Proteins for RASSF4 


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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR011524 SARAH_dom
     IPR000159 Ras-assoc

    Graphical View of Domain Structure for InterPro Entry Q9H2L5

    ProtoNet protein and cluster: Q9H2L5

    1 Blocks protein domain: IPB000159 RA domain

    UniProtKB/Swiss-Prot: RASF4_HUMAN, Q9H2L5
    Similarity: Contains 1 Ras-associating domain
    Similarity: Contains 1 SARAH domain


    RASSF4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RASF4_HUMAN, Q9H2L5
    Function: Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle
    arrest

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    RASSF4 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for RASSF4:
     Increased gamma-H2AX phosphory 

         1 MGI phenotypic allele for Rassf4 (no phenotypes)

    RASSF4 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Rassf4tm1Lex for RASSF4

       inGenious Targeting Laboratory - Custom generated mouse model solutions for RASSF4 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for RASSF4

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    8 QIAGEN miScript miRNA Assays for microRNAs that regulate RASSF4:
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    SwitchGear 3'UTR luciferase reporter plasmidRASSF4 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RASSF4


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RASSF4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    5/8 Interacting proteins for RASSF4 (Q9H2L51, 3 ENSP000003396924) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    STK4Q130431, 3, ENSP000003618924EBI-2933362,EBI-367376 I2D: score=3 STRING: ENSP00000361892
    STK3Q131883, ENSP000003905004I2D: score=1 STRING: ENSP00000390500
    HMGB1P094293, ENSP000003430404I2D: score=1 STRING: ENSP00000343040
    RASSF3Q86WH23, ENSP000003366164I2D: score=1 STRING: ENSP00000336616
    SAV1Q9H4B63, ENSP000003247294I2D: score=1 STRING: ENSP00000324729
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007049cell cycle IEA--
    GO:0007165signal transduction IEA--

    RASSF4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RASSF4 (RASF4)

    1 HMDB Compound for RASSF4    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--

    Search CenterWatch for drugs/clinical trials and news about RASSF4 / RASF4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RASSF4 gene (2 alternative transcripts): 
    NM_032023.3  NM_178145.1  

    Unigene Cluster for RASSF4:

    Ras association (RalGDS/AF-6) domain family member 4
    Hs.522895  [show with all ESTs]
    Unigene Representative Sequence: AB209446
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000489171(uc001jbo.3 uc001jbp.3) ENST00000340258 ENST00000427758
    ENST00000483709 ENST00000462822 ENST00000428466 ENST00000472561 ENST00000465735
    ENST00000471941 ENST00000471808 ENST00000484477 ENST00000493490 ENST00000334940(uc009xmn.3 uc001jbt.3)
    ENST00000374417(uc001jbq.3)

    miRNA
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    8 QIAGEN miScript miRNA Assays for microRNAs that regulate RASSF4:
    hsa-miR-30c hsa-miR-153 hsa-miR-30a hsa-miR-548g hsa-miR-1298 hsa-miR-30b hsa-miR-30d hsa-miR-30e
    SwitchGear 3'UTR luciferase reporter plasmidRASSF4 3' UTR sequence
    Inhib. RNA
    Products:
         
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RASSF4
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RASSF4

    Additional mRNA sequence: 

    AB209446.1 AF260335.1 AK055763.1 AK311531.1 AL713716.1 AY216713.1 AY216714.1 AY216715.1 
    BC032593.1 

    24 DOTS entries:

    DT.92429483  DT.121228415  DT.121228374  DT.314002  DT.95331702  DT.95331719  DT.414753  DT.100031488 
    DT.121228458  DT.121228325  DT.70103013  DT.100031490  DT.95331681  DT.121228229  DT.40190303  DT.75100251 
    DT.100738680  DT.100790063  DT.121228366  DT.121228367  DT.121228470  DT.70103014  DT.92429487  DT.121228235 

    24/175 AceView cDNA sequences (see all 175):

    BF590669 AA789027 NM_032023 AY216715 AI354606 BM453296 BC032593 AI479607 
    AK092770 BM931898 BM713162 BG817997 CD108069 BQ637692 BU621844 AI973274 
    BM702994 AV681759 AA584646 AY216714 AV708676 NM_178145 CA394478 AI811712 

    GeneLoc Exon Structure

    5/19 Alternative Splicing Database (ASD) splice patterns (SP) for RASSF4 (see all 19)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b · 7c · 7d · 7e ^ 8a · 8b · 8c ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b ·
    SP1:                          -     -           -     -           -     -     -     -     -                                               -           -     -   
    SP2:                          -     -     -           -           -     -     -     -     -                                               -           -     -   
    SP3:                          -     -           -     -           -     -     -     -     -     -                                         -           -     -   
    SP4:                                            -     -           -     -     -     -     -                                               -           -     -   
    SP5:                                                              -     -     -     -     -                                               -           -     -   

    ExUns: 12c ^ 13a · 13b · 13c ^ 14a · 14b · 14c · 14d ^ 15a · 15b
    SP1:  -                 -                                       
    SP2:  -                 -                                       
    SP3:  -                 -                                       
    SP4:  -                 -                                       
    SP5:  -                 -                                       


    ECgene alternative splicing isoforms for RASSF4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RASSF4 expression in normal human tissues (normalized intensities)      RASSF4 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGTGCGGAA
    RASSF4 Expression
    About this image


    RASSF4 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/12 selected tissues (see all 12) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Choroid Plexus Progenitor Cells Choroid Plexus
             Medulla Oblongata
             ganglion/cranial/trigeminal V   
     
     Blood (Muscoskeletal System)    fully expand to see all 2 entries
             Human Mesenchymal Stem Cell-bone marrow (HMSC-Bone Marrow)   
             cd14+ cells   
     
     Nose (Sensory Organs)    fully expand to see all 2 entries
             sensory organ/nose/nasal cavity   
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Mesencephalic Floor Plate
     
     Peripheral Nervous System (Nervous System)
             spinal/ganglion/dorsal root ganglion   

    See RASSF4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RASSF4

    SOURCE GeneReport for Unigene cluster: Hs.522895

    UniProtKB/Swiss-Prot: RASF4_HUMAN, Q9H2L5
    Tissue specificity: Widely expressed. Frequently down-regulated in tumor cell lines

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RASSF4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for RASSF4 gene from 3/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rassf41 , 5 Ras association (RalGDS/AF-6) domain family member 4 less1, 5 82.97(n)1
    84.74(a)1
      6 (53.83 cM)5
    2133911  NM_178045.41  NP_835146.31 
     1166330085 
    zebrafish
    (Danio rerio)
    Actinopterygii rassf46
    Ras association (RalGDS/AF-6) domain family member...
    56(a)
    1 ↔ 1
    13(30888421-30924062)
    fruit fly
    (Drosophila melanogaster)
    Insecta Rassf1 Ras association family member 48.18(n)
    36.45(a)
      42734  NM_142869.4  NP_651126.3 


    ENSEMBL Gene Tree for RASSF4 (if available)
    TreeFam Gene Tree for RASSF4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RASSF4 gene
    RASSF22  RASSF62  
    2 SIMAP similar genes for RASSF4 using alignment to 5 protein entries:     RASF4_HUMAN (see all proteins):
    RASSF2    RASSF6

    RASSF4 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/667 SNPs in RASSF4 are shown (see all 667)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs754489571,2
    C,F--45457162(+) GATTAT/AAGTTA 1 -- int11Minor allele frequency- A:0.03EA 120
    rs1145573831,2
    C--45457239(+) AGTCAC/GAGAGC 1 -- int10--------
    rs1398394931,2
    --45457469(+) AGGCCC/TGGAAC 1 -- int10--------
    rs1168635891,2
    C,F--45457470(+) GGCCCG/AGAACC 1 -- int11Minor allele frequency- A:0.01NA 120
    rs747791441,2
    C,F--45457554(+) AAGAGC/TCCTGA 1 -- int11Minor allele frequency- T:0.12EA 120
    rs1453375741,2
    --45457612(+) AGAGAC/TGGCGC 1 -- int10--------
    rs1846911301,2
    --45457616(+) ACGGCA/GCAACA 1 -- int10--------
    rs1903584151,2
    --45457722(+) CAGCAG/TAGATT 1 -- int10--------
    rs1929513061,2
    --45457785(+) TCCCTA/GCAGTG 1 -- int10--------
    rs1851563971,2
    --45457795(+) GATATA/GCAAAT 1 -- int10--------

    HapMap Linkage Disequilibrium report for RASSF4 (45454855 - 45490172 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for RASSF4:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv526734CNV Loss19592680
    nsv831846CNV Loss17160897
    nsv831845CNV Gain17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610559    OMIM disorders: --

    4 diseases for RASSF4:    About MalaCards
    macrocephaly, alopecia, cutis laxa, and scoliosis    nasopharyngitis    alzheimer's disease    leukemia


    RASSF4 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): RASSF4
    Human Genome Epidemiology (HuGE) Navigator: RASSF4 (2 documents)

    Export disorders for RASSF4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RASSF4 gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with RASSF4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Association studies of 23 positional/functional candidate genes on chromosome 10 in late-onset Alzheimer's disease. (PubMed id 17373700)1, 4 Morgan A.R....Williams J. (2007)
    2. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. RASSF4/AD037 is a potential ras effector/tumor suppressor of the RASSF family. (PubMed id 15574778)1, 2 Eckfeld K.... Clark G.J. (2004)
    5. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
    6. Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (2013)
    7. Network organization of the human autophagy system. (PubMed id 20562859)1 Behrends C....Harper J.W. (2010)
    8. Acquired variation outweighs inherited variation in w hole genome analysis of methotrexate polyglutamate accumulation in leukemia. (PubMed id 19066393)1 French D....Relling M.V. (2009)
    9. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    10. Aberrant methylation of RASSF4/AD037 in nasopharyngeal carcinoma. (PubMed id 15375500)1 Chow L.S....Huang D.P. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 83937 HGNC: 20793 AceView: RASSF4 Ensembl:ENSG00000107551 euGenes: HUgn83937
    ECgene: RASSF4 H-InvDB: RASSF4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RASSF4 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RASSF4 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RASSF4 gene:
    Search GeneIP for patents involving RASSF4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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