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RASSF3 Gene

protein-coding   GIFtS: 53
GCID: GC12P065004

Ras Association (RalGDS/AF-6) Domain Family Member 3

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ras Association (RalGDS/AF-6) Domain Family Member 31 2
RASSF52
Ras Association (RalGDS/AF-6) Domain Family 32
Ras Association Domain-Containing Protein 32

External Ids:    HGNC: 142711   Entrez Gene: 2833492   Ensembl: ENSG000001531797   OMIM: 6070195   UniProtKB: Q86WH23   

Export aliases for RASSF3 gene to outside databases

Previous GC identifers: GC12U990170 GC12P064721 GC12P063290 GC12P062056


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RASSF3 Gene:
The RAS oncogene (MIM 190020) is mutated in nearly one-third of all human cancers. Members of the RAS superfamily
are plasma membrane GTP-binding proteins that modulate intracellular signal transduction pathways. A subfamily of
RAS effectors, including RASSF3, share a RAS association (RA) domain.(supplied by OMIM, Jul 2003)

GeneCards Summary for RASSF3 Gene:
RASSF3 (Ras association (RalGDS/AF-6) domain family member 3) is a protein-coding gene. Diseases associated with RASSF3 include low tension glaucoma, and glaucoma. GO annotations related to this gene include identical protein binding. An important paralog of this gene is RASSF5.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000012.12  NT_029419.13  NC_018923.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RASSF3 gene promoter:
         FOXI1   HFH-3   Sox5   POU2F1a   MyoD   Hand1   Msx-1   Tal-1beta   E47   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): RASSF3 promoter sequence
   Search Chromatin IP Primers for RASSF3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RASSF3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q14.2   Ensembl cytogenetic band:  12q14.2   HGNC cytogenetic band: 12q14.2

RASSF3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RASSF3 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P065004:  view genomic region     (about GC identifiers)

Start:
65,004,293 bp from pter      End:
65,091,347 bp from pter
Size:
87,055 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: RASF3_HUMAN, Q86WH2 (See protein sequence)
Recommended Name: Ras association domain-containing protein 3  
Size: 238 amino acids; 27562 Da
Caution: Was termed (Ref.1) RASSF5
Secondary accessions: Q86WH1
Alternative splicing: 2 isoforms:  Q86WH2-1   Q86WH2-2   

Explore the universe of human proteins at neXtProt for RASSF3: NX_Q86WH2

Explore proteomics data for RASSF3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RASSF3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_835463.1  
    ENSEMBL proteins: 
     ENSP00000283172   ENSP00000443021   ENSP00000336616  

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    Cloud-Clone Corp. CLIAs for RASSF3


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR011524 SARAH_dom
     IPR000159 Ras-assoc

    Graphical View of Domain Structure for InterPro Entry Q86WH2

    ProtoNet protein and cluster: Q86WH2

    UniProtKB/Swiss-Prot: RASF3_HUMAN, Q86WH2
    Similarity: Contains 1 Ras-associating domain
    Similarity: Contains 1 SARAH domain


    RASSF3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0042802identical protein binding IPI--
         
    RASSF3 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RASSF3
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RASSF3
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    miRNA
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    miRTarBase miRNAs that target RASSF3:
    hsa-mir-18a-5p (MIRT031332), hsa-mir-20a-3p (MIRT038969), hsa-mir-193b-3p (MIRT016387)

    Block miRNA regulation of human, mouse, rat RASSF3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RASSF3 (see all 81):
    hsa-miR-576-3p hsa-miR-100* hsa-miR-3938 hsa-miR-106a hsa-miR-219-5p hsa-miR-550a* hsa-miR-93 hsa-miR-130b
    SwitchGear 3'UTR luciferase reporter plasmidRASSF3 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for RASSF3
    Predesigned siRNA for gene silencing in human, mouse, rat RASSF3

    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector: RASSF3 (NM_178169)
    Browse Sino Biological Human cDNA Clones
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RASSF3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RASF3_HUMAN, Q86WH2: Cytoplasm. Cytoplasm, cytoskeleton. Note=Localized to microtubules in vascular endothelial
    cells
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    plasma membrane4
    cytosol3
    nucleus2
    extracellular1
    mitochondrion1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005874microtubule IEA--
    GO:0005886plasma membrane IDA--

    RASSF3 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for RASSF3
        Transendothelial Migration of Leukocytes


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RASSF3
    Interactions:

        Search GeneGlobe Interaction Network for RASSF3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 16)

    Selected Interacting proteins for RASSF3 (Q86WH21, 3 ENSP000003366164) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    STK3Q131881, 3, ENSP000003905004EBI-2845202,EBI-992580 I2D: score=1 STRING: ENSP00000390500
    STK4Q130431, 3, ENSP000003618924EBI-2845202,EBI-367376 I2D: score=1 STRING: ENSP00000361892
    RASSF2P507493, ENSP000003686844I2D: score=1 STRING: ENSP00000368684
    RASSF4Q9H2L53, ENSP000003396924I2D: score=1 STRING: ENSP00000339692
    SAV1Q9H4B63, ENSP000003247294I2D: score=1 STRING: ENSP00000324729
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction IEA--

    RASSF3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RASSF3 (RASF3)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for RASSF3 gene: 
    NM_178169.3  

    Unigene Cluster for RASSF3:

    Ras association (RalGDS/AF-6) domain family member 3
    Hs.643605  [show with all ESTs]
    Unigene Representative Sequence: NM_178169
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000283172 ENST00000542104(uc001ssd.3 uc009zqn.3 uc001sse.3)
    ENST00000540088 ENST00000336061
    miRNA
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    Block miRNA regulation of human, mouse, rat RASSF3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RASSF3 (see all 81):
    hsa-miR-576-3p hsa-miR-100* hsa-miR-3938 hsa-miR-106a hsa-miR-219-5p hsa-miR-550a* hsa-miR-93 hsa-miR-130b
    SwitchGear 3'UTR luciferase reporter plasmidRASSF3 3' UTR sequence
    Inhib. RNA
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RASSF3
    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RASSF3
      QuantiTect SYBR Green Assays in human, mouse, rat RASSF3
      QuantiFast Probe-based Assays in human, mouse, rat RASSF3

    Additional mRNA sequence: 

    AY217662.1 BC100949.2 BC100950.1 BC100951.1 BC100952.1 NR_040718.1 

    6 DOTS entries:

    DT.412610  DT.95354287  DT.121114211  DT.40302273  DT.91872275  DT.92052103 

    12 AceView cDNA sequences:

    NM_178169 AY217663 AY217662 BU182700 BF896651 BQ050672 BU556605 BM562361 
    AA573427 AA401810 BU940690 BF737560 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for RASSF3    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5
    SP1:                              
    SP2:              -               


    ECgene alternative splicing isoforms for RASSF3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RASSF3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGAATCGAAA
    RASSF3 Expression
    About this image


    RASSF3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Blood (Hematopoietic System)
             Granulocytes Peripheral Blood
    RASSF3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RASSF3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.643605

    UniProtKB/Swiss-Prot: RASF3_HUMAN, Q86WH2
    Tissue specificity: Widely expressed

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RASSF3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for RASSF3 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rassf31 , 5 Ras association (RalGDS/AF-6) domain family member more1, 5 88.46(n)1
    94.37(a)1
      10 (69.70 cM)5
    1926781  NM_138956.31  NP_620406.11 
     1214103505 
    chicken
    (Gallus gallus)
    Aves RASSF31 Ras association (RalGDS/AF-6) domain family member more 79.66(n)
    80.08(a)
      417828  NM_001007851.1  NP_001007852.1 
    lizard
    (Anolis carolinensis)
    Reptilia RASSF36
    Ras association (RalGDS/AF-6) domain family member...
    65(a)
    1 ↔ 1
    5(50373845-50429041)
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ029223.12   -- 78.15(n)    BJ029223.1 
    zebrafish
    (Danio rerio)
    Actinopterygii rassf36
    Ras association (RalGDS/AF-6) domain family member...
    41(a)
    1 ↔ 1
    4(4412934-4464998) ENSDARG00000059064
    worm
    (Caenorhabditis elegans)
    Secernentea rsf-16
    Protein RSF-1, isoform a
    10(a)
    1 → many
    II(11306399-11311940) WBGene00011995


    ENSEMBL Gene Tree for RASSF3 (if available)
    TreeFam Gene Tree for RASSF3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RASSF3 gene
    RASSF52  RASSF12  
    3 SIMAP similar genes for RASSF3 using alignment to 2 protein entries:     RASF3_HUMAN (see all proteins):
    RASSF5    RASSF1    FLJ00186

    RASSF3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RASSF3 (see all 1759)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1161932261,2
    C,F--65002368(+) CCATCG/ACGCCC 2 -- us2k11Minor allele frequency- A:0.09WA 118
    rs1490025141,2
    --65002382(+) CAATAA/CAGCAT 2 -- us2k10--------
    rs1438008181,2
    C--65002484(+) TTAAGC/TCCTTA 2 -- us2k10--------
    rs1464301801,2
    C--65002497(+) CTACAC/TATTAT 2 -- us2k10--------
    rs1446866191,2
    --65002595(+) AAAGCA/CCTATT 2 -- us2k10--------
    rs759448641,2
    C,F--65002654(+) TGGGTG/TAAACT 2 -- us2k11Minor allele frequency- T:0.09WA 118
    rs743409851,2
    C--65002711(+) GCCGAG/AAAGAA 2 -- us2k12Minor allele frequency- A:0.10CSA WA 120
    rs796307351,2
    F--65002824(+) GGATGT/AGTAAG 2 -- us2k11Minor allele frequency- A:0.03WA 118
    rs1385830111,2
    --65002943(+) CTGTAG/TTCCAC 2 -- us2k10--------
    rs65815801,2
    C,F,A,H--65002969(+) ACCGAG/TACCAA 2 -- us2k140Minor allele frequency- N:0.00EA NA NS WA CSA 3757

    HapMap Linkage Disequilibrium report for RASSF3 (65004293 - 65091347 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for RASSF3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2387704CNV Deletion18987734
    dgv298e199CNV Deletion23128226
    esv2446886CNV Deletion19546169
    nsv832444CNV Loss17160897
    nsv524627CNV Loss19592680
    nsv818921CNV Loss17921354
    nsv438218CNV Loss16468122
    nsv515833CNV Loss19592680
    nsv832443CNV Loss17160897
    dgv1443n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RASSF3
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 607019    OMIM disorders: --

    5 diseases for RASSF3:    
    About MalaCards
    low tension glaucoma    glaucoma    hepatitis b    hepatitis
    endotheliitis


    RASSF3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): RASSF3
    Human Genome Epidemiology (HuGE) Navigator: RASSF3 (4 documents)

    Export disorders for RASSF3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RASSF3 gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with RASSF3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Local activation of Rap1 contributes to directional vascular endothelial cell migration accompanied by extension of microtubules on which RAPL, a Rap1-associating molecule, localizes. (PubMed id 15569673)1, 2 Fujita H.... Mochizuki N. (J. Biol. Chem. 2005)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. RASSF3 and NORE1: identification and cloning of two human homologues of the putative tumor suppressor gene RASSF1. (PubMed id 11965544)1, 2 Tommasi S....Pfeifer G.P. (Oncogene 2002)
    4. Silencing of RASSF3 by DNA hypermethylation is associated with tumorigenesis in somatotroph adenomas. (PubMed id 23555615)1 Peng H....Liao J. (PLoS ONE 2013)
    5. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    6. Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. (PubMed id 24255178)1 Couzens A.L....Gingras A.C. (Sci Signal 2013)
    7. The RASSF3 candidate tumor suppressor induces apoptosis and G1-S cell-cycle arrest via p53. (PubMed id 22593196)1 Kudo T....Hata Y. (Cancer Res. 2012)
    8. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    9. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    10. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (Genes Immun. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 283349 HGNC: 14271 AceView: RASSF3 Ensembl:ENSG00000153179 euGenes: HUgn283349
    ECgene: RASSF3 H-InvDB: RASSF3

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RASSF3 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RASSF3 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
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    Patent Information for RASSF3 gene:
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