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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RASSF2 Gene

protein-coding   GIFtS: 60
GCID: GC20M004760

Ras Association (RalGDS/AF-6) Domain Family Member 2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ras Association (RalGDS/AF-6) Domain Family Member 21 2     Ras Association (RalGDS/AF-6) Domain Family 22
Centromere Protein 341 2     Ras Association Domain-Containing Protein 22
CENP-342     KIAA01683
RASFADIN2     

External Ids:    HGNC: 98831   Entrez Gene: 97702   Ensembl: ENSG000001012657   OMIM: 6094925   UniProtKB: P507493   

Export aliases for RASSF2 gene to outside databases

Previous GC identifers: GC20M004748 GC20M004755 GC20M004708


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RASSF2 Gene:
This gene encodes a protein that contains a Ras association domain. Similar to its cattle and sheep counterparts,
this gene is located near the prion gene. Two alternatively spliced transcripts encoding the same isoform have
been reported. (provided by RefSeq, Jul 2008)

GeneCards Summary for RASSF2 Gene: 
RASSF2 (Ras association (RalGDS/AF-6) domain family member 2) is a protein-coding gene. Diseases associated with RASSF2 include thyroid cancer, and oral squamous cell carcinoma. GO annotations related to this gene include protein binding. An important paralog of this gene is RASSF4.

UniProtKB/Swiss-Prot: RASF2_HUMAN, P50749
Function: Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell
cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation

Gene Wiki entry for RASSF2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NT_011387.8  NC_018931.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RASSF2 gene promoter:
         NF-AT4   SRY   NF-AT2   IRF-1   NF-AT1   NF-AT   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRASSF2 promoter sequence
   Search SABiosciences Chromatin IP Primers for RASSF2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RASSF2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20p13   Ensembl cytogenetic band:  20p13   HGNC cytogenetic band: 20p13

RASSF2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RASSF2 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20M004760:  view genomic region     (about GC identifiers)

Start:
4,760,669 bp from pter      End:
4,804,291 bp from pter
Size:
43,623 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RASF2_HUMAN, P50749 (See protein sequence)
Recommended Name: Ras association domain-containing protein 2  
Size: 326 amino acids; 37790 Da
Subunit: Interacts directly with activated KRAS in a GTP-dependent manner. Interacts (via SARAH domain) with
STK3/MST2 AND STK4/MST1
Subcellular location: Nucleus. Cytoplasm. Note=Translocates to the cytoplasm in the presence of STK3/MST2 AND
STK4/MST1
Sequence caution: Sequence=BAA11485.2; Type=Erroneous initiation;
Secondary accessions: A6NIX9 A8K5Z3 Q17S06 Q53HD0 Q6AHZ2

Explore the universe of human proteins at neXtProt for RASSF2: NX_P50749

Explore proteomics data for RASSF2 at MOPED 

Post-translational modifications:

  • UniProtKB: Phosphorylated by STK3/MST2 and STK4/MST1
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P50749

  • RASSF2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RASSF2 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_055552.1  NP_739580.1  

    ENSEMBL proteins: 
     ENSP00000368710   ENSP00000368684  

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    Cloud-Clone Corp. Proteins for RASSF2 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--

    RASSF2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR011524 SARAH_dom
     IPR000159 Ras-assoc

    Graphical View of Domain Structure for InterPro Entry P50749

    ProtoNet protein and cluster: P50749

    1 Blocks protein domain: IPB000159 RA domain

    UniProtKB/Swiss-Prot: RASF2_HUMAN, P50749
    Similarity: Contains 1 Ras-associating domain
    Similarity: Contains 1 SARAH domain


    RASSF2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RASF2_HUMAN, P50749
    Function: Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell
    cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI12732644
         
    RASSF2 for ontologies           About GeneDecksing


    Phenotypes:
         7 MGI mutant phenotypes (inferred from 1 allele(MGI details for Rassf2):
     cellular  growth/size  hematopoietic system  immune system  liver/biliary system 
     mortality/aging  skeleton 

    RASSF2 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Rassf2tm1Dlim for RASSF2

       inGenious Targeting Laboratory - Custom generated mouse model solutions for RASSF2 
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RASSF2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RASSF2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    5/10 Interacting proteins for RASSF2 (P507491, 3 ENSP000003686844) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    STK4Q130431, 3, ENSP000003618924EBI-960081,EBI-367376 I2D: score=3 STRING: ENSP00000361892
    KRASP011161, 3, ENSP000002560784EBI-960081,EBI-367415 I2D: score=5 STRING: ENSP00000256078
    HRASP011123, ENSP000003098454I2D: score=3 STRING: ENSP00000309845
    STK3Q131883, ENSP000003905004I2D: score=3 STRING: ENSP00000390500
    RASSF5Q8WWW03, ENSP000003474434I2D: score=1 STRING: ENSP00000347443
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007049cell cycle IEA--
    GO:0007165signal transduction IEA--

    RASSF2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RASSF2 (RASF2)

    1 HMDB Compound for RASSF2    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--

    Search CenterWatch for drugs/clinical trials and news about RASSF2 / RASF2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RASSF2 gene (2 alternative transcripts): 
    NM_014737.2  NM_170774.1  

    Unigene Cluster for RASSF2:

    Ras association (RalGDS/AF-6) domain family member 2
    Hs.631504  [show with all ESTs]
    Unigene Representative Sequence: AY154470
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000478553(uc002wlc.3) ENST00000379400(uc002wlf.3) ENST00000379376(uc002wld.3)

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    Additional mRNA sequence: 

    AK222650.1 AK291458.1 AK307232.1 AK309635.1 AY154470.1 AY154471.1 AY154472.1 BC110385.1 
    BC117118.1 BC117120.1 D79990.1 

    19 DOTS entries:

    DT.115905  DT.99995990  DT.91755691  DT.100787784  DT.100829463  DT.91875070  DT.120809450  DT.120809420 
    DT.95084873  DT.120809667  DT.120809927  DT.120809421  DT.100787791  DT.95255079  DT.300279  DT.100787785 
    DT.100787792  DT.120809664  DT.120809885 

    24/233 AceView cDNA sequences (see all 233):

    BQ059714 AW504586 AA927714 CB153320 CR620887 NM_170774 AI948613 AW575914 
    AA432161 BF939935 BM672748 BU430781 NM_014737 D79990 AI161346 AI355582 
    BU730128 BQ015590 BF002763 AI051741 AI015986 W60624 N63510 AY154470 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for RASSF2 (see all 10)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b · 8c ^ 9 ^ 10 ^ 11a · 11b · 11c ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16
    SP1:        -           -     -                 -           -     -     -     -     -                                                               
    SP2:                    -     -                 -           -     -     -     -     -                                                               
    SP3:                                                                                                                          -                     
    SP4:                                                                          -                                               -                     
    SP5:        -     -     -     -                 -           -     -     -     -     -                                                               


    ECgene alternative splicing isoforms for RASSF2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RASSF2 expression in normal human tissues (normalized intensities)      RASSF2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACTTGATTCA
    RASSF2 Expression
    About this image


    RASSF2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/12 selected tissues (see all 12) fully expand
     
     Endothelium (Cardiovascular System)    fully expand to see all 4 entries
             Endothelial Cells Blood Brain Barrier
             Human Choroid Plexus Endothelial Cells (HCPEC)   
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Endothelial Cells Blood Brain Barrier
             Human Brain Microvascular Endothelial Cells (HBMEC)   
     
     Blood Brain Barrier (Nervous System)    fully expand to see all 2 entries
             Endothelial Cells Blood Brain Barrier
     
     Blood (Hematopoietic System)    fully expand to see all 2 entries
             Bone Marrow CD33+ Cells   
     
     Kidney (Urinary System)
             Metanephros

    See RASSF2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RASSF2

    SOURCE GeneReport for Unigene cluster: Hs.631504

    UniProtKB/Swiss-Prot: RASF2_HUMAN, P50749
    Tissue specificity: Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently
    down-regulated in lung tumor cell lines

        SABiosciences Expression via Pathway-Focused PCR Array including RASSF2: 
              Lung Cancer in human mouse rat

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for RASSF2 gene from 6/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rassf21 , 5 Ras association (RalGDS/AF-6) domain family member more1, 5 87.32(n)1
    92.64(a)1
      2 (64.14 cM)5
    2156531  NM_175445.41  NP_780654.11 
     1319894155 
    chicken
    (Gallus gallus)
    Aves RASSF21 Ras association (RalGDS/AF-6) domain family member more 78.19(n)
    82.72(a)
      419521  NM_001030884.1  NP_001026055.1 
    lizard
    (Anolis carolinensis)
    Reptilia RASSF26
    Uncharacterized protein
    70(a)
    1 ↔ 1
    GL343968.1(68107-77450)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.82222 Transcribed sequence with moderate similarity to protein more 77.05(n)    CF523814.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufa04h122 wufa04h12 75.54(n)   334841  CD596037.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG46563   -- 35(a)     --


    ENSEMBL Gene Tree for RASSF2 (if available)
    TreeFam Gene Tree for RASSF2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RASSF2 gene
    RASSF42  RASSF62  
    2 SIMAP similar genes for RASSF2 using alignment to 2 protein entries:     RASF2_HUMAN (see all proteins):
    RASSF4    RASSF6

    RASSF2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1241 SNPs in RASSF2 are shown (see all 1241)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0358254
    A colorectal cancer sample4--see VAR_0358252 R H mis40--------
    rs38309741,2
    C--4732322(+) CCCTC-/TTTCTCT 2 -- int11Minor allele frequency- TT:0.00NA 2
    rs1833307291,2
    --4760186(+) TCCCCA/GTACCA 2 -- ds50010--------
    rs1856002981,2
    --4760292(+) CAGGGA/GGGCTT 2 -- ds50010--------
    rs130423031,2
    C,H--4760364(+) tccaaG/Aaggaa 2 -- ds50016Minor allele frequency- A:0.00NS EA NA 600
    rs605539741,2
    F--4760656(+) ACCCAG/TCCACG 2 -- ds50010--------
    rs786491701,2
    F--4760660(+) ATCCAC/TGGGGC 2 -- ds50011Minor allele frequency- T:0.02WA 118
    rs1824245601,2
    --4760819(+) CCAAAA/CGTTGA 2 -- ut310--------
    rs1866732431,2
    --4760899(+) GAAAAA/CCCTTC 2 -- ut310--------
    rs412794281,2
    C,F--4761049(+) AGGGGC/TGCTTC 2 -- ut312Minor allele frequency- T:0.05WA NA 238

    HapMap Linkage Disequilibrium report for RASSF2 (4760669 - 4804291 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for RASSF2:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv1413742CNV Insertion17803354
    esv29645CNV Loss19812545
    esv274965CNV Loss21479260
    nsv526507CNV Loss19592680
    nsv912629CNV Gain21882294
    nsv912628CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609492    OMIM disorders: --

    14 diseases for RASSF2:    About MalaCards
    thyroid cancer    oral squamous cell carcinoma    peritonitis    nasopharyngitis
    squamous cell carcinoma    gastric cancer    colorectal cancer    thyroiditis
    lung cancer    hepatitis b    hepatitis    adenocarcinoma
    endotheliitis    pancreatitis


    RASSF2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): RASSF2
    Human Genome Epidemiology (HuGE) Navigator: RASSF2 (1 document)

    Export disorders for RASSF2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RASSF2 gene, integrated from 9 sources (see all 42):
    (articles sorted by number of sources associating them with RASSF2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 8724849)1, 2, 3 Nagase T.... Nomura N. (1996)
    2. The Ras effector RASSF2 is a novel tumor-suppressor gene in human colorectal cancer. (PubMed id 16012945)1, 2, 9 Akino K.... Tokino T. (2005)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    4. RASSF2 associates with and stabilizes the proapoptoti c kinase MST2. (PubMed id 19525978)1, 2 Cooper W.N....Latif F. (2009)
    5. Local activation of Rap1 contributes to directional vascular endothelial cell migration accompanied by extension of microtubules on which RAPL, a Rap1-associating molecule, localizes. (PubMed id 15569673)1, 2 Fujita H.... Mochizuki N. (2005)
    6. CpG island promoter hypermethylation of a novel Ras-effector gene RASSF2A is an early event in colon carcinogenesis and correlates inversely with K-ras mutations. (PubMed id 15806169)1, 3 Hesson L.B....Latif F. (2005)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. RASSF2 is a novel K-Ras-specific effector and potential tumor suppressor. (PubMed id 12732644)1, 2 Vos M.D.... Clark G.J. (2003)
    9. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
    10. Epigenetic inactivation of the RAS-effector gene RASSF2 in lung cancers. (PubMed id 17549418)1, 9 Kaira K....Mori M. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9770 HGNC: 9883 AceView: RASSF2 Ensembl:ENSG00000101265 euGenes: HUgn9770
    ECgene: RASSF2 H-InvDB: RASSF2

    (According to HUGE)
    About This Section
    HUGE: KIAA0168

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RASSF2 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RASSF2 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RASSF2 gene:
    Search GeneIP for patents involving RASSF2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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