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RASL10B Gene

protein-coding   GIFtS: 43
GCID: GC17P034058

RAS-Like, Family 10, Member B

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RAS-Like, Family 10, Member B1 2
RRP172 3 5
Ras-Like Protein VTS586352 3
Ras-Related Protein 172 3
VTS586352
Ras-Like Protein Family Member 10B2

External Ids:    HGNC: 302951   Entrez Gene: 916082   Ensembl: ENSG000001411507   OMIM: 6121285   UniProtKB: Q96S793   

Export aliases for RASL10B gene to outside databases

Previous GC identifers: GC17P034204 GC17P031082 GC17P030243


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RASL10B Gene:
RASL10B (RAS-like, family 10, member B) is a protein-coding gene. Diseases associated with RASL10B include breast and colorectal cancer, and malaria. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RAP2C.

UniProtKB/Swiss-Prot: RSLAB_HUMAN, Q96S79
Function: May facilitate the release of atrial natriuretic peptide by cardiomyocytes and hence play a role in the
regulation of arterial pressure (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the RASL10B gene promoter:
         STAT1   FOXD3   STAT1beta   HNF-3beta   Tal-1beta   STAT1alpha   CREB   deltaCREB   ITF-2   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRASL10B promoter sequence
   Search Chromatin IP Primers for RASL10B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RASL10B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q12   Ensembl cytogenetic band:  17q12   HGNC cytogenetic band: 17q21.1

RASL10B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RASL10B gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P034058:  view genomic region     (about GC identifiers)

Start:
34,058,668 bp from pter      End:
34,070,540 bp from pter
Size:
11,873 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RSLAB_HUMAN, Q96S79 (See protein sequence)
Recommended Name: Ras-like protein family member 10B precursor  
Size: 203 amino acids; 23229 Da
Subunit: Interacts with CADPS (By similarity)
Secondary accessions: B3KV31

Explore the universe of human proteins at neXtProt for RASL10B: NX_Q96S79

Explore proteomics data for RASL10B at MOPED


See RASL10B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_201572.1  
ENSEMBL proteins: 
 ENSP00000268864  

RASL10B Human Recombinant Protein Products:

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RASL10B Assay Products:

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Cloud-Clone Corp. ELISAs for RASL10B
Cloud-Clone Corp. CLIAs for RASL10B


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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3 InterPro protein domains:
 IPR001806 Small_GTPase
 IPR027417 P-loop_NTPase
 IPR020849 Small_GTPase_Ras

Graphical View of Domain Structure for InterPro Entry Q96S79

ProtoNet protein and cluster: Q96S79

2 Blocks protein domains:
IPB001806 Transforming protein P21 RAS signature
IPB013684 Miro-like


UniProtKB/Swiss-Prot: RSLAB_HUMAN, Q96S79
Similarity: Belongs to the small GTPase superfamily. Ras family


RASL10B for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: RSLAB_HUMAN, Q96S79
Function: May facilitate the release of atrial natriuretic peptide by cardiomyocytes and hence play a role in the
regulation of arterial pressure (By similarity)

     Gene Ontology (GO): 3 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003924GTPase activity ----
GO:0005515protein binding ----
GO:0005525GTP binding IEA--
     
RASL10B for ontologies           About GeneDecksing


Phenotypes:
     1 GenomeRNAi human phenotype for RASL10B:
 Increased gamma-H2AX phosphory 

     1 MGI mutant phenotype (inferred from 1 allele(MGI details for Rasl10b):
 cellular 

RASL10B for phenotypes           About GeneDecksing

Animal Models:
     MGI mouse knock-out Rasl10btm1Eno for RASL10B

   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RASL10B
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RASL10B

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RASL10B
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RASL10B

miRNA
Products:
    
miRTarBase miRNAs that target RASL10B:
hsa-mir-877-3p (MIRT037118), hsa-mir-421 (MIRT039428), hsa-mir-331-3p (MIRT043503)

Block miRNA regulation of human, mouse, rat RASL10B using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate RASL10B (see all 76):
hsa-miR-1321 hsa-miR-1245 hsa-miR-629* hsa-miR-383 hsa-miR-149 hsa-miR-637 hsa-miR-29a* hsa-miR-3649
SwitchGear 3'UTR luciferase reporter plasmidRASL10B 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for RASL10B
Predesigned siRNA for gene silencing in human, mouse, rat RASL10B

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for RASL10B

Clone
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OriGene clones in human, mouse for RASL10B (see all 7)
OriGene ORF clones in mouse, rat for RASL10B
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: RASL10B (NM_033315)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for RASL10B
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RASL10B

Cell Line
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GenScript Custom overexpressing Cell Line Services for RASL10B
Browse ESI BIO Cell Lines and PureStem Progenitors for RASL10B 
In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RASL10B


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
RSLAB_HUMAN, Q96S79: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
plasma membrane5
mitochondrion2
cytosol1
extracellular1
nucleus1

Gene Ontology (GO): 3 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005622intracellular ----
GO:0005886plasma membrane IEA--
GO:0016020membrane ----

RASL10B for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RASL10B
Interactions:

    Search GeneGlobe Interaction Network for RASL10B

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

Selected Interacting proteins for RASL10B (ENSP000002688644) via UniProtKB, MINT, STRING, and/or I2D (see all 27)
InteractantInteraction Details
GeneCardExternal ID(s)
PARD6GENSP000003431444STRING: ENSP00000343144
WASENSP000003658914STRING: ENSP00000365891
ARHGAP1ENSP000003104914STRING: ENSP00000310491
ARHGDIAENSP000002693214STRING: ENSP00000269321
MCF2L2ENSP000003281184STRING: ENSP00000328118
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Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003050regulation of systemic arterial blood pressure by atrial natriuretic peptide ISS--
GO:0006184GTP catabolic process IEA--
GO:0007165signal transduction ----
GO:0007264small GTPase mediated signal transduction IEA--
GO:0015031protein transport ----

RASL10B for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for RASL10B (RSLAB)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for RASL10B gene: 
NM_033315.3  

2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000268864(uc002hju.3) ENST00000587350
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat RASL10B using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate RASL10B (see all 76):
hsa-miR-1321 hsa-miR-1245 hsa-miR-629* hsa-miR-383 hsa-miR-149 hsa-miR-637 hsa-miR-29a* hsa-miR-3649
SwitchGear 3'UTR luciferase reporter plasmidRASL10B 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for RASL10B
Predesigned siRNA for gene silencing in human, mouse, rat RASL10B
Clone
Products:
     
OriGene clones in human, mouse for RASL10B (see all 7)
OriGene ORF clones in mouse, rat for RASL10B
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: RASL10B (NM_033315)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for RASL10B
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RASL10B
Primer
Products:
    
OriGene qPCR primer pairs and template standards for RASL10B
OriGene qSTAR qPCR primer pairs in human, mouse for RASL10B
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RASL10B
  QuantiTect SYBR Green Assays in human, mouse, rat RASL10B
  QuantiFast Probe-based Assays in human, mouse, rat RASL10B

Selected AceView cDNA sequences (see all 60):

AB047296 BU678126 AI887398 BQ066955 BC041133 BP333947 BM704568 BX115083 
BM671709 CR602996 BM708024 AI500182 BU540583 NM_033315 BX428089 BM505734 
BE266409 AI914006 BX333800 BX349919 F30158 AA454603 AA432287 CD106926 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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RASL10B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: CCCCATCACC
RASL10B Expression
About this image

RASL10B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

RASL10B Protein Expression

UniProtKB/Swiss-Prot: RSLAB_HUMAN, Q96S79
Tissue specificity: Expressed at high levels in skeletal muscle and, at much lower levels, in heart, brain and
pancreas

    Custom PCR Arrays for RASL10B
Primer
Products:
OriGene qPCR primer pairs and template standards for RASL10B
OriGene qSTAR qPCR primer pairs in human, mouse for RASL10B
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RASL10B
QuantiTect SYBR Green Assays in human, mouse, rat RASL10B
QuantiFast Probe-based Assays in human, mouse, rat RASL10B
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RASL10B

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for RASL10B gene from Selected species (see all 12)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Rasl10b1 , 5 RAS-like, family 10, member B1, 5 93.76(n)1
99.01(a)1
  11 (50.30 cM)5
2769521  NM_001013386.21  NP_001013404.11 
 834091375 
chicken
(Gallus gallus)
Aves RASL10B1 RAS-like, family 10, member B 85.39(n)
91.63(a)
  771592  XM_001233673.3  XP_001233674.1 
lizard
(Anolis carolinensis)
Reptilia RASL10B6
RAS-like, family 10, member B
75(a)
1 ↔ 1
GL344864.1(17104-17286)
tropical clawed frog
(Xenopus tropicalis)
Amphibia rasl10b1 RAS-like, family 10, member B 77.18(n)
87.68(a)
  100489153  XM_004911629.1  XP_004911686.1 
zebrafish
(Danio rerio)
Actinopterygii rasl10a1 RAS-like, family 10, member A 63.88(n)
61.08(a)
  100004647  NM_001128366.1  NP_001121838.1 
fruit fly
(Drosophila melanogaster)
Insecta CG146691 CG14669 52.5(n)
42.51(a)
  40652  NM_141280.2  NP_649537.5 


ENSEMBL Gene Tree for RASL10B (if available)
TreeFam Gene Tree for RASL10B (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for RASL10B gene
RAP2C2  DIRAS12  RAP1B2  RASD22  RIT22  RAP2A2  RIT12  RAP1A2  
RAP2B2  RASD12  DIRAS22  RASL10A2  DIRAS32  
6 SIMAP similar genes for RASL10B using alignment to 2 protein entries:     RSLAB_HUMAN (see all proteins):
RASL10A    RAP1B    RAP1A    DIRAS2    RAP2B    RAP2A

RASL10B for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for RASL10B (see all 271)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 17 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
VAR_0363094
A breast cancer sample4--see VAR_0363092 V M mis40--------
rs1408093501,2
--34056696(+) TGTCCC/GTAAAA 1 -- us2k10--------
rs1145054571,2
F--34056762(+) AGGATT/GTTACA 1 -- us2k11Minor allele frequency- G:0.01WA 118
rs1894310021,2
--34056768(+) TTACAC/TACCTC 1 -- us2k10--------
rs1501415381,2
--34056930(+) AGGCTC/TATACC 1 -- us2k10--------
rs1382904071,2
--34057048(+) GAGCCA/GGAGCA 1 -- us2k10--------
rs1114354051,2
C,F--34057089(+) CAGGGT/CCCCAG 1 -- us2k12Minor allele frequency- C:0.08NA 122
rs1413073311,2
--34057207(+) GAGCCA/GGGTGC 1 -- us2k10--------
rs1450732711,2
--34057222(+) GCTCAC/TGCCTG 1 -- us2k10--------
rs1816267181,2
--34057280(+) AAGAGA/GTGGAG 1 -- us2k10--------

HapMap Linkage Disequilibrium report for RASL10B (34058668 - 34070540 bp)

Structural Variations
     Database of Genomic Variants (DGV) 1 variation for RASL10B:    About this table    
Variant IDTypeSubtypePubMed ID
nsv908080CNV Loss21882294

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing RASL10B
DNA2.0 Custom Variant and Variant Library Synthesis for RASL10B

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 612128    OMIM disorders: --

3 diseases for RASL10B:    
About MalaCards
breast and colorectal cancer    malaria    colorectal cancer


RASL10B for disorders           About GeneDecksing

Genetic Association Database (GAD): RASL10B

Export disorders for RASL10B gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for RASL10B gene, integrated from 10 sources (see all 13):
(articles sorted by number of sources associating them with RASL10B)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Regulation of atrial natriuretic peptide secretion by a novel Ras- like protein. (PubMed id 17984325)1, 2 Rybkin I.I.... Olson E.N. (J. Cell Biol. 2007)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  5. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
  6. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
  7. Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays. (PubMed id 19953087)1 Persaud A....Rotin D. (Mol. Syst. Biol. 2009)
  8. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)
  9. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
  10. Cloning and characterization of a novel small monomeric GTPase, RasL10B, with tumor suppressor potential. (PubMed id 17028781)1 Zou H....Cao K. (Biotechnol. Lett. 2006)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 91608 HGNC: 30295 AceView: RASL10B Ensembl:ENSG00000141150 euGenes: HUgn91608
ECgene: RASL10B H-InvDB: RASL10B

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for RASL10B Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for RASL10B gene:
Search GeneIP for patents involving RASL10B

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 OriGene Antibodies for RASL10B   OriGene RNAi products in human, mouse, rat for RASL10B  
 OriGene qPCR primer pairs and template standards for RASL10B   OriGene Protein Over-expression Lysate for RASL10B  
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 OriGene Custom Antibody Services for RASL10B   OriGene Custom Protein Services for RASL10B  

 
 
 Block miRNA regulation of human, mouse, rat RASL10B using miScript Target Protectors SeqTarget long-range PCR primers for resequencing RASL10B
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RASL10B Predesigned siRNA for gene silencing in human, mouse, rat RASL10B
 QuantiFast Probe-based Assays in human, mouse, rat RASL10B QuantiTect SYBR Green Assays in human, mouse, rat RASL10B
 Custom PCR Arrays for RASL10B Search Chromatin IP Primers for RASL10B
 Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RASL10B  Search GeneGlobe Interaction Network for RASL10B
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 GenScript Custom Purified and Recombinant Proteins Services for RASL10B GenScript cDNA clones with any tag delivered in your preferred vector for RASL10B
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 Search Tocris compounds for RASL10B (RSLAB)
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 Novus Tissue Slides
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 Browse ProSpec Recombinant Proteins
 Proteins for RASL10B
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 Browse ESI BIO Cell Lines and PureStem Progenitors for RASL10B
 Gene Synthesis
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 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RASL10B
 SwitchGear 3'UTR luciferase reporter plasmids for RASL10B
 SwitchGear Promoter luciferase reporter plasmids for RASL10B
 ThermoFisher Antibodies for RASL10B
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RASL10B
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RASL10B
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RASL10B
 Search LSBio for Antibodies for RASL10B
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GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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