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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RASGEF1A Gene

protein-coding   GIFtS: 50
GCID: GC10M043689

RasGEF Domain Family, Member 1A

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
RasGEF Domain Family, Member 1A1 2
CG48532
CG4853 Gene Product2
Ras-GEF Domain-Containing Family Member 1A2

External Ids:    HGNC: 242461   Entrez Gene: 2210022   Ensembl: ENSG000001989157   OMIM: 6145315   UniProtKB: Q8N9B83   

Export aliases for RASGEF1A gene to outside databases

Previous GC identifers: GC10M042973 GC10M043009 GC10M040217


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for RASGEF1A Gene: 
RASGEF1A (RasGEF domain family, member 1A) is a protein-coding gene. Diseases associated with RASGEF1A include hirschsprung's disease, and intrahepatic cholangiocarcinoma. GO annotations related to this gene include Ras guanyl-nucleotide exchange factor activity. An important paralog of this gene is RAPGEFL1.

UniProtKB/Swiss-Prot: RGF1A_HUMAN, Q8N9B8
Function: Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, KRAS, HRAS, and NRAS (in vitro).
Plays a role in cell migration




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NT_033985.7  NC_018921.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RASGEF1A gene promoter:
         STAT5B   GATA-3   Pax-5   HNF-4alpha2   Nkx2-5   LCR-F1   HNF-1A   PPAR-gamma1   HNF-1   PPAR-gamma2   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for RASGEF1A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RASGEF1A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q11.21   Ensembl cytogenetic band:  10q11.21   HGNC cytogenetic band: 10q11.21

RASGEF1A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RASGEF1A gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M043689:  view genomic region     (about GC identifiers)

Start:
43,689,983 bp from pter      End:
43,762,367 bp from pter
Size:
72,385 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RGF1A_HUMAN, Q8N9B8 (See protein sequence)
Recommended Name: Ras-GEF domain-containing family member 1A  
Size: 481 amino acids; 54556 Da
Secondary accessions: Q8TBF1
Alternative splicing: 2 isoforms:  Q8N9B8-1   Q8N9B8-2   

Explore the universe of human proteins at neXtProt for RASGEF1A: NX_Q8N9B8

Explore proteomics data for RASGEF1A at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8N9B8

  • RASGEF1A Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RASGEF1A Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001269791.1  NP_660356.2  

    ENSEMBL proteins: 
     ENSP00000363583   ENSP00000379155   ENSP00000379154   ENSP00000363579  

    Human Recombinant Protein Products for RASGEF1A: 
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for RASGEF1A 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular IEA--

    RASGEF1A for ontologies           About GeneDecksing



    RASGEF1A Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR008937 Ras_GEF
     IPR023578 Ras_GEF_dom
     IPR001895 RasGRF_CDC25
     IPR000651 Ras-like_Gua-exchang_fac_N

    Graphical View of Domain Structure for InterPro Entry Q8N9B8

    ProtoNet protein and cluster: Q8N9B8

    1 Blocks protein domain: IPB001895 Guanine-nucleotide dissociation stimulator CDC25

    UniProtKB/Swiss-Prot: RGF1A_HUMAN, Q8N9B8
    Similarity: Contains 1 N-terminal Ras-GEF domain
    Similarity: Contains 1 Ras-GEF domain


    RASGEF1A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RGF1A_HUMAN, Q8N9B8
    Function: Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, KRAS, HRAS, and NRAS (in vitro).
    Plays a role in cell migration

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005085guanyl-nucleotide exchange factor activity ----
    GO:0005088Ras guanyl-nucleotide exchange factor activity IDA17121879
         
    RASGEF1A for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for RASGEF1A:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for RASGEF1A 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for RASGEF1A

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RASGEF1A 
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    SwitchGear 3'UTR luciferase reporter plasmidRASGEF1A 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for RASGEF1A About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Integrated Breast Cancer Pathway
    Integrated Breast Cancer Pathway


    1 BioSystems Pathway for RASGEF1A
        Integrated Breast Cancer Pathway


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RASGEF1A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    5/9 Interacting proteins for RASGEF1A (ENSP000003791544) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000206292ENSP000003727134STRING: ENSP00000372713
    ENSG00000206308ENSP000003727464STRING: ENSP00000372746
    ENSG00000227317ENSP000004031544STRING: ENSP00000403154
    ENSG00000233890ENSP000003993884STRING: ENSP00000399388
    ENSG00000234258ENSP000003964864STRING: ENSP00000396486
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007264small GTPase mediated signal transduction IEA--
    GO:0016477cell migration IDA17121879
    GO:0046579positive regulation of Ras protein signal transduction IDA17121879
    GO:0051056regulation of small GTPase mediated signal transduction ----

    RASGEF1A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RASGEF1A (RGF1A)

    3 HMDB Compounds for RASGEF1A    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine diphosphate5'-GDP (see all 10)146-91-8--
    Guanosine monophosphate5'-GMP (see all 14)85-32-5--
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--

    Search CenterWatch for drugs/clinical trials and news about RASGEF1A / RGF1A

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RASGEF1A gene (2 alternative transcripts): 
    NM_001282862.1  NM_145313.3  

    Unigene Cluster for RASGEF1A:

    RasGEF domain family, member 1A
    Hs.125293  [show with all ESTs]
    Unigene Representative Sequence: AK127432
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000374459(uc001jao.1) ENST00000395810(uc001jap.1) ENST00000395809
    ENST00000374455 ENST00000472864
    miRNA
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    Inhib. RNA
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    Additional mRNA sequence: 

    AK095136.1 AK127432.1 BC022548.1 

    3 DOTS entries:

    DT.100744156  DT.100021634  DT.99931641 

    24/36 AceView cDNA sequences (see all 36):

    BU838456 AK127432 BX508269 AK095136 CA415243 CA773172 BE744303 BC022548 
    AI742833 BX097845 Z39259 AA883906 CA943165 NM_145313 AA324359 AI887949 
    BM824757 AI985897 BF338587 AW075808 BX279795 BE670730 AI203292 AI990592 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for RASGEF1A    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16a · 16b
    SP1:              -     -                 -                                                                                 
    SP2:                    -                 -                                                                                 
    SP3:                                      -                                                                                 
    SP4:              -     -     -           -                                                                                 
    SP5:                                                                                                                        


    ECgene alternative splicing isoforms for RASGEF1A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RASGEF1A expression in normal human tissues (normalized intensities)      RASGEF1A embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCTCTGGTCC
    RASGEF1A Expression
    About this image


    RASGEF1A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/1 selected tissues (see all 1) fully expand
     
     Inner Cell Mass (Early Embryonic Tissues)
             BG01V

    See RASGEF1A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RASGEF1A

    SOURCE GeneReport for Unigene cluster: Hs.125293

    UniProtKB/Swiss-Prot: RGF1A_HUMAN, Q8N9B8
    Tissue specificity: Detected in brain and spinal cord. Highly expressed in a number of intrahepatic
    cholangiocarcinoma tissue biopsies

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RASGEF1A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for RASGEF1A gene from 6/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rasgef1a1 , 5 RasGEF domain family, member 1A1, 5 89.12(n)1
    93.97(a)1
      6 (55.85 cM)5
    707271  NM_027526.11  NP_081802.11 
     1180663855 
    chicken
    (Gallus gallus)
    Aves RASGEF1A1 RasGEF domain family, member 1A 80.69(n)
    85.62(a)
      423631  XM_003641456.1  XP_003641504.1 
    lizard
    (Anolis carolinensis)
    Reptilia RASGEF1A6
    Uncharacterized protein
    80(a)
    1 ↔ 1
    GL343233.1(745855-893425)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.244252 Xenopus laevis transcribed sequence with weak similarity more 80.65(n)    CD301594.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG73696
    CG48536
    (see all 3)
    --
    29(a)
    23(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    3L(22734893-22741714)
    2R(13401710-13404950)
    worm
    (Caenorhabditis elegans)
    Secernentea R05G6.106
    Protein R05G6.10
    34(a)
    1 → many
    IV(7517446-7520367)


    ENSEMBL Gene Tree for RASGEF1A (if available)
    TreeFam Gene Tree for RASGEF1A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RASGEF1A gene
    RAPGEFL12  RAPGEF22  RASGRP42  RAPGEF62  RASGRP12  RAPGEF32  RAPGEF42  RASGEF1C2  
    RAPGEF52  RASGEF1B2  RASGRP22  RASGRP32  
    2 SIMAP similar genes for RASGEF1A using alignment to 2 protein entries:     RGF1A_HUMAN (see all proteins):
    RASGEF1B    RASGEF1C

    RASGEF1A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1563 SNPs in RASGEF1A are shown (see all 1563)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1826802721,2
    --43689616(+) TGCCCC/GCAGAG 1 -- ds50010--------
    rs765030581,2
    C--43689657(+) TCCATA/GCAGCC 1 -- ds50011Minor allele frequency- G:0.01NA 120
    rs1870487641,2
    --43689679(+) GGTATC/GCTGAA 1 -- ds50010--------
    rs1918993791,2
    --43689764(+) CTGAAC/TGTGCC 1 -- ds50010--------
    rs12549651,2
    C,F,A,H--43689853(+) AGTCTC/TTTGCC 1 -- ds500120Minor allele frequency- T:0.25NS EA NA 2496
    rs1853781441,2
    --43690096(+) CATCAA/CATCAG 1 -- ut310--------
    rs1379801121,2
    C--43690174(+) CACCCA/GTGAAG 1 -- ut310--------
    rs12549661,2
    C,H--43690189(+) CGTGGA/GTGTGT 1 -- ut31 ese314Minor allele frequency- G:0.02MN NA WA CSA EA 560
    rs112384721,2
    C,F--43690253(+) TTTCTC/TATCTC 1 -- ut31 ese34Minor allele frequency- T:0.13NA 126
    rs1421946641,2
    C--43690329(+) TGCAAA/GCACAC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for RASGEF1A (43689983 - 43762367 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for RASGEF1A:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2656730CNV Deletion23128226
    esv2669702CNV Deletion23128226
    nsv466881CNV Loss19166990
    nsv895086CNV Loss21882294
    nsv895085CNV Loss21882294
    nsv895084CNV Loss21882294
    dgv644n71CNV Loss21882294
    nsv825352CNV Gain20364138
    nsv825351CNV Gain20364138

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 614531    OMIM disorders: --

    4 diseases for RASGEF1A:    About MalaCards
    hirschsprung's disease    intrahepatic cholangiocarcinoma    cholangiocarcinoma    breast cancer


    RASGEF1A for disorders           About GeneDecksing

    Genetic Association Database (GAD): RASGEF1A

    Export disorders for RASGEF1A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RASGEF1A gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with RASGEF1A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genome-wide association study identifies NRG1 as a susceptibility locus for Hirschsprung's disease. (PubMed id 19196962)1, 4 Garcia-Barcelo M.M....Tam P.K. (2009)
    2. RasGEF1A and RasGEF1B are guanine nucleotide exchange factors that discriminate between Rap GTP-binding proteins and mediate Rap2-sp ecific nucleotide exchange. (PubMed id 19645719)1, 2 Yaman E....Tazebay U.H. (2009)
    3. Enhanced RASGEF1A expression is involved in the growth and migration of intrahepatic cholangiocarcinoma. (PubMed id 17121879)1, 2 Ura K.... Furukawa Y. (2006)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    6. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (2012)
    7. Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis. (PubMed id 20598377)4 Nischwitz S....Weber F. (2010)
    8. Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays. (PubMed id 19953087)1 Persaud A....Rotin D. (2009)
    9. Identifying candidate Hirschsprung disease-associated RET variants. (PubMed id 15759212)1 Burzynski G.M....Hofstra R.M. (2005)
    10. A common sex-dependent mutation in a RET enhancer underlies Hirschsprung disease risk. (PubMed id 15829955)1 Emison E.S....Chakravarti A. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 221002 HGNC: 24246 AceView: RASGEF1A Ensembl:ENSG00000198915 euGenes: HUgn221002
    ECgene: RASGEF1A H-InvDB: RASGEF1A

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RASGEF1A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RASGEF1A gene:
    Search GeneIP for patents involving RASGEF1A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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