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RASAL3 Gene

protein-coding   GIFtS: 50
GCID: GC19M015562

RAS Protein Activator Like 3

  Search for RASAL3
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RAS Protein Activator Like 31 2
RAS Protein Activator Like-32

External Ids:    HGNC: 261291   Entrez Gene: 649262   Ensembl: ENSG000001051227   UniProtKB: Q86YV03   

Export aliases for RASAL3 gene to outside databases

Previous GC identifers: GC19M015426 GC19M015132


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RASAL3 Gene:
RASAL3 (RAS protein activator like 3) is a protein-coding gene. GO annotations related to this gene include phospholipid binding and Ras GTPase activator activity. An important paralog of this gene is SYNGAP1.

UniProtKB/Swiss-Prot: RASL3_HUMAN, Q86YV0
Function: May function as a Ras GTPase-activating protein (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NT_011295.12  NC_018930.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RASAL3 gene promoter:
         GR   CP2   Sp1   AP-1   GR-beta   GR-alpha   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for RASAL3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RASAL3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.12   Ensembl cytogenetic band:  19p13.12   HGNC cytogenetic band: 19p13.12

RASAL3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RASAL3 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M015562:  view genomic region     (about GC identifiers)

Start:
15,562,435 bp from pter      End:
15,575,382 bp from pter
Size:
12,948 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RASL3_HUMAN, Q86YV0 (See protein sequence)
Recommended Name: RAS protein activator like-3  
Size: 1011 amino acids; 111898 Da
Sequence caution: Sequence=AAH30281.1; Type=Erroneous initiation; Sequence=BAB15064.1; Type=Erroneous initiation;
Sequence=BAC56928.1; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=BAC56928.1;
Type=Erroneous termination; Positions=723; Note=Translated as Arg;
Secondary accessions: Q8N2T9 Q9H735
Alternative splicing: 2 isoforms:  Q86YV0-1   Q86YV0-2   

Explore the universe of human proteins at neXtProt for RASAL3: NX_Q86YV0

Explore proteomics data for RASAL3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RASAL3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_075055.1  
    ENSEMBL proteins: 
     ENSP00000476634   ENSP00000341905   ENSP00000468841  

    RASAL3 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for RASAL3

     
    Search eBioscience for Proteins for RASAL3 

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    Cloud-Clone Corp. CLIAs for RASAL3
    Search eBioscience for ELISAs for RASAL3 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    5 InterPro protein domains:
     IPR001936 RasGAP
     IPR008936 Rho_GTPase_activation_prot
     IPR001849 Pleckstrin_homology
     IPR023152 RasGAP_CS
     IPR000008 C2_dom

    Graphical View of Domain Structure for InterPro Entry Q86YV0

    ProtoNet protein and cluster: Q86YV0

    3 Blocks protein domains:
    IPB000008 C2 domain
    IPB001849 Pleckstrin-like
    IPB001936 Ras GTPase-activating protein


    UniProtKB/Swiss-Prot: RASL3_HUMAN, Q86YV0
    Similarity: Contains 1 C2 domain
    Similarity: Contains 1 PH domain
    Similarity: Contains 1 Ras-GAP domain


    Find genes that share domains with RASAL3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RASL3_HUMAN, Q86YV0
    Function: May function as a Ras GTPase-activating protein (By similarity)

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005096GTPase activator activity ----
    GO:0005099Ras GTPase activator activity IBA--
    GO:0005515protein binding ----
         
    Find genes that share ontologies with RASAL3           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RASAL3
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RASAL3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RASAL3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RASAL3

    miRNA
    Products:
        
    miRTarBase miRNAs that target RASAL3:
    hsa-mir-615-3p (MIRT039709)

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    Predesigned siRNA for gene silencing in human, mouse, rat RASAL3

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    Browse Sino Biological Human cDNA Clones
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    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat RASAL3

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RASAL3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    plasma membrane3
    nucleus2
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005737cytoplasm IBA--
    GO:0031235intrinsic component of the cytoplasmic side of the plasma membrane IBA--
    GO:0070062extracellular vesicular exosome IDA--

    Find genes that share ontologies with RASAL3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RASAL3 About    
    See pathways by source

    SuperPathContained pathways About
    1Ras signaling pathway
    Ras signaling pathway0.36


    Find genes that share SuperPaths with RASAL3           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Kegg Pathway  (Kegg details for RASAL3):
        Ras signaling pathway

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RASAL3
    Interactions:

        Search GeneGlobe Interaction Network for RASAL3

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    4 Interacting proteins for RASAL3 (Q86YV03 ENSP000003419054) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    YWHAEP622583, ENSP000002643354I2D: score=3 STRING: ENSP00000264335
    YWHAZP631043, ENSP000003095034I2D: score=2 STRING: ENSP00000309503
    WNK1Q9H4A33, ENSP000003130594I2D: score=1 STRING: ENSP00000313059
    APCP250543I2D: score=2 
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction IEA--
    GO:0032320positive regulation of Ras GTPase activity IBA--
    GO:0046580negative regulation of Ras protein signal transduction IBA--
    GO:0051056regulation of small GTPase mediated signal transduction ----

    Find genes that share ontologies with RASAL3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RASAL3 (RASL3)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RASAL3 gene: 
    NM_022904.1  

    Unigene Cluster for RASAL3:

    RAS protein activator like 3
    Hs.136979  [show with all ESTs]
    Unigene Representative Sequence: AK024488
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000609274 ENST00000343625(uc002nbd.3 uc002nbe.2) ENST00000602101
    ENST00000599694 ENST00000595098 ENST00000597025 ENST00000608577
    miRNA
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    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat RASAL3
    Clone
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    GenScript: all cDNA clones in your preferred vector: RASAL3 (NM_022904)
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    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat RASAL3
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for RASAL3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RASAL3
      QuantiTect SYBR Green Assays in human, mouse, rat RASAL3
      QuantiFast Probe-based Assays in human, mouse, rat RASAL3

    Additional mRNA sequence: 

    AK024488.1 AK025091.1 AK122587.1 AL832868.1 BC030281.1 

    5 DOTS entries:

    DT.429889  DT.92011570  DT.97839526  DT.100711746  DT.40194796 

    Selected AceView cDNA sequences (see all 67):

    AA359127 BC030281 AI028474 AW661927 AK122587 AA767936 AL832868 AI697316 
    CR595796 BQ052406 AW440942 BX109514 AK024488 BX644896 BG758542 BX363502 
    CA307701 AI364659 BM922942 AA831257 BX363501 AA320236 CF135868 AK025091 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for RASAL3 (see all 10)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^ 18a · 18b ^ 19a · 19b
    SP1:                                                                                                                                                
    SP2:                                                                                                                                                
    SP3:                                                                                                                    -     -                     
    SP4:                                                                                                                                                
    SP5:                                                                                                                    -     -     -               


    ECgene alternative splicing isoforms for RASAL3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RASAL3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGACCAGCGC
    RASAL3 Expression
    About this image

    RASAL3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RASAL3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.136979
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RASAL3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for RASAL3 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rasal31 , 5 RAS protein activator like 31, 5 80.17(n)1
    80.7(a)1
      17 (17.55 cM)5
    3204841  NM_178785.31  NP_848900.21 
     323906595 
    chicken
    (Gallus gallus)
    Aves RASAL36
    RAS protein activator like 3
    43(a)
    1 ↔ 1
    JH375234.1(33879-47252)
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    30(a)
    many ↔ many
    2(79715660-79790730)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia rasal31 RAS protein activator like 3 50.33(n)
    43.42(a)
      100488943  XM_002935409.2  XP_002935455.2 
    zebrafish
    (Danio rerio)
    Actinopterygii rasal36
    RAS protein activator like 3
    31(a)
    1 ↔ 1
    6(9306393-9325605) ENSDARG00000089933
    fruit fly
    (Drosophila melanogaster)
    Insecta CG426846
    --
    14(a)
    1 → many
    X(17604178-17645718)
    worm
    (Caenorhabditis elegans)
    Secernentea gap-26
    Protein GAP-2, isoform b (gap-2) mRNA, complete cd...
    20(a)
    1 → many
    X(9472469-9516435) WBGene00001516
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes BUD26
    GTPase activating factor for Rsr1p/Bud1p required ...
    14(a)
    1 → many
    XI(266145-269459) YKL092C


    ENSEMBL Gene Tree for RASAL3 (if available)
    TreeFam Gene Tree for RASAL3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RASAL3 gene
    SYNGAP12  DAB2IP2  RASA42  RASA12  RASA22  RASA4B2  RASAL22  RASA32  
    RASAL12  
    4 SIMAP similar genes for RASAL3 using alignment to 3 protein entries:     RASL3_HUMAN (see all proteins):
    FLJ00087    SYNGAP1    DAB2IP    RASAL2

    Find genes that share paralogs with RASAL3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RASAL3 (see all 343)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs772754681,2
    C--15562784(+) AACCAG/AGAGAG 1 -- int12Minor allele frequency- A:0.02CSA WA 120
    rs1997616731,2
    C--15562792(+) GAGGGC/TTGCAC 1 -- int11Minor allele frequency- T:0.00EU 567
    rs2021580141,2
    --15562798(+) TGCACC/TGCAAC 1 -- int10--------
    rs2013035291,2
    C--15562833(+) TGCCCC/GAGGGC 1 -- int10--------
    rs1385031061,2
    C--15562844(+) TCAGAC/TGGCAA 1 -- int10--------
    rs2002333611,2
    --15562934(+) TCGGGA/GGATTG 1 -- int10--------
    rs23042011,2
    C--15563391(-) CCCCCC/TCCCCA 1 -- int1 trp30--------
    rs1141348791,2
    C--15563460(+) AGGGCT/CGGGCT 1 -- int11Minor allele frequency- C:0.01WA 118
    rs1997374551,2
    C--15563513(+) CGCAGC/TTGCTC 2 Q syn10--------
    rs2010425931,2
    C--15563529(+) GCTCCC/GTCAAG 2 T R mis10--------

    HapMap Linkage Disequilibrium report for RASAL3 (15562435 - 15575382 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for RASAL3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2551856CNV Deletion19546169
    dgv3746n71CNV Loss21882294
    nsv911133CNV Loss21882294
    dgv3747n71CNV Loss21882294
    nsv833765CNV Loss17160897
    nsv482216CNV Loss20164927

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RASAL3
    DNA2.0 Custom Variant and Variant Library Synthesis for RASAL3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RASAL3 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with RASAL3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    3. A human MAP kinase interactome. (PubMed id 20936779)1 Bandyopadhyay S....Ideker T. (Nat. Methods 2010)
    4. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)
    5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (Nature 2004)
    8. (PubMed id )2 

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 64926 HGNC: 26129 AceView: FLJ21438 Ensembl:ENSG00000105122 euGenes: HUgn64926
    ECgene: RASAL3 Kegg: 64926 H-InvDB: RASAL3

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RASAL3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RASAL3 gene:
    Search GeneIP for patents involving RASAL3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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