RASA4 Gene
protein-coding GIFtS: 54
GCID: GC07M102220
|
|
RAS p21 protein activator 4
| |
Aliases
for RASA4 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| RAS P21 Protein Activator 41 2 3 | | Calcium-Promoted Ras Inactivator2 3 | | CAPRI1 2 3 5 | | RasGAP-Activating-Like Protein 22 3 | | GAPL1 2 3 5 | | Ca2+-Promoted Ras Inactivator2 | | KIAA05381 3 5 | | Ras GTPase-Activating Protein 42 |
Export aliases for RASA4 gene to outside databasesPrevious GC identifers: GC07M101781 GC07M101782 GC07M101813 GC07M102001 GC07M102007 GC07M043952 |
Summaries
for RASA4 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for RASA4:
This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activatedprotein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in thetranslocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras isconverted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathwaysthat regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding differentisoforms have been found for this gene. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: RASL2_HUMAN, O43374Function: Ca(2+)-dependent Ras GTPase-activating protein, that switches off the Ras-MAPK pathway following a stimulusthat elevates intracellular calcium. Functions as an adaptor for Cdc42 and Rac1 during FcR-mediated phagocytosis
Gene Wiki entry for RASA4
|
Genomic Views
for RASA4 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007933.15 NT_079596.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RASA4 gene promoter:
NF-YA Lmo2 NF-YB c-Rel CBF-B CBF-A HOXA5 CP1A NF-Y CBF(2)
Other transcription factors
Search SABiosciences Chromatin IP Primers for RASA4
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RASA4 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q22 Ensembl cytogenetic band: 7q22.1 HGNC cytogenetic band: 7q22-q31.1RASA4 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07M102220: view genomic region
(about GC identifiers)
Start:
|
102,220,093 bp from pter |
End:
|
102,283,316 bp from pter |
Size:
|
63,224 bases |
Orientation:
|
minus strand |
1 alternative location:
| Chr7-,CRA_TCAG 101,580,464-101,617,574 |
|
Proteins
for RASA4 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RASL2_HUMAN, O43374 (See
protein sequence)Recommended Name: Ras GTPase-activating protein 4 Size: 803 amino acids; 90458 Da
Subcellular location: Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein. Note=Localized to the cytosol asa result of its lack of phosphoinositide binding activity. Upon agonist-stimulated calcium mobilization, utilizes theC2A and C2B domains to associate with the plasma membrane
Sequence caution: Sequence=AAB97935.2; Type=Erroneous gene model prediction; Sequence=AAP22345.1; Type=Erroneous genemodel prediction; Sequence=BAA25464.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: O60286 Q14CQ4 Q86UW3 Q96QU0Alternative splicing: 2 isoforms: O43374-1 O43374-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for RASA4: NX_O43374
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O43374
RASA4 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001073346.2 NP_008920.5
ENSEMBL proteins: ENSP00000262940 ENSP00000420352 ENSP00000412876 ENSP00000417395 ENSP00000428605 ENSP00000430337 ENSP00000430418 ENSP00000428732 ENSP00000428448 ENSP00000438250
Human Recombinant Protein Products for RASA4:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
RASA4 for ontologies About GeneDecksing
RASA4 Antibody Products:
Assay Products for RASA4: |
Protein
Domains /
Families
for RASA4 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RASA4 for domains About GeneDecksing
5/10 InterPro domains/families (see all 10):Graphical View of Domain Structure for InterPro Entry O43374ProtoNet protein and cluster: O43374 4 Blocks protein families: IPB000008 C2 domain IPB001562 Tec/Btk domain signature IPB001849 Pleckstrin-like IPB001936 Ras GTPase-activating protein
UniProtKB/Swiss-Prot: RASL2_HUMAN, O43374Domain: The PH domain does not bind phosphatidylinositol 4,5-bisphosphate or phosphatidylinositol 3,4,5-trisphosphate.This lack of binding activity is due to Leu-592, compared to Arg found in other family membersSimilarity: Contains 1 Btk-type zinc fingerSimilarity: Contains 2 C2 domainsSimilarity: Contains 1 PH domainSimilarity: Contains 1 Ras-GAP domain |
Function
for RASA4 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: RASL2_HUMAN, O43374Function: Ca(2+)-dependent Ras GTPase-activating protein, that switches off the Ras-MAPK pathway following a stimulusthat elevates intracellular calcium. Functions as an adaptor for Cdc42 and Rac1 during FcR-mediated phagocytosis Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
RASA4 for ontologies About GeneDecksing
Phenotypes:
2 GenomeRNAi human phenotypes for RASA4:
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Rasa4):
RASA4 for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Rasa4tm1Ywh for RASA4
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RASA4 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RASA4 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): RASA4 (NM_006989) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RASA4 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RASA4 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RASA4 |
|
Pathways & Interactions
for RASA4 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RASA4
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
5/17 Interacting proteins for RASA4 (O433742, 3 ENSP000002629404) via UniProtKB, MINT, STRING, and/or I2D (see all 17)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0032320 | positive regulation of Ras GTPase activity |
ISS | -- | | GO:0035556 | intracellular signal transduction |
IEA | -- | | GO:0043547 | positive regulation of GTPase activity |
-- | -- | | GO:0046580 | negative regulation of Ras protein signal transduction |
ISS | -- | | GO:0051056 | regulation of small GTPase mediated signal transduction |
-- | -- |
RASA4 for ontologies About GeneDecksing
|
Drugs & Compounds
for RASA4 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for RASA4
1 HMDB Compound for RASA4 About this table
Search CenterWatch for drugs/clinical trials and news about RASA4 / RASL2
|
Transcripts
for RASA4 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RASA4 gene (2 alternative transcripts): NM_001079877.2 NM_006989.5 Unigene Cluster for RASA4: RAS p21 protein activator 4 Hs.696339 [show with all ESTs]Unigene Representative Sequence: NM_00698918/19 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19): ENST00000262940(uc011kky.2 uc011kkz.2 uc011kla.2 uc010lig.3 uc003vae.3 uc003vaf.3 uc011klb.2)
ENST00000518350 ENST00000461209 ENST00000449970 ENST00000522223 ENST00000462172(uc011kld.1)
ENST00000523568(uc011klc.1 uc010lih.2) ENST00000521822 ENST00000521397
ENST00000520577 ENST00000519539 ENST00000518123 ENST00000522801 ENST00000519878
ENST00000520042 ENST00000521076 ENST00000522443 ENST00000521892
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RASA4 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RASA4 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): RASA4 (NM_006989) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RASA4 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RASA4 |
Additional cDNA sequence: AB011110.2 AK026441.1 AK093486.1 AK301666.1 AK308653.1 AK310176.1 AK315928.1 BC110873.1 BC113663.1 BC143584.1 BC143585.1 24/30 DOTS entries (see all 30): DT.450079 DT.109323 DT.95298751 DT.121040347 DT.100804097 DT.100683608 DT.97818880 DT.100804093 DT.92439249 DT.121040311 DT.92439252 DT.97862049 DT.100768827 DT.102839826 DT.121040397 DT.97862047 DT.100804088 DT.101963045 DT.102840216 DT.121040267 DT.121040468 DT.121040927 DT.121041009 DT.121041135 7 AceView cDNA sequences: BQ896855 AI378796 BM698658 BU731028 BE549500 BI910228 NM_006989
GeneLoc Exon Structure
5/14 Alternative Splicing Database (ASD) splice patterns (SP) for RASA4 (see all 14) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18a | · | 18b | ^ | 19a | · | 19b | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24a | · | 24b | · | 24c |
|---|
|
| SP1: | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | |
| SP4: | - | | - | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for RASA4
|
Expression
for RASA4 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RASA4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCTGGCCGGA
About this image
See RASA4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RASA4
SOURCE GeneReport for Unigene cluster: Hs.696339
UniProtKB/Swiss-Prot: RASL2_HUMAN, O43374Tissue specificity: Widely expressed
SABiosciences Custom PCR Arrays for RASA4
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RASA4
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat RASA4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RASA4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RASA4 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RASA4 |
Orthologs
for RASA4 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for RASA4 gene from 2/10 species (see all 10) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
RASA41 |
RAS p21 protein activator 4 |
72.7(n)
67.34(a) |
|
417513 XM_415761.3 XP_415761.3 |
zebrafish
(Danio rerio) |
Actinopterygii |
rasa41 |
RAS p21 protein activator 4 |
64.45(n)
62.23(a) |
|
567599 NM_001099451.1 NP_001092921.1 |
ENSEMBL Gene Tree for RASA4 (if available)
TreeFam Gene Tree for RASA4 (if available) |
Paralogs
for RASA4 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RASA4 gene
- SYNGAP12 DAB2IP2 RASA12 RASAL32 RASA22 RASA4B2 RASA32 RASAL22
- RASAL12
9 SIMAP similar genes for RASA4 using alignment to 9 protein entries: RASL2_HUMAN (see all proteins):RASA4B PRKCB RASAL1 PRKCA PRKCG PCLO
RASA3 RASA2 SYT7
RASA4 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for RASA4
PGOHUM00000250860
|
Genomic Variants
for RASA4 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for RASA4 (102220093 - 102283316 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 24 variations for RASA4
15/23 CNVs (see all 23): 2105 22940 36591 36594 70020 36595 36588 36585 0618 4553 82122 0724 36593 36592 94763
1 Indel: 41005 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RASA4 |
|
Disorders
/ Diseases
for RASA4 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RASA4 for disorders About GeneDecksing
OMIM gene information: 607943
OMIM disorders: --
1  disease for RASA4: About MalaCardspleuropneumonia
Export disorders for RASA4 gene to outside databases
|
Publications
for RASA4 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RASA4 gene, integrated from 9 sources (see all 15):
(articles sorted by number of sources associating them with RASA4) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway. (PubMed id 11448776)1, 2, 3 Lockyer P.J.... Cullen P.J. (2001)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
- Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9628581)1, 2 Nagase T....Ohara O. (1998)
- Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
- Ca2+-dependent monomer and dimer formation switches C APRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities. (PubMed id 21460216)1 Dai Y....Lockyer P.J. (2011)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (2005)
- CAPRI and RASAL impose different modes of information processing on Ras due to contrasting temporal filtering of Ca2+. (PubMed id 16009725)1 Liu Q....Lockyer P.J. (2005)
|
External Searches for RASA4 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing RASA4 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RASA4 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing RASA4 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for RASA4 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for RASA4 gene:
Search GeneIP for patents involving RASA4
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RASA4 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for RASA4 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RASA4 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RASA4 | | | OriGene Protein Over-expression Lysate for RASA4 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RASA4 | | OriGene 3'-UTR Clone for RASA4 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RASA4 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RASA4 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for RASA4 | | OriGene Custom Protein Services for RASA4 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RASA4 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RASA4 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RASA4 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RASA4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RASA4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RASA4 |
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| | | | Search Tocris compounds for RASA4 |
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 | | | RASA4 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RASA4 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for RASA4 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RASA4 |
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