Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RARRES1 Gene

protein-coding   GIFtS: 53
GCID: GC03M158414

retinoic acid receptor responder (tazarotene induced) 1
 Explore 14 diseases affiliated with
RARRES1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for RARRES1    

Aliases
for RARRES1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Retinoic Acid Receptor Responder (Tazarotene Induced) 11 2
TIG11 2 3 5
Tazarotene-Induced Gene 1 Protein2 3
RAR-Responsive Protein TIG12 3
Retinoic Acid Receptor Responder Protein 12

External Ids:    HGNC: 98671   Entrez Gene: 59182   Ensembl: ENSG000001188497   OMIM: 6050905   UniProtKB: P497883   

Export aliases for RARRES1 gene to outside databases

Previous GC identifers: GC03M155675 GC03M159362 GC03M159696 GC03M159735 GC03M159897 GC03M155810


Summaries
for RARRES1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for RARRES1:
This gene was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The
expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this
gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG
island. Alternatively spliced transcript variant encoding distinct isoforms have been observed. (provided by RefSeq,
Jul 2008)

Gene Wiki entry for RARRES1


Genomic Views
for RARRES1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.1  NT_005612.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RARRES1 gene promoter:
         c-Fos   AP-1   GATA-3   FosB   c-Jun   GATA-1   GATA-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: RARRES1 promoter sequence
   Search SABiosciences Chromatin IP Primers for RARRES1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RARRES1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q25.32   Ensembl cytogenetic band:  3q25.32   HGNC cytogenetic band: 3q25.32

RARRES1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RARRES1 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M158414:  view genomic region     (about GC identifiers)

Start:
 158,414,681 bp from pter      End:
 158,450,485 bp from pter
Size:
 35,805 bases      Orientation:
 minus strand

Proteins
for RARRES1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: TIG1_HUMAN, P49788 (See protein sequence)
Recommended Name: Retinoic acid receptor responder protein 1  
Size: 294 amino acids; 33285 Da
Subcellular location: Membrane; Single-pass type II membrane protein (Potential)
Secondary accessions: Q8N1D7
Alternative splicing: 2 isoforms:  P49788-1   P49788-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RARRES1: NX_P49788

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P49788

    • RARRES1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_002879.2  NP_996846.1  

    ENSEMBL proteins: 
     ENSP00000237696   ENSP00000418556   ENSP00000418087  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: RARRES1
    OriGene Custom Protein Services for RARRES1 
    GenScript Custom Purified and Recombinant Proteins Services for RARRES1
    Novus Biologicals RARRES1 Proteins
    Novus Biologicals RARRES1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for RARRES1

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane IEA--


    RARRES1 for ontologies           About GeneDecksing



    RARRES1 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    R&D Systems Antibodies for RARRES1
    OriGene Antibodies (see all 8): RARRES1
    OriGene Custom Antibody Services for RARRES1 
    GenScript Custom Superior Antibodies Services for RARRES1
    Novus Biologicals RARRES1 Antibodies
    Search for Antibodies for RARRES1 at Abcam  
    Uscn Antibodies for RARRES1
    Search ThermoFisher Antibodies for RARRES1

    Assay Products for RARRES1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for RARRES1
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for RARRES1

    Protein Domains /
    Families
    for RARRES1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    RARRES1 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR027261 TAG1
     IPR009684 Prot_inh_latexin

    Graphical View of Domain Structure for InterPro Entry P49788

    ProtoNet protein and cluster: P49788

    1 Blocks protein family: IPB009684 Proteinase inhibitor I47

    UniProtKB/Swiss-Prot: TIG1_HUMAN, P49788
    Similarity: Belongs to the protease inhibitor I47 (latexin) family


    Function
    for RARRES1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: TIG1_HUMAN, P49788
    Induction: By tazarotene and by all the retinoic acid receptors tested

    miRNA
    Products:            		 OriGene 3'-UTR Clone (see all 2): RARRES1
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RARRES1
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate RARRES1:
    hsa-miR-2909 hsa-miR-548n
    SwitchGear 3'UTR luciferase reporter plasmid: RARRES1 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RARRES1 (see all 4)
    OriGene shRNA RFP: RARRES1
    OriGene siRNA: RARRES1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RARRES1

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for RARRES1

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RARRES1 (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RARRES1 (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): RARRES1 (NM_002888)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RARRES1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RARRES1 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for RARRES1
    Search LifeMap BioReagents cell lines for RARRES1

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RARRES1


    Pathways & Interactions
    for RARRES1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RARRES1

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008285negative regulation of cell proliferation TAS9270552


    RARRES1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for RARRES1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    RARRES1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RARRES1

    1 HMDB Compound for RARRES1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Retinoic acidRetinoate (see all 21)302-79-4--

    1 DrugBank Compound for RARRES1    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    TretinoinAll Trans Retinoic Acid (see all 5)302-79-4targetagonist15059893 15897880

    3 Novoseek chemical compound relationships for RARRES1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    retinoic acid 67.8 14 8601727 (2), 16128742 (2), 18288381 (1), 16741146 (1) (see all 9)
    retinoid 64.1 5 8601727 (3), 16128742 (1), 16426842 (1)
    cysteine 19.7 1 16741146 (1)

    Search CenterWatch for drugs/clinical trials and news about RARRES1 / TIG1 

    Transcripts
    for RARRES1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for RARRES1 gene (2 alternative transcripts): 
    NM_002888.2  NM_206963.1  

    Unigene Cluster for RARRES1:

    Retinoic acid receptor responder (tazarotene induced) 1
    Hs.131269  [show with all ESTs]
    Unigene Representative Sequence: NM_206963
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000237696(uc003fci.3) ENST00000462663 ENST00000479756(uc003fcj.3)
    ENST00000471444 ENST00000498640

    miRNA
    Products:             		 OriGene 3'-UTR Clone (see all 2): RARRES1
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RARRES1
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate RARRES1:
    hsa-miR-2909 hsa-miR-548n
    SwitchGear 3'UTR luciferase reporter plasmid: RARRES1 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RARRES1 (see all 4)
    OriGene shRNA RFP: RARRES1
    OriGene siRNA: RARRES1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RARRES1
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RARRES1 (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RARRES1 (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): RARRES1 (NM_002888)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RARRES1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RARRES1 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RARRES1
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RARRES1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RARRES1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RARRES1

    Additional cDNA sequence: 

    AK130079.1 BC029640.1 U27185.1 

    11 DOTS entries:

    DT.208924  DT.106912  DT.95169318  DT.86846998  DT.100780083  DT.91707270  DT.91747325  DT.100780084 
    DT.120841425  DT.95169316  DT.91717246 

    24/112 AceView cDNA sequences (see all 112):

    AW664482 AI370216 CD679131 BX355675 CD722507 BU686100 CD679306 BM985270 
    CB134830 CD677270 AA969462 CD679124 CB306162 NM_206963 CD678113 AW474961 
    BM906395 AI691044 CD678112 AI261360 BU683921 AA366172 CR595342 AA302722 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for RARRES1    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b · 4c ^ 5 ^ 6
    SP1:                                                        -               
    SP2:                                                                        
    SP3:                          -     -     -                                 
    SP4:                          -                                             


    ECgene alternative splicing isoforms for RARRES1

    Expression
    for RARRES1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RARRES1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTAAACAAAG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    RARRES1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    LimbZeugopodPrechondrocytic Mesenchymal CellsBone, Cartilage
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 2 LifeMap Cells 
    NameCategory
    PureStem™ endothelial progenitor RP1-MV2-18 (Embryonic Progenitor Cell)Endothelium
    PureStem™ progenitor EN27 (Embryonic Progenitor Cell)

    See RARRES1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RARRES1

    SOURCE GeneReport for Unigene cluster: Hs.131269
        SABiosciences Custom PCR Arrays for RARRES1
    Primer
    Products:    		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RARRES1
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RARRES1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RARRES1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RARRES1
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RARRES1

    Orthologs
    for RARRES1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for RARRES1 gene from 4/8 species (see all 8)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Rarres11 , 5 retinoic acid receptor responder (tazarotene induced) more1, 5 76.57(n)1
    73.55(a)1    		   3 (30.99 cM)5
    1092221  NM_001164763.11  NP_001158235.11 
     674789725 
    chicken
    (Gallus gallus)    		 Aves RARRES11 retinoic acid receptor responder (tazarotene induced) more 53.13(n)
    36.4(a)    		   395209  NM_204534.4  NP_989865.1 
    lizard
    (Anolis carolinensis)    		 Reptilia RARRES16
    		 --
    		 36(a)
    		 1 ↔ 1
    		 3(14104464-14110120)
    zebrafish
    (Danio rerio)    		 Actinopterygii lxn6
    		 latexin
    		 24(a)
    		 1 → many
    		 15(1177988-1195587)


    ENSEMBL Gene Tree for RARRES1 (if available)
    TreeFam Gene Tree for RARRES1 (if available) 

    Paralogs
    for RARRES1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RARRES1 gene
    LXN2  
    1 SIMAP similar gene for RARRES1 using alignment to 2 protein entries:     TIG1_HUMAN (see all proteins):
    LXN

    RARRES1 for paralogs           About GeneDecksing



    Genomic Variants
    for RARRES1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/668 NCBI SNPs in RARRES1 are shown (see all 668)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 3 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs98732961,2
    		C,F,H,--158414496(+) CAGAAC/ACTGGC 1 -- ds50016Minor allele frequency- A:0.07NS EA WA 540
    rs1893474151,2
    		--158414506(+) CTCAAA/GGTTTT 1 -- ds50010--------
    rs67933031,2
    		C,F,H,--158414507(+) TCAAGG/ATTTTT 1 -- ds500111Minor allele frequency- A:0.08NS EA NA WA CSA 1210
    rs1153320171,2
    		C,F,--158414517(+) TACACA/GCCGAC 1 -- ds50011Minor allele frequency- G:0.02WA 118
    rs10122871,2
    		C,H--158414634(-) ACAGTA/TTGTAC 1 -- ds50015Minor allele frequency- T:0.00MN NS EA 600
    rs1488701911,2
    		--158414650(+) CCTTTA/GTAAAT 1 -- ds50010--------
    rs1435753541,2
    		--158414710(+) AATATG/TTAATA 1 -- ds50010--------
    rs168293091,2
    		C,F,H,--158414757(+) TTTGCA/GGACAG 1 -- ds50018Minor allele frequency- G:0.04NA NS EA WA 680
    rs117182691,2
    		H--158414996(+) AACAGG/TTAATT 1 -- ut310--------
    rs1414538521,2
    		--158415154(+) CAGTT-/AAAAAA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for RARRES1 (158414681 - 158450485 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for RARRES1
         1 CNV: 39348

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RARRES1
    DNA2.0 Custom Variant and Variant Library Synthesis for RARRES1

    Disorders / Diseases
    for RARRES1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    RARRES1 for disorders           About GeneDecksing

    OMIM gene information: 605090    OMIM disorders: --

    14 diseases for RARRES1:    About MalaCards
    prostate cancer    retinol binding protein    prostatitis    ovarian endometriosis
    squamous cell carcinoma    endometriosis    colon cancer    gastric cancer
    nasopharyngitis    psoriasis    prostate carcinoma    carcinoma
    schizophrenia    adenocarcinoma

    1 Novoseek disease relationship for RARRES1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tumors 24.1 10 11929948 (3), 15698574 (2), 16134180 (1), 20021617 (1) (see all 6)

    Human Genome Epidemiology (HuGE) Navigator: RARRES1 (1 document)

    Export disorders for RARRES1 gene to outside databases

    Publications
    for RARRES1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RARRES1 gene, integrated from 9 sources (see all 29):
    (articles sorted by number of sources associating them with RARRES1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Tazarotene-induced gene 1 (TIG1), a novel retinoic acid receptor- responsive gene in skin. (PubMed id 8601727)1, 2, 3, 9 Nagpal S....Chandraratna R.A.S. (1996)
    2. Hypermethylation and silencing of the putative tumor suppressor Tazarotene-induced gene 1 in human cancers. (PubMed id 15059893)1, 7 Youssef E.M....Issa J.P. (2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Molecular mechanisms of tazarotene action in psoriasis. (PubMed id 9270552)1, 3 Duvic M....Chandraratna R.A. (1997)
    5. Tazarotene-induced gene 1 (TIG1) expression in prostate carcinomas and its relationship to tumorigenicity. (PubMed id 11929948)1, 9 Jing C....Ke Y. (2002)
    6. DNA methylation of genes linked to retinoid signaling in squamous cell carcinoma of the esophagus: DNA methylation of CRBP1 and TIG1 is associated with tumor stage. (PubMed id 16128742)1, 9 Mizuiri H....Yasui W. (2005)
    7. Involvement of tazarotene-induced gene 1 in prolifera tion and differentiation of human adipose tissue-derived mesenchymal stem cells . (PubMed id 19250291)1, 9 Ohnishi S....Nagaya N. (2009)
    8. DNA methylation of genes linked with retinoid signaling in gastric carcinoma: expression of the retinoid acid receptor beta, cellular retinol-binding protein 1, and tazarotene-induced gene 1 genes is associated with DNA methylation. (PubMed id 16134180)1, 9 Shutoh M....Yasui W. (2005)
    9. Epigenetic repression of RARRES1 is mediated by methyl ation of a proximal promoter and a loss of CTCF binding. (PubMed id 22615834)1 Peng Z....Lin H.J. (2012)
    10. Tumor suppressor RARRES1 interacts with cytoplasmic c arboxypeptidase AGBL2 to regulate the I+-tubulin tyrosination cycle. (PubMed id 21303978)1 Sahab Z.J....Byers S.W. (2011)

    External Searches for RARRES1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing RARRES1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 5918 HGNC: 9867 AceView: RARRES1 Ensembl:ENSG00000118849 euGenes: HUgn5918
    ECgene: RARRES1 H-InvDB: RARRES1

    Other Databases showing RARRES1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing RARRES1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RARRES1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RARRES1 Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for RARRES1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for RARRES1 gene:
    Search GeneIP for patents involving RARRES1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for RARRES1 gene

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Antibodies for RARRES1 (RARRES1)   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     OriGene Antibodies for RARRES1   OriGene shRNA RFP for RARRES1  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RARRES1   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RARRES1  
     OriGene Protein Over-expression Lysate for RARRES1   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for RARRES1   OriGene 3'-UTR Clone for RARRES1  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RARRES1   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RARRES1  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for RARRES1   OriGene Custom Protein Services for RARRES1  
     OriGene Custom Immunoassay Development  

         		 
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RARRES1
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RARRES1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RARRES1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RARRES1
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RARRES1
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RARRES1
     GenScript Custom Purified and Recombinant Proteins Services for RARRES1 GenScript cDNA clones with any tag delivered in your preferred vector for RARRES1
     GenScript Custom Assay Services for RARRES1 GenScript Custom Superior Antibodies Services for RARRES1
     GenScript Custom overexpressing Cell Line Services for RARRES1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in RARRES1 promoter
     Search Chromatin IP Primers for RARRES1
     RT2 qPCR Primer Assay in human, mouse, rat RARRES1
     Search GNC Networks for RARRES1
     SABiosciences Custom PCR Arrays for RARRES1
     Search Tocris compounds for RARRES1
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     RARRES1 antibodies
     RARRES1 proteins
     RARRES1 lysates
     Search for Antibodies for RARRES1 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for RARRES1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     RARRES1 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for RARRES1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RARRES1
     SwitchGear 3'UTR luciferase reporter plasmids for RARRES1
     SwitchGear Promoter luciferase reporter plasmids for RARRES1
     Search ThermoFisher Antibodies for RARRES1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RARRES1
           
    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 

    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Copyright © 1996-2013 , Weizmann Institute of Science. All Rights Reserved.
    Hot genes      Disease genes      RARRES1 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4