RAPH1 Gene
protein-coding GIFtS: 50
GCID: GC02M204259
|
|
Ras association (RalGDS/AF-6) and pleckstrin homology domains...(Previous names: amyotrophic lateral sclerosis 2 (juvenile) chromosome region,...)
(Previous symbols: ALS2CR9, ALS2CR18)
| |
Aliases
for RAPH1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ras Association (RalGDS/AF-6) And Pleckstrin Homology Domains 11 2 | | PREL-22 3 | | ALS2CR181 2 3 | | PREL22 3 | | ALS2CR91 2 3 | | RMO12 3 | | Amyotrophic Lateral Sclerosis 2 (Juvenile) Chromosome Region, Candidate 91 2 | | RalGDS/AF-62 | | KIAA16811 3 | | Amyotrophic Lateral Sclerosis 2 (Juvenile) Chromosome Region, Candidate 182 | | Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 18 Protein2 3 | | Lamellipodin3 | | Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 9 Protein2 3 | | Ras-Associated And Pleckstrin Homology Domains-Containing Protein 12 | | Proline-Rich EVH1 Ligand 22 3 | | Lamellipodin3 | | LPD2 3 | | Protein RMO13 |
Export aliases for RAPH1 gene to outside databasesPrevious GC identifers: GC02M204503 GC02M204501 GC02M204124 GC02M204006 GC02M196146 |
Summaries
for RAPH1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: RAPH1_HUMAN, Q70E73Function: Mediator of localized membrane signals. Implicated in the regulation of lamellipodial dynamics. Negativelyregulates cell adhesion
Gene Wiki entry for RAPH1
|
Genomic Views
for RAPH1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_005403.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RAPH1 gene promoter:
GR GR-alpha Pax-4a Cdc5 NF-AT Roaz
Other transcription factors
Search SABiosciences Chromatin IP Primers for RAPH1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RAPH1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q33 Ensembl cytogenetic band: 2q33.2 HGNC cytogenetic band: 2q33RAPH1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02M204259: view genomic region
(about GC identifiers)
Start:
|
204,259,068 bp from pter |
End:
|
204,400,133 bp from pter |
Size:
|
141,066 bases |
Orientation:
|
minus strand |
|
Proteins
for RAPH1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RAPH1_HUMAN, Q70E73 (See
protein sequence)Recommended Name: Ras-associated and pleckstrin homology domains-containing protein 1 Size: 1250 amino acids; 135256 Da
Subunit: Interacts with EVL and VASP and targets them to the leading edge
Subcellular location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium.Cell projection, filopodium. Cytoplasm, cytoskeleton. Note=Recruited to the membrane, via the PH domain, by thephosphoinositide, PI(3,4)P2. Colocalizes with ENAH/VASP at the tips of lamellipodia and filopodia. Also colocalizeswith the pathogens, Vaccinia and Enteropathogenic E.coli (EPEC) at the interface between the pathogen and their actin
2 PDB 3D structures from  and Proteopedia  for RAPH1:4GMV (3D)
4GN1 (3D)
Secondary accessions: Q96Q37 Q9C0I2Alternative splicing: 9 isoforms: Q70E73-10 Q70E73-2 Q70E73-3 Q70E73-4 Q70E73-5 Q70E73-6 Q70E73-7 Q70E73-8 Q70E73-9 Explore the universe of human proteins at neXtProt for RAPH1: NX_Q70E73
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q70E73
RAPH1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_976241.1 NP_998754.1
ENSEMBL proteins: ENSP00000392854 ENSP00000316543 ENSP00000363617 ENSP00000311293 ENSP00000411138 ENSP00000390578 ENSP00000397751 ENSP00000406662 ENSP00000415364 ENSP00000396711 ENSP00000394454 ENSP00000414430 ENSP00000412241 ENSP00000363613 ENSP00000363612
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
RAPH1 for ontologies About GeneDecksing
RAPH1 Antibody Products:
Assay Products for RAPH1: |
Protein
Domains /
Families
for RAPH1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RAPH1 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q70E73ProtoNet protein and cluster: Q70E73 1 Blocks protein family: IPB001849 Pleckstrin-like
UniProtKB/Swiss-Prot: RAPH1_HUMAN, Q70E73Similarity: Belongs to the MRL familySimilarity: Contains 1 PH domainSimilarity: Contains 1 Ras-associating domain |
Function
for RAPH1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: RAPH1_HUMAN, Q70E73Function: Mediator of localized membrane signals. Implicated in the regulation of lamellipodial dynamics. Negativelyregulates cell adhesionInduction: Reduced expression in metastatic osteosarcomas compared to primary osteosarcoma tumors. Down-regulated inboth breast (43% of tissue samples) and ovarian (25% of tissue samples) cancers
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RAPH1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RAPH1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): RAPH1 (NM_213589) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RAPH1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAPH1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAPH1 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005543 | phospholipid binding |
IEA | -- |
RAPH1 for ontologies About GeneDecksing
|
Pathways & Interactions
for RAPH1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RAPH1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 6)
5/6 Interacting proteins for RAPH1 (Q70E733 ENSP000003165434) via UniProtKB, MINT, STRING, and/or I2D (see all 6)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
RAPH1 for ontologies About GeneDecksing
|
Drugs & Compounds
for RAPH1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
RAPH1 for compounds About GeneDecksing
 Browse Tocris compounds for RAPH1
1 Novoseek chemical compound relationship for RAPH1 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| lipid |
0 |
5 |
9499429 (3), 11210182 (2) |
Search CenterWatch for drugs/clinical trials and news about RAPH1
|
Transcripts
for RAPH1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RAPH1 gene (3 alternative transcripts): NM_025252.3 NM_203365.2 NM_213589.1 Unigene Cluster for RAPH1: Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 Hs.471162 [show with all ESTs]Unigene Representative Sequence: NM_21358916 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000457812 ENST00000319170(uc002vad.3) ENST00000374493 ENST00000308091(uc002vae.3)
ENST00000439222 ENST00000419464 ENST00000423104 ENST00000453034(uc002vaf.3)
ENST00000432342 ENST00000418114 ENST00000413201 ENST00000428637 ENST00000420371
ENST00000465669 ENST00000374489 ENST00000374488
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RAPH1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RAPH1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): RAPH1 (NM_213589) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RAPH1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAPH1 |
Additional cDNA sequence: AB051468.1 AB053311.1 AB053320.1 AF086189.1 AJ584699.1 AK022729.1 AK095976.1 AK096270.1 AY494951.1 AY523977.1 AY523978.1 10 DOTS entries: DT.423011 DT.91662876 DT.95159381 DT.451636 DT.92055135 DT.99977502 DT.109461 DT.95079003 DT.70105441 DT.97763976 24/199 AceView cDNA sequences (see all 199): BX470737 AA987614 BF445392 AI458522 AL135425 AI033234 BF475299 NM_213589 BF111090 NM_025252 AI217860 AI133724 AK095976 CB163652 AA421057 NM_203365 CN482583 CB161412 AI207967 BG222922 AA370625 F09058 CB162970 CK904997
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for RAPH1 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16a | · | 16b | ^ | 17 | ^ | 18 |
|---|
|
| SP1: | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | |
| SP2: | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | - | | | | - | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | - | | - | | | | |
| SP4: | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for RAPH1
|
Expression
for RAPH1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RAPH1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAGAGGGAAG
About this image
See RAPH1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RAPH1
SOURCE GeneReport for Unigene cluster: Hs.471162
UniProtKB/Swiss-Prot: RAPH1_HUMAN, Q70E73Tissue specificity: Isoform RMO1-RAPH1 is ubiquitously expressed with highest levels in brain, heart, ovary anddeveloping embryo. Isoform RMO1 is widely expressed with highest levels in liver. Low expression in B-cells
SABiosciences Custom PCR Arrays for RAPH1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RAPH1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RAPH1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RAPH1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RAPH1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAPH1 |
Orthologs
for RAPH1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for RAPH1 gene from 6/17 species (see all 17) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
RAPH11 |
Ras association (RalGDS/AF-6) and pleckstrin homology more |
77.63(n)
85.04(a) |
|
424107 XM_421961.3 XP_421961.3 |
lizard
(Anolis carolinensis) |
Reptilia |
RAPH16 |
-- |
81(a) |
1 ↔ 1 |
GL343208.1(3044269-3092814) |
African clawed frog
(Xenopus laevis) |
Amphibia |
BU910789.12 |
-- |
73.9(n) |
|
BU910789.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
raph11 |
Ras association (RalGDS/AF-6) and pleckstrin homology more |
63.91(n)
66.3(a) |
|
557435 XM_680506.3 XP_685598.3 |
fruit fly
(Drosophila melanogaster) |
Insecta |
pico6 |
pico |
18(a) |
1 → many |
X(19724248-19746092) |
worm
(Caenorhabditis elegans) |
Secernentea |
mig-106 |
Abnormal cell migration protein 10 |
22(a) |
1 → many |
III(8279037-8305761) |
ENSEMBL Gene Tree for RAPH1 (if available)
TreeFam Gene Tree for RAPH1 (if available) |
Paralogs
for RAPH1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RAPH1 gene
- APBB1IP2 GRB72 GRB102 GRB142
3 SIMAP similar genes for RAPH1 using alignment to 5 protein entries: RAPH1_HUMAN (see all proteins):GRB10 APBB1IP GRB14
RAPH1 for paralogs About GeneDecksing
|
Genomic Variants
for RAPH1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for RAPH1 (204259068 - 204400133 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 10 variations for RAPH1
8 CNVs: 78944 78942 78943 90228 68223 78941 90226 90227
2 Indels: 78945 90229 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RAPH1 |
|
Disorders
/ Diseases
for RAPH1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RAPH1 for disorders About GeneDecksing
OMIM gene information: 609035
OMIM disorders: --
12  diseases for RAPH1: About MalaCardsamyotrophic lateral sclerosis lateral sclerosis hypertriglyceridemia breast-ovarian cancer
ovarian cancer osteosarcoma vaccinia pharyngitis
breast cancer tuberculosis neuronitis mycobacterium tuberculosis
2 Novoseek disease relationships for RAPH1 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| hypertriglyceridemia |
43.9 |
2 |
11210182 (1), 9499429 (1) |
| fatty liver |
41.2 |
2 |
11210182 (1), 9499429 (1) |
Human Genome Epidemiology (HuGE) Navigator: RAPH1 (1 document)
Export disorders for RAPH1 gene to outside databases
|
Publications
for RAPH1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RAPH1 gene, integrated from 9 sources (see all 34):
(articles sorted by number of sources associating them with RAPH1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Lamellipodin, an Ena/VASP ligand, is implicated in the regulation of lamellipodial dynamics. (PubMed id 15469845)1, 2, 9 Krause M.... Gertler F.B. (2004)
- Altered expression and deletion of RMO1 in osteosarcoma. (PubMed id 15609301)1, 2, 9 Eppert K....Andrulis I.L. (2005)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
- Systematic identification and molecular characterization of genes differentially expressed in breast and ovarian cancer. (PubMed id 15586368)1, 2 Dahl E.... Niederacher D. (2005)
- A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2. (PubMed id 11586298)1, 2 Hadano S....Ikeda J.-E. (2001)
- Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2 Nagase T.... Ohara O. (2000)
- c-Abl, Lamellipodin, and Ena/VASP proteins cooperate in dorsal ruffling of fibroblasts and axonal morphogenesis. (PubMed id 20417104)2, 9 Michael M....Krause M. (2010)
- Drosophila pico and its mammalian ortholog lamellipodin activate serum response factor and promote cell proliferation. (PubMed id 19000833)1, 9 Lyulcheva E....Bennett D. (2008)
- Lamellipodin proline rich peptides associated with native plasma butyrylcholinesterase tetramers. (PubMed id 18076380)1, 9 Li H....Lockridge O. (2008)
- A phosphatidylinositol lipids system, lamellipodin, an d Ena/VASP regulate dynamic morphology of multipolar migrating cells in the deve loping cerebral cortex. (PubMed id 22915108)1 Yoshinaga S....Nakajima K. (2012)
|
External Searches for RAPH1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing RAPH1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RAPH1 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing RAPH1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for RAPH1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for RAPH1 gene:
Search GeneIP for patents involving RAPH1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RAPH1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for RAPH1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RAPH1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RAPH1 | | | OriGene Protein Over-expression Lysate for RAPH1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RAPH1 | | OriGene 3'-UTR Clone for RAPH1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RAPH1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RAPH1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for RAPH1 | | OriGene Custom Protein Services for RAPH1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RAPH1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RAPH1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RAPH1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RAPH1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RAPH1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RAPH1 |
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| | | | Search Tocris compounds for RAPH1 |
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 | | | RAPH1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAPH1 |
|  |  |  | | | | Search ThermoFisher Antibodies for RAPH1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAPH1 |
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