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RAPGEFL1 Gene

protein-coding   GIFtS: 45
GCID: GC17P038333

Rap Guanine Nucleotide Exchange Factor (GEF)-Like 1

(Previous name: RAP guanine-nucleotide-exchange factor (GEF)-like 1)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Rap Guanine Nucleotide Exchange Factor (GEF)-Like 11 2
Link Guanine Nucleotide Exchange Factor II1 2 3
RAP Guanine-Nucleotide-Exchange Factor (GEF)-Like 11 2
Link GEFII2 3
Link-GEFII2
Rap Guanine Nucleotide Exchange Factor-Like 12

External Ids:    HGNC: 174281   Entrez Gene: 511952   Ensembl: ENSG000001083527   UniProtKB: Q9UHV53   

Export aliases for RAPGEFL1 gene to outside databases

Previous GC identifers: GC17P038710 GC17P035588 GC17P034127


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RAPGEFL1 Gene:
RAPGEFL1 (Rap guanine nucleotide exchange factor (GEF)-like 1) is a protein-coding gene. GO annotations related to this gene include guanyl-nucleotide exchange factor activity. An important paralog of this gene is RAPGEF2.

UniProtKB/Swiss-Prot: RPGFL_HUMAN, Q9UHV5
Function: Probable guanine nucleotide exchange factor (GEF)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NT_010783.16  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RAPGEFL1 gene promoter:
         Egr-3   TBP   p53   Pax-5   ATF-2   Brachyury   p300   Lmo2   CRE-BP1   SEF-1 (1)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRAPGEFL1 promoter sequence
   Search Chromatin IP Primers for RAPGEFL1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RAPGEFL1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.1   Ensembl cytogenetic band:  17q21.1   HGNC cytogenetic band: 17q21.2

RAPGEFL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAPGEFL1 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P038333:  view genomic region     (about GC identifiers)

Start:
38,333,263 bp from pter      End:
38,351,908 bp from pter
Size:
18,646 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RPGFL_HUMAN, Q9UHV5 (See protein sequence)
Recommended Name: Rap guanine nucleotide exchange factor-like 1  
Size: 662 amino acids; 73265 Da
Sequence caution: Sequence=BAG36274.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for RAPGEFL1:
2DHZ (3D)    
Alternative splicing: 3 isoforms:  Q9UHV5-1   Q9UHV5-2   Q9UHV5-3   

Explore the universe of human proteins at neXtProt for RAPGEFL1: NX_Q9UHV5

Explore proteomics data for RAPGEFL1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RAPGEFL1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_057423.1  
    ENSEMBL proteins: 
     ENSP00000394530   ENSP00000440226   ENSP00000438631   ENSP00000264644   ENSP00000440006  
     ENSP00000444646   ENSP00000441059   ENSP00000408322  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR008937 Ras_GEF
     IPR023578 Ras_GEF_dom
     IPR001895 RasGRF_CDC25

    Graphical View of Domain Structure for InterPro Entry Q9UHV5

    ProtoNet protein and cluster: Q9UHV5

    1 Blocks protein domain: IPB001895 Guanine-nucleotide dissociation stimulator CDC25

    UniProtKB/Swiss-Prot: RPGFL_HUMAN, Q9UHV5
    Similarity: Contains 1 Ras-GEF domain


    Find genes that share domains with RAPGEFL1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RPGFL_HUMAN, Q9UHV5
    Function: Probable guanine nucleotide exchange factor (GEF)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005057receptor signaling protein activity ----
    GO:0005085guanyl-nucleotide exchange factor activity IEA--
         
    Find genes that share ontologies with RAPGEFL1           About GenesLikeMe


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Rapgefl1):
     immune system 

    Find genes that share phenotypes with RAPGEFL1           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RAPGEFL1
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RAPGEFL1
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    miRNA
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    miRTarBase miRNAs that target RAPGEFL1:
    hsa-mir-30c-5p (MIRT047947), hsa-mir-296-3p (MIRT038353), hsa-let-7c-5p (MIRT051841)

    Block miRNA regulation of human, mouse, rat RAPGEFL1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RAPGEFL1 (see all 72):
    hsa-miR-642a hsa-miR-520e hsa-miR-520f hsa-miR-376b hsa-miR-300 hsa-miR-15a hsa-miR-1224-3p hsa-miR-106a
    SwitchGear 3'UTR luciferase reporter plasmidRAPGEFL1 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAPGEFL1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus2
    cytoskeleton1
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular IEA--
    GO:0016020membrane TAS9582122

    Find genes that share ontologies with RAPGEFL1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RAPGEFL1
    Interactions:

        Search GeneGlobe Interaction Network for RAPGEFL1

    1 Interacting protein for RAPGEFL1 (Q9UHV53) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MLH1P406923I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction ----
    GO:0007186G-protein coupled receptor signaling pathway TAS9582122
    GO:0007264small GTPase mediated signal transduction IEA--
    GO:0007399nervous system development TAS9789079
    GO:0043087regulation of GTPase activity TAS9582122

    Find genes that share ontologies with RAPGEFL1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RAPGEFL1 (RPGFL)

    3 HMDB Compounds for RAPGEFL1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine diphosphate5'-GDP (see all 10)146-91-8--
    Guanosine monophosphate5'-GMP (see all 14)85-32-5--
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RAPGEFL1 gene: 
    NM_016339.3  

    Unigene Cluster for RAPGEFL1:

    Rap guanine nucleotide exchange factor (GEF)-like 1
    Hs.632254  [show with all ESTs]
    Unigene Representative Sequence: NM_016339
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000456989 ENST00000543876 ENST00000544503 ENST00000264644 ENST00000538884
    ENST00000540388 ENST00000541245 ENST00000538981 ENST00000545893 ENST00000469209
    ENST00000496032 ENST00000436615(uc010cwu.1 uc010wfd.1)
    miRNA
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    Block miRNA regulation of human, mouse, rat RAPGEFL1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RAPGEFL1 (see all 72):
    hsa-miR-642a hsa-miR-520e hsa-miR-520f hsa-miR-376b hsa-miR-300 hsa-miR-15a hsa-miR-1224-3p hsa-miR-106a
    SwitchGear 3'UTR luciferase reporter plasmidRAPGEFL1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat RAPGEFL1
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    GenScript: all cDNA clones in your preferred vector: RAPGEFL1 (NM_016339)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RAPGEFL1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAPGEFL1
    Primer
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    OriGene qPCR primer pairs and template standards for RAPGEFL1
    OriGene qSTAR qPCR primer pairs in human, mouse for RAPGEFL1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RAPGEFL1
      QuantiTect SYBR Green Assays in human, mouse, rat RAPGEFL1
      QuantiFast Probe-based Assays in human, mouse, rat RAPGEFL1

    Additional mRNA sequence: 

    AF117946.1 AK294642.1 AK304160.1 AK313492.1 BC029956.1 BC115374.1 BC115375.1 BC128521.1 
    U78518.1 

    8 DOTS entries:

    DT.310340  DT.120974143  DT.95361213  DT.86847942  DT.95348413  DT.75197439  DT.97792250  DT.92425229 

    Selected AceView cDNA sequences (see all 126):

    BC029956 BU858185 BU620959 AA064784 CB850973 CD673750 BG057081 AI202634 
    CB241983 BU620139 T04994 AI700328 AL133709 AI702874 BM757171 AW139646 
    BM677918 CD627796 AA774924 BM910044 AA309020 AA868888 BM019813 AA731508 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RAPGEFL1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGTATTGTAC
    RAPGEFL1 Expression
    About this image

    RAPGEFL1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RAPGEFL1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.632254
        Custom PCR Arrays for RAPGEFL1
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for RAPGEFL1 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rapgefl11 , 5 Rap guanine nucleotide exchange factor (GEF)-like 11, 5 89.04(n)1
    96.49(a)1
      11 (62.70 cM)5
    2684801  NM_001080925.11  NP_001074394.11 
     988367855 
    lizard
    (Anolis carolinensis)
    Reptilia RAPGEFL16
    Rap guanine nucleotide exchange factor (GEF)-like ...
    78(a)
    1 ↔ 1
    6(69545041-69581271)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia rapgefl11 Rap guanine nucleotide exchange factor (GEF)-like 1 68.57(n)
    73.63(a)
      100145761  NM_001127132.1  NP_001120604.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1001494971 rap guanine nucleotide exchange factor-like 1-like 63.33(n)
    61.11(a)
      100149497  XM_001920985.3  XP_001921020.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta Epac6
    Epac
    16(a)
    1 → many
    2R(2647220-2686446)
    worm
    (Caenorhabditis elegans)
    Secernentea epac-16
    Protein EPAC-1 (epac-1) mRNA, complete cds
    13(a)
    1 → many
    III(10189218-10195399) WBGene00004255


    ENSEMBL Gene Tree for RAPGEFL1 (if available)
    TreeFam Gene Tree for RAPGEFL1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RAPGEFL1 gene
    RAPGEF22  RAPGEF62  RASGEF1A2  RAPGEF32  RAPGEF42  RASGEF1C2  ENSG000002732172  RASGEF1B2  
    RAPGEF52  
    5 SIMAP similar genes for RAPGEFL1 using alignment to 6 protein entries:     RPGFL_HUMAN (see all proteins):
    RAPGEF4    Nbla00496    RAPGEF3    DKFZp781H1715    RAPGEF5

    Find genes that share paralogs with RAPGEFL1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RAPGEFL1 (see all 393)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs781276101,2
    --38332289(+) CAGTCC/TGTTTT 1 -- us2k10--------
    rs1175068481,2
    C,F--38332328(+) CCCCAA/GTTCGC 1 -- us2k11Minor allele frequency- G:0.01NA 120
    rs1494560451,2
    --38332482(+) AACCCA/GTTCCA 1 -- us2k10--------
    rs1459250401,2
    --38332592(+) TGTGCA/GCTGTC 1 -- us2k10--------
    rs1923651981,2
    --38332911(+) TCCTCC/TCCCAC 1 -- us2k10--------
    rs99119361,2
    C,F,H--38333032(+) TGTACA/GCTTGG 1 -- us2k112Minor allele frequency- G:0.09NS EA NA CSA WA 1311
    rs774441591,2
    F--38333134(+) CTTGTG/ACTCCT 1 -- us2k11Minor allele frequency- A:0.01NA 120
    rs286473391,2
    C,F,H--38333172(+) CTCCTC/TACCCC 1 -- us2k1 tfbs3 trp32Minor allele frequency- T:0.02NS NA 96
    rs1476748111,2
    --38333178(+) ACCCC-/AG    
       CTAGA
    CCTGC
    1 -- us2k10--------
    rs1881320761,2
    --38333291(+) GATGGC/GCACCG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for RAPGEFL1 (38333263 - 38351908 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for RAPGEFL1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv833444CNV Loss17160897
    nsv525796CNV Gain19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RAPGEFL1
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RAPGEFL1 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with RAPGEFL1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    2. Cytoskeletal scaffolding proteins interact with Lynch-Syndrome associated mismatch repair protein MLH1. (PubMed id 20706999)1 Brieger A....Trojan J. (Proteomics 2010)
    3. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)2 Zody M.C.... Nusbaum C. (Nature 2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    7. RasGRP, a Ras guanyl nucleotide- releasing protein with calcium- and diacylglycerol-binding motifs. (PubMed id 9582122)1 Ebinu J.O....Stone J.C. (Science 1998)
    8. A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia. (PubMed id 9789079)1 Kawasaki H.... Graybiel A.M. (Proc. Natl. Acad. Sci. U.S.A. 1998)
    9. (PubMed id )2 

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51195 HGNC: 17428 AceView: RAPGEFL1 Ensembl:ENSG00000108352 euGenes: HUgn51195
    ECgene: RAPGEFL1 H-InvDB: RAPGEFL1

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RAPGEFL1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RAPGEFL1 gene:
    Search GeneIP for patents involving RAPGEFL1

    GeneCards and IP:
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