RAPGEF2 Gene
protein-coding GIFtS: 56
GCID: GC04P160025
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|
Rap guanine nucleotide exchange factor (GEF) 2(Previous name: PDZ domain containing guanine nucleotide exchange factor...)
(Previous symbol: PDZGEF1)
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Aliases
for RAPGEF2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Rap Guanine Nucleotide Exchange Factor (GEF) 21 2 | | NRap GEP2 3 | | PDZ-GEF11 2 3 | | PDZ Domain-Containing Guanine Nucleotide Exchange Factor 12 3 | | PDZGEF11 2 3 | | DKFZP586O14221 | | RA-GEF1 2 3 | | CNrasGEF2 | | PDZ Domain Containing Guanine Nucleotide Exchange Factor (GEF) 11 2 | | RA(Ras/Rap1A-Associating)-GEF1 | | KIAA03131 3 | | Rap-GEP2 | | Neural RAP Guanine Nucleotide Exchange Protein2 3 | | Rap Guanine Nucleotide Exchange Factor 22 | | NRAPGEP2 3 | | |
Export aliases for RAPGEF2 gene to outside databasesPrevious GC identifers: GC04P160767 GC04P160546 GC04P160244 GC04P160409 GC04P160188 GC04P155939 |
Summaries
for RAPGEF2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for RAPGEF2:
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulatedswitches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs),such as RAPGEF2, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state andare the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 (PubMed 10934204)).(suppliedby OMIM, Mar 2008)
UniProtKB/Swiss-Prot: RPGF2_HUMAN, Q9Y4G8Function: Guanine nucleotide exchange factor (GEF) for Rap1A, Rap1B and Rap2B GTPases. Does not interact with cAMP orcGMP
Gene Wiki entry for RAPGEF2
|
Genomic Views
for RAPGEF2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_016354.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RAPGEF2 gene promoter:
C/EBPbeta HOXA3 ATF-2 Lmo2 Cdc5 RORalpha1 SRY FOXC1 Nkx6-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for RAPGEF2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RAPGEF2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4q32.1 Ensembl cytogenetic band: 4q32.1 HGNC cytogenetic band: 4q32.1RAPGEF2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04P160025: view genomic region
(about GC identifiers)
Start:
|
160,025,330 bp from pter |
End:
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160,281,321 bp from pter |
Size:
|
255,992 bases |
Orientation:
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plus strand |
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Proteins
for RAPGEF2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RPGF2_HUMAN, Q9Y4G8 (See
protein sequence)Recommended Name: Rap guanine nucleotide exchange factor 2 Size: 1499 amino acids; 167417 Da
Subunit: Interacts with MAGI2
Subcellular location: Cell membrane (By similarity). Note=Associated with the synaptic plasma membrane (By similarity)
Sequence caution: Sequence=BAA20772.2; Type=Erroneous initiation;
Secondary accessions: D3DP27Explore the universe of human proteins at neXtProt for RAPGEF2: NX_Q9Y4G8
Post-translational modifications:
Phosphorylation by PLK2 promotes its activity (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y4G8
RAPGEF2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_055062.1
ENSEMBL proteins: ENSP00000422707 ENSP00000421602 ENSP00000421740 ENSP00000264431 ENSP00000422361 ENSP00000421624 ENSP00000422098 ENSP00000421083 ENSP00000427334
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
RAPGEF2 for ontologies About GeneDecksing
RAPGEF2 Antibody Products:
Assay Products for RAPGEF2: |
Protein
Domains /
Families
for RAPGEF2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RAPGEF2 for domains About GeneDecksing
5/9 InterPro domains/families (see all 9):Graphical View of Domain Structure for InterPro Entry Q9Y4G8ProtoNet protein and cluster: Q9Y4G8 4 Blocks protein families: IPB000159 RA domain IPB000595 Cyclic nucleotide-binding domain IPB001478 PDZ/DHR/GLGF domain IPB001895 Guanine-nucleotide dissociation stimulator CDC25
UniProtKB/Swiss-Prot: RPGF2_HUMAN, Q9Y4G8Similarity: Contains 1 cyclic nucleotide-binding domainSimilarity: Contains 1 N-terminal Ras-GEF domainSimilarity: Contains 1 PDZ (DHR) domainSimilarity: Contains 1 Ras-associating domainSimilarity: Contains 1 Ras-GEF domain |
Function
for RAPGEF2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: RPGF2_HUMAN, Q9Y4G8Function: Guanine nucleotide exchange factor (GEF) for Rap1A, Rap1B and Rap2B GTPases. Does not interact with cAMP orcGMP
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RAPGEF2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RAPGEF2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAPGEF2 |
Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7): About this table
RAPGEF2 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for RAPGEF2:
Animal Models:
Mouse knock-outs for RAPGEF2: Rapgef2tm1.1Tkat Rapgef2tm1.2Hous
12 MGI mutant phenotypes (inferred from 4 alleles ) (MGI details for Rapgef2):
RAPGEF2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for RAPGEF2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Development_A2B receptor- action via G-protein alpha s | | | 2 | G-protein signaling_G-Protein alpha-i signaling cascades | | | 3 | G-protein signaling Rap1A regulation pathway | | | 4 | G-protein signaling K-RAS regulation pathway | | | 5 | G-protein signaling_RhoA regulation pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/7 EMD Millipore Pathways for RAPGEF2 (see all 7)
5/7  GeneGo (Thomson Reuters) Pathways for RAPGEF2 (see all 7)
1 
Kegg Pathway (Kegg details for RAPGEF2):
RAPGEF2 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RAPGEF2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 22)
5/66 Interacting proteins for RAPGEF2 (Q9Y4G82, 3 ENSP000002644314) via UniProtKB, MINT, STRING, and/or I2D (see all 66)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table
RAPGEF2 for ontologies About GeneDecksing
|
Drugs & Compounds
for RAPGEF2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
RAPGEF2 for compounds About GeneDecksing
 Browse Tocris compounds for RAPGEF2
10/847 HMDB Compounds for RAPGEF2 (see all 847) About this table
2 Novoseek chemical compound relationships for RAPGEF2 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| gdp |
62.7 |
1 |
11168587 (1) |
| gtp |
51.7 |
1 |
11168587 (1) |
Search CenterWatch for drugs/clinical trials and news about RAPGEF2 / RPGF2
|
Transcripts
for RAPGEF2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RAPGEF2 gene: NM_014247.2 Unigene Cluster for RAPGEF2: Rap guanine nucleotide exchange factor (GEF) 2 Hs.113912 [show with all ESTs]Unigene Representative Sequence: NM_01424713 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000505478 ENST00000504604 ENST00000503328 ENST00000511336 ENST00000510510
ENST00000264431(uc003iqg.4) ENST00000514565 ENST00000513816 ENST00000512056
ENST00000502485 ENST00000510253 ENST00000505026 ENST00000509891
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RAPGEF2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RAPGEF2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: RAPGEF2 (NM_014247) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RAPGEF2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAPGEF2 |
Additional cDNA sequence: AB002311.1 AF070570.1 AK294459.1 BC110355.1 BC117321.1 BX640769.1 11 DOTS entries: DT.318505 DT.100782568 DT.92037359 DT.110285 DT.91912041 DT.75189664 DT.100680526 DT.100782566 DT.95373730 DT.100782572 DT.91741520 24/191 AceView cDNA sequences (see all 191): BG403618 AI092560 BQ017652 BX642629 CA867476 BF435298 BE644674 AA766231 AI469956 AA628277 BU620827 AA884263 CB530005 AI861871 CD674417 AA845840 CR621095 BU739348 BM714697 AF070570 CA438264 BF435817 CD743235 BE552426
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for RAPGEF2 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16a | · | 16b | ^ | 17 | ^ | 18a | · | 18b | ^ | 19 | ^ | 20a | · | 20b | ^ | 21a | · | 21b | ^ | 22a | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 22b | · | 22c | ^ | 23a | · | 23b | ^ | 24 | ^ | 25 |
|---|
|
| SP1: | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | |
ECgene alternative splicing isoforms for RAPGEF2
|
Expression
for RAPGEF2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RAPGEF2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGCATATAGA
About this image
See RAPGEF2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RAPGEF2
SOURCE GeneReport for Unigene cluster: Hs.113912
UniProtKB/Swiss-Prot: RPGF2_HUMAN, Q9Y4G8Tissue specificity: Highest expression levels in brain. Lower expression levels in heart, kidney, lung, and placenta
SABiosciences Custom PCR Arrays for RAPGEF2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RAPGEF2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RAPGEF2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RAPGEF2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RAPGEF2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAPGEF2 |
Orthologs
for RAPGEF2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for RAPGEF2 gene from 5/23 species (see all 23) About this table
ENSEMBL Gene Tree for RAPGEF2 (if available)
TreeFam Gene Tree for RAPGEF2 (if available) |
Paralogs
for RAPGEF2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RAPGEF2 gene
- RAPGEFL12 RAPGEF62 RASGEF1A2 RAPGEF32 RASGEF1C2 RAPGEF42 RASGEF1B2 RAPGEF52
7 SIMAP similar genes for RAPGEF2 using alignment to 10 protein entries: RPGF2_HUMAN (see all proteins):DKFZp586O1422 PDZGEF1 KIA001LB RAPGEF6 FNIP1 PDZD11
RAPGEF3
RAPGEF2 for paralogs About GeneDecksing
|
Genomic Variants
for RAPGEF2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RAPGEF2 |
|
Disorders
/ Diseases
for RAPGEF2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 RAPGEF2 for disorders About MalaCards
RAPGEF2 for disorders About GeneDecksing
OMIM gene information: 609530
OMIM disorders: --
Export disorders for RAPGEF2 gene to outside databases
|
Publications
for RAPGEF2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RAPGEF2 gene, integrated from 9 sources (see all 32):
(articles sorted by number of sources associating them with RAPGEF2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase. Regulation of MR-GEF by M-Ras-GTP interaction. (PubMed id 10934204)1, 2, 3, 9 Rebhun J.F.... Quilliam L.A. (2000)
- Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9205841)1, 2, 3 Nagase T.... Ohara O. (1997)
- PDZ-GEF1, a guanine nucleotide exchange factor specific for Rap1 and Rap2. (PubMed id 10608883)1, 2 de Rooij J....Bos J.L. (1999)
- nRap GEP: a novel neural GDP/GTP exchange protein for rap1 small G protein that interacts with synaptic scaffolding molecule (S-SCAM). (PubMed id 10548487)1, 2 Ohtsuka T.... Takai Y. (1999)
- RA-GEF, a novel Rap1A guanine nucleotide exchange factor containing a Ras/Rap1A-associating domain, is conserved between nematode and humans. (PubMed id 10608844)1, 9 Liao Y....Kataoka T. (1999)
- A yeast two-hybrid screen reveals that osteopontin ass ociates with MAP1A and MAP1B in addition to other proteins linked to microtubule stability, apoptosis and protein degradation in the human brain. (PubMed id 22779921)1 Long P....Rose S. (2012)
- DNA methylation shows genome-wide association of NFIX, RAPGEF2 and MSRB3 with gestational age at birth. (PubMed id 22422452)1 Lee H....Fallin M.D. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Epac1 and PDZ-GEF cooperate in Rap1 mediated endothel ial junction control. (PubMed id 21840392)1 Pannekoek W.J....Bos J.L. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
|
External Searches for RAPGEF2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing RAPGEF2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RAPGEF2 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing RAPGEF2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for RAPGEF2 gene:
Search GeneIP for patents involving RAPGEF2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RAPGEF2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for RAPGEF2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RAPGEF2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RAPGEF2 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RAPGEF2 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RAPGEF2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RAPGEF2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for RAPGEF2 | | OriGene Custom Protein Services for RAPGEF2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RAPGEF2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RAPGEF2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RAPGEF2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RAPGEF2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RAPGEF2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RAPGEF2 |
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| | | | Search Tocris compounds for RAPGEF2 |
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 | | | RAPGEF2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAPGEF2 |
|  |  |  | | | | Search ThermoFisher Antibodies for RAPGEF2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAPGEF2 |
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