Aliases for RAP1GDS1 Gene
External Ids for RAP1GDS1 Gene
Previous GeneCards Identifiers for RAP1GDS1 Gene
The smg GDP dissociation stimulator (smgGDS) protein is a stimulatory GDP/GTP exchange protein with GTPase activity (Riess et al., 1993 [PubMed 8262526]).[supplied by OMIM, Feb 2010]
GeneCards Summary for RAP1GDS1 Gene
RAP1GDS1 (Rap1 GTPase-GDP Dissociation Stimulator 1) is a Protein Coding gene. Diseases associated with RAP1GDS1 include acute lymphocytic leukemia. Among its related pathways are Regulation of RAC1 activity and G-protein signaling_Regulation of RAC1 activity. GO annotations related to this gene include binding and proton-transporting ATPase activity, rotational mechanism.
UniProtKB/Swiss-Prot for RAP1GDS1 Gene
Stimulates GDP/GTP exchange reaction of a group of small GTP-binding proteins (G proteins) including Rap1a/Rap1b, RhoA, RhoB and KRas, by stimulating the dissociation of GDP from and the subsequent binding of GTP to each small G protein.