Free for academic non-profit institutions. Other users need a Commercial license

Aliases for RAP1BL Gene

Aliases for RAP1BL Gene

  • RAP1B, Member Of RAS Oncogene Family Pseudogene 3
  • Ras-Related Protein Rap-1b-Like Protein 3 5
  • Rap1B-Retro 3
  • HCG1757335 3
  • AC113404.1 5

External Ids for RAP1BL Gene

Previous GeneCards Identifiers for RAP1BL Gene

  • GC05M075465

Summaries for RAP1BL Gene

GeneCards Summary for RAP1BL Gene

RAP1BL (RAP1B, Member Of RAS Oncogene Family Pseudogene) is a Pseudogene. GO annotations related to this gene include GTP binding. An important paralog of this gene is RAP1B.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RAP1BL Gene

Genomics for RAP1BL Gene

Regulatory Elements for RAP1BL Gene

Enhancers for RAP1BL Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05G075335 1.2 ENCODE 11.8 +835.4 835415 7.8 MLX CREB3L1 DMAP1 FEZF1 YY1 ZNF143 ZNF263 SP3 NFYC TBX21 RAP1BL RPS26P26 ANKDD1B GCNT4 POLK POC5 GC05P075337 ENSG00000271815
GH05G076174 1.2 Ensembl ENCODE 0.7 -1.4 -1428 1.9 HDAC1 PKNOX1 ATF1 RAD21 ZBTB40 TCF12 GATA2 ZNF143 IKZF2 CREM SV2C LOC105379041 LOC100132039 SAP18P1 RAP1BL GC05M076242
GH05G076180 1.2 Ensembl ENCODE 0.4 -7.0 -7047 1.9 HDAC1 PKNOX1 ATF1 SIN3A ZNF766 GATA2 CBX5 FOS ETV6 IKZF2 SV2C LOC105379041 LOC100132039 SAP18P1 RAP1BL GC05M076242
GH05G076191 0.4 ENCODE 0.4 -18.2 -18177 1.6 SMARCA4 SV2C LOC105379041 LOC100132039 SAP18P1 RAP1BL GC05M076242
GH05G076198 0.5 ENCODE 0.3 -22.9 -22937 0.2 PKNOX1 PBX2 TAL1 LOC105379041 SV2C LOC100132039 SAP18P1 RAP1BL GC05M076242
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around RAP1BL on UCSC Golden Path with GeneCards custom track

Promoters for RAP1BL Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000182715 54 201 ZNF507

Genomic Location for RAP1BL Gene

Chromosome:
5
Start:
76,170,085 bp from pter
End:
76,174,354 bp from pter
Size:
4,270 bases
Orientation:
Minus strand

Genomic View for RAP1BL Gene

Genes around RAP1BL on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RAP1BL Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RAP1BL Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RAP1BL Gene

Proteins for RAP1BL Gene

  • Protein details for RAP1BL Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NIZ1-RP1BL_HUMAN
    Recommended name:
    Ras-related protein Rap-1b-like protein
    Protein Accession:
    A6NIZ1

    Protein attributes for RAP1BL Gene

    Size:
    184 amino acids
    Molecular mass:
    20925 Da
    Quaternary structure:
    • Interacts with SGSM1, SGSM2 and SGSM3.

neXtProt entry for RAP1BL Gene

Post-translational modifications for RAP1BL Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RAP1BL Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for RAP1BL Gene

Domains & Families for RAP1BL Gene

Protein Domains for RAP1BL Gene

Graphical View of Domain Structure for InterPro Entry

A6NIZ1

UniProtKB/Swiss-Prot:

RP1BL_HUMAN :
  • Belongs to the small GTPase superfamily. Ras family.
Family:
  • Belongs to the small GTPase superfamily. Ras family.
genes like me logo Genes that share domains with RAP1BL: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for RAP1BL Gene

Function for RAP1BL Gene

Molecular function for RAP1BL Gene

UniProtKB/Swiss-Prot EnzymeRegulation:
Activated by guanine nucleotide-exchange factor (GEF) EPAC2 in a cAMP-dependent manner.

Gene Ontology (GO) - Molecular Function for RAP1BL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003924 GTPase activity IEA --
GO:0005525 GTP binding IEA --
genes like me logo Genes that share ontologies with RAP1BL: view
genes like me logo Genes that share phenotypes with RAP1BL: view

Animal Model Products

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RAP1BL Gene

Localization for RAP1BL Gene

Subcellular locations from UniProtKB/Swiss-Prot for RAP1BL Gene

Cell membrane. Cytoplasm, cytosol. Note=May shuttle between plasma membrane and cytosol. {ECO:0000250}.

Gene Ontology (GO) - Cellular Components for RAP1BL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005737 cytoplasm IEA --
GO:0005829 cytosol IEA --
GO:0005886 plasma membrane IEA --
GO:0016020 membrane IEA --
genes like me logo Genes that share ontologies with RAP1BL: view

No data available for Subcellular locations from COMPARTMENTS for RAP1BL Gene

Pathways & Interactions for RAP1BL Gene

SuperPathways for RAP1BL Gene

No Data Available

Interacting Proteins for RAP1BL Gene

Selected Interacting proteins: A6NIZ1-RP1BL_HUMAN for RAP1BL Gene via IID

Gene Ontology (GO) - Biological Process for RAP1BL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007264 small GTPase mediated signal transduction IEA --
genes like me logo Genes that share ontologies with RAP1BL: view

No data available for Pathways by source and SIGNOR curated interactions for RAP1BL Gene

Drugs & Compounds for RAP1BL Gene

No Compound Related Data Available

Transcripts for RAP1BL Gene

mRNA/cDNA for RAP1BL Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RAP1BL Gene

No ASD Table

Relevant External Links for RAP1BL Gene

GeneLoc Exon Structure for
RAP1BL

Expression for RAP1BL Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RAP1BL Gene

genes like me logo Genes that share expression patterns with RAP1BL: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RAP1BL Gene

Orthologs for RAP1BL Gene

Evolution for RAP1BL Gene

ENSEMBL:
Gene Tree for RAP1BL (if available)
TreeFam:
Gene Tree for RAP1BL (if available)

No data available for Orthologs for RAP1BL Gene

Paralogs for RAP1BL Gene

Paralogs for RAP1BL Gene

genes like me logo Genes that share paralogs with RAP1BL: view

Variants for RAP1BL Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for RAP1BL Gene

Disorders for RAP1BL Gene

Relevant External Links for RAP1BL

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
RAP1BL

No disorders were found for RAP1BL Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RAP1BL Gene

Publications for RAP1BL Gene

  1. The DNA sequence and comparative analysis of human chromosome 5. (PMID: 15372022) Schmutz J. … Rubin E.M. (Nature 2004) 3 4 64
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  3. The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability. (PMID: 23398456) Bett J.S. … Hay R.T. (Biochem. J. 2013) 3 64
  4. Retrotransposition and mutation events yield Rap1 GTPases with differential signalling capacity. (PMID: 20170508) Zemojtel T. … Zwartkruis F.J. (BMC Evol. Biol. 2010) 3 64
  5. HRap1B-retro: a novel human processed rap1B gene blurs the picture? (PMID: 16307016) Zemojtel T. … Zwartkruis F.J. (Leukemia 2006) 3 64

Products for RAP1BL Gene

Sources for RAP1BL Gene

Content
Loading form....