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Aliases for RAP1BL Gene

Aliases for RAP1BL Gene

  • RAP1B, Member Of RAS Oncogene Family Pseudogene 3
  • Ras-Related Protein Rap-1b-Like Protein 3
  • Rap1B-Retro 3
  • HCG1757335 3

External Ids for RAP1BL Gene

Previous GeneCards Identifiers for RAP1BL Gene

  • GC05M075465

Summaries for RAP1BL Gene

GeneCards Summary for RAP1BL Gene

RAP1BL (RAP1B, Member Of RAS Oncogene Family Pseudogene) is a Pseudogene. GO annotations related to this gene include GTP binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RAP1BL Gene

Genomics for RAP1BL Gene

Regulatory Elements for RAP1BL Gene

Genomic Location for RAP1BL Gene

Chromosome:
5
Start:
76,170,085 bp from pter
End:
76,174,354 bp from pter
Size:
4,270 bases
Orientation:
Minus strand

Genomic View for RAP1BL Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for RAP1BL Gene

Proteins for RAP1BL Gene

  • Protein details for RAP1BL Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NIZ1-RP1BL_HUMAN
    Recommended name:
    Ras-related protein Rap-1b-like protein
    Protein Accession:
    A6NIZ1

    Protein attributes for RAP1BL Gene

    Size:
    184 amino acids
    Molecular mass:
    20925 Da
    Quaternary structure:
    • Interacts with SGSM1, SGSM2 and SGSM3.

neXtProt entry for RAP1BL Gene

Proteomics data for RAP1BL Gene at MOPED

Post-translational modifications for RAP1BL Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RAP1BL Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for RAP1BL Gene

Domains & Families for RAP1BL Gene

Protein Domains for RAP1BL Gene

Graphical View of Domain Structure for InterPro Entry

A6NIZ1

UniProtKB/Swiss-Prot:

RP1BL_HUMAN :
  • Belongs to the small GTPase superfamily. Ras family.
Family:
  • Belongs to the small GTPase superfamily. Ras family.
genes like me logo Genes that share domains with RAP1BL: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for RAP1BL Gene

Function for RAP1BL Gene

Molecular function for RAP1BL Gene

UniProtKB/Swiss-Prot EnzymeRegulation:
Activated by guanine nucleotide-exchange factor (GEF) EPAC2 in a cAMP-dependent manner.

Gene Ontology (GO) - Molecular Function for RAP1BL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005525 GTP binding IEA --
genes like me logo Genes that share ontologies with RAP1BL: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RAP1BL Gene

Localization for RAP1BL Gene

Subcellular locations from UniProtKB/Swiss-Prot for RAP1BL Gene

Cell membrane. Cytoplasm, cytosol. Note=May shuttle between plasma membrane and cytosol. {ECO:0000250}.

Gene Ontology (GO) - Cellular Components for RAP1BL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005829 cytosol IEA --
GO:0005886 plasma membrane IEA --
GO:0016020 membrane --
genes like me logo Genes that share ontologies with RAP1BL: view

No data available for Subcellular locations from COMPARTMENTS for RAP1BL Gene

Pathways & Interactions for RAP1BL Gene

SuperPathways for RAP1BL Gene

No Data Available

Interacting Proteins for RAP1BL Gene

Gene Ontology (GO) - Biological Process for RAP1BL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction --
GO:0007264 small GTPase mediated signal transduction IEA --
GO:0015031 protein transport --
genes like me logo Genes that share ontologies with RAP1BL: view

No data available for Pathways by source and SIGNOR curated interactions for RAP1BL Gene

Drugs & Compounds for RAP1BL Gene

No Compound Related Data Available

Transcripts for RAP1BL Gene

mRNA/cDNA for RAP1BL Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RAP1BL Gene

No ASD Table

Relevant External Links for RAP1BL Gene

GeneLoc Exon Structure for
RAP1BL

Expression for RAP1BL Gene

mRNA expression in normal human tissues for RAP1BL Gene

genes like me logo Genes that share expression patterns with RAP1BL: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for RAP1BL Gene

Orthologs for RAP1BL Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for RAP1BL Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Gm9392 16
Species with no ortholog for RAP1BL:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RAP1BL Gene

ENSEMBL:
Gene Tree for RAP1BL (if available)
TreeFam:
Gene Tree for RAP1BL (if available)

Paralogs for RAP1BL Gene

No data available for Paralogs for RAP1BL Gene

Variants for RAP1BL Gene

Relevant External Links for RAP1BL Gene

HapMap Linkage Disequilibrium report
RAP1BL

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RAP1BL Gene

Disorders for RAP1BL Gene

genes like me logo Genes that share disorders with RAP1BL: view

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RAP1BL Gene

Publications for RAP1BL Gene

  1. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  2. A systems wide mass spectrometric based linear motif screen to identify dominant in-vivo interacting proteins for the ubiquitin ligase MDM2. (PMID: 24583282) Nicholson J. … Hupp T.R. (Cell. Signal. 2014) 67
  3. The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability. (PMID: 23398456) Bett J.S. … Hay R.T. (Biochem. J. 2013) 67
  4. Retrotransposition and mutation events yield Rap1 GTPases with differential signalling capacity. (PMID: 20170508) Zemojtel T. … Zwartkruis F.J. (BMC Evol. Biol. 2010) 67
  5. HRap1B-retro: a novel human processed rap1B gene blurs the picture? (PMID: 16307016) Zemojtel T. … Zwartkruis F.J. (Leukemia 2006) 67

Products for RAP1BL Gene

Sources for RAP1BL Gene

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