RANGAP1 Gene
protein-coding GIFtS : 65 GCID: GC22 M041641
Ran GTPase Activating Protein 1 segregation distorter homolog (Drosophila) )SD )
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Aliasesfor RANGAP1 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
10 fRNAdb ,
12 H-InvDB ,
13 NCBI ,
14 NONCODE ,
and/or 15 RNAdb )About This Section Aliases Ran GTPase Activating Protein 1 1 2 Ran GTPase-Activating Protein 12 SD1 2 3 Segregation Distorter Homolog2 Segregation Distorter Homolog (Drosophila)1 Segregation Distortion2 Fug12 KIAA18353 RANGAP2 RanGAP13
Export aliases for RANGAP1 gene to outside databases Previous GC identifers: GC22M038256 GC22M039884 GC22M039966 GC22M024606
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Summariesfor RANGAP1 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for RANGAP1 Gene: This gene encodes a protein that associates with the nuclear pore complex and participates in the regulation of nuclear transport. The encoded protein interacts with Ras-related nuclear protein 1 (RAN) and regulates guanosine triphosphate (GTP)-binding and exchange. Alternative splicing results in multiple transcript variants. (provided by RefSeq, Jul 2013) GeneCards Summary for RANGAP1 Gene: RANGAP1 (Ran GTPase activating protein 1) is a protein-coding gene. Diseases associated with RANGAP1 include herpes simplex multiple sclerosis related super-pathways are Mitotic Anaphase and Mitotic Prometaphase . GO annotations related to this gene include Ran GTPase activator activity and protein binding . UniProtKB/Swiss-Prot: RAGP1_HUMAN, P46060 Function : GTPase activator for the nuclear Ras-related regulatory protein Ran, converting it to the putatively inactiveGDP-bound state Gene Wiki entry for RANGAP1 Gene
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Genomic Viewsfor RANGAP1 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 73) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000022.10 NT_011520.12 NC_018933.2 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the RANGAP1 gene promoter:AhR CREB p53 AP-1 deltaCREB ATF-2 c-Jun Other transcription factors Search SABiosciences Chromatin IP Primers for RANGAP1 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 22q13 Ensembl cytogenetic band: 22q13.2 HGNC cytogenetic band: 22q13 RANGAP1 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 22 GeneLoc Exon Structure
GeneLoc location for GC22M041641: view genomic region
(about GC identifiers )
Start: 41,641,615 bp from pter End:
41,682,255 bp from pter
Size: 40,641 bases Orientation:
minus strand
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Proteinsfor RANGAP1 gene
(According to
UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE 1 MOPED ,
2 PaxDb , and 3 MAXQB
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Cloud-Clone Corp. ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Cloud-Clone Corp. ,
Ontologies according to Gene
Ontology Consortium 01 Oct 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
LSBio ,
Abcam , and/or
Cloud-Clone Corp. )
About This Section UniProtKB/Swiss-Prot: RAGP1_HUMAN, P46060 See
protein sequence )Recommended Name: Size : 587 amino acids; 63542 DaSubunit : Homodimer. Forms a tight complex in association with RANBP2/NUP358 and UBE2I/UBC9, the ubiquitin-conjugatingenzyme E2. Interacts with UBE2I; the interaction conjugates SUMO1 to RANGAP1, and subsequently stabilizes interactions of sumoylated RANGAP1 with RANBP2/NUP358. The SUMO1/RANGAP1/UBC9/NUP358 complex associates with nuclear pore complexes. Interacts with TRAF6
Subcellular location : Cytoplasm. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Chromosome,centromere, kinetochore (By similarity). Cytoplasm, cytoskeleton, spindle pole (By similarity). Note=Cytoplasmic during interphase. Targeted to the nuclear rim after sumoylation. During mitosis, associates with mitotic spindles. Association with kinetochores appears soon after nuclear envelope breakdown and persists until late anaphase. Mitotic location also requires sumoylation
Sequence caution : Sequence=BAB47464.1; Type=Erroneous initiation;6/12 PDB 3D structures from (see all 12 ):1Z5S (3D) 2GRN (3D) 2GRO (3D) 2GRP (3D) 2GRQ (3D) 2GRR (3D) Secondary accessions : Q96JJ2Explore the universe of human proteins at neXtProt for RANGAP1: NX_P46060 Explore proteomics data for RANGAP1 at MOPED Post-translational modifications:
UniProtKB: Phosphorylated occurs before nuclear envelope breakdown and continues throughout mitosis. Phosphorylated by the M-phase kinase cyclin B/Cdk1, in vitro. Differential timimg of dephosphorylation occurs during phases of mitosis. The phosphorylated form remains associated with RANBP2/NUP358 and the SUMO E2-conjugating enzyme, UBC9, on nuclear pore complex (NPC) diassembly and during mitosis
UniProtKB: Sumoylated with SUMO1. Sumoylation is necessary for targeting to the nuclear envelope (NE), and for association with mitotic spindles and kinetochores during mitosis. Also required for interaction with RANBP2 and is mediated by UBC9
View modification sites using PhosphoSitePlus View neXtProt modification sites for NX_P46060 RANGAP1 Protein expression data from MOPED1 2 3 : About this image REFSEQ proteins (2 alternative transcripts): NP_001265580.1 NP_002874.1 ENSEMBL proteins: ENSP00000385866 ENSP00000348577 ENSP00000401470 ENSP00000393407 ENSP00000394787 ENSP00000408743 ENSP00000404842 ENSP00000385354 Reactome Protein details: P46060 Human Recombinant Protein Products for RANGAP1: Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8 ): About this table
About GeneDecksing RANGAP1 Antibody Products: Assay Products for RANGAP1:
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Protein
Domains /for RANGAP1 gene (According to HGNC , IUPHAR , InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section 2 InterPro protein domains :
Graphical View of Domain Structure for InterPro Entry P46060 ProtoNet protein and cluster: P46060
1 Blocks protein domain : IPB001611 UniProtKB/Swiss-Prot: RAGP1_HUMAN, P46060 Similarity : Belongs to the RNA1 familySimilarity : Contains 6 LRR (leucine-rich) repeatsAbout GeneDecksing
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Functionfor RANGAP1 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene .)
About This Section Molecular Function: UniProtKB/Swiss-Prot Summary: RAGP1_HUMAN, P46060 Function : GTPase activator for the nuclear Ras-related regulatory protein Ran, converting it to the putatively inactiveGDP-bound state
Genatlas biochemistry entry for RANGAP1 Ran GTPase activating protein 1,homolog of yeast Rna1p,component of the nuclear pore complex,highly concentrated at its cytoplasmic periphery,conjugating with UBL1 in a ATP dependent fashion,then associating with RANBP2. Involved in mRNA processing and transport Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view) : About this table
About GeneDecksing Phenotypes: 3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Rangap1) :About GeneDecksing Animal Models: In Situ AssayAdvanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RANGAP1
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Pathways & Interactionsfor RANGAP1 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Sino Biological ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene) .
About This Section SuperPaths for RANGAP1 About (see all 10 ) See pathways by source SuperPath Contained pathways About 1 M Phase 2 Resolution of Sister Chromatid Cohesion 3 Cell Cycle 4 DNA damage Role of SUMO in p53 regulation 5 4-1BB Pathway
Pathways by source See SuperPaths Show all pathways 1 2 1 3 5/9 (see all 9 )1 (Kegg details for RANGAP1) :About GeneDecksing Interactions: SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RANGAP1 STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)5/903 Interacting proteins for RANGAP1 (P46060 1 , 2 , 3 ENSP00000348577 4 via UniProtKB, MINT, STRING , and/or I2D (see all 903 )About this table Gene Ontology (GO): 4 biological process terms (GO ID links to tree view) : About this table
About GeneDecksing
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Drugs & Compoundsfor RANGAP1 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
IUPHAR ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section About GeneDecksing Browse Tocris compounds for RANGAP1 (RAGP1) 2 Novoseek inferred chemical compound relationships for RANGAP1 gene About this table RANGAP1 / RAGP1
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Transcriptsfor RANGAP1 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , KenesGroup ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,EMD Millipore ,
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for RANGAP1 gene (2 alternative transcripts): NM_001278651.1 NM_002883.3 Unigene Cluster for RANGAP1:
Ran GTPase activating protein 1 Hs.183800 [show with all ESTs ] Unigene Representative Sequence: BC041396 8 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000405486 (uc003azt.3 ) ENST00000356244 (uc011aoz.2 uc003azu.3 )ENST00000455915 (uc003azs.3 ) ENST00000446258 ENST00000452543 ENST00000418067 ENST00000422838 ENST00000407260 Primer RANGAP1 human mouse SABiosciences RT2 qPCR Primer Assay in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat
Additional mRNA sequence: AK302222.1 AK303524.1 BC004990.1 BC014044.2 BC019676.1 BC041396.2 BC048990.1 CR456557.1 X82260.1
24/36 DOTS entries (see all 36 ): DT.100647773 DT.449648
DT.95154111 DT.100852871 DT.100647772 DT.100645443 DT.92451019 DT.100647777 DT.100709463 DT.100711353 DT.100768599 DT.92451021 DT.95272271 DT.100647775 DT.100839566 DT.100859349 DT.75170405 DT.100038346 DT.100637492 DT.100854577 DT.100864211 DT.92451015 DT.95272269 DT.100800164 24/323 AceView cDNA sequences (see all 323 ):
BM553423 CR599804 BM550926 BC012882 BQ641923 CN482804 AA709404 BC068590 BI828416 BM550690 BQ061240 CR456557 BQ893444 BM551464 BM542955 BC004990 BM553409 BC019676 BP430437 AA351030 BQ053784 BM810912 BU190935 BQ424384 GeneLoc Exon Structure 5/12 Alternative Splicing Database (ASD) splice patterns (SP) for RANGAP1 (see all 12 ) About this scheme ExUns: 1 ^ 2a · 2b · 2c · 2d · 2e ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d ^ 8a · 8b · 8c ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ SP1 : - - - - - - - SP2 : SP3 : - SP4 : - - - - - - SP5 : - - - - -
ExUns: 15a · 15b ^ 16a · 16b ^ 17a · 17b SP1 : SP2 : - - SP3 : - - SP4 : SP5 :
ECgene alternative splicing isoforms for RANGAP1
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Expression for RANGAP1 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section RANGAP1 expression in normal human tissues
(normalized intensities) RANGAP1 embryonic expression: see See probesets specificity/sensitivity at GeneAnnot About this image BioGPS 2/3 CGAP TAG: CTTTCCCCTTAbout this image
RANGAP1 expression in embryonic tissues and stem cells About this table LifeMap ,
the Embryonic Development and Stem Cells Database 5/28 selected tissues (see all 28 ) fully expand See RANGAP1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for RANGAP1 SOURCE GeneReport for Unigene cluster: Hs.183800 UniProtKB/Swiss-Prot: RAGP1_HUMAN, P46060 Tissue specificity : Highly expressed in brain, thymus and testisSABiosciences Expression via Pathway-Focused PCR Array including RANGAP1 : Multiple Sclerosis in human mouse rat
Primer RANGAP1 human mouse SABiosciences RT2 qPCR Primer Assay in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat In Situ Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RANGAP1
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Orthologsfor RANGAP1 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section Orthologs for RANGAP1 gene from 8/21 species (see all 21 ) About this table
Organism
Taxonomic
Gene
Description
Human
Orthology
Details
mouse Mammalia Rangap11 5
RAN GTPase activating protein 11, 5
86.09(n) 1 89.1(a) 1
15 (38.21 cM) 5 19387 1 NM_001146174.1 1 NP_001139646.1 1 81704248 5
chicken Aves RANGAP11
Ran GTPase activating protein 1
75.46(n) 82.24(a)
417997 NM_001006237.1 NP_001006237.1
lizard Reptilia RANGAP16
Uncharacterized protein
77(a)
1 ↔ 1
5(26276662-26299909)
African clawed frog Amphibia rangap1-prov2
RAN GTPase activating protein 1
75.33(n)
BC043982.1
zebrafish Actinopterygii Dr.265582
Danio rerio cDNA clone MGC66165 IMAGE5600717, complete more
73.92(n)
BC054654.1
fruit fly Insecta RanGap1
Ran GTPase activating protein
53.65(n) 42.29(a)
35223 NM_057364.3 NP_476712.1
worm Secernentea ran-23
RNA production/processing
51(a)
--
baker's yeast Saccharomycetes RNA1(YMR235C)4 1
GTPase activating protein (GAP) for Gsp1p, involved more 4 1
45.65(n) 1 33.61(a) 1
13(742735-741512) 4 855275 1, 4 NP_013962.1 1, 4
ENSEMBL Gene Tree for RANGAP1 (if available)TreeFam Gene Tree for RANGAP1 (if available)
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Paralogsfor RANGAP1 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section
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Genomic Variantsfor RANGAP1 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
4 UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical Chr 22 pos Sequence # AA Type More # Allele Pop Total More
HapMap Linkage Disequilibrium report for RANGAP1 (41641615 - 41682255 bp)
Structural Variations Database of Genomic Variants (DGV) 10/12 variations for RANGAP1 (see all 12 ): About this table SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human mouse rat
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Disorders
/ Diseasesfor RANGAP1 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database , Conferences by KenesGroup ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section About GeneDecksing OMIM gene information: 602362
OMIM disorders : --2 : About MalaCards herpes simplex multiple sclerosis Export disorders for RANGAP1 gene to outside databases
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Publicationsfor RANGAP1 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for RANGAP1 gene, integrated from 9 sources (see all 134 ):(articles sorted by number of sources associating them with RANGAP1) Utopia : connect your pdf to the dynamic
Human RanGTPase-activating protein RanGAP1 is a homologue of yeast Rna1p involved in mRNA processing and transport. (PubMed id 7878053) 1 , 2 , 3, 9(1995) Ubiquitous expression and testis-specific alternative polyadenylation of mRNA for the human Ran GTPase activator RanGAP1. (PubMed id 8973340) 1 , 2 , 9(1996) RanGAP1*SUMO1 is phosphorylated at the onset of mitosis and remains associated with RanBP2 upon NPC disassembly. (PubMed id 15037602) 1 , 2 , 9(2004) Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9- Nup358 complex. (PubMed id 15931224) 1 , 2 , 9(2005) Nuclear tumor necrosis factor receptor-associated factor 6 in lymphoid cells negatively regulates c-Myb-mediated transactivation through small ubiquitin-related modifier-1 modification. (PubMed id 18093978) 1 , 2 (2008) SUMO protease SENP1 induces isomerization of the scissile peptide bond. (PubMed id 17099698) 1 , 2 (2006) Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983) 1 , 2 (2006) A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802) 1 , 2 (2004) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 (2004) SUMO-1 targets RanGAP1 to kinetochores and mitotic spindles. (PubMed id 11854305) 1 , 2 (2002)
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External Searches for RANGAP1 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing RANGAP1 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
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Other Databases showing RANGAP1 gene
(According to HUGE )
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Specialized Databases showing RANGAP1 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description PharmGKB entry for RANGAP1 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for RANGAP1 gene: RANGAP1 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor RANGAP1 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Cloud-Clone Corp. , Thermo Fisher Scientific , LSBio , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RANGAP1 QIAGEN SeqTarget long-range PCR primers in human mouse rat QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RANGAP1
ThermoFisher Antibodies for RANGAP1
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat RANGAP1
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Aliases for RANGAP1
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Expression for RANGAP1
Function for RANGAP1
Genomic Views for RANGAP1
Intellectual Property for RANGAP1
Orthologs for RANGAP1
Paralogs for RANGAP1
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and Proteopedia 
for RANGAP1 (
GeneGo (Thomson Reuters) Pathway for RANGAP1
BioSystems Pathways for RANGAP1
Kegg Pathway 
Browse Tocris compounds for 
