RANBP3L Gene
protein-coding GIFtS: 39
GCID: GC05M036286
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RAN binding protein 3-like
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Aliases
for RANBP3L gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| RAN Binding Protein 3-Like1 2 | | FLJ254221 | | Ran-Binding Protein 3-Like2 |
Export aliases for RANBP3L gene to outside databases |
Summaries
for RANBP3L gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for RANBP3L gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_006576.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RANBP3L gene promoter:
HOXA9B HOXA9 Max1 Olf-1 Tal-1beta GATA-1 FOXO4 ITF-2 MRF-2 c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for RANBP3L
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RANBP3L |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5p13.2 Ensembl cytogenetic band: 5p13.2 HGNC cytogenetic band: 5p13.2RANBP3L Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05M036286: view genomic region
(about GC identifiers)
Start:
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36,248,536 bp from pter |
End:
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36,302,216 bp from pter |
Size:
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53,681 bases |
Orientation:
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minus strand |
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Proteins
for RANBP3L gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RNB3L_HUMAN, Q86VV4 (See
protein sequence)Recommended Name: Ran-binding protein 3-like Size: 465 amino acids; 52211 Da
Secondary accessions: B7Z866 E9PGP9 Q96LK2Alternative splicing: 3 isoforms: Q86VV4-1 Q86VV4-2 Q86VV4-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for RANBP3L: NX_Q86VV4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q86VV4
RANBP3L Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001154901.1 NP_659437.3
ENSEMBL proteins: ENSP00000296604 ENSP00000421853 ENSP00000421149 ENSP00000427147
Human Recombinant Protein Products for RANBP3L:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005622 | intracellular |
-- | -- |
RANBP3L for ontologies About GeneDecksing
RANBP3L Antibody Products:
Assay Products for RANBP3L: |
Protein
Domains /
Families
for RANBP3L gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RANBP3L for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q86VV4ProtoNet protein and cluster: Q86VV4 1 Blocks protein family: IPB000156 RanBP1 domain
UniProtKB/Swiss-Prot: RNB3L_HUMAN, Q86VV4Similarity: Contains 1 RanBD1 domain |
Function
for RANBP3L gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Phenotypes:
1 GenomeRNAi human phenotype for RANBP3L:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RANBP3L (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RANBP3L (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): RANBP3L (NM_145000) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RANBP3L | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RANBP3L |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RANBP3L |
|
Pathways & Interactions
for RANBP3L gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RANBP3L
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0046907 | intracellular transport |
IEA | -- |
RANBP3L for ontologies About GeneDecksing
|
Drugs & Compounds
for RANBP3L gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for RANBP3L
Search CenterWatch for drugs/clinical trials and news about RANBP3L / RNB3L
|
Transcripts
for RANBP3L gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RANBP3L gene (2 alternative transcripts): NM_001161429.1 NM_145000.3 Unigene Cluster for RANBP3L: RAN binding protein 3-like Hs.729817 [show with all ESTs]Unigene Representative Sequence: NM_0011614294 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000296604(uc011cow.2 uc003jkh.3) ENST00000502994 ENST00000515759
ENST00000505865
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RANBP3L (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RANBP3L (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): RANBP3L (NM_145000) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RANBP3L | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RANBP3L |
Additional cDNA sequence: AK058151.1 AK302947.1 BC017951.1 BC047660.1 3 DOTS entries: DT.75146840 DT.100748302 DT.97769066 18 AceView cDNA sequences: AK058151 NM_145000 CD106241 BC047660 AI675431 AL119068 BI546897 BG431086 BX115384 BC017951 BF674230 BG400002 AI783603 BM544392 BG699548 BG723201 BP369917 BF366785
GeneLoc Exon Structure
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Expression
for RANBP3L gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RANBP3L expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See RANBP3L Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RANBP3L
SOURCE GeneReport for Unigene cluster: Hs.729817
SABiosciences Custom PCR Arrays for RANBP3L
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RANBP3L
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RANBP3L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RANBP3L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RANBP3L | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RANBP3L |
Orthologs
for RANBP3L gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for RANBP3L gene from 9/23 species (see all 23) About this table
ENSEMBL Gene Tree for RANBP3L (if available)
TreeFam Gene Tree for RANBP3L (if available) |
Paralogs
for RANBP3L gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RANBP3L gene
- RANBP32
1 SIMAP similar gene for RANBP3L using alignment to 2 protein entries: RNB3L_HUMAN (see all proteins):RANBP3
RANBP3L for paralogs About GeneDecksing
|
Genomic Variants
for RANBP3L gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 5 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for RANBP3L (36248536 - 36302216 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for RANBP3L: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RANBP3L |
|
Disorders
/ Diseases
for RANBP3L gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for RANBP3L gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RANBP3L gene integrated from 9 sources:
(articles sorted by number of sources associating them with RANBP3L) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- The DNA sequence and comparative analysis of human chromosome 5. (PubMed id 15372022)2 Schmutz J.... Rubin E.M. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
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External Searches for RANBP3L gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing RANBP3L gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RANBP3L gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RANBP3L gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for RANBP3L | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for RANBP3L gene:
Search GeneIP for patents involving RANBP3L
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RANBP3L gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for RANBP3L | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RANBP3L | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RANBP3L | | | OriGene Protein Over-expression Lysate for RANBP3L | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RANBP3L | | OriGene 3'-UTR Clone for RANBP3L | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RANBP3L | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RANBP3L | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for RANBP3L | | OriGene Custom Protein Services for RANBP3L | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RANBP3L | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RANBP3L | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RANBP3L | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RANBP3L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RANBP3L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RANBP3L |
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 |  |  |  | |
| | | | Search Tocris compounds for RANBP3L |
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 | | | RANBP3L Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RANBP3L |
|  |  |  |  | | | | Search ThermoFisher Antibodies for RANBP3L |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RANBP3L |
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