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RANBP10 Gene

protein-coding   GIFtS: 52
GCID: GC16M067757

RAN Binding Protein 10

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RAN Binding Protein 101 2
KIAA14643 5
Ran-Binding Protein 102
RanBP103

External Ids:    HGNC: 292851   Entrez Gene: 576102   Ensembl: ENSG000001410847   OMIM: 6140315   UniProtKB: Q6VN203   

Export aliases for RANBP10 gene to outside databases

Previous GC identifers: GC16M067533 GC16M066314 GC16M053629


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RANBP10 Gene:
RANBP10 (RAN binding protein 10) is a protein-coding gene. GO annotations related to this gene include Ran guanyl-nucleotide exchange factor activity and beta-tubulin binding. An important paralog of this gene is SPRYD3.

UniProtKB/Swiss-Prot: RBP10_HUMAN, Q6VN20
Function: Acts as a guanine nucleotide exchange factor (GEF) for RAN GTPase (By similarity). May play an essential
role in hemostasis and in maintaining microtubule dynamics with respect to both platelet shape and function (By
similarity). May act as an adapter protein to couple membrane receptors to intracellular signaling pathways.
Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced
transactivation activity of NR3C1, but does not affect estrogen-induced transactivation. In contrast to RANBP9,
does not interact with Sos and does not activate the Ras pathway




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000016.9  NT_010498.16  NC_018927.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RANBP10 gene promoter:
         Nkx3-1   AML1a   Tal-1   MIF-1   E47   Egr-2   NRF-2   ATF   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRANBP10 promoter sequence
   Search Chromatin IP Primers for RANBP10

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RANBP10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q22.1   Ensembl cytogenetic band:  16q22.1   HGNC cytogenetic band: 16q22

RANBP10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RANBP10 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M067757:  view genomic region     (about GC identifiers)

Start:
67,757,005 bp from pter      End:
67,840,555 bp from pter
Size:
83,551 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RBP10_HUMAN, Q6VN20 (See protein sequence)
Recommended Name: Ran-binding protein 10  
Size: 620 amino acids; 67257 Da
Subunit: May form homodimers. Interacts with RAN and RANBP9. Interacts with the HGF receptor MET. Interacts with
AR. Interacts with TUBB1. May interact with TUBB5 (By similarity)
Sequence caution: Sequence=BAA95988.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A4FTY2 Q9P264

Explore the universe of human proteins at neXtProt for RANBP10: NX_Q6VN20

Explore proteomics data for RANBP10 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys293, Lys333
  • Modification sites at PhosphoSitePlus

  • See RANBP10 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_065901.1  
    ENSEMBL proteins: 
     ENSP00000316589   ENSP00000392808   ENSP00000473538   ENSP00000473396   ENSP00000473554  
     ENSP00000473395   ENSP00000416460   ENSP00000442249   ENSP00000410617  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    Selected InterPro protein domains (see all 10):
     IPR001870 B30.2/SPRY
     IPR027713 RANBP9/RANBP10/Ssh4
     IPR006594 LisH_dimerisation
     IPR013144 CRA_dom
     IPR024964 CTLH/CRA

    Graphical View of Domain Structure for InterPro Entry Q6VN20

    ProtoNet protein and cluster: Q6VN20

    2 Blocks protein domains:
    IPB006594 Lissencephaly type-1-like homology motif
    IPB006595 CTLH


    UniProtKB/Swiss-Prot: RBP10_HUMAN, Q6VN20
    Domain: The SPRY domain mediates the interaction with MET (By similarity)
    Similarity: Belongs to the RANBP9/10 family
    Similarity: Contains 1 B30.2/SPRY domain
    Similarity: Contains 1 CTLH domain
    Similarity: Contains 1 LisH domain


    Find genes that share domains with RANBP10           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RBP10_HUMAN, Q6VN20
    Function: Acts as a guanine nucleotide exchange factor (GEF) for RAN GTPase (By similarity). May play an essential
    role in hemostasis and in maintaining microtubule dynamics with respect to both platelet shape and function (By
    similarity). May act as an adapter protein to couple membrane receptors to intracellular signaling pathways.
    Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced
    transactivation activity of NR3C1, but does not affect estrogen-induced transactivation. In contrast to RANBP9,
    does not interact with Sos and does not activate the Ras pathway

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005087Ran guanyl-nucleotide exchange factor activity IEA--
    GO:0005515protein binding ----
    GO:0008536Ran GTPase binding IEA--
    GO:0048487beta-tubulin binding IEA--
         
    Find genes that share ontologies with RANBP10           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for RANBP10:
     Decreased Wnt reporter activit 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Ranbp10):
     cellular  hematopoietic system  homeostasis/metabolism 

    Find genes that share phenotypes with RANBP10           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RANBP10
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    miRTarBase miRNAs that target RANBP10:
    hsa-mir-186-5p (MIRT045170), hsa-mir-222-3p (MIRT046829), hsa-mir-15b-5p (MIRT046500), hsa-mir-124-3p (MIRT022988), hsa-mir-330-5p (MIRT038260), hsa-mir-615-3p (MIRT039744)

    Block miRNA regulation of human, mouse, rat RANBP10 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RANBP10 (see all 109):
    hsa-miR-3152-3p hsa-miR-3194-5p hsa-miR-30d hsa-miR-3916 hsa-miR-4267 hsa-miR-890 hsa-miR-30a hsa-miR-4293
    SwitchGear 3'UTR luciferase reporter plasmidRANBP10 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for RANBP10
    Predesigned siRNA for gene silencing in human, mouse, rat RANBP10

    Gene Editing
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RANBP10


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RBP10_HUMAN, Q6VN20: Cytoplasm, cytosol. Nucleus. Note=Predominantly cytoplasmic
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    nucleus5
    cytoskeleton2

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm ----
    GO:0005829cytosol IEA--
    GO:0005881cytoplasmic microtubule IEA--

    Find genes that share ontologies with RANBP10           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RANBP10 About    
    See pathways by source

    SuperPathContained pathways About
    1Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
    Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)


    1 BioSystems Pathway for RANBP10
        Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RANBP10
    Interactions:

        GeneGlobe Interaction Network for RANBP10

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RANBP10 (Q6VN203 ENSP000003165894) via UniProtKB, MINT, STRING, and/or I2D (see all 56)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CACHD1Q5VU973, ENSP000002900394I2D: score=3 STRING: ENSP00000290039
    METP085813, ENSP000003172724I2D: score=2 STRING: ENSP00000317272
    RANP628263, ENSP000003961274I2D: score=2 STRING: ENSP00000396127
    CNTNAP4Q9C0A03, ENSP000004176284I2D: score=2 STRING: ENSP00000417628
    IGSF1Q8N6C53, ENSP000003550104I2D: score=3 STRING: ENSP00000355010
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000226microtubule cytoskeleton organization IEA--

    Find genes that share ontologies with RANBP10           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RANBP10 (RBP10)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RANBP10 gene: 
    NM_020850.1  

    Unigene Cluster for RANBP10:

    RAN binding protein 10
    Hs.368569  [show with all ESTs]
    Unigene Representative Sequence: AY337313
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000317506(uc002eud.3 uc010ceo.3 uc010vju.2 uc010vjv.2)
    ENST00000448631(uc010vjw.1) ENST00000602506 ENST00000602677 ENST00000602525
    ENST00000602638 ENST00000602815 ENST00000602887 ENST00000411657 ENST00000536251
    ENST00000425512(uc010vjx.1 uc010vjy.1)
    miRNA
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    Block miRNA regulation of human, mouse, rat RANBP10 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RANBP10 (see all 109):
    hsa-miR-3152-3p hsa-miR-3194-5p hsa-miR-30d hsa-miR-3916 hsa-miR-4267 hsa-miR-890 hsa-miR-30a hsa-miR-4293
    SwitchGear 3'UTR luciferase reporter plasmidRANBP10 3' UTR sequence
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector: RANBP10 (NM_020850)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RANBP10
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      QuantiTect SYBR Green Assays in human, mouse, rat RANBP10
      QuantiFast Probe-based Assays in human, mouse, rat RANBP10

    Additional mRNA sequence: 

    AB040897.1 AK000686.1 AK055634.1 AK055727.1 AK295171.1 AK295530.1 AK298806.1 AK304030.1 
    AL137299.1 AY337313.1 BC099917.1 BC121176.1 BC121177.2 

    5 DOTS entries:

    DT.216147  DT.100035957  DT.100816963  DT.97843941  DT.120718318 

    Selected AceView cDNA sequences (see all 165):

    AB040897 AA329467 BM767290 AI769190 BE891087 BQ006448 AL041853 AY337313 
    BM920479 AL041852 BM770279 CD364797 AI342430 BX105426 T35156 AI436141 
    AI275875 AI240205 CA395964 F12528 F04079 AW593043 CK300853 T15985 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for RANBP10 (see all 6)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b ^ 16
    SP1:                                                                                                                  
    SP2:                    -     -                                                                                       
    SP3:                                                                                                                  
    SP4:                                                  -                                                               
    SP5:                                                                                                                  


    ECgene alternative splicing isoforms for RANBP10

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RANBP10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    RANBP10 Expression
    About this image

    RANBP10 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RANBP10 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.368569

    UniProtKB/Swiss-Prot: RBP10_HUMAN, Q6VN20
    Tissue specificity: Broadly expressed, with highest levels in skeletal muscle

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RANBP10

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for RANBP10 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ranbp101 , 5 RAN binding protein 101, 5 91.72(n)1
    97.74(a)1
      8 (53.04 cM)5
    743341  NM_145824.41  NP_665823.21 
     1057683085 
    chicken
    (Gallus gallus)
    Aves RANBP101 RAN binding protein 10 80.46(n)
    90.09(a)
      415653  XM_004944059.1  XP_004944116.1 
    lizard
    (Anolis carolinensis)
    Reptilia RANBP106
    RAN binding protein 10
    85(a)
    1 ↔ 1
    GL343295.1(711685-758501)
    zebrafish
    (Danio rerio)
    Actinopterygii ranbp101 RAN binding protein 10 75.91(n)
    82.88(a)
      793293  NM_001045050.1  NP_001038515.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta RanBPM6
    Ran-binding protein M
    28(a)
    1 → many
    2R(6317217-6324086)
    worm
    (Caenorhabditis elegans)
    Secernentea Y54E5A.76
    Protein Y54E5A.7, isoform a
    23(a)
    1 → many
    I(14711081-14715030) WBGene00013202
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes VID30(YGL227W)4 Protein involved in proteasome-dependent catabolite more   --   7(69671-72547) 852624  NP_011287.1 


    ENSEMBL Gene Tree for RANBP10 (if available)
    TreeFam Gene Tree for RANBP10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RANBP10 gene
    SPRYD32  RANBP92  
    1 SIMAP similar gene for RANBP10 using alignment to 9 protein entries:     RBP10_HUMAN (see all proteins):
    RANBP9

    Find genes that share paralogs with RANBP10           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RANBP10 (see all 1301)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1837642101,2
    --67756557(+) GAATAG/TCTGGG 1 -- ds50010--------
    rs1399653211,2
    --67756772(+) AAGCCA/GTTTCA 1 -- ds50010--------
    rs1115317741,2
    C,F--67756855(+) AAGGCA/CCCTGA 1 -- ds50013Minor allele frequency- C:0.05CSA WA 121
    rs1153672201,2
    C,F--67756927(+) AAGGGG/ATGCCA 1 -- ds50011Minor allele frequency- A:0.02WA 118
    rs665864551,2
    C--67756941(+) TCAGT-/AAGACT 1 -- ds50010--------
    rs1453542011,2
    --67757034(+) TTTTTG/TGTCTC 1 -- ut310--------
    rs124452801,2
    C,F,H--67757036(+) TTTTGT/GCTCTC 1 -- ut31 ese36Minor allele frequency- G:0.01NS EA NA 684
    rs12451,2
    C,H--67757160(+) GTGCAC/GAATGT 1 -- ut315Minor allele frequency- G:0.00MN NS EA 602
    rs1880655811,2
    --67757411(+) GAAGGC/TGCTAG 1 -- ut310--------
    rs1813063981,2
    --67757425(+) GCCAGA/GCAGTC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for RANBP10 (67757005 - 67840555 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for RANBP10:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2662518CNV Deletion23128226
    nsv1842CNV Insertion18451855
    nsv524363CNV Loss19592680
    nsv522852CNV Gain19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RANBP10
    DNA2.0 Custom Variant and Variant Library Synthesis for RANBP10

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 614031    OMIM disorders: --


    Find genes that share disorders with RANBP10           About GenesLikeMe


    Export disorders for RANBP10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RANBP10 gene, integrated from 10 sources (see all 24):
    (articles sorted by number of sources associating them with RANBP10)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel MET-interacting protein shares high sequence similarity with RanBPM, but fails to stimulate MET-induced Ras/Erk signaling. (PubMed id 14684163)1, 2, 3 Wang D.... Wu G. (Biochem. Biophys. Res. Commun. 2004)
    2. RanBP10 is a cytoplasmic guanine nucleotide exchange factor that modulates noncentrosomal microtubules. (PubMed id 18347012)1, 2 Schulze H....Shivdasani R.A. (J. Biol. Chem. 2008)
    3. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10819331)1, 2 Nagase T.... Ohara O. (DNA Res. 2000)
    4. The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells. (PubMed id 23667531)1 Cox J.L....Rizzino A. (PLoS ONE 2013)
    5. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (J. Cell. Sci. 2012)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    7. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    8. NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function. (PubMed id 23022380)1 Yatim A....Benkirane M. (Mol. Cell 2012)
    9. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 57610 HGNC: 29285 AceView: RANBP10 Ensembl:ENSG00000141084 euGenes: HUgn57610
    ECgene: RANBP10 H-InvDB: RANBP10

    (According to HUGE)
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    HUGE: KIAA1464

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RANBP10 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for RANBP10 gene:
    Search GeneIP for patents involving RANBP10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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