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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RANBP1 Gene

protein-coding   GIFtS: 59
GCID: GC22P020103

RAN binding protein 1
 Explore 11 diseases affiliated with
RANBP1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for RANBP1    

Aliases
for RANBP1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
RAN Binding Protein 11 2
HTF9A1 2
Ran-Binding Protein 12 3
Ran-Specific GTPase-Activating Protein2
RanBP13

External Ids:    HGNC: 98471   Entrez Gene: 59022   Ensembl: ENSG000000999017   OMIM: 6011805   UniProtKB: P434873   

Export aliases for RANBP1 gene to outside databases

Previous GC identifers: GC22P017045 GC22P018478 GC22P018479 GC22P003725


Summaries
for RANBP1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for RANBP1:
Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds
to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP
hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92%
similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by
inhibiting RCC1-stimulated guanine nucleotide release from RAN. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: RANG_HUMAN, P43487
Function: Inhibits GTP exchange on Ran. Forms a Ran-GTP-RANBP1 trimeric complex. Increase GTP hydrolysis induced by the
Ran GTPase activating protein RANGAP1. May act in an intracellular signaling pathway which may control the progression
through the cell cycle by regulating the transport of protein and nucleic acids across the nuclear membrane

Gene Wiki entry for RANBP1


Genomic Views
for RANBP1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000022.10  NC_018933.1  NT_011519.10  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RANBP1 gene promoter:
         SRF   Spz1   Pax-5   SRF (504 AA)   YY1   CREB   deltaCREB   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: RANBP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for RANBP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RANBP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q11.21   Ensembl cytogenetic band:  22q11.21   HGNC cytogenetic band: 22q11.21

RANBP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RANBP1 gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22P020103:  view genomic region     (about GC identifiers)

Start:
 20,103,461 bp from pter      End:
 20,114,878 bp from pter
Size:
 11,418 bases      Orientation:
 plus strand

Proteins
for RANBP1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: RANG_HUMAN, P43487 (See protein sequence)
Recommended Name: Ran-specific GTPase-activating protein  
Size: 201 amino acids; 23310 Da
2 PDB 3D structures from and Proteopedia for RANBP1:
1K5D (3D)        1K5G (3D)    

Explore the universe of human proteins at neXtProt for RANBP1: NX_P43487

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P43487

    • RANBP1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_002873.1  
    ENSEMBL proteins: 
     ENSP00000404724   ENSP00000390139   ENSP00000384925   ENSP00000327583   ENSP00000395472  
     ENSP00000404126   ENSP00000400940   ENSP00000404298   ENSP00000413502   ENSP00000398300  
     ENSP00000401564  
    Reactome Protein details: P43487
    Human Recombinant Protein Products: 
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    Novus Biologicals RANBP1 Proteins
    Novus Biologicals RANBP1 Lysate
    Browse Sino Biological Recombinant Proteins
    ProSpec Recombinant Protein for RANBP1
    Uscn Proteins for RANBP1

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus TAS16130169
    GO:0005635nuclear envelope TAS--
    GO:0005737cytoplasm TAS16130169
    GO:0005813centrosome IEA--


    RANBP1 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for RANBP1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    RANBP1 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR000156 Ran_bind_dom
     IPR011993 PH_like_dom

    Graphical View of Domain Structure for InterPro Entry P43487

    ProtoNet protein and cluster: P43487

    1 Blocks protein family: IPB000156 RanBP1 domain

    UniProtKB/Swiss-Prot: RANG_HUMAN, P43487
    Similarity: Belongs to the RANBP1 family
    Similarity: Contains 1 RanBD1 domain


    Function
    for RANBP1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: RANG_HUMAN, P43487
    Function: Inhibits GTP exchange on Ran. Forms a Ran-GTP-RANBP1 trimeric complex. Increase GTP hydrolysis induced by the
    Ran GTPase activating protein RANGAP1. May act in an intracellular signaling pathway which may control the progression
    through the cell cycle by regulating the transport of protein and nucleic acids across the nuclear membrane

         Genatlas biochemistry entry for RANBP1:
    Ran (Ras-related small nuclear protein) binding protein 1,stimulating Ran GAP1-induced GTP hydrolysis by RAS-related
    protein Ran/TC4,also,in absence of RAS-GAP negative regulator of the regulator of chromosome condensation (CHC1L) in
    association with Ran/TC4

    miRNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005092GDP-dissociation inhibitor activity TAS7616957
    GO:0005096GTPase activator activity IEA--
    GO:0008536Ran GTPase binding TAS7882974


    RANBP1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for RANBP1:
     Decreased p24 protein expressi 

    Animal Models:
         Mouse knock-out Ranbp1tm1Yyo for RANBP1
         3 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Ranbp1):
     cellular  growth/size  reproductive system 

    RANBP1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for RANBP1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/8 super-pathways (see all 8) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1HIV Infection
    		HIV Infection1.00
    		Host Interactions of HIV factors0.64
    2Late Phase of HIV Life Cycle
    		Late Phase of HIV Life Cycle1.00
    		HIV Life Cycle0.90
    3Translocation of Influenza A virus nonstructural protein 1 (NS1A) into the nucleus
    		Interactions of Rev with host cellular proteins0.72
    		Rev-mediated nuclear export of HIV-1 RNA0.71
    4Cytoskeletal Signaling
    		Cytoskeletal Signaling1.00
    5Disease
    		Disease1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for RANBP1
        Ran Pathway
    SUMO Pathway

    1 Cell Signaling Technology (CST) Pathway for RANBP1
        Cytoskeletal Signaling

    1 BioSystems Pathway for RANBP1 
        E2F transcription factor network

    5/7        Reactome Pathways for RANBP1 (see all 7)
        HIV Life Cycle
    Rev-mediated nuclear export of HIV-1 RNA
    HIV Infection
    Late Phase of HIV Life Cycle
    Interactions of Rev with host cellular proteins



    RANBP1 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RANBP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/53 Interacting proteins for RANBP1 (P434871, 2, 3 ENSP000003275834) via UniProtKB, MINT, STRING, and/or I2D (see all 53)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RANP628262, 3, ENSP000003961274MINT-73242 I2D: score=6 STRING: ENSP00000396127
    MPGP293721, 3, ENSP000002194314EBI-1032909,EBI-1043398 I2D: score=2 STRING: ENSP00000219431
    NAP1L4Q997333, ENSP000003699154I2D: score=5 STRING: ENSP00000369915
    RCC1P187543, ENSP000003629374I2D: score=3 STRING: ENSP00000362937
    CD93Q9NPY33, ENSP000002460064I2D: score=2 STRING: ENSP00000246006
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007051spindle organization IEA--
    GO:0007165signal transduction TAS16130169
    GO:0016032viral reproduction TAS--
    GO:0046604positive regulation of mitotic centrosome separation IEA--
    GO:0046907intracellular transport IEA--


    RANBP1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for RANBP1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    RANBP1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for RANBP1

    1 HMDB Compound for RANBP1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--
    4 Novoseek chemical compound relationships for RANBP1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    gtp 73.1 17 10779340 (3), 10995230 (2), 10322113 (1), 9398678 (1) (see all 8)
    gdp 57.6 2 15454457 (1), 15733044 (1)
    leptomycin b 52.3 4 10779340 (1), 16041368 (1)
    threonine 2.38 1 15733044 (1)

    Search CenterWatch for drugs/clinical trials and news about RANBP1 / RANG 

    Transcripts
    for RANBP1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for RANBP1 gene: 
    NM_002882.2  

    Unigene Cluster for RANBP1:

    RAN binding protein 1
    Hs.24763  [show with all ESTs]
    Unigene Representative Sequence: AK094410
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000432879 ENST00000435265 ENST00000402752(uc011ahl.1 uc002zro.1 uc002zrp.3)
    ENST00000488484 ENST00000331821 ENST00000411892 ENST00000467920 ENST00000416427
    ENST00000421656 ENST00000423859(uc021wlq.1) ENST00000418705 ENST00000448394
    ENST00000486575 ENST00000430524

    miRNA
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    hsa-miR-623 hsa-miR-4277
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    Inhib. RNA
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    Additional cDNA sequence: 

    AK094410.1 AK097659.1 AK223506.1 AK293502.1 AK300927.1 BC071998.1 CR456556.1 D38076.1 
    X83617.1 

    19 DOTS entries:

    DT.100762584  DT.452618  DT.100821145  DT.100821133  DT.95158595  DT.95158593  DT.97797266  DT.120644455 
    DT.100821144  DT.120644518  DT.100037501  DT.65284203  DT.97820864  DT.100037502  DT.121179473  DT.91781574 
    DT.95158591  DT.97799420  DT.91781588 

    24/357 AceView cDNA sequences (see all 357):

    BG527409 BE221519 T31529 AI589059 BQ927398 AI335716 CB157924 AA961604 
    AW054822 AI795907 CB125330 AI655203 BM264070 BF001980 BU688935 D38076 
    BG576793 AW404200 BP431904 AI744789 BQ653572 BE348381 CK824836 AA587132 

    GeneLoc Exon Structure


    Expression
    for RANBP1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RANBP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CCGAAAAAGT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See RANBP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RANBP1

    SOURCE GeneReport for Unigene cluster: Hs.24763
        SABiosciences Custom PCR Arrays for RANBP1
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    In Situ
    Assay Products:     
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    Orthologs
    for RANBP1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RANBP1 gene from 9/30 species (see all 30)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Ranbp11 , 5 RAN binding protein 11, 5 88.33(n)1
    95(a)1    		   16 (11.30 cM)5
    193851  NM_011239.21  NP_035369.21 
     182397845 
    chicken
    (Gallus gallus)    		 Aves RANBP11 RAN binding protein 1 81.33(n)
    88(a)    		   416787  NM_001006183.1  NP_001006183.1 
    lizard
    (Anolis carolinensis)    		 Reptilia RANBP16
    		 --
    		 81(a)
    		 1 ↔ 1
    		 GL343364.1(1027192-1031590)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia MGC760282 hypothetical protein MGC76028 76.49(n)    BC061426.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii Dr.124112 Danio rerio Ran binding protein 1 mRNA, complete cds 73.19(n)    AF364085.1 
    honey bee
    (Apis mellifera)    		 Insecta --
    		 --
    		 39(a)
    		 1 ↔ 1
    		 GroupUn.191(40804-41998)
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes YRB11 Yrb1p 56.34(n)
    55.48(a)    		   851565   NP_010285.1 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons SIRANBP1 Ran-binding protein 1-a 54.1(n)
    44.81(a)    		   837225  NM_100588.3  NP_172194.1 
    rice
    (Oryza sativa)    		 Liliopsida Os03g02928001 hypothetical protein 57.19(n)
    49.73(a)    		   4332513  NM_001056341.1  NP_001049806.1 


    ENSEMBL Gene Tree for RANBP1 (if available)
    TreeFam Gene Tree for RANBP1 (if available) 

    Paralogs
    for RANBP1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RANBP1 gene
    RANBP22  RGPD62  RGPD22  RGPD42  RGPD32  RGPD12  RGPD82  RGPD52  
    6 SIMAP similar genes for RANBP1 using alignment to 10 protein entries:     RANG_HUMAN (see all proteins):
    RGPD2    RANBP2    RGPD1    RGPD3    RGPD8    RGPD4

    RANBP1 for paralogs           About GeneDecksing


    5 Pseudogenes.org Pseudogenes for RANBP1
    PGOHUM00000239523 PGOHUM00000237269 PGOHUM00000237510 PGOHUM00000245168 PGOHUM00000236330


    Genomic Variants
    for RANBP1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/209 NCBI SNPs in RANBP1 are shown (see all 209)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 22 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs284590521,2
    		C--20103114(+) CAGGGA/GGATCA 4 -- us2k1 int11Minor allele frequency- G:0.00NA 2
    rs1929922311,2
    		C,--20103158(+) AACCCA/GGGATA 4 -- int1 us2k10--------
    rs798861491,2
    		C,F,--20103189(+) TCTAGT/CCTGAC 4 -- int1 us2k13Minor allele frequency- C:0.05NA EA EU 839
    rs1852900721,2
    		C,--20103344(+) TACTGC/TCCCCG 4 -- int1 us2k10--------
    rs1389142331,2
    		--20103416(+) TGCCCA/GCTGTG 4 -- int1 us2k10--------
    rs591773731,2
    		C,F,--20103462(+) CGCCAG/TATCCT 4 -- int1 us2k14Minor allele frequency- T:0.21WA CSA 124
    rs1421425021,2
    		--20103482(+) CTCCCA/CACTGG 4 -- us2k1 int10--------
    rs1156183511,2
    		--20103495(+) CATGGA/TCAGGC 4 -- int1 us2k11Minor allele frequency- T:0.01WA 118
    rs1997857101,2
    		--20103539(+) AGAGGA/GGCGTC 4 -- us2k1 int10--------
    rs2000135451,2
    		--20104146(+) TGGGGA/CCAGAT 4 -- int1 us2k10--------

    HapMap Linkage Disequilibrium report for RANBP1 (20103461 - 20114878 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 4 variations for RANBP1
         3 CNVs: 30155 4117 31071
         1 Indel: 46208

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    Disorders / Diseases
    for RANBP1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    RANBP1 for disorders           About GeneDecksing

    OMIM gene information: 601180    OMIM disorders: --

    11 diseases for RANBP1:    About MalaCards
    human t-cell leukemia virus type 1    velocardiofacial syndrome    digeorge syndrome    t-cell leukemia
    lymphocytic leukemia    leukemia    immunodeficiency    breast carcinoma
    breast cancer    carcinoma    malaria

    3 Novoseek disease relationships for RANBP1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    shock 0 1 12872216 (1)
    cancer 0 2 19270727 (2)
    immunodeficiency 0 3 9111043 (2)

    Human Genome Epidemiology (HuGE) Navigator: RANBP1 (4 documents)

    Export disorders for RANBP1 gene to outside databases

    Publications
    for RANBP1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RANBP1 gene, integrated from 9 sources (see all 115):
    (articles sorted by number of sources associating them with RANBP1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. RanBP1, a Ras-like nuclear G protein binding to Ran/TC4, inhibits RCC1 via Ran/TC4. (PubMed id 7616957)1, 2, 3, 9 Hayashi N.... Nishimoto T. (1995)
    2. A role for RanBP1 in the release of CRM1 from the nuclear pore complex in a terminal step of nuclear export. (PubMed id 10330396)1, 3, 9 Kehlenbach R.H....Gerace L. (1999)
    3. Co-activation of RanGTPase and inhibition of GTP dissociation by Ran- GTP binding protein RanBP1. (PubMed id 7882974)1, 2, 9 Bischoff F.R.... Ponstingl H. (1995)
    4. A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (2004)
    5. Dynamic and equilibrium studies on the interaction of Ran with its effector, RanBP1. (PubMed id 9315840)1, 9 Kuhlmann J....Wittinghofer A. (1997)
    6. RanBP1 downregulation sensitizes cancer cells to taxol in a caspase-3-dependent manner. (PubMed id 19270727)1, 9 Rensen W.M....Lavia P. (2009)
    7. RanBP1 stabilizes the interaction of Ran with p97 nuclear protein import. (PubMed id 8909533)1, 9 Chi N.C....Adam S.A. (1996)
    8. Facilitated nucleocytoplasmic shuttling of the Ran binding protein RanBP1. (PubMed id 10779340)1, 9 Plafker K. and Macara I.G. (2000)
    9. Mammalian RanBP1 regulates centrosome cohesion during mitosis. (PubMed id 12840069)1, 9 Di Fiore B....Lavia P. (2003)
    10. Different binding domains for Ran-GTP and Ran-GDP/RanBP1 on nuclear import factor p97. (PubMed id 9045717)1, 9 Chi N.C....Adam S.A. (1997)

    External Searches for RANBP1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    Genome Databases showing RANBP1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 5902 HGNC: 9847 AceView: RANBP1 Ensembl:ENSG00000099901 euGenes: HUgn5902
    ECgene: RANBP1 H-InvDB: RANBP1

    Other Databases showing RANBP1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing RANBP1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RANBP1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for RANBP1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for RANBP1 gene:
    Search GeneIP for patents involving RANBP1

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