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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RAMP3 Gene

protein-coding   GIFtS: 56
GCID: GC07P045163

receptor (G protein-coupled) activity modifying protein...

(Previous names: receptor activity modifying protein 3, receptor (calcitonin)...)
 Explore 9 diseases affiliated with
RAMP3 via our new
 Human Malady Compendium 
Biological research products
for RAMP3
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Receptor (G Protein-Coupled) Activity Modifying Protein 31 2     CRLR Activity-Modifying Protein 32 3
Receptor (Calcitonin) Activity Modifying Protein 31 2     Calcitonin Receptor-Like Receptor Activity Modifying Protein 32
Receptor Activity Modifying Protein 31 2     Receptor Activity-Modifying Protein 32
Calcitonin-Receptor-Like Receptor Activity-Modifying Protein 32 3     Receptor-Activity-Modifying Protein 32

External Ids:    HGNC: 98451   Entrez Gene: 102682   Ensembl: ENSG000001226797   OMIM: 6051555   UniProtKB: O608963   

Export aliases for RAMP3 gene to outside databases

Previous GC identifers: GC07P044843 GC07P044938 GC07P044970


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RAMP3:
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called
receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an
extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like
receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a
calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP
family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor. (provided
by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: RAMP3_HUMAN, O60896
Function: Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a
receptor for adrenomedullin (AM) together with CALCRL

summary for RAMP3:
Calcitonin and related receptors are a family of G-protein-coupled receptors that comprises of eight
subtypes; CT, AMY1, AMY2, AMY3, CALCR, CGRP, AM1 and AM2. The receptors have a wide biological distribution;
high concentrations are found in the brain, lung, liver, heart and spleen with lower expression levels
present in the testes, gastrointestinal tract and thyroid. The main function of CT receptors is to inhibit
bone reabsorption and enhance calcium excretion by the kidneys. AMY receptors are heterodimers of the CT
receptor and receptor activating modifying proteins (RAMP) 1-3, which have been implicated in type II
diabetes pathology. The CALCRL receptor alone is non-functioning, but forms heterodimers with RAMPs to form
the CGRP (CALCRL with RAMP1), AM1 (CALCRL with RAMP2) and AM2 (CALCRL with RAMP3) receptors. Their main
function is inducing vasodilation, which causes hypotension.

Gene Wiki entry for RAMP3


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.1  NT_007819.17  NT_079592.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RAMP3 gene promoter:
         GR   Nkx2-2   NCX/Ncx   GR-beta   Evi-1   POU2F1   FOXO4   POU2F1a   GR-alpha   Ik-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRAMP3 promoter sequence
   Search SABiosciences Chromatin IP Primers for RAMP3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RAMP3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p13-p12   Ensembl cytogenetic band:  7p13   HGNC cytogenetic band: 7p13-p12

RAMP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAMP3 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P045163:  view genomic region     (about GC identifiers)

Start:
45,197,367 bp from pter      End:
45,225,901 bp from pter
Size:
28,535 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 45,236,530-45,263,012     

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RAMP3_HUMAN, O60896 (See protein sequence)
Recommended Name: Receptor activity-modifying protein 3 precursor  
Size: 148 amino acids; 16518 Da
Subunit: Heterodimer of CALCRL and RAMP3 (By similarity)
Subcellular location: Membrane; Single-pass type I membrane protein
Secondary accessions: Q7Z2Y1

Explore the universe of human proteins at neXtProt for RAMP3: NX_O60896

RAMP3 Protein expression data from MOPED and PaxDb:    About this image 
RAMP3 Protein Expression

REFSEQ proteins: NP_005847.1  
ENSEMBL proteins: 
 ENSP00000242249   ENSP00000419012   ENSP00000418460  
Reactome Protein details: O60896
Human Recombinant Protein Products for RAMP3: 
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Uscn Proteins for RAMP3

Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005764colocalizes with lysosome IDA15613468
GO:0005886plasma membrane TAS--
GO:0005887integral to plasma membrane TAS9620797
GO:0009986cell surface IDA14722252
GO:0043235receptor complex IDA15613468

RAMP3 for ontologies           About GeneDecksing



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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

RAMP3 for domains           About GeneDecksing

1 InterPro domain/family:
 IPR006985 RAMP

Graphical View of Domain Structure for InterPro Entry O60896

ProtoNet protein and cluster: O60896

1 Blocks protein family: IPB006985 Receptor activity modifying protein

UniProtKB/Swiss-Prot: RAMP3_HUMAN, O60896
Similarity: Belongs to the RAMP family


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: RAMP3_HUMAN, O60896
Function: Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a
receptor for adrenomedullin (AM) together with CALCRL

     Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0004872receptor activity IDA10882736
GO:0005515protein binding IPI15613468
GO:0008565protein transporter activity IDA10882736
GO:0015026coreceptor activity IEA--
     
RAMP3 for ontologies           About GeneDecksing


Phenotypes:
     1 MGI mutant phenotype (inferred from 1 allele(MGI details for Ramp3):
 growth/size 

RAMP3 for phenotypes           About GeneDecksing

Animal Models:
     Mouse knock-out Ramp3tm1Kmca for RAMP3
   inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for RAMP3 

miRNA
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAMP3


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways - 5/6 super-pathways (see all 6About this table 
See pathways by source

Super-pathwaycontained gene-specific pathways
1Signaling by GPCR
Signaling by GPCR1.00
Signal Transduction0.56
GPCR downstream signaling0.89
2G beta:gamma signalling through PLC beta
Class B/2 (Secretin family receptors)0.20
G alpha (s) signalling events0.14
3Calcitonin-like ligand receptors
Calcitonin-like ligand receptors1.00
4Class A/1 (Rhodopsin-like receptors)
GPCR ligand binding0.75
5Calcium Regulation in the Cardiac Cell
Myometrial Relaxation and Contraction Pathways0.43

Pathway sources
See GeneCards unified pathways
Show all pathways


1 BioSystems Pathway for RAMP3 
    Myometrial Relaxation and Contraction Pathways

5/7        Reactome Pathways for RAMP3 (see all 7)
    GPCR downstream signaling
Signal Transduction
Signaling by GPCR
Calcitonin-like ligand receptors
GPCR ligand binding


1         Kegg Pathway  (Kegg details for RAMP3):
    Vascular smooth muscle contraction


RAMP3 for pathways           About GeneDecksing

Interactions:

    SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RAMP3

STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

5/8 Interacting proteins for RAMP3 (O608963 ENSP000002422494) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
InteractantInteraction Details
GeneCardExternal ID(s)
PDCD6IPQ8WUM43, ENSP000003073874I2D: score=4 STRING: ENSP00000307387
CALCRLQ166023, ENSP000003761774I2D: score=2 STRING: ENSP00000376177
CALCRP309883, ENSP000003525614I2D: score=1 STRING: ENSP00000352561
VIPR1P322413, ENSP000003272464I2D: score=1 STRING: ENSP00000327246
SLC31A2O154323, ENSP000002593924I2D: score=1 STRING: ENSP00000259392
About this table

Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0001921positive regulation of receptor recycling IDA15613468
GO:0006816calcium ion transport IDA10882736
GO:0006886intracellular protein transport IEA--
GO:0007186G-protein coupled receptor signaling pathway IEA--
GO:0008277regulation of G-protein coupled receptor protein signaling pathway IEA--

RAMP3 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

RAMP3 for compounds           About GeneDecksing

Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Compounds for RAMP3 available from Tocris Bioscience    About this table
CompoundAction CAS #
Amylin Endogenous peptide agonist for amylin, calcitonin, CGRP and adrenomedullin receptors [122384-88-7]
AC 187Potent and selective amylin receptor antagonist[151804-77-2]

1 DrugBank Compound for RAMP3    About this table
CompoundSynonyms CAS #TypeActionsPubMed Ids
Pramlintide-- 151126-32-8targetagonist19273748 15494035 17139284 18593822 17016423 11772274 20015292 20357016

3 Novoseek chemical compound relationships for RAMP3 gene    About this table
Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
bibn 4096 bs 88.1 1 11804624 (1)
adenylate 27.4 1 14631146 (1)
nitric oxide 0 2 14717924 (1)

Search CenterWatch for drugs/clinical trials and news about RAMP3 

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for RAMP3 gene: 
NM_005856.2  

Unigene Cluster for RAMP3:

Receptor (G protein-coupled) activity modifying protein 3
Hs.25691  [show with all ESTs]
Unigene Representative Sequence: AK128765
3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000242249(uc003tnb.3) ENST00000481345 ENST00000496212

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Clone
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Additional cDNA sequence: 

AJ001016.1 AK128765.1 AK222469.1 AK311871.1 AY265459.1 BC022304.1 BC053852.1 

4 DOTS entries:

DT.95149833  DT.213154  DT.121055189  DT.121055186 

24/87 AceView cDNA sequences (see all 87):

CA392680 AA400979 BG570492 BQ878867 CA842846 H68206 CA439283 CR592589 
BI062513 AI419200 BC053852 AW013906 BU951316 BI062518 BG538402 AY265459 
BQ787093 BQ941120 AI004174 BE670331 AK128765 BX090857 CB267783 BU678090 

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for RAMP3    About this scheme

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c · 4d ^ 5a · 5b
SP1:                    -     -                       -     -               
SP2:                          -                                             
SP3:                    -     -                 -     -     -               
SP4:                    -     -                                             
SP5:                                                                        


ECgene alternative splicing isoforms for RAMP3

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

RAMP3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGCTTGTGGC
RAMP3 Expression
About this image
See RAMP3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RAMP3

SOURCE GeneReport for Unigene cluster: Hs.25691

UniProtKB/Swiss-Prot: RAMP3_HUMAN, O60896
Tissue specificity: Strongly expressed in lung, breast, immune system and fetal tissues

    SABiosciences Expression via Pathway-Focused PCR Array including RAMP3: 
          Obesity in human mouse rat

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In Situ
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAMP3

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for RAMP3 gene from 3/10 species (see all 10)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
chicken
(Gallus gallus)
Aves RAMP31 receptor (G protein-coupled) activity modifying protein more 62.99(n)
67.65(a)
  420786  NM_001144973.1  NP_001138445.1 
lizard
(Anolis carolinensis)
Reptilia RAMP36
--
47(a)
1 ↔ 1
GL344190.1(46132-51432)
zebrafish
(Danio rerio)
Actinopterygii si:ch73-334d15.26
si:ch73-334d15.2
25(a)
1 ↔ 1
24(38200029-38217946)


ENSEMBL Gene Tree for RAMP3 (if available)
TreeFam Gene Tree for RAMP3 (if available) 

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for RAMP3 gene
RAMP22  RAMP12  
2 SIMAP similar genes for RAMP3 using alignment to 4 protein entries:     RAMP3_HUMAN (see all proteins):
RAMP1    RAMP2

RAMP3 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/617 NCBI SNPs in RAMP3 are shown (see all 617    About this table
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 7 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs77883251,2
C,F,A,H--45195543(+) CACTGC/TAGAGC 1 -- us2k1 tfbs310Minor allele frequency- T:0.27NS EA NA WA 770
rs2007349821,2
--45195700(+) AGACT-/AAGACTC 1 -- us2k10--------
rs37575751,2
C,F,H--45195735(+) AGTCTG/ATGTGG 1 -- us2k113Minor allele frequency- A:0.30NS EA WA NA 1178
rs1859255671,2
--45195771(+) ACCATA/CCTCTT 1 -- us2k10--------
rs1919130651,2
--45195816(+) GTAAGA/CCAGCC 1 -- us2k10--------
rs1825926101,2
--45195828(+) CCTGCA/TGCCCT 1 -- us2k10--------
rs64632651,2
C,F,A,H--45196053(+) CTCCCA/GAATAA 1 -- us2k1 tfbs325Minor allele frequency- N:0.00EA NA NS WA CSA 2386
rs1859207381,2
--45196123(+) GAAGGC/TAGCAG 1 -- us2k10--------
rs1908785451,2
--45196137(+) CTACGG/TCTCAG 1 -- us2k10--------
rs1116707351,2
--45196400(+) TCCTTC/TGCCTC 1 -- us2k12Minor allele frequency- T:0.03CSA WA 119

HapMap Linkage Disequilibrium report for RAMP3 (45197367 - 45225901 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for RAMP3
     2 CNVs: 4533 52231
     1 Indel: 69871

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

RAMP3 for disorders           About GeneDecksing

OMIM gene information: 605155    OMIM disorders: --

9 diseases for RAMP3:    About MalaCards
thyroiditis    pancreatic cancer    prostate carcinoma    pancreatitis
cerebritis    hypoxia    prostatitis    carcinoma
sepsis

2 Novoseek disease relationships for RAMP3 gene    About this table

Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
cardiac hypertrophy 18.1 1 15974887 (1)
heart failure 7.66 1 15300632 (1)

Human Genome Epidemiology (HuGE) Navigator: RAMP3 (3 documents)

Export disorders for RAMP3 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for RAMP3 gene, integrated from 9 sources (see all 100):
(articles sorted by number of sources associating them with RAMP3)
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  1. Identification of N-terminal receptor activity-modifying protein residues important for calcitonin gene-related peptide, adrenomedullin, and amylin receptor function. (PubMed id 18593822)1, 7, 9 Qi T....Hay D.L. (2008)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  3. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
  4. RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. (PubMed id 9620797)1, 2 McLatchie L.M.... Foord S.M. (1998)
  5. Functional characterization of two human receptor act ivity-modifying protein 3 variants. (PubMed id 20034525)1, 9 Bailey R.J....Hay D.L. (2010)
  6. N-Glycosylation and conserved cysteine residues in RAMP3 play a critical role for the functional expression of CRLR/RAMP3 adrenomedullin receptor. (PubMed id 12939163)1, 9 Flahaut M....Firsov D. (2003)
  7. Molecular basis of association of receptor activity-m odifying protein 3 with the family B G protein-coupled secretin receptor. (PubMed id 19886671)1, 9 Harikumar K.G....Miller L.J. (2009)
  8. Receptor activity-modifying protein (RAMP) isoform-specific regulation of adrenomedullin receptor trafficking by NHERF-1. (PubMed id 15805108)1, 9 Bomberger J.M....Parameswaran N. (2005)
  9. [Increased atria expression of receptor activity-modifying proteins in heart failure patients] (PubMed id 15300632)1, 9 Wang Y.F....Wang S.R. (2004)
  10. The seven amino acids of human RAMP2 (86) and RAMP3 (59) are critical for agonist binding to human adrenomedullin receptors. (PubMed id 11591721)1, 9 Kuwasako K....Eto T. (2001)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 10268 HGNC: 9845 AceView: RAMP3 Ensembl:ENSG00000122679 euGenes: HUgn10268
ECgene: RAMP3 Kegg: 10268 H-InvDB: RAMP3

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for RAMP3 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for RAMP3 gene:
Search GeneIP for patents involving RAMP3

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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