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RALGAPB Gene

protein-coding GIFtS: 50
GCID: GC20P037102

Ral GTPase Activating Protein, Beta Subunit (Non-Catalytic)

(Previous name: KIAA1219)
(Previous symbol: KIAA1219)

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(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
Ral GTPase Activating Protein, Beta Subunit (Non-Catalytic)¹ ²
KIAA1219¹ ² ³
RalGAPbeta²
Ral GTPase-Activating Protein Subunit Beta²
p170³

External Ids:	HGNC: 29221¹	Entrez Gene: 57148²	Ensembl: ENSG00000170471⁷	UniProtKB: Q86X10³

Export aliases for RALGAPB gene to outside databases

Previous GC identifers: GC20P036535 GC20P033838

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for RALGAPB Gene:

RALGAPB (Ral GTPase activating protein, beta subunit (non-catalytic)) is a protein-coding gene. GO annotations related to this gene include protein heterodimerization activity and Ral GTPase activator activity.

UniProtKB/Swiss-Prot: RLGPB_HUMAN, Q86X10

Function: Non-catalytic subunit of the heterodimeric RalGAP1 and RalGAP2 complexes which act as GTPase activators

for the Ras-like small GTPases RALA and RALB (By similarity)

Gene Wiki entry for RALGAPB (KIAA1219) Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence at NCBI GenBank:

NC_000020.10 NT_011362.11 NC_018931.2

Regulatory elements:

Search for regulatory transcription factor binding sites for RALGAPB
Other transcription factors

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Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RALGAPB

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q11.23 Ensembl cytogenetic band: 20q11.23 HGNC cytogenetic band: 20q11.23

RALGAPB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RALGAPB gene location

GeneLoc information about chromosome 20 GeneLoc Exon Structure

GeneLoc location for GC20P037102: view genomic region (about GC identifiers)

Start:	37,101,459 bp from pter	End:	37,207,504 bp from pter
Size:	106,046 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, antibodies-online, and/or GeneTex,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

UniProtKB/Swiss-Prot: RLGPB_HUMAN, Q86X10 (See protein sequence)

Recommended Name: Ral GTPase-activating protein subunit beta

Size: 1494 amino acids; 166799 Da

Subunit: Component of the heterodimeric RalGAP1 complex with RALGAPA1 and of the heterodimeric RalGAP2 complex

with RALGAPA2. Heterodimerization is required for activity (By similarity)

Sequence caution: Sequence=BAA86533.3; Type=Erroneous initiation; Note=Translation N-terminally shortened;

Sequence=BAC85649.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=CAB61346.1;

Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=CAD39096.1; Type=Erroneous

initiation; Note=Translation N-terminally shortened;

Secondary accessions: A2A2E8 Q5TG31 Q8N3D1 Q8WWC0 Q9H3X8 Q9UJR1 Q9ULK1 Q9Y3G9

Alternative splicing: 4 isoforms: Q86X10-1 Q86X10-2 Q86X10-3 Q86X10-4 (Splicing acceptor site is not canonical. No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RALGAPB: NX_Q86X10

Explore proteomics data for RALGAPB at MOPED

Post-translational modifications:

Modification sites at neXtProt

Modification sites at PhosphoSitePlus

See RALGAPB Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (3 alternative transcripts):

NP_001269846.1 NP_001269847.1 NP_065069.1

ENSEMBL proteins:

ENSP00000262879 ENSP00000380235 ENSP00000380233 ENSP00000416646 ENSP00000442959

ENSP00000380231

Reactome Protein details: Q86X10

RALGAPB Human Recombinant Protein Products:

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	antibodies-online kits for RALGAPB (4 products)

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GenesLikeMe)
About This Section

1 InterPro protein domain:

IPR000331 Rap_GAP_dom

Graphical View of Domain Structure for InterPro Entry Q86X10

ProtoNet protein and cluster: Q86X10

1 Blocks protein domain: IPB000331 Rap/ran-GAP

UniProtKB/Swiss-Prot: RLGPB_HUMAN, Q86X10

Similarity: Contains 1 Rap-GAP domain

Find genes that share domains with RALGAPB About GenesLikeMe

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: RLGPB_HUMAN, Q86X10

Function: Non-catalytic subunit of the heterodimeric RalGAP1 and RalGAP2 complexes which act as GTPase activators

for the Ras-like small GTPases RALA and RALB (By similarity)

Gene Ontology (GO): 4 molecular function terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005096	GTPase activator activity	--	--
GO:0005488	binding	--	--
GO:0017123	Ral GTPase activator activity	ISS	--
GO:0046982	protein heterodimerization activity	ISS	--

Find genes that share ontologies with RALGAPB About GenesLikeMe

Phenotypes:
1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Ralgapb):

mortality/aging

Find genes that share phenotypes with RALGAPB About GenesLikeMe

Animal Models:

genOway: Develop your customized and physiologically relevant rodent model for RALGAPB

miRNA Products:		miRTarBase miRNAs that target RALGAPB: hsa-mir-342-3p (MIRT043719), hsa-mir-328-3p (MIRT043758), hsa-mir-615-3p (MIRT040158), hsa-mir-421 (MIRT039454), hsa-let-7b-5p (MIRT052119), hsa-let-7d-5p (MIRT032129)

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In Situ Assay
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Flow Cytometry
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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
About This Section

Subcellular locations from COMPARTMENTS:

Compartment	Confidence
cytosol	2
mitochondrion	1
nucleus	1
peroxisome	1
plasma membrane	1

About this image

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GenesLikeMe, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
About This Section

SuperPaths for RALGAPB About

See pathways by source

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by

SuperPath

Contained pathways About

Clathrin derived vesicle budding

Membrane Trafficking

0.32

Translocation of GLUT4 to the Plasma Membrane

0.32

Find genes that share SuperPaths with RALGAPB About GenesLikeMe

Pathways by source See SuperPaths
Show all pathways

1 Reactome Pathway for RALGAPB

Translocation of GLUT4 to the plasma membrane

Custom Pathway & Disease-focused RT² Profiler PCR Arrays for RALGAPB
Interactions:

Search GeneGlobe Interaction Network for RALGAPB

STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

Selected Interacting proteins for RALGAPB (Q86X10³ ENSP00000262879⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 8)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
RALGAPA2	Q2PPJ7³, ENSP00000202677⁴	I2D: score=1 STRING: ENSP00000202677
SRC	P12931³, ENSP00000350941⁴	I2D: score=1 STRING: ENSP00000350941
ITSN2	Q9NZM3³	I2D: score=1
RALA	ENSP00000005257⁴	STRING: ENSP00000005257
AKT2	ENSP00000375892⁴	STRING: ENSP00000375892

About this table

Gene Ontology (GO): Selected biological process terms (see all 6): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0032484	Ral protein signal transduction	IEA	--
GO:0032859	activation of Ral GTPase activity	ISS	--
GO:0032880	regulation of protein localization	--	--
GO:0051056	regulation of small GTPase mediated signal transduction	--	--
GO:0060178	regulation of exocyst localization	IEA	--

Find genes that share ontologies with RALGAPB About GenesLikeMe

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, Sets of similar genes according to GenesLikeMe)
About This Section

Browse Small Molecules at EMD Millipore

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Browse Tocris compounds for RALGAPB (RLGPB)

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
About This Section

REFSEQ mRNAs for RALGAPB gene (7 alternative transcripts):

NM_001282917.1 NM_001282918.1 NM_020336.3 XM_005260462.1 XM_005260463.1 XM_005260464.1 XM_005260465.1

Unigene Cluster for RALGAPB:

Ral GTPase activating protein, beta subunit (non-catalytic)

Hs.598850 [show with all ESTs]

Unigene Representative Sequence: NM_020336

10 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000262879 ENST00000397042 ENST00000397040(uc002xiy.1) ENST00000495949

ENST00000438490 ENST00000461423(uc002xja.1) ENST00000461147 ENST00000490114

ENST00000537204 ENST00000397038(uc010zvz.1 uc002xiw.3 uc002xix.3 uc002xiz.3)

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Additional mRNA sequence:

AB621815.1 AK026771.1 AK123576.1 AK125260.1 AK125916.1 AK304242.1 AL132998.1 AL834436.1

BC010916.1 BC018668.1 BC036425.2 BC047482.1 BX641080.1 CR936800.1

17 DOTS entries:

DT.92435970 DT.91963351 DT.453174 DT.97784304 DT.91984412 DT.100724159 DT.40280902 DT.99991846

DT.100703905 DT.120814111 DT.120814140 DT.40123374 DT.92435969 DT.95275801 DT.120814108 DT.92435967

DT.99963796

Selected AceView cDNA sequences (see all 292):

AI017681 AA180094 AL132998 CK904744 AW473729 AW674286 BE673632 BE669526

BM727700 AA495863 AL834436 AI281190 AI767925 BM997147 AA828530 BC018668

BF198044 BQ930118 BE550337 BC047482 AI359832 AA889796 BX375121 BM069766

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for RALGAPB About this scheme

ExUns:	1a	·	1b	^	2	^	3	^	4a	·	4b	^	5	^	6a	·	6b	^	7	^	8	^	9	^	10	^	11	^	12	^	13	^	14	^	15	^	16a	·	16b	^	17	^	18	^	19a	·	19b	^	20	^	21	^
SP1:																																					-										-
SP2:																																															-
SP3:																																															-
SP4:
SP5:

ExUns:	22	^	23	^	24	^	25	^	26	^	27a	·	27b	^	28	^	29	^	30a	·	30b
SP1:											-
SP2:											-
SP3:											-
SP4:
SP5:

ECgene alternative splicing isoforms for RALGAPB

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GenesLikeMe, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

RALGAPB expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: ATTTTTTCTT

About this image

RALGAPB expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database


Eye (Sensory Organs)
Retina

RALGAPB Protein expression data from MOPED¹, PaxDb² and MaxQB³:

About this image

RALGAPB Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.598850

UniProtKB/Swiss-Prot: RLGPB_HUMAN, Q86X10

Tissue specificity: Highly expressed in brain, mostly in amygdala

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In Situ
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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for RALGAPB gene from Selected species (see all 16) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Ralgapb^{1 , 5}	Ral GTPase activating protein, beta subunit (non-catalytic)^{1, 5}	92.55(n)¹ 97.38(a)¹		2 (78.72 cM)⁵ 228850¹ NM_177658.3¹ NP_808326.2¹ 158409848⁵
chicken (Gallus gallus)	Aves	RALGAPB¹	Ral GTPase activating protein, beta subunit (non-catalytic)	81.92(n) 92.2(a)		419128 NM_001030846.1 NP_001026017.1
lizard (Anolis carolinensis)	Reptilia	RALGAPB⁶	Ral GTPase activating protein, beta subunit (non-c...	88(a)	1 ↔ 1	4(134780928-134841256)
African clawed frog (Xenopus laevis)	Amphibia	Xl.16058²	Xenopus laevis transcribed sequence with weak similarity more	75.75(n)		BJ071291.1
zebrafish (Danio rerio)	Actinopterygii	ralgapb¹	Ral GTPase activating protein, beta subunit (non-catalytic)	69.31(n) 79.36(a)		559303 XM_002662565.3 XP_002662611.2
fruit fly (Drosophila melanogaster)	Insecta	CG34408¹	CG34408	50.64(n) 46.54(a)		31953 NM_132385.2 NP_572613.2
worm (Caenorhabditis elegans)	Secernentea	D2085.5¹	D2085.5	40.9(n) 28.48(a)		3564922 NM_001026883.1 NP_001022054.1

ENSEMBL Gene Tree for RALGAPB (if available)
TreeFam Gene Tree for RALGAPB (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68,Sets of similar genes according to GenesLikeMe)
About This Section

Paralogs for RALGAPB gene

1 SIMAP similar gene for RALGAPB using alignment to 5 protein entries: RLGPB_HUMAN (see all proteins):

DKFZp686N19168

Find genes that share paralogs with RALGAPB About GenesLikeMe

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section

SNP ID	Valid	Clinical significance	Chr 20 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs147786820^1,2	C,F	untested¹	37161494(+)	`CTTAAA/G/TAGATT`	2	K R	mis¹		1		NA	4548
rs6099824^1,2	C,F,A,H	--	37099824(+)	`GCTTTG/TGGACA`	1	--	us2k¹		13		NS NA CSA WA	1274
rs140961426^1,2		--	37100026(+)	`AGTACA/TGGGTT`	1	--	us2k¹		0	--	--	--	--
rs6099828^1,2	C,F,A,H	--	37100072(+)	`CTCCTG/TTCTTT`	1	--	us2k¹		7		NS EA CSA WA	538
rs7509230^1,2	H	--	37100097(+)	`TCAGCA/GCAGCC`	1	--	us2k¹		4		NS EA	420
rs113003724^1,2	F	--	37100145(+)	`TACCCT/AGTTCC`	1	--	us2k¹		1		CSA	2
rs111361016^1,2	C	--	37100188(+)	`AACTTC/TTCCAA`	1	--	us2k¹		2		CSA WA	120
rs1609994^1,2	C,F,A,H	--	37100214(+)	`AAGGTC/TTCCTT`	1	--	us2k¹ tfbs³		20		NS EA NA	2332
rs138564818^1,2		--	37100315(+)	`TCAGCC/TCCTGT`	1	--	us2k¹		0	--	--	--	--
rs6025891^1,2	C,F	--	37100372(+)	`AACTAC/AATAAT`	1	--	us2k¹		1		WA	118

HapMap Linkage Disequilibrium report for RALGAPB (37101459 - 37207504 bp)

Structural Variations
Database of Genomic Variants (DGV) 7 variations for RALGAPB: About this table

Variant ID	Type	Subtype	PubMed ID
esv2359941	CNV	Deletion	18987734
esv2722399	CNV	Deletion	23290073
esv2581563	CNV	Deletion	19546169
esv2624452	CNV	Deletion	19546169
nsv509769	CNV	Insertion	20534489
nsv179180	CNV	Loss	16902084
dgv1327e1	CNV	Complex	17122850

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB, Sets of similar genes according to GenesLikeMe)
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(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for RALGAPB gene, integrated from 10 sources (see all 19):
(articles sorted by number of sources associating them with RALGAPB)

Tuberous sclerosis tumor suppressor complex-like complexes act as GTPase-activating proteins for Ral GTPases. (PubMed id 19520869)^{1, 3} Shirakawa R.... Horiuchi H. (J. Biol. Chem. 2009)
Adipocytes contain a novel complex similar to the tuberous sclerosis complex. (PubMed id 16490346)^{1, 2} Gridley S.... Lienhard G.E. (Cell. Signal. 2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S.... Malek J. (Genome Res. 2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (Nat. Genet. 2004)
Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)^{1, 2} Nakajima D.... Nagase T. (DNA Res. 2002)
The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)^{1, 2} Deloukas P....Rogers J. (Nature 2001)
Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10574462)^{1, 2} Nagase T.... Ohara O. (DNA Res. 1999)
Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)¹ Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. (PubMed id 24255178)¹ Couzens A.L....Gingras A.C. (Sci Signal 2013)
Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method. (PubMed id 21697133)¹ Oshikawa M.... Kato S. (Invest. Ophthalmol. Vis. Sci. 2011)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 57148	HGNC: 29221	AceView: KIAA1219	Ensembl:ENSG00000170471	euGenes: HUgn57148
ECgene: RALGAPB	H-InvDB: RALGAPB

(According to HUGE)
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HUGE: KIAA1219

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for RALGAPB	Pharmacogenomics, SNPs, Pathways

Intellectual Property for RALGAPB gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for RALGAPB gene:
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RALGAPB Gene

Ral GTPase Activating Protein, Beta Subunit (Non-Catalytic)

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RALGAPB Gene

Ral GTPase Activating Protein, Beta Subunit (Non-Catalytic)

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