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RALGAPB Gene

protein-coding   GIFtS: 50
GCID: GC20P037102

Ral GTPase Activating Protein, Beta Subunit (Non-Catalytic)

(Previous name: KIAA1219)
(Previous symbol: KIAA1219)
  Search for RALGAPB
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ral GTPase Activating Protein, Beta Subunit (Non-Catalytic)1 2
KIAA12191 2 3
RalGAPbeta2
Ral GTPase-Activating Protein Subunit Beta2
p1703

External Ids:    HGNC: 292211   Entrez Gene: 571482   Ensembl: ENSG000001704717   UniProtKB: Q86X103   

Export aliases for RALGAPB gene to outside databases

Previous GC identifers: GC20P036535 GC20P033838


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RALGAPB Gene:
RALGAPB (Ral GTPase activating protein, beta subunit (non-catalytic)) is a protein-coding gene. GO annotations related to this gene include protein heterodimerization activity and Ral GTPase activator activity.

UniProtKB/Swiss-Prot: RLGPB_HUMAN, Q86X10
Function: Non-catalytic subunit of the heterodimeric RalGAP1 and RalGAP2 complexes which act as GTPase activators
for the Ras-like small GTPases RALA and RALB (By similarity)

Gene Wiki entry for RALGAPB (KIAA1219) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000020.10  NT_011362.11  NC_018931.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for RALGAPB
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for RALGAPB

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RALGAPB


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q11.23   Ensembl cytogenetic band:  20q11.23   HGNC cytogenetic band: 20q11.23

RALGAPB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RALGAPB gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P037102:  view genomic region     (about GC identifiers)

Start:
37,101,459 bp from pter      End:
37,207,504 bp from pter
Size:
106,046 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RLGPB_HUMAN, Q86X10 (See protein sequence)
Recommended Name: Ral GTPase-activating protein subunit beta  
Size: 1494 amino acids; 166799 Da
Subunit: Component of the heterodimeric RalGAP1 complex with RALGAPA1 and of the heterodimeric RalGAP2 complex
with RALGAPA2. Heterodimerization is required for activity (By similarity)
Sequence caution: Sequence=BAA86533.3; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=BAC85649.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=CAB61346.1;
Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=CAD39096.1; Type=Erroneous
initiation; Note=Translation N-terminally shortened;
Secondary accessions: A2A2E8 Q5TG31 Q8N3D1 Q8WWC0 Q9H3X8 Q9UJR1 Q9ULK1 Q9Y3G9
Alternative splicing: 4 isoforms:  Q86X10-1   Q86X10-2   Q86X10-3   Q86X10-4   (Splicing acceptor site is not canonical. No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RALGAPB: NX_Q86X10

Explore proteomics data for RALGAPB at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RALGAPB Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001269846.1  NP_001269847.1  NP_065069.1  

    ENSEMBL proteins: 
     ENSP00000262879   ENSP00000380235   ENSP00000380233   ENSP00000416646   ENSP00000442959  
     ENSP00000380231  
    Reactome Protein details: Q86X10

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR000331 Rap_GAP_dom

    Graphical View of Domain Structure for InterPro Entry Q86X10

    ProtoNet protein and cluster: Q86X10

    1 Blocks protein domain: IPB000331 Rap/ran-GAP

    UniProtKB/Swiss-Prot: RLGPB_HUMAN, Q86X10
    Similarity: Contains 1 Rap-GAP domain


    Find genes that share domains with RALGAPB           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RLGPB_HUMAN, Q86X10
    Function: Non-catalytic subunit of the heterodimeric RalGAP1 and RalGAP2 complexes which act as GTPase activators
    for the Ras-like small GTPases RALA and RALB (By similarity)

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005096GTPase activator activity ----
    GO:0005488binding ----
    GO:0017123Ral GTPase activator activity ISS--
    GO:0046982protein heterodimerization activity ISS--
         
    Find genes that share ontologies with RALGAPB           About GenesLikeMe


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Ralgapb):
     mortality/aging 

    Find genes that share phenotypes with RALGAPB           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RALGAPB
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    hsa-miR-26a-2* hsa-miR-642a hsa-miR-485-3p hsa-miR-1245 hsa-miR-30d hsa-miR-219-5p hsa-miR-30a hsa-miR-629*
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    mitochondrion1
    nucleus1
    peroxisome1
    plasma membrane1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RALGAPB About    
    See pathways by source

    SuperPathContained pathways About
    1Clathrin derived vesicle budding
    Membrane Trafficking0.32
    Translocation of GLUT4 to the Plasma Membrane0.32


    Find genes that share SuperPaths with RALGAPB           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for RALGAPB
        Translocation of GLUT4 to the plasma membrane


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RALGAPB
    Interactions:

        Search GeneGlobe Interaction Network for RALGAPB

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    Selected Interacting proteins for RALGAPB (Q86X103 ENSP000002628794) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RALGAPA2Q2PPJ73, ENSP000002026774I2D: score=1 STRING: ENSP00000202677
    SRCP129313, ENSP000003509414I2D: score=1 STRING: ENSP00000350941
    ITSN2Q9NZM33I2D: score=1 
    RALAENSP000000052574STRING: ENSP00000005257
    AKT2ENSP000003758924STRING: ENSP00000375892
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0032484Ral protein signal transduction IEA--
    GO:0032859activation of Ral GTPase activity ISS--
    GO:0032880regulation of protein localization ----
    GO:0051056regulation of small GTPase mediated signal transduction ----
    GO:0060178regulation of exocyst localization IEA--

    Find genes that share ontologies with RALGAPB           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RALGAPB (RLGPB)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RALGAPB gene (3 alternative transcripts): 
    NM_001282917.1  NM_001282918.1  NM_020336.3  

    Unigene Cluster for RALGAPB:

    Ral GTPase activating protein, beta subunit (non-catalytic)
    Hs.598850  [show with all ESTs]
    Unigene Representative Sequence: NM_020336
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000262879 ENST00000397042 ENST00000397040(uc002xiy.1) ENST00000495949
    ENST00000438490 ENST00000461423(uc002xja.1) ENST00000461147 ENST00000490114
    ENST00000537204 ENST00000397038(uc010zvz.1 uc002xiw.3 uc002xix.3 uc002xiz.3)

    miRNA
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    hsa-miR-26a-2* hsa-miR-642a hsa-miR-485-3p hsa-miR-1245 hsa-miR-30d hsa-miR-219-5p hsa-miR-30a hsa-miR-629*
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    Additional mRNA sequence: 

    AB621815.1 AK026771.1 AK123576.1 AK125260.1 AK125916.1 AK304242.1 AL132998.1 AL834436.1 
    BC010916.1 BC018668.1 BC036425.2 BC047482.1 BX641080.1 CR936800.1 

    17 DOTS entries:

    DT.92435970  DT.91963351  DT.453174  DT.97784304  DT.91984412  DT.100724159  DT.40280902  DT.99991846 
    DT.100703905  DT.120814111  DT.120814140  DT.40123374  DT.92435969  DT.95275801  DT.120814108  DT.92435967 
    DT.99963796 

    Selected AceView cDNA sequences (see all 292):

    AI017681 AA180094 AL132998 CK904744 AW473729 AW674286 BE673632 BE669526 
    BM727700 AA495863 AL834436 AI281190 AI767925 BM997147 AA828530 BC018668 
    BF198044 BQ930118 BE550337 BC047482 AI359832 AA889796 BX375121 BM069766 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for RALGAPB    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16a · 16b ^ 17 ^ 18 ^ 19a · 19b ^ 20 ^ 21 ^
    SP1:                                                                                                              -                             -               
    SP2:                                                                                                                                            -               
    SP3:                                                                                                                                            -               
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 22 ^ 23 ^ 24 ^ 25 ^ 26 ^ 27a · 27b ^ 28 ^ 29 ^ 30a · 30b
    SP1:                                -                                 
    SP2:                                -                                 
    SP3:                                -                                 
    SP4:                                                                  
    SP5:                                                                  


    ECgene alternative splicing isoforms for RALGAPB

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RALGAPB expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATTTTTTCTT
    RALGAPB Expression
    About this image


    RALGAPB expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Eye (Sensory Organs)
             Retina
    RALGAPB Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RALGAPB Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.598850

    UniProtKB/Swiss-Prot: RLGPB_HUMAN, Q86X10
    Tissue specificity: Highly expressed in brain, mostly in amygdala

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for RALGAPB gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ralgapb1 , 5 Ral GTPase activating protein, beta subunit (non-catalytic)1, 5 92.55(n)1
    97.38(a)1
      2 (78.72 cM)5
    2288501  NM_177658.31  NP_808326.21 
     1584098485 
    chicken
    (Gallus gallus)
    Aves RALGAPB1 Ral GTPase activating protein, beta subunit (non-catalytic) 81.92(n)
    92.2(a)
      419128  NM_001030846.1  NP_001026017.1 
    lizard
    (Anolis carolinensis)
    Reptilia RALGAPB6
    Ral GTPase activating protein, beta subunit (non-c...
    88(a)
    1 ↔ 1
    4(134780928-134841256)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.160582 Xenopus laevis transcribed sequence with weak similarity more 75.75(n)    BJ071291.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ralgapb1 Ral GTPase activating protein, beta subunit (non-catalytic) 69.31(n)
    79.36(a)
      559303  XM_002662565.3  XP_002662611.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG344081 CG34408 50.64(n)
    46.54(a)
      31953  NM_132385.2  NP_572613.2 
    worm
    (Caenorhabditis elegans)
    Secernentea D2085.51 D2085.5 40.9(n)
    28.48(a)
      3564922  NM_001026883.1  NP_001022054.1 


    ENSEMBL Gene Tree for RALGAPB (if available)
    TreeFam Gene Tree for RALGAPB (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RALGAPB gene
    1 SIMAP similar gene for RALGAPB using alignment to 5 protein entries:     RLGPB_HUMAN (see all proteins):
    DKFZp686N19168

    Find genes that share paralogs with RALGAPB           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RALGAPB (see all 2053)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1477868201,2
    C,Funtested137161494(+) CTTAAA/G/TAGATT 2 K R mis11NA 4548
    rs60998241,2
    C,F,A,H--37099824(+) GCTTTG/TGGACA 1 -- us2k113Minor allele frequency- T:0.19NS NA CSA WA 1274
    rs1409614261,2
    --37100026(+) AGTACA/TGGGTT 1 -- us2k10--------
    rs60998281,2
    C,F,A,H--37100072(+) CTCCTG/TTCTTT 1 -- us2k17Minor allele frequency- T:0.12NS EA CSA WA 538
    rs75092301,2
    H--37100097(+) TCAGCA/GCAGCC 1 -- us2k14Minor allele frequency- G:0.00NS EA 420
    rs1130037241,2
    F--37100145(+) TACCCT/AGTTCC 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs1113610161,2
    C--37100188(+) AACTTC/TTCCAA 1 -- us2k12Minor allele frequency- T:0.03CSA WA 120
    rs16099941,2
    C,F,A,H--37100214(+) AAGGTC/TTCCTT 1 -- us2k1 tfbs320Minor allele frequency- T:0.11NS EA NA 2332
    rs1385648181,2
    --37100315(+) TCAGCC/TCCTGT 1 -- us2k10--------
    rs60258911,2
    C,F--37100372(+) AACTAC/AATAAT 1 -- us2k11Minor allele frequency- A:0.03WA 118

    HapMap Linkage Disequilibrium report for RALGAPB (37101459 - 37207504 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for RALGAPB:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2359941CNV Deletion18987734
    esv2722399CNV Deletion23290073
    esv2581563CNV Deletion19546169
    esv2624452CNV Deletion19546169
    nsv509769CNV Insertion20534489
    nsv179180CNV Loss16902084
    dgv1327e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RALGAPB
    DNA2.0 Custom Variant and Variant Library Synthesis for RALGAPB

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RALGAPB gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with RALGAPB)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Tuberous sclerosis tumor suppressor complex-like complexes act as GTPase-activating proteins for Ral GTPases. (PubMed id 19520869)1, 3 Shirakawa R.... Horiuchi H. (J. Biol. Chem. 2009)
    2. Adipocytes contain a novel complex similar to the tuberous sclerosis complex. (PubMed id 16490346)1, 2 Gridley S.... Lienhard G.E. (Cell. Signal. 2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (DNA Res. 2002)
    6. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (Nature 2001)
    7. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10574462)1, 2 Nagase T.... Ohara O. (DNA Res. 1999)
    8. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    9. Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. (PubMed id 24255178)1 Couzens A.L....Gingras A.C. (Sci Signal 2013)
    10. Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method. (PubMed id 21697133)1 Oshikawa M.... Kato S. (Invest. Ophthalmol. Vis. Sci. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 57148 HGNC: 29221 AceView: KIAA1219 Ensembl:ENSG00000170471 euGenes: HUgn57148
    ECgene: RALGAPB H-InvDB: RALGAPB

    (According to HUGE)
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    HUGE: KIAA1219

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RALGAPB Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RALGAPB gene:
    Search GeneIP for patents involving RALGAPB

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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