Aliases for RALGAPA1 Gene
External Ids for RALGAPA1 Gene
Previous HGNC Symbols for RALGAPA1 Gene
Previous GeneCards Identifiers for RALGAPA1 Gene
This gene encodes a major subunit of the RAL-GTPase activating protein. A similar protein in mouse binds E12, a transcriptional regulator of immunoglobulin genes. The mouse protein also functions in skeletal muscle by binding to the regulatory 14-3-3 proteins upon stimulation with insulin or muscle contraction. A pseudogene of this gene has been identified on chromosome 9. [provided by RefSeq, Oct 2016]
GeneCards Summary for RALGAPA1 Gene
RALGAPA1 (Ral GTPase Activating Protein Catalytic Alpha Subunit 1) is a Protein Coding gene. Among its related pathways are Integrated Breast Cancer Pathway. GO annotations related to this gene include protein heterodimerization activity and GTPase activator activity. An important paralog of this gene is RALGAPA2.
UniProtKB/Swiss-Prot for RALGAPA1 Gene
Catalytic subunit of the heterodimeric RalGAP1 complex which acts as a GTPase activator for the Ras-like small GTPases RALA and RALB.