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RALA Gene

protein-coding GIFtS: 66

GC07P039630

v-ral simian leukemia viral oncogene homolog A (ras related)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: RAL)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
MGC48949 ^²
RAL ^², ³

Descriptions
RAS-like protein A ^²
Ras family small GTP binding protein RALA ^²
Ras-related protein Ral-A ^²
ras related v-ral simian leukemia viral oncogene homolog A ^²
v-ral simian leukemia viral oncogene homolog A (ras related) ^²

External Ids
HGNC: 9839¹
Entrez Gene: 5898²
UniProtKB: P11233³
Ensembl: ENSG00000006451⁷

Search outside databases for aliases for RALA gene

Previous GC identifers: GC07P039372 GC07P039403 GC07P039436

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for RALA:

The product of this gene belongs to the small GTPase superfamily, Ras family of proteins.

GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain

cell surface receptors. This gene encodes a low molecular mass ras-like GTP-binding protein that

shares about 50% similarity with other ras proteins. [provided by RefSeq]

Gene Wiki entry for RALA

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the RALA gene

Entrez Gene cytogenetic band: 7p15-p13 Ensembl cytogenetic band: 7p14.1 HGNC cytogenetic band: 7p22-p15

RALA Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07P039630: (about GC identifiers)

Start:	39,629,687 bp from pter
End:	39,714,244 bp from pter
Size:	84,558 bases
Orientation:	plus strand

1 alternative location:

Chr7+,CRA_TCAG 39,701,024-39,785,592

RefSeq DNA sequence:

NC_000007.12 NT_007819.16 NT_079592.2

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: RALA_HUMAN, P11233 (See protein sequence)

Recommended Name: Ras-related protein Ral-A precursor

Size: 206 amino acids; 23567 Da

Subunit: Interacts with RALBP1 via its effector domain. Interacts with EXOC8 and EXOC2. EXOC2 and

EXOC8 have overlapping binding sites and compete for RALA binding. Interacts with Clostridium

exoenzyme C3. Interacts with RALGPS1

Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential)

PDB structures from and Proteopedia :

1UAD (3D)

1ZC3 (3D)

1ZC4 (3D)

2A78 (3D)

2A9K (3D)

2BOV (3D)

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_005393.2

ENSEMBL proteins:

ENSP00000005257

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (RALA+RALB, RALA)
	Human Recombinant Proteins from Abnova (RALA)

OriGene Purified Recombinant Human Protein: RALA

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	IEA	--
GO:0005886	plasma membrane	IEA	--

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Antibodies for RALA:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibody Arrays and Antibodies for RALA
	R&D Systems Antibodies for RALA
	Cell Signaling Technology (CST) Antibodies for RALA
	Antibodies from Abcam (RALA+RALB, RALA), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (RALA)
	Novus Biologicals Antibodies for RALA

Assays for RALA:

	Browse Invitrogen for biochemical assays
	Millipore Kits and Assays for the Analysis of RALA
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P11233

ProtoNet protein and cluster: P11233

2 Blocks protein families:

IPB001806 Transforming protein P21 RAS signature

IPB003577 Ras small GTPase

UniProtKB/Swiss-Prot: RALA_HUMAN, P11233

Similarity: Belongs to the small GTPase superfamily. Ras family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (RALA)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_005402

Applied Biosystems Silencer® siRNAs for RALA

Sigma-Aldrich siRNA for RALA

Sigma-Aldrich shRNA for RALA

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for RALA
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_005402
Myc/DDK tagged cDNA clone in CMV expression vector: NM_005402
untagged cDNA clone in CMV expression vector: NM_005402

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_005402

Genatlas biochemistry entry for RALA:

simian leukemia viral (v-ral) oncogene homolog A,Ras oncogene superfamily member

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	nucleotide binding	IEA	--
GO:0005515	protein binding	IPI	7673236
GO:0005525	GTP binding	TAS	2550440

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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2 Sigma-Aldrich "Your Favorite Gene" Pathways for RALA (Your Favorite Gene powered by Ingenuity)

Molecular Mechanisms of Cancer
Integrin Signaling

GeneDecks RALA for the pathways selected above

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Gene Network Central^TM Interacting Genes and Proteins Network for RALA

5/45 Interacting proteins for RALA (P11233^{1, 2} ENSP00000005257³) via UniProtKB, MINT, and/or STRING (see all 45 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CALM3	P62158², ENSP00000291295³	MINT-15764 MINT-15765 MINT-15766 STRING (score=.986)
PPP2R1B	P30154¹	EBI-1036803, EBI-357094
C3 C3 (xeno)	P15879¹	EBI-1036803, EBI-1042083
CALM1	P62158²	MINT-15764 MINT-15765 MINT-15766
CALM2	P62158²	MINT-15764 MINT-15765 MINT-15766

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5 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006935	chemotaxis	TAS	10848592
GO:0007265	Ras protein signal transduction	EXP	11520933
GO:0031532	actin cytoskeleton reorganization	IDA	10051605
GO:0044419	interspecies interaction between organisms	IEA	--
GO:0051491	positive regulation of filopodium formation	IDA	10051605

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for RALA
8 Novoseek chemical compound relationships for RALA gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
gdp	62.70	22	8702675 (3), 9053849 (2), 1379346 (1), 8524240 (1) (see all 9)
gtp	57.83	22	17202486 (4), 11322487 (3), 8702675 (2), 1379346 (1) (see all 7)
geranylgeranyl pyrophosphate	50.64	3	8972729 (1), 16125679 (1)
phosphatidylinositol	21.02	3	15263068 (1), 10419502 (1), 15208305 (1)
tyrosine	5.83	3	12866021 (1), 9550702 (1), 7477381 (1)
oxygen	0.00	1	16964283 (1)
phospholipid	0.00	2	15980073 (1)
calcium	0.00	29	11322487 (4), 12034722 (4), 9566869 (2), 10419502 (1) (see all 5)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (RALA)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_005402

Sigma-Aldrich siRNA for RALA

Sigma-Aldrich shRNA for RALA

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_005402

REFSEQ mRNAs for RALA gene:

NM_005402.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_005402

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_005402
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_005402
                                 untagged cDNA clone in CMV expression vector: NM_005402

Additional cDNA sequence:

AF086082.1 AF493910.1 AK026850.1 AK308109.1 BC039858.1 CR600160.1 M29893.1 X15014.1

13 DOTS entries:

DT.80100564 DT.100785246 DT.100656840 DT.91757843 DT.95294309 DT.121073355 DT.121073398 DT.95294307

DT.95294311 DT.100785247 DT.121073387 DT.91757845 DT.95294312

24/275 AceView cDNA sequences (see all 275 ):

AF086082 BQ068256 CA444080 BM821639 X15014 BE673391 F11825 BE784233

BM806998 NM_005402 BM550259 AA382990 BM992487 BU630853 AW474027 BF115263

AI283900 BI770485 AA379902 BU743277 F10291 AU132473 AI214262 F12680

highest scoring ESTs for RALA:

M29893 AA045015 AA083480 AA296743 AA368261 AA371289 AA379902 AA379961 AA382990 AA382991

Unigene Cluster for RALA:

V-ral simian leukemia viral oncogene homolog A (ras related)

Hs.6906 [show with all ESTs]

Unigene Representative Sequence: NM_005402

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000005257

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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RALA expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for RALA

¹ / ² / ³

8 probe-sets matching RALA gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
46237_at²^{, 3}	U95-B	1	1.00	1.00	0.85	1.43	AW001342	0.80	1.00	0.91	1
1876_at²^{, 3}	U95-A	3	1.00	0.88	0.91	0.59	HG1103-HT1103	0.20	1.00	0.72	1
39253_s_at²^{, 3}	U95-A	3	1.00	0.57	0.90	0.99	M29893	1.00	1.00	1.00	1
1877_g_at²^{, 3}	U95-A	3	1.00	0.56	0.93	1.01	HG1103-HT1103	0.20	1.00	0.72	1
224880_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AV703462	0.60	1.00	0.82	1
214435_x_at²^{, 3}	U133-A	3	1.00	0.59	--	--	NM_005402	0.60	1.00	0.82	1
224880_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
214435_x_at²	U133Plus2	3	1.00	0.59	--	--	--	--	--	--	--

GeneDecks RALA for binary patterns associated with the probe-sets selected above

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TGTACTTATT

SOURCE GeneReport for Unigene cluster: Hs.6906
Expression variation in blood from EXPOLDB for RALA

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for RALA gene from 5/12 species (see all 12 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	RALA¹	--	v-ral simian leukemia viral oncogene homolog A (ras more	95.63(n) 99.03(a)	475875 XM_851294.1 XP_856387.1
chimpanzee (Pan troglodytes)	RALA¹	--	v-ral simian leukemia viral oncogene homolog A (ras more	99.68(n) 100(a)	737424 XM_001140368.1 XP_001140368.1
cow (Bos taurus)	RALA¹	--	v-ral simian leukemia viral oncogene homolog A (ras more	91.91(n) 99.03(a)	538477 NM_001034644.1 NP_001029816.1
rat (Rattus norvegicus)	Rala¹	--	v-ral simian leukemia viral oncogene homolog A (ras more	93.53(n) 99.51(a)	81757 NM_031093.2 NP_112355.1
mouse (Mus musculus)	Rala^{1, 5}	13 (10.00 cM)⁵	v-ral simian leukemia viral oncogene homolog A (ras more^{1, 5}	92.72(n)¹ 99.51(a)¹	56044¹ NM_019491.5¹ NP_062364.3¹ AA212148⁵ AA833038⁵ (see all 14)

About this table Species with no ortholog for RALA

ENSEMBL Gene Tree for RALA

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for RALA gene

RALB²

Pseudogenes

1 related pseudogene

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/342 NCBI SNPs in RALA are shown (see all 342 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 89)

AB	SNP ID	Valid	Chr 7 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs10254562^1,2	A,C,F,H	39628049(+)	`ATGGTC/AATCTA`	1	--	ng5¹		6	EU EA WA NA	594
--	rs4723892^1,2	A,C,F,H	39712991(+)	`ATATCC/TGGTTA`	1	--	ut3¹ ese³		5	EU WA NA	368
	rs10486805^1,2	C,F,H	39714450(+)	`ACATTG/CAAGAT`	1	--	ng3¹		16	NS NA EU EA WA	1024
	rs2008819^1,2	C,F,H	39628793(-)	`AGAATG/AGATAG`	1	--	ng5¹		15	NA NS EU EA WA	1108
	rs10486804^1,2	C,F,H	39714430(+)	`GGAAGG/AACTCG`	1	--	ng3¹		12	NS EU EA WA NA	666
	rs17508585^1,2	C,F,H	39714641(+)	`ATGTCT/CGGAGG`	1	--	ng3¹		11	NA EU EA WA	978
	rs3944115^1,2	H	39628555(-)	`CTTGGT/GGAGGC`	1	--	ng5¹ tfbs³		1	EU	120
	rs2107710^1,2	A,C,F,H,O	39662398(-)	`ATACTT/CTGGCC`	1	--	int¹		7	EU EA WA NA	550
	rs2329464^1,2	A,C,F,H,O	39677150(+)	`TTCTCA/GCTTTC`	1	--	int¹		4	EU EA WA	406
--	rs1034771^1,2	A,C,F,H,O	39687268(-)	`TGCATG/AACAAT`	1	--	int¹		9	MN EU EA WA	1020

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HapMap Linkage Disequilibrium images for RALA (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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OMIM: 179550

10 Novoseek disease relationships for RALA gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
bladder carcinoma	24.30	1	16488989 (1)
pancreatic carcinoma	21.34	2	17174914 (1), 16757353 (1)
bladder cancer	15.73	12	17606711 (6), 17496927 (2)
cancer	14.70	11	16103060 (3), 15953551 (1), 17875936 (1), 17496927 (1) (see all 8)
prostate carcinoma	11.37	1	16964283 (1)
pheochromocytoma	9.28	3	17202486 (1), 17344481 (1)
pancreatic cancer	2.88	5	17174914 (3), 15950903 (1)
breast cancer	0.00	2	12386818 (1), 10896938 (1)
tumors	0.00	15	10467419 (2), 17174914 (1), 17606711 (1), 15950903 (1) (see all 8)
metastasis	0.00	4	17174914 (1), 17606711 (1), 16103060 (1)

About this table

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/142 PubMed articles for RALA gene (see all 142 ):

Ral GTPases regulate exocyst assembly through dual subunit interactions. (PubMed id 14525976)^{1, 3, 4} Moskalenko S.... White M.A. (2003)
Molecular recognition of an ADP-ribosylating Clostridium botulinum C3 exoenzyme by RalA GTPase. (PubMed id 15809419)^{3, 4} Holbourn K.P.... Acharya K.R. (2005)
Exo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase. (PubMed id 15920473)^{3, 4} Jin R....Brunger A.T. (2005)
Crystal structure of the C3bot-RalA complex reveals a novel type of action of a bacterial exoenzyme. (PubMed id 16177825)^{3, 4} Pautsch A.... Aktories K. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
The DNA sequence of human chromosome 7. (PubMed id 12853948)^{3, 4} Hillier L.W.... Wilson R.K. (2003)
Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity. (PubMed id 7673236)^{3, 4} Jullien-Flores V.... Camonis J.H. (1995)
Carboxyl-terminal isoprenylation of ras-related GTP-binding proteins encoded by rac1, rac2, and ralA. (PubMed id 1903399)^{3, 4} Kinsella B.T.... Maltese W.A. (1991)
Coding sequences of human ralA and ralB cDNAs. (PubMed id 2662142)^{3, 4} Chardin P. and Tavitian A. (1989)
Identification of the ral and rac1 gene products, low molecular mass GTP-binding proteins from human platelets. (PubMed id 2550440)^{3, 4} Polakis P.G....Snyderman R. (1989)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 5898	HGNC: 9839	AceView: RALA	Ensembl:ENSG00000006451	euGenes: HUgn5898
ECgene: RALA	H-InvDB: RALA

(According to HUGE)
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(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
ATLAS Chromosomes in Cancer entry for RALA	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for RALA
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for RALA:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for RALA-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for RALA		Antibodies for RALA
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for RALA		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (RALA)
	Antibodies (RALA)
	Search for Chimera RNAi
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Antibodies & Assays for RALA

	Recombinant Proteins (RALA+RALB, RALA)
	Antibodies (RALA+RALB, RALA)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for RALA

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for RALA

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RALA Gene

protein-coding GIFtS: 66

Aliases &
Descriptions
for RALA

Summaries
for RALA

Genomic Location
for RALA

Proteins
for RALA

Protein Domains/
Families
for RALA

Gene Function
for RALA

Pathways & Interactions
for RALA

Drugs & Compounds
for RALA

Transcripts
for RALA

Expression
for RALA

Orthologs
for RALA

Paralogs
for RALA

SNPs/Variants
for RALA

Disorders & Mutations
for RALA

Medical News
for RALA

Publications
for RALA

Search for RALA

Genome Databases showing RALA

Other Databases showing RALA

Specialized Databases showing RALA

Licensable Technologies
for RALA

Services
for RALA

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

RALA Gene

protein-coding GIFtS: 66

Aliases & Descriptionsfor RALA

Summariesfor RALA

Genomic Locationfor RALA

Proteinsfor RALA

Protein Domains/Familiesfor RALA

Gene Functionfor RALA

Pathways & Interactionsfor RALA

Drugs & Compoundsfor RALA

Transcriptsfor RALA

Expression for RALA

Orthologsfor RALA

Paralogsfor RALA

SNPs/Variantsfor RALA

Disorders & Mutationsfor RALA

Medical Newsfor RALA

Publicationsfor RALA

Search for RALA

Genome Databases showing RALA

Other Databases showing RALA

Specialized Databases showing RALA

Licensable Technologiesfor RALA

Servicesfor RALA

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for RALA

Summaries
for RALA

Genomic Location
for RALA

Proteins
for RALA

Protein Domains/
Families
for RALA

Gene Function
for RALA

Pathways & Interactions
for RALA

Drugs & Compounds
for RALA

Transcripts
for RALA

Expression
for RALA

Orthologs
for RALA

Paralogs
for RALA

SNPs/Variants
for RALA

Disorders & Mutations
for RALA

Medical News
for RALA

Publications
for RALA

Licensable Technologies
for RALA

Services
for RALA