Aliases for RAET1G Gene
External Ids for RAET1G Gene
Previous GeneCards Identifiers for RAET1G Gene
Members of the RAET1 family, such as RAET1G, are major histocompatibility complex (MHC) class I-related genes located within a 180-kb cluster on chromosome 6q24.2-q25.3. RAET1 proteins contain MHC class I-like alpha-1 and alpha-2 domains. RAET1E (MIM 609243) and RAET1G differ from the other RAET1 proteins (e.g., RAET1I, or ULBP1; MIM 605697) in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. (Radosavljevic et al., 2002 [PubMed 11827464]).[supplied by OMIM, Mar 2008]
GeneCards Summary for RAET1G Gene
RAET1G (Retinoic Acid Early Transcript 1G) is a Protein Coding gene. Among its related pathways are Immune response Role of DAP12 receptors in NK cells. GO annotations related to this gene include antigen binding and natural killer cell lectin-like receptor binding. An important paralog of this gene is ULBP3.
UniProtKB/Swiss-Prot for RAET1G Gene
Acts as a ligand for the KLRK1 receptor and mediates NK cell cytotoxicity via the receptor.