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RAET1E Gene

protein-coding   GIFtS: 56
GCID: GC06M150209

Retinoic Acid Early Transcript 1E

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Retinoic Acid Early Transcript 1E1 2 3     ULBP42 3
Lymphocyte Effector Toxicity Activation Ligand2 3     RAE-1-Like Transcript 42 3
LETAL2 3     RAET1E22
N2DL-42 3     bA350J20.72
NKG2DL42 3     NKG2D Ligand 42
RL-42 3     N2DL43

External Ids:    HGNC: 167931   Entrez Gene: 1352502   Ensembl: ENSG000001645207   OMIM: 6092435   UniProtKB: Q8TD073   

Export aliases for RAET1E gene to outside databases

Previous GC identifers: GC06M150164 GC06M150240 GC06M150297 GC06M150251 GC06M147775


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RAET1E Gene:
This gene belong to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related
genes located in a cluster on chromosome 6q24.2-q25.3. This and RAET1G protein differ from other RAET1 proteins
in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol
anchor sequences. This protein functions as a ligand for NKG2D receptor, which is expressed on the surface of
several types of immune cells, and is involved in innate and adaptive immune responses. Alternatively spliced
transcript variants encoding different isoforms have been found for this gene.(provided by RefSeq, Aug 2011)

GeneCards Summary for RAET1E Gene:
RAET1E (retinoic acid early transcript 1E) is a protein-coding gene. Diseases associated with RAET1E include cerebral angioma, and malignant glioma. GO annotations related to this gene include antigen binding and natural killer cell lectin-like receptor binding. An important paralog of this gene is ULBP1.

UniProtKB/Swiss-Prot: N2DL4_HUMAN, Q8TD07
Function: Ligand for the NKG2D receptor. Delivers activating signals to NK cells and promotes tumor immune
surveillance by inducing the expansion of anti-tumor cytotoxic lymphocytes

Gene Wiki entry for RAET1E Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000006.12  NC_018917.2  NT_025741.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the RAET1E gene promoter:
         STAT1   AML1a   NRSF form 1   STAT1beta   NRSF form 2   Pax-4a   STAT1alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRAET1E promoter sequence
   Search Chromatin IP Primers for RAET1E

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RAET1E


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q25.1   Ensembl cytogenetic band:  6q25.1   HGNC cytogenetic band: 6q24.3

RAET1E Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAET1E gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M150209:  view genomic region     (about GC identifiers)

Start:
150,204,511 bp from pter      End:
150,219,238 bp from pter
Size:
14,728 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: N2DL4_HUMAN, Q8TD07 (See protein sequence)
Recommended Name: NKG2D ligand 4 precursor  
Size: 263 amino acids; 30122 Da
Subunit: Binds to KLRK1/NKG2D. Does not interacts with the CMV glycoprotein UL16
Miscellaneous: The ULBPs are unusual members of the extended MHC class I superfamily, because they do not contain
the alpha 3 domain and they lack a transmembrane domain. They are unlikely to present peptides
Secondary accessions: A6YF59 Q5VYB7 Q5VYB8 Q8TEZ2 Q96L41
Alternative splicing: 4 isoforms:  Q8TD07-1   Q8TD07-2   Q8TD07-3   Q8TD07-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RAET1E: NX_Q8TD07

Explore proteomics data for RAET1E at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn36, Asn154, Asn212

  • See RAET1E Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001230254.1  NP_001230256.1  NP_001230257.1  NP_631904.1  

    ENSEMBL proteins: 
     ENSP00000437067   ENSP00000349709   ENSP00000376096   ENSP00000356332   ENSP00000432366  
     ENSP00000433489  
    Reactome Protein details: Q8TD07

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR011162 MHC_I/II-like_Ag-recog
     IPR011161 MHC_I-like_Ag-recog

    Graphical View of Domain Structure for InterPro Entry Q8TD07

    ProtoNet protein and cluster: Q8TD07

    1 Blocks protein domain: IPB001039 MHC class I signature

    UniProtKB/Swiss-Prot: N2DL4_HUMAN, Q8TD07
    Similarity: Belongs to the MHC class I family


    RAET1E for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: N2DL4_HUMAN, Q8TD07
    Function: Ligand for the NKG2D receptor. Delivers activating signals to NK cells and promotes tumor immune
    surveillance by inducing the expansion of anti-tumor cytotoxic lymphocytes

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003823antigen binding IBA--
    GO:0046703natural killer cell lectin-like receptor binding IPI15240696
         
    RAET1E for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RAET1E
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    miRNA
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    miRTarBase miRNAs that target RAET1E:
    hsa-mir-124-3p (MIRT022530)

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    N2DL4_HUMAN, Q8TD07: Membrane; Single-pass type I membrane protein
    N2DL4_HUMAN, Q8TD07: Isoform RAET1E2: Secreted
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    plasma membrane4
    endoplasmic reticulum1
    lysosome1
    peroxisome1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0005886plasma membrane TAS--
    GO:0016020membrane ----
    GO:0016021integral component of membrane IEA--

    RAET1E for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RAET1E About    
    See pathways by source

    SuperPathContained pathways About
    1Class I MHC mediated antigen processing and presentation
    Adaptive Immune System0.41
    2Immune response Role of DAP12 receptors in NK cells
    Natural killer cell mediated cytotoxicity0.31
    3Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
    Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for RAET1E
        Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell


    1 Kegg Pathway  (Kegg details for RAET1E):
        Natural killer cell mediated cytotoxicity


    RAET1E for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RAET1E
    Interactions:

        Search GeneGlobe Interaction Network for RAET1E

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RAET1E (Q8TD073 ENSP000003497094) via UniProtKB, MINT, STRING, and/or I2D (see all 45)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    KLRK1P267183, ENSP000002406184I2D: score=1 STRING: ENSP00000240618
    AZGP1ENSP000002924014STRING: ENSP00000292401
    B2MENSP000003408584STRING: ENSP00000340858
    CD1AENSP000002894294STRING: ENSP00000289429
    ENSG00000206435ENSP000003729754STRING: ENSP00000372975
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001913T cell mediated cytotoxicity IBA--
    GO:0006955immune response ----
    GO:0019882antigen processing and presentation IBA--
    GO:0042267natural killer cell mediated cytotoxicity IDA15240696
    GO:0050776regulation of immune response TAS--

    RAET1E for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RAET1E (N2DL4)

    1 Novoseek inferred chemical compound relationship for RAET1E gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    retinoic acid 65.3 1 14508119 (1)



    RAET1E for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for RAET1E gene (4 alternative transcripts): 
    NM_001243325.1  NM_001243327.1  NM_001243328.1  NM_139165.2  

    Unigene Cluster for RAET1E:

    Retinoic acid early transcript 1E
    Hs.511818  [show with all ESTs]
    Unigene Representative Sequence: AY359075
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000532335(uc003qnj.3) ENST00000357183(uc003qnl.1 uc003qnk.2 uc010kih.1)
    ENST00000392270 ENST00000367363 ENST00000529948(uc021zgq.1) ENST00000531073
    ENST00000524905
    miRNA
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      QuantiTect SYBR Green Assays in human, mouse, rat RAET1E
      QuantiFast Probe-based Assays in human, mouse, rat RAET1E

    Additional mRNA sequence: 

    AF359243.1 AY054974.1 AY069961.1 AY176317.1 AY252119.1 AY359075.1 BC103694.1 EF489426.1 

    3 DOTS entries:

    DT.97835189  DT.101976808  DT.99962906 

    12 AceView cDNA sequences:

    NM_139165 AY069961 AL602601 BM724657 AY176317 AY359075 AY252119 BU571097 
    AY054974 AF359243 BI258059 BE545401 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RAET1E expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    RAET1E Expression
    About this image


    RAET1E expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Endothelium (Cardiovascular System)
             Mature Endothelial Cells Blood Brain Barrier
     
     Brain (Nervous System)
             Mature Endothelial Cells Blood Brain Barrier
     
     Esophagus (Gastrointestinal Tract)
    RAET1E Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RAET1E Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.511818

    UniProtKB/Swiss-Prot: N2DL4_HUMAN, Q8TD07
    Tissue specificity: Predominantly expressed in the skin, but also expressed in testis and trachea. Up-regulated in
    tumor cells of different origins. Expression progressively decreased after treatment of tumor cells with retinoic
    acid

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and mouse.

    Orthologs for RAET1E gene from Selected species (see all 3)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Raet1e5 retinoic acid early transcript 1E   --   10 (9.89 cM) 22158569 


    ENSEMBL Gene Tree for RAET1E (if available)
    TreeFam Gene Tree for RAET1E (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RAET1E gene
    ULBP12  RAET1G2  ULBP32  RAET1L2  ULBP22  
    7 SIMAP similar genes for RAET1E using alignment to 6 protein entries:     N2DL4_HUMAN (see all proteins):
    RAET-1E    RAET1H    RAET1L    ULBP1    ULBP3    RAET1G
    ULBP2

    RAET1E for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RAET1E (see all 373)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2001899521,2
    C--150203813(+) TAAAA-/TTGTTATC 1 -- ds50010--------
    rs343591991,2
    C--150203817(+) AAATTGTT/-ATCTG 2 -- ds5001 cds11Minor allele frequency- -:0.50NA 2
    rs93970561,2
    C,F,A,H--150203858(+) CGAAGC/TGACAG 1 -- ds50019Minor allele frequency- T:0.32NS EA NA WA 774
    rs588892691,2
    C,F--150203917(+) TTAGGG/AAGACT 1 -- ds50011Minor allele frequency- A:0.50WA 2
    rs77650021,2
    C,F,H--150203930(+) AGGTTT/GAAAAT 1 -- ds50017Minor allele frequency- G:0.06NS EA WA CSA 542
    rs93835731,2
    C,F,A,H--150203953(+) ACATAT/CATTAT 1 -- ds50019Minor allele frequency- C:0.27NS EA NA CSA WA 725
    rs93970571,2
    C,F,A--150203995(+) GGAGTA/GAAAGT 1 -- ds50017Minor allele frequency- G:0.26NA WA EA 500
    rs1420846321,2
    --150204066(+) AACAGA/GGTTGC 1 -- ds50010--------
    rs1849898631,2
    --150204110(+) AATTAC/TCAGAT 1 -- ds50010--------
    rs1889785331,2
    --150204180(+) ATTACA/GTTTAT 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for RAET1E (150204511 - 150219238 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for RAET1E:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv819758CNV Loss19587683
    nsv886764CNV Loss21882294
    nsv886765CNV Gain21882294
    nsv517022CNV Gain+Loss19592680

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609243    OMIM disorders: --

    7 diseases for RAET1E:    
    About MalaCards
    cerebral angioma    malignant glioma    cerebritis    hepatitis b
    ovarian cancer    hepatitis    endotheliitis

    1 disease from the University of Copenhagen DISEASES database for RAET1E:
    Cerebral angioma

    RAET1E for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for RAET1E gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tumors 1.51 5 14508119 (3), 17470428 (2)

    Genetic Association Database (GAD): RAET1E
    Human Genome Epidemiology (HuGE) Navigator: RAET1E (3 documents)

    Export disorders for RAET1E gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RAET1E gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with RAET1E)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A cluster of ten novel MHC class I related genes on human chromosome 6q24.2-q25.3. (PubMed id 11827464)1, 2, 3 Radosavljevic M.... Bahram S. (Genomics 2002)
    2. Letal, a tumor-associated NKG2D immunoreceptor ligand, induces activation and expansion of effector immune cells. (PubMed id 14508119)1, 2, 9 Conejo-Garcia J.-R.... Coukos G. (Cancer Biol. Ther. 2003)
    3. Polymorphisms of NKG2D ligands: diverse RAET1/ULBP genes in northeastern Thais. (PubMed id 19688209)1, 4, 9 Romphruk A.V.... Leelayuwat C. (Immunogenetics 2009)
    4. ULBP4 is a novel ligand for human NKG2D. (PubMed id 12732206)1, 2, 9 Chalupny N.J....Cosman D. (Biochem. Biophys. Res. Commun. 2003)
    5. RAET1E2, a soluble isoform of the UL16-binding protein RAET1E produced by tumor cells, inhibits NKG2D-mediated NK cytotoxicity. (PubMed id 17470428)1, 2, 9 Cao W.... He W. (J. Biol. Chem. 2007)
    6. Single nucleotide polymorphism analysis of the NKG2D ligand cluster on the long arm of chromosome 6: Extensive polymorphisms and evidence of diversity between human populations. (PubMed id 20219610)1, 4, 9 Antoun A....Briggs D.C. (Hum. Immunol. 2010)
    7. Two human ULBP/RAET1 molecules with transmembrane regions are ligands for NKG2D. (PubMed id 15240696)1, 2, 9 Bacon L.... Trowsdale J. (J. Immunol. 2004)
    8. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (Nature 2003)
    9. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    10. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (Genes Immun. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 135250 HGNC: 16793 AceView: RAET1E Ensembl:ENSG00000164520 euGenes: HUgn135250
    ECgene: RAET1E Kegg: 135250 H-InvDB: RAET1E

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RAET1E Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RAET1E gene:
    Search GeneIP for patents involving RAET1E

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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